Annotation of Case C-43/93, Raymond Vander Elst v Office des Migrations Internationales, ECR I-3803

Freedom to provide services - Nationals of a non-member country - Posted Workers

Raymond Geuss’ radicalization of realism in political theory

Raymond Geuss has been viewed as one of the figureheads of the recent debates about realism in political theory. This interpretation, however, depends on a truncated understanding of his work of the past 30 years. I will offer the first sustained engagement with this work (in English and German) which allows understanding his realism as a project for reorienting political theory, particularly the relationship between political theory and politics. I interpret this reorientation as a radicalization of realismin political theory through the combination of the emphasis on the critical purpose of political theory and the provision of practical, contextual orientation. Their compatibility depends on Geuss’ understanding of criticism as negative, of power as ‘detoxified’ and of the critical purchase of political theory as based on the diagnostic engagement with its context. This radicalization particularly challenges the understanding of how political theory relates to its political context.

A natureza do poder em Raymond Aron : ontologia e epistemologia da Ordem Internacional

Tese de Doutoramento em Relações Internacionais, especialidade de História e Teoria das Relações Internacionais

Subgroup-specific structural variation across 1,000 medulloblastoma genomes.

Medulloblastoma, the most common malignant paediatric brain tumour, is currently treated with nonspecific cytotoxic therapies including surgery, whole-brain radiation, and aggressive chemotherapy. As medulloblastoma exhibits marked intertumoural heterogeneity, with at least four distinct molecular variants, previous attempts to identify targets for therapy have been underpowered because of small samples sizes. Here we report somatic copy number aberrations (SCNAs) in 1,087 unique medulloblastomas. SCNAs are common in medulloblastoma, and are predominantly subgroup-enriched. The most common region of focal copy number gain is a tandem duplication of SNCAIP, a gene associated with Parkinson's disease, which is exquisitely restricted to Group 4α. Recurrent translocations of PVT1, including PVT1-MYC and PVT1-NDRG1, that arise through chromothripsis are restricted to Group 3. Numerous targetable SCNAs, including recurrent events targeting TGF-β signalling in Group 3, and NF-κB signalling in Group 4, suggest future avenues for rational, targeted therapy.

Raymond Gommier, 3ème [du championnat de France professionnel, golf de la Boulie, Versailles, le 11/5/20] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 59242

Arrêt du grand conseil qui ordonne l'exécution des lettres en forme de provision de l'état et privilège d'opérateur du roi, suivant la cour, et de ses conseils, accordées au Sr Pierre-Raymond-Vaconssain, marchand épicier droguiste à Paris, le 1er septembre 1750, en la prévôté de l'hôtel et grande prévôté de France

[Acte. 1750-12-09. Paris]