Metabolic Effects of the Ingestion of Different Fructose Sources in Rats

Introduction: Fructose is a simple carbohydrate that should be ingested in a restricted manner. However, current data suggest increased daily consumption of fructose which may lead to an increased incidence of diseases such as obesity, diabetes and co-morbidities associated with excess weight. Thus, the objective of the present study was to assess the effect of the ingestion of different fructose sources on weight gain, glycemia and serum triglyceride levels in rats.Methods: The study was conducted on male Wistar rats divided into 5 groups according to the source and concentration of fructuse (ingested ad libitum in liquid form).Results: Drink intake was increased and chow consumption was reduced in all groups compared to control (p<0.05). The animals of the groups receiving 10 and 20% fructose solutions showed increased triglyceride levels and the 20% group also showed weight gain. The exaggerate consumption of fructose promotes a reduced consumption of chow, an increase in serum triglyceride levels, and weight gain in some animals.

Fructose in fetal cord blood and its relationship with maternal and 48-hour-newborn blood concentrations

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Aerobic capacity of rats recovered from fetal malnutrition with a fructose-rich diet

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Recovery of rat growth and lipid profiles in adult rats subjected to fetal protein malnutrition with a fructose-rich diet

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Exercise counteracts fatty liver disease in rats fed on fructose-rich diet

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Impact of early fructose intake on metabolic profile and aerobic capacity of rats

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Metabolic responses to acute physical exercise in young rats recovered from fetal protein malnutrition with a fructose-rich diet

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Fructose-rich diet leads to reduced aerobic capacity and to liver injury in rats

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Glucose and Fructose Fermentation by Wine Yeasts in Media Containing Structurally Complex Nitrogen Sources

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