Tackling Societal Challenges Related to Ageing and Transport Transition: An Introduction to Philosophical Principles of Causation Adapted to the Biopsychosocial Model

In geriatrics, driving cessation is addressed within the biopsychosocial model. This has broadened the scope of practitioners, not only in terms of assessing fitness to drive, but also by helping to maintain social engagements and provide support for transport transition. Causes can be addressed at different levels by adapting medication, improving physical health, modifying behaviour, adapting lifestyle, or bringing changes to the environment. This transdisciplinary approach requires an understanding of how different disciplines are linked to each other. This article reviews the philosophical principles of causality between fields and provides a framework for understanding causality within the biopsychosocial model. Understanding interlevel constraints should help practitioners overcome their differences, and favor transversal approaches to driving cessation.

Els recursos en l'aprenentatge de les Matemàtiques : un model per a l'EGB. 'El aprendizaje de las Matemáticas : un modelo para EGB'.

Crear un material de apoyo en el aula válido para el aprendizaje del tema 'los números enteros' de séptimo curso de EGB, que sea motivador para el alumno. 90 alumnos de la escuela pública de Sant Por de Mar, distribuidos a los tratamientos según un diseño de Solomón. Realiza una introducción teórica desde la psicología del niño, orientación, contenidos y tecnología educativa. Pasando a la elaboración de la metodología de trabajo y el material a utilizar. Realiza el diseño experimental (de Solomón) de la investigación realizando pretest y posttest, y extrayendo conclusiones del análisis de los datos sobre el material y el método. Creación de un (test de rendimiento) test de instrucción con 20 ítems. Encuesta basada en la técnica de observación directa y elaborada sobre la base de la prueba '¿qué opinas sobre tí mismo?' de la Universidad de Mariland. Comparación de medias entre grupos acorde con el diseño empleado. Estudio de la prueba: índice de dificultad y fiabilidad. Índices estadísticos y representaciones gráficas. Análisis de varianza. Respecto al material: el material gráfico impreso ofrece al maestro un medio de trabajo motivador en contenido y forma, es efectivo para el aprendizaje, y puede potenciar el cálculo mental rápido sin ocupar un tiempo excesivo, siendo además flexible y adaptable a cualquier metodología. Respecto al método: aporta material de trabajo numeroso, susceptible de ser utilizado total o parcialmente, y aceptado por el discente como útil y motivador.

L'enriquiment instrumental segons R. Feuerstein : vers la caracterització d'un model d'acció pedagògica per a l'adquisició d'habilitats de pensament. 'El enriquecimiento instrumental según R. Feuerstein : hacia la caracterización de un modelo de acción pedagógica para la adquisición de habilidades de pensamiento'.

Valorar el modelo de Feuerstein (FIE) en su ámbito de adquisición de habilidades de pensamiento, en alumnos de escolaridad normal, desde la perspectiva de la acción pedagógica y desde una óptica teórica y experimental. Grupo experimental: 85 alumnos de sexto nivel de EGB, de un centro privado, procedentes de familias de status socioeconómico medio-alto, del curso académico 1986-87 y 1987-88. Grupo control: alumnos de las mismas características que los anteriores de otro centro privado. Describe la teoría y materiales de Feuerstein. Discusión de las bases teóricas del FIE. Valora el programa y lo contrasta con otros modelos. Experimenta el modelo para evaluar las aptitudes mentales que mejoran en los alumnos después de la aplicación del programa. Plantea un diseño con grupo control pretest posttest. V.I.: Participación o no en el programa. V.D.: Mejora en las aptitudes. Controla variables intervinientes. Aplica el programa al grupo experimental y una batería de tests pretest y posttest a los dos grupos para medir las aptitudes. Analiza los datos y complementa los resultados con un un estudio sobre las actitudes del profesorado y los alumnos hacia el FIE. Instrumentos del programa: organización de puntos, orientación espacial I y II, comparaciones, clasificaciones, percepción analítica y relaciones familiares. Batería de tests: test de comprensión verbal, test de fluidez verbal, test de razonamiento abstracto, test de aptitud numérica, test de comprensión espacial, test de memoria y test de rapidez perceptiva. ANCOVA, ANOVA, t de Student, índices de fiabilidad y validez y representaciones gráficas. El FIE mejora fluidez verbal y rapidez perceptiva. Potencia la eficacia en tareas donde se requiere una estrategia sencilla. Es suficiente para desarrollar el razonamiento abstracto, la memoria o el razonamiento numérico. Puede contrarestar déficits en la comprensión verbal pero no mejora el razonamiento espacial. Los alumnos tienen una opinión positiva hacia el FIE y los profesores creen que los alumnos han mejorado en sus hábitos de estudio, autoconcepto y capacidad de comunicación verbal, pero no puede generalizarse una mejora en el rendimiento académico. El modelo cognitivo-natural de acción pedagógica en el ámbito de la adquisición de habilidades de pensamiento queda corroborado. Es uno de los programas más completos para aprender a pensar. Plantea la prospectiva de investigar los efectos del FIE en la esfera emotiva, mejorar los instrumentos de medida y estudiar el grado de generabilidad de las conclusiones.

