Atividade tripanocida de Piper arboreum e Piper tuberculatum (Piperaceae)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Radical Scavenging Capacity of Piper arboreum and Piper tuberculatum (Piperaceae)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Biological activities of constituents from Psychotria spectabilis

In a biological and phytochemical study on the leaves of Psychotria spectabilis Steyerm., seven compounds were isolated and identified from the CHCl3/MeOH (2:1, v/v) and MeOH extracts. Among the isolates were two diterpenes, solidagenone and deoxysolidagenone; three coumarins, coumarin, umbelliferone, and psoralene; and two flavonols, quercetin and quercetrin. Biological evaluations showed that diterpenes and coumarins exhibited antifungal activity against the filamentous fungi Cladosporium cladosporioides (Fresen) de Vries and C sphaerospermum Penzig. Solidagenone and psoralene also displayed selective cytotoxic activity against Rad 52Y mutant yeast strain of Saccharomyces cerevisiae. In this paper, the isolation, structure elucidation, and bioactivity results of these compounds are reported.

Butanolides as a common feature of Iryanthera lancifolia and Virola surinamensis

A comparative phytochemical study between pericarps of Iryanthera lancifolia and Virola surinamensis showed that the first one contains a new pair of epimeric 2-alkenyl-gamma-lactones, besides an aryltetralinic lignan and one tocotrienol, while the second species contains the lignans, galgravin and veraguensin, seven juruenolides: juruenolides C, D, F, G and epi-juruenolides D, F, G, together with three pairs of epimeric aliphatic 2-alkenyl-gamma-lactones. Juruenolide F, epi-juruenolides D, F, G and the 2-alkenyl-gamma-lactones are new natural compounds. (C) 1998 Elsevier B.V. Ltd. All rights reserved.

Estudo farmacognóstico do caule e raízes de Microgramma squamulosa (Kaulf.) Sota (Polypodiaceae)

Pharmacognostic and phytochemical study of the stem and root,,of Microgramma squamulosa (Kaulf.) Sota. Erva silvina, or Microgramma squamulosa (Kaulf.), Sota belongs to the family Polylodiaceae and is traditionally used as an antiulcer agent. Previous assays showed results that confirm the antiulcer action of the ethanolic extract and some fractions of the stem of M squamulosa and results showing no significant toxicity in the acute model, both made in rats Due to the significant results obtained in this previous work, it becomes important to furnish tools to identify the vegetal drug. The species is' an epiphyte that bears lanceolate scales totally covering the long-creeping brown-colored stem. Adventicious roots can be seen in the abaxial portion of, the-stem, while the leaves appear in the adaxial portion. Elements which contribute to the histological identification are: peltate lanceolate -haired scales, sclereids, meristeles (amphicribal bundles) and scalariform the roots. Phytochemical screening, and TLC tracheids in the stem; strip hairs and sclereids in analysis showed the presence of flavonoids and tannins which may be related to the anti,ulcer the plant as well as the characterization of activity. Results shown may help the identification of the fragmented vegetal drug and if it is presented as powder or as extract.

Evaluation of the toxicity of Virola sebifera crude extracts, fractions and isolated compounds on the nest of leaf-cutting ants

The phytochemical study of Virola sebifera leaves led to the isolation of three lignans: (+)-sesamin, (-)-hinokinin, and (-)-kusunokinin and three flavonoids: quercetin-3-O - L-rhamnoside, quercetin-3-O - D-glucoside, and quercetin-3-methoxy-7-O - D-glucoside by using techniques as high-speed counter-current chromatography and high-performance liquid chromatography. The crude extracts, fractions, and isolated compounds were evaluated for their insecticidal and fungicidal potential against Atta sexdens rubropilosa and its symbiotic fungus Leucoagaricus gongylophorus. The bioassay results showed a high insecticidal activity for the methanol crude extract of the leaves of V. sebifera and its n-hexane, dichloromethane and ethyl acetate fractions. The fungicidal bioassay revealed high toxicity of the lignans against L. gongylophorus. © 2012 Keylla Utherdyany Bicalho et al.

7-Hydroxycassine: A new 2,6-dialkylpiperidin-3-ol alkaloid and other constituents isolated from flowers and fruits of senna spectabilis (Fabaceae)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Cordia verbenacea DC: perfil morfo-anatômico, histoquímico, farmacognóstico e avaliação da atividade anti-candida do extrato hidroetanólico e suas frações

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo químico e atividade mutagênica e antiradicalar e Paepalanthus chiquitensis Herzog (ERIOCAULACEAE)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Constituintes químicos e atividades antioxidante e alelopática de Bauhinia holophylla (Bong.) Steud

Pós-graduação em Ciências Biológicas (Botânica) - IBB

Estudo químico e atividade biológica de Garcinia xanthochymus (Clusiaceae)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo fitoquímico da fração AcOEt do extrato etanólico das folhas de Arrabidaea brachypoda (DC) Bureau - Bignoniaceae e atividades antioxidante e inibitória da enzima mieloperoxidase das substancias isoladas

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Estudo fitoquímico e busca de substâncias bioativas de Chrysophyllum flexuosum (Sapotaceae)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo fitoquímico dos frutos de Senna spectabilis e análise comparativa do perfil alcaloídico de S. spectabilis e Cassia leptophylla

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Investigação fitoquímica e avaliação da atividade antioxidante das folhas e frutos de Eugenia jambolana Lam. (Myrtaceae)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)