O protagonismo do indivíduo na sociedade hipermoderna

Este trabalho pretende discorrer sobre os vários signifi cados que o termo individualismo pode assumir na sociedade hipermoderna. Isso será feito a partir da elaboração de uma tipologia dos indivíduos: indivíduo pouco indivíduo; indivíduo muito indivíduo e indivíduo narcísico altruísta, mostrando que o último tipo é o que melhor expressa a sociedade de hoje: uma sociedade paradoxal na qual coabitam sentidos contrários. E é exatamente em função das contradições e paradoxos que se pode acenar com otimismo para as possibilidades do indivíduo: ele pode ser, a um só tempo, obcecado por si mesmo e sensível ao outro.

Hilda Hilst e a (im)possibilidade de (se) dizer

Investiga-se em que medida Hilda Hilst, em Fluxo-floema, vale-se de um conjunto de procedimentos que colocam em cena tanto o sujeito-narrador quanto o próprio narrar, de maneira destoante do que predominantemente se fazia à época. Se no contexto ditatorial era tendência relacionar a literatura a uma “função compensatória”, o que a autora oferece em sua estreia na prosa mostra-se de modo ambivalente, já que não abdica desse prisma, porém o relaciona à frustração. No caso do texto “Osmo”, isso se dá à medida em que se instaura um descompasso entre o “narrar prometido” e o “narrar empreendido”, o que acaba por evidenciar tanto o texto como construção verbal encenada quanto a ambígua atitude do narrador-personagem diante da necessidade de verbalizar a sua história e de se aproximar de seus receptores. O postergamento da história prometida gera a frustração, que é alegoricamente abarcada como um procedimento de tessitura do texto hilstiano relacionado à ironia, à violência, ao fracasso, e que ilumina a condição paradoxal do narrar e da relação do/da artista com o mercado literário.

Os tons de Zé: transformações paradigmáticas na obra de Tom Zé (1967-1976)

Pós-graduação em Música - IA

A extensão da racionalidade econômico-privatistica ao conhecimento produzido pela subjetividade emancipada: paradoxo da modernidade

This paper aims to present a study of the social relationships around the production, circulation and the eventual possibility of appropriation of knowledge in social systems of the pre-modern world and in a social organization of Western capitalist modernity. In this specific universe of relationships, it was also important to noticed that there is a paradoxical role of rationality that served to the emancipation of instruments of control’s knowledge of pre-modern period as in the same time it was favored by the construction of new bonds that were made in the Western modernity through the modern legal system, inserting the knowledge in the domain of the economy and private logic of the capitalist’s system through intellectual property. This research was made from a review of the literature, using specialized books of the theme. It was concluded that there is a paradox in the social relationships about the knowledge, whose cause is related to the unfolding of rationality in the development of Western civilization.

Memória, culpa e angústia nas narrativas de Alice Munro e Clarice Lispector

This study analyses two writers from different nationalities and cultures, the Brazilian Clarice Lispector and the Canadian Alice Munro, to demonstrate the common treatment that both writers give to the childhood theme. The central aim is to examine, with the support of Freud‘s psychoanalytic studies, how childhood is important to understand the writers‘ fiction, or when a narrative voice revisits experiences lived in that period, or when the narrative is dominated by a childlike voice. In both events, memory is the central element in this anamnesis process. We seek to prove that even when dealing with different cultures, it is possible to develop a comparative study to show similar strategies applied by the writers. The selected narratives show relevant information concerning the chosen theme and enable to reveal the mode of composition and the concept of literary creation of each author. The analytical study of the narrative categories, especially the narrator, time and space, will be examined to show how they influence on the construction of the theme. Other features will provide support for the analysis, such as internalized narrative, the open end, the constant temporal and spatial distortions, the use of contradictory figures of speech such as oxymoron, unusual metaphors and antitheses, the portrayal of a paradoxical world and the concern with existential questions, all of which are shared by the authors, in addition to the theme, which allow the comparative work

Uma estética do paradoxo: aspectos do melodrama no romance latino-americano do pós-boom

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

O Heitor de Homero e as diversas faces do medo

Pós-graduação em Estudos Literários - FCLAR

Gastric and small intestinal lesions after partial stomach resection with Billroth II or Roux-en-Y reconstruction in the rat