Model d'indicadors per l'avaluació i gestió de qualitat de centres i districtes : Saporei. 'Modelo de indicadores para la evaluación y gestión de calidad en centros y distritos : Saporei'.

Definir nuevas estrategias de evaluación y mejora de centros educativos a partir de un conjunto de indicadores de calidad. La base experiencial del estudio está centrada en la experiencia de formación del profesorado institucional (FOPI) de Cornellà. También se incluyen experiencias diversas de asesoramiento a centros de profesores o de evaluación de programas (experiencia Logo y proyecto Atenea) que inciden en el papel del asesor en la evaluación de un centro. Se parte del análisis de las teorías y experiencias que sobre evaluación se han desarrollado en Cataluña, España y extranjero; son el soporte teórico del modelo elaborado: Saporei. La presentación del modelo incluye una vertiente sobre todo tecnológica de evaluación, la descripción de los indicadores de calidad educativa Saporei, sus posibilidades de uso y las consideraciones sobre la política evaluativa. A continuación se hace referencia a las bases experienciales en las que se fundamenta para llegar a una propuesta de evaluación de centros educativos. Informes. Tablas de datos: escolares, distritos, centros, económicas. Cuadros comparativos. Instrumentos de evaluación: Quafe-80, PVH/87, etc. Análisis descriptivo. Los indicadores escolares no gozan aún de una valoración general ni entre la población ni tampoco entre los mismos especialistas en Ciencias de la Educación. Los indicadores se acostumbran a elaborar después de la toma de decisiones, perdiendo así su sentido de previsión y planificación. Además los indicadores elaborados a partir de datos estadísticos disponibles no son tratados como debieran. Los indicadores no sirven para aumentar el nivel cualitativo de la educación. No hay consenso en su construcción como tampoco una utilización generalizada. La integración y relación entre macroindicadores, indicadores del entorno (distrito) e indicadores del centro escolar nos proporcionan nuevas posibilidades de interpretación y de orientación de acciones de políticas de centros escolares más adecuadas y adaptadas a las situaciones y demandas. Un sistema de indicadores no puede estar definido únicamente desde arriba, sino también desde el propio centro escolar. Se ha de profundizar en los sistemas de indicadores de centro escolar para ir expandiéndolo progresivamente a otros niveles del sistema socio-cultural.

Estudo do papel da proteína multifuncional APE1/Ref-1 sobre a resposta inflamatória na meningite bacteriana

Despite advances in antibiotic therapy, bacterial meningitis (BM) remains with high mortality and morbidity rates in worldwide. One important mechanism associated to sequels during disease is the intense inflammatory response which promotes an oxidative burst and release of reactive oxygen species, consequently leading to cell death. Activation of DNA repair enzymes during oxidative stress has been demonstrated in several neurological disorders. APE1/Ref-1 is a multifunctional protein involved in DNA repair and plays a redox function on transcription factors such as NFkB and AP-1.The aim of this study was assess the role of APE1/Ref-1 on inflammatory response and the possibility of its modulation to reduce the sequels of the disease. Firstly it was performed an assay to measure cytokine in cerebrospinal fluid of patients with BM due to Streptococcus pneumoniae and Neisseriae meningitides. Further, a cellular model of inflammation was used to observe the effect of the inhibition of the endonuclease and redox activity of APE1/Ref-1 on cytokine levels. Additionally, APE1/Ref-1 expression in cortex and hippocampus of rat with MB after vitamin B6 treatment was evaluated. Altogether, results showed a similar profile of cytokines in the cerebrospinal fluid of patients from both pathogens, although IFNy showed higher expression in patients with BM caused by S. pneumoniae. On the other hand, inhibitors of APE1/Ref-1 reduced cytokine levels, mainly TNF-α. Reduction of oxidative stress markers was also observed after introduction of inhibitors in the LPS-stimulated cell. In the animal model, BM increased the expression of the protein APE1/Ref-1, while vitamin B6 promoted reduction. Thereby, this data rise important factors to be considered in pathogenesis of BM, e.g., IFNy can be used as prognostic factor during corticosteroid therapy, APE1/Ref-1 can be an important target to modulate the level of inflammation and VIII oxidative stress, and vitamin B6 seems modulates several proteins related to cell death. So, this study highlights a new understanding on the role of APE1/Ref-1 on the inflammation and the oxidative stress during inflammation condition

