Cationic Diffusion in La2/3Ca1/3MnO3 Thin Films Grown on LaAlO3 (001) Substrates.

Microstructural features of La2/3Ca1/3MnO3 layers of various thicknesses grown on top of 001 LaAlO3 substrates are studied by using transmission electron microscopy and electron energy loss spectroscopy. Films are of high microstructural quality but exhibit some structural relaxation and mosaicity both when increasing thickness or after annealing processes. The existence of a cationic segregation process of La atoms toward free surface has been detected, as well as a Mn oxidation state variation through layer thickness. La diffusion would lead to a Mn valence change and, in turn, to reduced magnetization.

Coverage effects on the magnetism of Fe/MgO(001) ultrathin films

Different aspects of the structure-magnetism and morphology-magnetism correlation in the ultrathin limit are studied in epitaxial Fe films grown on MgO(001). In the initial stages of growth the presence of substrate steps, intrinsically higher than an Fe atomic layer, prevent the connection between Fe islands and hence the formation of large volume magnetic regions. This is proposed as an explanation to the superparamagnetic nature of ultrathin Fe films grown on MgO in addition to the usually considered islanded, or Vollmer-Weber, growth. Using this model, we explain the observed transition from superparamagnetism to ferromagnetism for Fe coverages above 3 monolayers (ML). However, even though ferromagnetism and magnetocrystalline anisotropy are observed for 4 ML, complete coverage of the MgO substrate by the Fe ultrathin films only occurs around 6 ML as determined by polar Kerr spectra and simulations that consider different coverage situations. In annealed 3.5 ML Fe films, shape or configurational anisotropy dominates the intrinsic magnetocrystalline anisotropy, due to an annealing induced continuous to islanded morphological transition. A small interface anisotropy in thicker films is observed, probably due to dislocations observed at the Fe¿MgO(001) interface.

Nitrogen incorporation effects in Fe(001) thin films

Nitrogen incorporates into Fe thin films during reactively sputtered TiN capping layer deposition. The influence that this nitrogen incorporation has both on the structure and magnetic properties is discussed for a series of Fe~001! thin films grown at different temperatures. A higher nitrogen content is accompanied by distortion in the Fe lattice and by reduction in the Fe magnetization saturation as well as in the effective anisotropy constant, K. The reduction of K brings as a consequence lowering in the coercive field with respect to equivalent Fe films with no nitrogen present.

Magnetization reversal and magnetic anisotropies in epitaxial Fe/MgO and Fe/MgO/Fe heterostructures grown on Si(001)

Epitaxial Fe/MgO heterostructures have been grown on Si(001) by a combination of sputtering and laser ablation deposition techniques. The growth of MgO on Si(001) is mainly determined by the nature of the interface, with large lattice mismatch and the presence of an amorphous layer of unclear origin. Reflection high energy electron diffraction patterns of this MgO buffer layer are characteristic of an epitaxial, but disordered, structure. The structural quality of subsequent Fe and MgO layers continuously improves due to the better lattice match and the burial of defects. A weak uniaxial in-plane magnetic anisotropy is found superimposed on the expected cubic biaxial anisotropy. This additional anisotropy, of interfacial nature and often found in Fe/MgO and Fe/MgO/GaAs(001) systems, is less intense here due to the poorer MgO/Si interface quality compared with that of other systems. From the evolution of the anisotropy field with film thickness, magnetic anisotropy is also found to depend on the crystal quality. Kerr measurements of a Fe/MgO multilayered structure grown on Si show two different switching fields, suggesting magnetic coupling of two of the three Fe layers. Nevertheless, due to the little sensitivity to the bottom Fe film, independent switching of the three layers cannot be ruled out.

Clinical benefit and quality of life in patients with advanced pancreatic cancer receiving gemcitabine plus capecitabine versus gemcitabine alone: a randomized multicenter phase III clinical trial--SAKK 44/00-CECOG/PAN.1.3.001.

PURPOSE: To compare clinical benefit response (CBR) and quality of life (QOL) in patients receiving gemcitabine (Gem) plus capecitabine (Cap) versus single-agent Gem for advanced/metastatic pancreatic cancer. PATIENTS AND METHODS: Patients were randomly assigned to receive GemCap (oral Cap 650 mg/m(2) twice daily on days 1 through 14 plus Gem 1,000 mg/m(2) in a 30-minute infusion on days 1 and 8 every 3 weeks) or Gem (1,000 mg/m(2) in a 30-minute infusion weekly for 7 weeks, followed by a 1-week break, and then weekly for 3 weeks every 4 weeks) for 24 weeks or until progression. CBR criteria and QOL indicators were assessed over this period. CBR was defined as improvement from baseline for >or= 4 consecutive weeks in pain (pain intensity or analgesic consumption) and Karnofsky performance status, stability in one but improvement in the other, or stability in pain and performance status but improvement in weight. RESULTS: Of 319 patients, 19% treated with GemCap and 20% treated with Gem experienced a CBR, with a median duration of 9.5 and 6.5 weeks, respectively (P < .02); 54% of patients treated with GemCap and 60% treated with Gem had no CBR (remaining patients were not assessable). There was no treatment difference in QOL (n = 311). QOL indicators were improving under chemotherapy (P < .05). These changes differed by the time to failure, with a worsening 1 to 2 months before treatment failure (all P < .05). CONCLUSION: There is no indication of a difference in CBR or QOL between GemCap and Gem. Regardless of their initial condition, some patients experience an improvement in QOL on chemotherapy, followed by a worsening before treatment failure.

