Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990–2013: Quantifying the epidemiological transition

Background The Global Burden of Disease Study 2013 (GBD 2013) aims to bring together all available epidemiological data using a coherent measurement framework, standardised estimation methods, and transparent data sources to enable comparisons of health loss over time and across causes, age–sex groups, and countries. The GBD can be used to generate summary measures such as disability-adjusted life-years (DALYs) and healthy life expectancy (HALE) that make possible comparative assessments of broad epidemiological patterns across countries and time. These summary measures can also be used to quantify the component of variation in epidemiology that is related to sociodemographic development. Methods We used the published GBD 2013 data for age-specific mortality, years of life lost due to premature mortality (YLLs), and years lived with disability (YLDs) to calculate DALYs and HALE for 1990, 1995, 2000, 2005, 2010, and 2013 for 188 countries. We calculated HALE using the Sullivan method; 95% uncertainty intervals (UIs) represent uncertainty in age-specific death rates and YLDs per person for each country, age, sex, and year. We estimated DALYs for 306 causes for each country as the sum of YLLs and YLDs; 95% UIs represent uncertainty in YLL and YLD rates. We quantified patterns of the epidemiological transition with a composite indicator of sociodemographic status, which we constructed from income per person, average years of schooling after age 15 years, and the total fertility rate and mean age of the population. We applied hierarchical regression to DALY rates by cause across countries to decompose variance related to the sociodemographic status variable, country, and time. Findings Worldwide, from 1990 to 2013, life expectancy at birth rose by 6·2 years (95% UI 5·6–6·6), from 65·3 years (65·0–65·6) in 1990 to 71·5 years (71·0–71·9) in 2013, HALE at birth rose by 5·4 years (4·9–5·8), from 56·9 years (54·5–59·1) to 62·3 years (59·7–64·8), total DALYs fell by 3·6% (0·3–7·4), and age-standardised DALY rates per 100 000 people fell by 26·7% (24·6–29·1). For communicable, maternal, neonatal, and nutritional disorders, global DALY numbers, crude rates, and age-standardised rates have all declined between 1990 and 2013, whereas for non–communicable diseases, global DALYs have been increasing, DALY rates have remained nearly constant, and age-standardised DALY rates declined during the same period. From 2005 to 2013, the number of DALYs increased for most specific non-communicable diseases, including cardiovascular diseases and neoplasms, in addition to dengue, food-borne trematodes, and leishmaniasis; DALYs decreased for nearly all other causes. By 2013, the five leading causes of DALYs were ischaemic heart disease, lower respiratory infections, cerebrovascular disease, low back and neck pain, and road injuries. Sociodemographic status explained more than 50% of the variance between countries and over time for diarrhoea, lower respiratory infections, and other common infectious diseases; maternal disorders; neonatal disorders; nutritional deficiencies; other communicable, maternal, neonatal, and nutritional diseases; musculoskeletal disorders; and other non-communicable diseases. However, sociodemographic status explained less than 10% of the variance in DALY rates for cardiovascular diseases; chronic respiratory diseases; cirrhosis; diabetes, urogenital, blood, and endocrine diseases; unintentional injuries; and self-harm and interpersonal violence. Predictably, increased sociodemographic status was associated with a shift in burden from YLLs to YLDs, driven by declines in YLLs and increases in YLDs from musculoskeletal disorders, neurological disorders, and mental and substance use disorders. In most country-specific estimates, the increase in life expectancy was greater than that in HALE. Leading causes of DALYs are highly variable across countries. Interpretation Global health is improving. Population growth and ageing have driven up numbers of DALYs, but crude rates have remained relatively constant, showing that progress in health does not mean fewer demands on health systems. The notion of an epidemiological transition—in which increasing sociodemographic status brings structured change in disease burden—is useful, but there is tremendous variation in burden of disease that is not associated with sociodemographic status. This further underscores the need for country-specific assessments of DALYs and HALE to appropriately inform health policy decisions and attendant actions.