Non-anomalous generalized chiral Schwinger model

Recently, Basseto and Griguolo1 did a perturbative quantization of what they called a generalized chiral Schwinger model. As a consequence of the kind of quantization adopted, some gauge-dependent masses raised in the model. On the other hand, we discussed the possibility of introducing a generalized Wess-Zumino term,2 where such gauge-dependent masses did appear. Here we intend to show that one can construct a non-anomalous version of a model which include that, presented by Basseto and Griguolo as a particular case, by adding to it a generalized Wess-Zumino term, as proposed in Ref. 2. So we conclude that it is possible to construct a gauge-invariant extension of the model quoted in Ref. 1, and this can be done through a Wess-Zumino term of the type proposed in Ref. 2.

Aerosol-cloud interactions studied with a chemistry-climate model

This study aims at a comprehensive understanding of the effects of aerosol-cloud interactions and their effects on cloud properties and climate using the chemistry-climate model EMAC. In this study, CCN activation is regarded as the dominant driver in aerosol-cloud feedback loops in warm clouds. The CCN activation is calculated prognostically using two different cloud droplet nucleation parameterizations, the STN and HYB CDN schemes. Both CDN schemes account for size and chemistry effects on the droplet formation based on the same aerosol properties. The calculation of the solute effect (hygroscopicity) is the main difference between the CDN schemes. The kappa-method is for the first time incorporated into Abdul-Razzak and Ghan activation scheme (ARG) to calculate hygroscopicity and critical supersaturation of aerosols (HYB), and the performance of the modied scheme is compared with the osmotic coefficient model (STN), which is the standard in the ARG scheme. Reference simulations (REF) with the prescribed cloud droplet number concentration have also been carried out in order to understand the effects of aerosol-cloud feedbacks. In addition, since the calculated cloud coverage is an important determinant of cloud radiative effects and is influencing the nucleation process two cloud cover parameterizations (i.e., a relative humidity threshold; RH-CLC and a statistical cloud cover scheme; ST-CLC) have been examined together with the CDN schemes, and their effects on the simulated cloud properties and relevant climate parameters have been investigated. The distinct cloud droplet spectra show strong sensitivity to aerosol composition effects on cloud droplet formation in all particle sizes, especially for the Aitken mode. As Aitken particles are the major component of the total aerosol number concentration and CCN, and are most sensitive to aerosol chemical composition effect (solute effect) on droplet formation, the activation of Aitken particles strongly contribute to total cloud droplet formation and thereby providing different cloud droplet spectra. These different spectra influence cloud structure, cloud properties, and climate, and show regionally varying sensitivity to meteorological and geographical condition as well as the spatiotemporal aerosol properties (i.e., particle size, number, and composition). The changes responding to different CDN schemes are more pronounced at lower altitudes than higher altitudes. Among regions, the subarctic regions show the strongest changes, as the lower surface temperature amplifies the effects of the activated aerosols; in contrast, the Sahara desert, where is an extremely dry area, is less influenced by changes in CCN number concentration. The aerosol-cloud coupling effects have been examined by comparing the prognostic CDN simulations (STN, HYB) with the reference simulation (REF). Most pronounced effects are found in the cloud droplet number concentration, cloud water distribution, and cloud radiative effect. The aerosol-cloud coupling generally increases cloud droplet number concentration; this decreases the efficiency of the formation of weak stratiform precipitation, and increases the cloud water loading. These large-scale changes lead to larger cloud cover and longer cloud lifetime, and contribute to high optical thickness and strong cloud cooling effects. This cools the Earth's surface, increases atmospheric stability, and reduces convective activity. These changes corresponding to aerosol-cloud feedbacks are also differently simulated depending on the cloud cover scheme. The ST-CLC scheme is more sensitive to aerosol-cloud coupling, since this scheme uses a tighter linkage of local dynamics and cloud water distributions in cloud formation process than the RH-CLC scheme. For the calculated total cloud cover, the RH-CLC scheme simulates relatively similar pattern to observations than the ST-CLC scheme does, but the overall properties (e.g., total cloud cover, cloud water content) in the RH simulations are overestimated, particularly over ocean. This is mainly originated from the difference in simulated skewness in each scheme: the RH simulations calculate negatively skewed distributions of cloud cover and relevant cloud water, which is similar to that of the observations, while the ST simulations yield positively skewed distributions resulting in lower mean values than the RH-CLC scheme does. The underestimation of total cloud cover over ocean, particularly over the intertropical convergence zone (ITCZ) relates to systematic defficiency of the prognostic calculation of skewness in the current set-ups of the ST-CLC scheme.rnOverall, the current EMAC model set-ups perform better over continents for all combinations of the cloud droplet nucleation and cloud cover schemes. To consider aerosol-cloud feedbacks, the HYB scheme is a better method for predicting cloud and climate parameters for both cloud cover schemes than the STN scheme. The RH-CLC scheme offers a better simulation of total cloud cover and the relevant parameters with the HYB scheme and single-moment microphysics (REF) than the ST-CLC does, but is not very sensitive to aerosol-cloud interactions.