The evolution and phenotypic expression of mucosal lesions of the gastric stump were investigated in male rats submitted to gastric resection with reconstruction by the Billroth II technique (BII with biliopancreatic reflux, BPR) or by the Roux-en-Y procedure (without BPR). Animals were studied at 24, 36, 54 and 64 weeks after surgery and the phenotypic expression of lesions analysed using routine hematoxylin and eosin staining, immunohistochemical staining for pepsinogen isoenzyme 1 and histochemical procedures for mucins (paradoxical concanavalin A, galactose oxidase Schiff (GOS) and sialidase GOS reactions). BPR was found to be responsible for the formation of adenomatous hyperplasia (AH), increasing in incidence and size with time, since the Roux-en-Y procedure failed to induce the gastric stump lesions observed after BII reconstruction. AHs always occurred in the transition of the gastrojejunal junction, a site offering special conditions for BPR influence, and were classified as gastric (G), intestinal (I) and G+I types according to their phenotypic expression. No pure I type AH was diagnosed at any time point. The G and G+I types developed at approximately equal incidences (i.e., G type 7/17, G+I type 10/17 at the 64th week). It was suggested that both gastric and intestinal mucosal elements were stimulated to proliferate by BPR, with the gastric mucosa tending to demonstrate AH. Intestinal type components of AH were found adjacent to the jejunum and not at the stomach margin, indicating an origin from intestinal mucosa. No metaplasia of the gastric mucosa was observed in any animal after partial gastric resection. In 101 rats submitted to the BII procedure, 5 mucinous adenocarcinomas were eventually diagnosed, mostly located in the subserosa of the gastrojejunal junction. All carcinomas expressed the phenotype of cells of the small intestine. Evidence of malignant transformation within the gastric components of AH was not observed even at the 64th week. In conclusion, all lesions induced by BPR in the rat remnant stomach are benign, and the few true cancers that arise in association are derived from the small intestine.

The presence of the NOS3 gene polymorphism for intron 4 mitigates the beneficial effects of exercise training on ambulatory blood pressure monitoring in adults

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Sodium intake, brain c-Fos protein and gastric emptying in cell-dehydrated rats treated with methysergide into the lateral parabrachial nucleus

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

O discurso do humor politicamente incorreto no mundo contemporâneo

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Índices de erotismo no discurso machadiano

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A possible increase of activity of endothelial l-arginine/nitric oxide pathway in aortas of diet-induced obesity rats

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Antiresorptive drugs (bisphosphonates), atypical fractures and rebound effect: new evidence of similitude

Background: Homeopathy is based on treatment by similitude ('like cures like') administering to sick individuals substances that cause similar symptoms in healthy individuals, employing the secondary and paradoxical action of the organism as therapeutic response. This vital or homeostatic reaction of the organism can be scientifically explained by the rebound effect of drugs, resulting in worsening of symptoms after suspension of treatment. Bisphosphonates (BPs) reduce 'typical' fractures in patients with osteoporosis, but recent studies report 'atypical' fractures of the femur after stopping the BPs, a rebound effect may be the causal mechanism. Method: Review of the literature concerning the relationship between atypical femoral fractures and antiresorptive drugs (bisphosphonates), identifying the pathogenesis of this adverse event. Results: Several studies have described multiple cases of 'atypical' low-impact subtrochanteric stress fractures or complete fractures of the femur. These fractures are often bilateral, preceded by pain in the affected thigh, may have a typical X-ray appearance, and may delayed healing. Rebound of osteoclastic activity after suspension of antiresorptive drugs is a plausible mechanism to explain this phenomenon. Conclusion: As for other classes of drugs, the rebound effect of antiresorptive drugs supports Hahnemann's similitude principle (primary action of the drugs followed by secondary and opposite action of the organism), and clarifies this 'unresolved' issue. Unfortunately, the rebound effect is little discussed among health professionals, depriving them of important knowledge ensure safe management of drugs. Homeopathy (2012) 101, 231-242.

Treatment of severe forms of paracoccidioidomycosis: is there a role for corticosteroids?

Despite their immunosuppressive effects, corticosteroids have long been used as adjunct therapy (aCST) in the treatment of infectious diseases. The rationale is that in certain infections it is necessary to decrease the exacerbated host's inflammatory response, which can otherwise result in tissue damage and organ dysfunction. In fact, a major concern in treating paracoccidioidomycosis (PCM) is the host's intense inflammatory response to Paracoccidioides brasiliensis, which can be further intensified by antifungal therapy. Depending on its localization, this immunological phenomenon may be life threatening or result in permanent sequels, as is the case for some patients with cerebral or laryngeal involvement. However, the literature on aCST in paracoccidioidomycosis treatment is scarce and as a result we present our recent experience in the management of four patients with severe PCM manifestations, i.e., cerebral paracoccidioidal granuloma, laryngeal stenosis, compressive abdominal mass, and exacerbated inflammatory response with tissue destruction. In addition to the antifungal therapy, these patients required aCST, which probably promoted their clinical improvement and/or prevented serious complications. We suggest that aCST: (a) can potentially help in the management of selected cases of severe forms of PCM, particularly when there is a risk of acute complications, and (b) that it can be used safely provided that the risk-benefit ratio is carefully weighed. Well-controlled, prospective studies of aCST in the treatment of severe cases of paracoccidioidomycosis are needed to better define its role in the management of PCM.