879 resultados para Egocentric Constraint
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Project Management involves onetime endeavors that demand for getting it right the first time. On the other hand, project scheduling, being one of the most modeled project management process stages, still faces a wide gap from theory to practice. Demanding computational models and their consequent call for simplification, divert the implementation of such models in project management tools from the actual day to day project management process. Special focus is being made to the robustness of the generated project schedules facing the omnipresence of uncertainty. An "easy" way out is to add, more or less cleverly calculated, time buffers that always result in project duration increase and correspondingly, in cost. A better approach to deal with uncertainty seems to be to explore slack that might be present in a given project schedule, a fortiori when a non-optimal schedule is used. The combination of such approach to recent advances in modeling resource allocation and scheduling techniques to cope with the increasing flexibility in resources, as can be expressed in "Flexible Resource Constraint Project Scheduling Problem" (FRCPSP) formulations, should be a promising line of research to generate more adequate project management tools. In reality, this approach has been frequently used, by project managers in an ad-hoc way.
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Dissertação de mestrado integrado em Engenharia Biomédica
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Tese de Doutoramento em Tecnologias e Sistemas de Informação
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Tese de Doutoramento em Estudos da Criança (Especialidade em Educação Musical)
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PhD thesis in Biomedical Engineering
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Architectural (bad) smells are design decisions found in software architectures that degrade the ability of systems to evolve. This paper presents an approach to verify that a software architecture is smellfree using the Archery architectural description language. The language provides a core for modelling software architectures and an extension for specifying constraints. The approach consists in precisely specifying architectural smells as constraints, and then verifying that software architectures do not satisfy any of them. The constraint language is based on a propositional modal logic with recursion that includes: a converse operator for relations among architectural concepts, graded modalities for describing the cardinality in such relations, and nominals referencing architectural elements. Four architectural smells illustrate the approach.
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This chapter deals with the characterization of the basic constraints between two vectors. This issue plays a crucial role in the formulation of constraint equations for mechanical joints. In particular, relations between two parallel and two perpendicular vectors are derived. Moreover, formulation for a vector that connects two generic points is presented. The material described here is developed under the framework of multibody systems formulation for spatial systems.
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"Series title: Springerbriefs in applied sciences and technology, ISSN 2191-530X"
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"Series title: Springerbriefs in applied sciences and technology, ISSN 2191-530X"
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Under the framework of constraint based modeling, genome-scale metabolic models (GSMMs) have been used for several tasks, such as metabolic engineering and phenotype prediction. More recently, their application in health related research has spanned drug discovery, biomarker identification and host-pathogen interactions, targeting diseases such as cancer, Alzheimer, obesity or diabetes. In the last years, the development of novel techniques for genome sequencing and other high-throughput methods, together with advances in Bioinformatics, allowed the reconstruction of GSMMs for human cells. Considering the diversity of cell types and tissues present in the human body, it is imperative to develop tissue-specific metabolic models. Methods to automatically generate these models, based on generic human metabolic models and a plethora of omics data, have been proposed. However, their results have not yet been adequately and critically evaluated and compared. This work presents a survey of the most important tissue or cell type specific metabolic model reconstruction methods, which use literature, transcriptomics, proteomics and metabolomics data, together with a global template model. As a case study, we analyzed the consistency between several omics data sources and reconstructed distinct metabolic models of hepatocytes using different methods and data sources as inputs. The results show that omics data sources have a poor overlapping and, in some cases, are even contradictory. Additionally, the hepatocyte metabolic models generated are in many cases not able to perform metabolic functions known to be present in the liver tissue. We conclude that reliable methods for a priori omics data integration are required to support the reconstruction of complex models of human cells.
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Dissertação de mestrado em Ciências da Comunicação (área de especialização em Informação e Jornalismo)
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"Series: Solid mechanics and its applications, vol. 226"
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Devido à elevada dimensão espacial e temporal da maior parte dos fenómenos geológicos, não é possível reproduzir no laboratório os fenómenos a estudar, pelo que, se o professor de Geologia pretender colocar os alunos em contato com esses fenómenos, terá que organizar uma saída de campo para que as necessárias e adequadas atividades sejam realizadas no lugar onde esses fenómenos ocorrem. Contudo, e apesar de professores e alunos reconhecerem diversas potencialidades didáticas das saídas de campo, os professores raramente as organizam e justificam isso com base em diversos impedimentos. Neste artigo relatam-se os resultados de um estudo em que 233 professores portugueses de Biologia e Geologia foram inquiridos acerca de formas ideais de integrar as atividades de campo na componente de Geologia, no 3º ciclo do Ensino Básico (n=102) e no Ensino Secundário (n=131). Os resultados sugerem que as práticas que os professores gostariam de implementar, caso não houvesse constrangimentos à realização de atividades de campo, não seriam, na maior parte dos casos, muito diferentes das práticas implementadas que são relatadas na literatura. Esta falta de exigência e de ousadia por parte dos professores, no que concerne ao modo como as atividades de campo deveriam ser utilizadas, sugere a necessidade de a formação inicial e contínua de professores contemplar uma abordagem adequada das saídas de campo e de as escolas se reorganizarem para facilitarem a organização, fundamentada, das mesmas.
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O presente estudo tem como objectivo perceber como o clima afectivo (positivo ou negativo) induzido pelo treinador influencia o comportamento táctico e o estado afectivo percepcionado pelos jogadores de futebol Sub-15 do Campeonato Distrital da Associação de Futebol de Lisboa. Seleccionaram-se três equipas que constituíram os três grupos do estudo: grupo de afectividade positiva (GAP), grupo de afectividade negativa (GAN) e o grupo controlo (GC). Após um pré-teste, à excepção do GC, com manifestação de afectividade neutra pelo treinador, os grupos experimentais foram submetidos a situações de afectividade positiva e negativa, durante três sessões de treino. Após este período de intervenção, realizou-se um pós-teste. Avaliou-se afectos percepcionados pelos jogadores, através da escala PANAS e o comportamento táctico, através da largura de jogo da equipa, com base na recolha de dados posicionais, verificando-se a regularidade da largura de jogo através da entropia amostral (SampEn). Foram encontradas diferenças significativas na regularidade do comportamento no GAN ̅ e ̅ mas não se encontraram diferenças nos afectos percepcionados pelos jogadores em nenhum dos grupos. Encontrou-se igualmente uma tendência positiva na largura da equipa no GAP. Os resultados sugerem que o clima afectivo do treinador apresenta-se como um constrangimento ambiental que influência o comportamento táctico dos jogadores. O clima afectivo positivo estabeleceu um aumento da largura da equipa, mostrando-se viável à procura de comportamentos adaptativos para a consecução de objectivos estabelecidos.
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This paper investigates the role of variable capacity utilization as a source of asymmetries in the relationship between monetary policy and economic activity within a dynamic stochastic general equilibrium framework. The source of the asymmetry is directly linked to the bottlenecks and stock-outs that emerge from the existence of capacity constraints in the real side of the economy. Money has real effects due to the presence of rigidities in households' portfolio decisions in the form of a Luces-Fuerst 'limited participation' constraint. The model features variable capacity utilization rates across firms due to demand uncertainty. A monopolistic competitive structure provides additional effects through optimal mark-up changes. The overall message of this paper for monetary policy is that the same actions may have different effects depending on the capacity utilization rate of the economy.