Stable isotope record, Mg/Ca ratios and age model of St. Stephens Quarry, Alabama

In the largest global cooling event of the Cenozoic Era, between 33.8 and 33.5 Myr ago, warm, high-CO2 conditions gave way to the variable 'icehouse' climates that prevail today. Despite intense study, the history of cooling versus ice-sheet growth and sea-level fall reconstructed from oxygen isotope values in marine sediments at the transition has not been resolved. Here, we analyse oxygen isotopes and Mg/Ca ratios of benthic foraminifera, and integrate the results with the stratigraphic record of sea-level change across the Eocene-Oligocene transition from a continental-shelf site at Saint Stephens Quarry, Alabama. Comparisons with deep-sea (Sites 522 (South Atlantic) and 1218 (Pacific)) d18O and Mg/Ca records enable us to reconstruct temperature, ice-volume and sea-level changes across the climate transition. Our records show that the transition occurred in at least three distinct steps, with an increasing influence of ice volume on the oxygen isotope record as the transition progressed. By the early Oligocene, ice sheets were ~25% larger than present. This growth was associated with a relative sea-level decrease of approximately 105 m, which equates to a 67 m eustatic fall.

Static GPS measurements and elevation model in the hinterland of Neumayer

As part of the CryoSat Cal/Val activities and the pre-site survey for an ice core drilling contributing to the International Partnerships in Ice Core Sciences (IPICS), ground based kinematic GPS measurements were conducted in early 2007 in the vicinity of the German overwintering station Neumayer (8.25° W and 70.65° S). The investigated area comprises the regions of the ice tongues Halvfarryggen and Søråsen, which rise from the Ekströmisen to a maximum of about 760 m surface elevation, and have an areal extent of about 100 km x 50 km each. Available digital elevation models (DEMs) from radar altimetry and the Antarctic Digital Database show elevation differences of up to hundreds of meters in this region, which necessitated an accurate survey of the conditions on-site. An improved DEM of the Ekströmisen surroundings is derived by a combination of highly accurate ground based GPS measurements, satellite derived laser altimetry data (ICESat), airborne radar altimetry (ARA), and radio echo sounding (RES). The DEM presented here achieves a vertical accuracy of about 1.3 m and can be used for improved ice dynamic modeling and mass balance studies.

Static GPS measurements and elevation model in the vicinity of the EDML deep-drilling site

Interpretation of ice-core records requires accurate knowledge of the past and present surface topography and stress-strain fields. The European Project for Ice Coring in Antarctica (EPICA) drilling site (0.0684° E and 75.0025° S, 2891.7 m) in Dronning Maud Land, Antarctica, is located in the immediate vicinity of a transient and splitting ice divide. A digital elevation model is determined from the combination of kinematic GPS measurements with the GLAS12 data sets from the ICESat satellite. Based on a network of stakes, surveyed with static GPS, the velocity field around the EDML drilling site is calculated. The annual mean velocity magnitude of 12 survey points amounts to 0.74 m/a. Flow directions mainly vary according to their distance from the ice divide. Surface strain rates are determined from a pentagon-shaped stake network with one center point, close to the drilling site. The strain field is characterised by along flow compression, lateral dilatation, and vertical layer thinning.