[Voyage en Italie : 1824-1830]. , S. Gennaro de Poveri à Naples, sur une échelle de 0,001 1/2 PM : [plan d'ensemble, coupe longitdinale et élévation principale] : [dessin] / h. L. [Henri Labrouste]

Référence bibliographique : Weigert, 225

[Voyage en Italie : 1824-1830]. , Palazzo Stella. Sur une échelle de 001 P. M. : [plan d'ensemble, plan de l'escalier au 1er étage] : [dessin] / h. L. [Henri Labrouste]

Référence bibliographique : Weigert, 58

[Voyage en Italie : 1824-1830]. , Temple d'Isis, sur une Echelle de 001 PM : [coupe transversale, coupe longitudinale, détail ornemental] : [dessin] / h. L. [Henri Labrouste]

Référence bibliographique : Weigert, 368

[Voyage en Italie : 1824-1830]. , Coupe du Temple de Jupiter. Coupe du Forum. Sur une Echelle de 001 PM : [coupe longitudinale sur le temple, coupe transversale sur le forum] : [dessin] / h. L. [Henri Labrouste]

Référence bibliographique : Weigert, 371

09002-001 Indian Springs Pond Watershed Final Report

Silver Creek is a warm water stream resource located in one of the most intensely cropped portions of Clayton County. The stream has been included on Iowa’s 303(d) list of impaired waters since 2002. Aquatic life, which should be present in Silver Creek, isn’t there. According to the Draft Total Maximum Daily Load (TMDL) for Silver Creek, the primary nonpoint pollution sources are soil erosion from agricultural land uses and direct deposition of ammonia by livestock with access to the stream. The Clayton Soil & Water Conservation District has begun efforts to remove Silver Creek from the impaired waters list. The District has promoted stream corridor and sinkhole protection, and the installation of buffer practices along Silver Creek and its tributaries. Conservation practices have been targeted to crop fields to reduce sediment delivery to the stream. A series of news articles, newsletters, and field days have been utilized to increase public understanding of water quality issues. Landowner interest has outweighed available cost share resources. Additional financial support will allow the project to build upon its early successes, to further address the identified impairments, and to respond to a long list of landowners that are interested in conservation work on their farms.

08004-001 Summit Lake Final Report

The Summit Lake Watershed Improvement Project is a watershed-based sediment control project designed to greatly reduce to nearly eliminate sedimentation of an existing lake that is being renovated for use as a water source in southern Iowa. Summit Lake is owned by the City of Creston and was once a water source lake until around 1984. The watershed improvements will include lakeshore stabilization and erosion control practices as a precursor for related improvements to the lake and overall 4,900-acre watershed. Best practices included in this phase are the implementation of riprap, a rain garden, grade stabilization structures, grassed waterways, terraces, basins, water use and access ordinances, education and outreach, water monitoring, and other stream bank improvements. These improvements, along with leveraged work to be done by strategic partners, will enable the lake to be used for local and regional water supplies by sustaining the lake for many years to come. Without the lake rehabilitation, the lake will likely be filled with sedimentation to the point that it will have no recreational value. Key partners are the City of Creston, IDNR, Southern Iowa Rural Water Association, Union County, the Union County NRCS office, Southwestern Community College, and the Summit Lake Association, which is a non-profit group of landowners working to protect the lake. The project will address WIRB targets: a) streambank stabilization, b) livestock runoff, c) agricultural runoff and drainage, d) stormwater runoff, and e) a section of inadequately sewered community.

1102-001 Twelve Mile Lake Final Report

Twelve-Mile Lake is an 800-acre man-made lake in central Union County. The watershed has 13,964 land acres that are used by farmers for row crops and pasture. This lake is used as a water supply source for the City of Creston and the Southern Iowa Rural Water Association. In total approximately 40,000 people are affected by this project. Developed over 20 years ago, the lake and fishery was renovated and restocked and much of the shoreline was riprapped about six years ago. During its history, extensive watershed efforts have been ongoing. However, as farmland for cropland has become more valuable and demand has increased, hilly land once used for dairy farming, grazing, and CRP has been put into row crop production. Consequently, sediment loss has become an increasing issue for farmers, conservation professionals, and the Creston Waterworks Department, which owns the water treatment facility at the lake. In 2011, the Creston Water Board received a WIRB grant to implement a sedimentation structure at the north end of the main channel flowing into the lake. The WIRB funds were used for land acquisition, with the IDNR actually constructing the facility. This report depicts work performed as part of the WIRB project.