Static GPS measurements in the vicinity of EDML and an elevation model for Dronning Maud Land

The knowledge of ice sheet surface topography and the location of the ice divides are essential for ice dynamic modeling. An improved digital elevation model (DEM) of Dronning Maud Land (DML), Antarctica, is presented in this paper. It is based on ground-based kinematic GPS profiles, airborne radar altimetry, and data of the airborne radio-echo sounding system, as well as spaceborne laser altimetry from NASA's Ice, Cloud and land Elevation Satellite (ICESat). The accuracy of ICESat ice sheet altimetry data in the area of investigation is discussed. The location of the ice divides is derived from aspect calculation of the topography and is verified with several velocity data derived from repeated static GPS measurements.

Age model and elemental data of DSDP Holes 48-401 and 80-549

A growing body of geologic evidence suggests that emplacement of the North Atlantic Igneous Province (NAIP) played a major role in global warming during the early Paleogene as well as in the transient Paleocene-Eocene thermal maximum (PETM) event. A ~5 million year record of major and trace element abundances spanning 56 to 51 Ma at Deep Sea Drilling Project Sites 401 and 549 confirms that the majority of NAIP volcanism occurred as subaerial flows. Thus the trace element records provide constraints on the nature and scope of the environmental impact of the NAIP during the late Paleocene-early Eocene interval. Subaerial volcanism would have injected mantle CO2 directly into the atmosphere, resulting in a more immediate increase in atmospheric greenhouse gas abundances than CO2 input through submarine volcanism. The lack of significant hydrothermalism contradicts recently proposed mechanisms for thermally destabilizing methane hydrate reservoirs during the PETM. Any connection between NAIP volcanism and PETM warming had to occur through the atmosphere.

Pore water geochemistry of arctic deep sea sediments measured at station MSM16/2_809-1 (REF, Reference)

Pore water and turnover rates were determined for surface sediment cores obtained in 2009 and 2010. The pore water was extracted with Rhizons (Rhizon CSS: length 5 cm, pore diameter 0.15 µm; Rhizosphere Research Products, Wageningen, Netherlands) in 1 cm-resolution and immediately fixed in 5% zinc acetate (ZnAc) solution for sulfate, and sulfide analyses. The samples were diluted, filtered and the concentrations measured with non-suppressed anion exchange chromatography (Waters IC-Pak anion exchange column, waters 430 conductivity detector). The total sulfide concentrations (H2S + HS- + S**2-) were determined using the diamine complexation method (doi:10.4319/lo.1969.14.3.0454). Samples for dissolved inorganic carbon (DIC) and alkalinity measurements were preserved by adding 2 µl saturated mercury chloride (HgCl2) solution and stored headspace-free in gas-tight glass vials. DIC and alkalinity were measured using the flow injection method (detector VWR scientific model 1054) (doi:10.4319/lo.1992.37.5.1113). Dissolved sulfide was eliminated prior to the DIC measurement by adding 0.5 M molybdate solution (doi:10.4319/lo.1995.40.5.1011). Nutrient subsamples (10 - 15 ml) were stored at - 20 °C prior to concentration measurements with a Skalar Continuous-Flow Analyzer (doi:10.1002/9783527613984).

Applying model-driven engineering to the development of Rich Internet Applications for Business Intelligence

Business Intelligence (BI) applications have been gradually ported to the Web in search of a global platform for the consumption and publication of data and services. On the Internet, apart from techniques for data/knowledge management, BI Web applications need interfaces with a high level of interoperability (similar to the traditional desktop interfaces) for the visualisation of data/knowledge. In some cases, this has been provided by Rich Internet Applications (RIA). The development of these BI RIAs is a process traditionally performed manually and, given the complexity of the final application, it is a process which might be prone to errors. The application of model-driven engineering techniques can reduce the cost of development and maintenance (in terms of time and resources) of these applications, as they demonstrated by other types of Web applications. In the light of these issues, the paper introduces the Sm4RIA-B methodology, i.e., a model-driven methodology for the development of RIA as BI Web applications. In order to overcome the limitations of RIA regarding knowledge management from the Web, this paper also presents a new RIA platform for BI, called RI@BI, which extends the functionalities of traditional RIAs by means of Semantic Web technologies and B2B techniques. Finally, we evaluate the whole approach on a case study—the development of a social network site for an enterprise project manager.

Burton Tower model

Photographic print of architectural model