Reproduction of oil painting portrait of Ernestine Salomonsen nee Philip Portraits Women

Digital Image

Philip Cowen papers undated, 1873-1935

Contains primarily correspondence and published material in English, German and Russian relating to anti-Semitism in Russia and Roumania, the Russian passport question, loans from Jewish bankers to the Russian government and immigration from Eastern Europe, especially Russia, to the United States. Includes also correspondence concerning Jewish welfare institutions and agricultural colonies in the United States and the National Farm School in Doylestown, Pa. Also contains correspondence relating to and drafts of articles for the American Hebrew, particularly the Emma Lazarus memorial number, and correspondence relating to the publication of the Jewish encyclopedia and to survey on anti-Semitism conducted in 1890, as well as information on the Jews in China and material relating to Count Arthur Cherep-Spiridovich.

Philip Slomovitz papers, undated, 1933-1966.

Contains correspondence as editor of the Detroit Jewish chronicle and of The Jewish news. Of special interest is the correspondence with members of the U.S. Congress relating to aid to Israel, material relating to the boycott of Viceroy cigarettes, the question of the Jewish descent of Franklin Delano Roosevelt, and the dictionary definition of "Jew."

Philip Slomovitz South End collection 1969-1974

Contains 1969 and 1971-73 issues of The South End, Wayne State University student paper, as well as correspondence, public statements, petitions and a tape-recording relating to controversies generated by the printing of alleged anti-Zionist/anti-Semitic articles in the newspaper. The correspondence consists for the most part of an exchange of letters between university officials, Jewish community leaders and Leonard N. Simons, a Detroit advertising executive, during the 1969 controversy, and correspondence with Philip Slomovitz, editor of the Detroit Jewish news, in 1972-73. The tape recording is of a February 2, 1969 interview with John Watson, editor of the South end.

Aaron Lopez papers, undated, 1752-1794, 1846, 1852, 1953.

Contains approximately 6800 manuscripts arranged chronologically by year for years 1752-1794. Approximately 100 are letters received or written by Lopez, his partner and father-in-law, Jacob Rodriguez Rivera, members of his family and company, and commercial agents pertaining to business activities and sailing orders for the captains of various ships. Several also refer to personal matters and acquaintances, including a series of six letters from Silas Cooke of White Hall (Middletown), R.I., to Aaron Lopez, asking his aid in returning a run-away slave (1776). The great majority of the collection consists of account records, bills of sale, orders, shipping agreements, lists of sailors on the various ships, repair records and cargo invoices. Of particular interest are a receipt for payment of a half-year's subscription to the "tzedakah" of Congregation Nefutzei Israel, Newport (1755) and several documents that reveal Lopez as a supplier of kosher meat and other religious articles to people in various parts of the colonies, Surinam, and Jamaica. Also included in this group are copies of sailing lists, documents pertaining to Lopez's naturalization which shed light upon the status of a Jew applying for citizenship in Massachusetts and a check to Lopez from the United States government for a loan made during the Revolutionary War (1779).

Letter regarding prohibition of Philip J. Joachimsen from receiving mitzvah

Digital image

Christianity and Christian Identity in the Gospel of Philip (NHC II,3)

Previous scholarship has often maintained that the Gospel of Philip is a collection of Valentinian teachings. In the present study, however, the text is read as a whole and placed into a broader context by searching for parallels from other early Christian texts. Although the Valentinian Christian identity of the Gospel of Philip is not questioned, it is read alongside those texts traditionally labelled as "mainstream Christian". It is obvious from the account of Irenaeus that the boundaries between the Valentinians and other Christians were not as clear or fixed as he probably would have hoped. This study analyzes the Valentinian Christian Gospel of Philip from two points of view: how the text constructs the Christian identity and what kind of Christianity it exemplifies. Firstly, it is observed how the author of the Gospel of Philip places himself and his Christian readers among the early Christianities of the period by emphasizing the common history and Christian features but building especially on particular texts and traditions. Secondly, it is noted how the Christian nature of an individual develops according to the Gospel of Philip. The identity of an individual is built and strengthened through rituals, experiences and teaching. Thirdly, the categorizations, attributes, beliefs and behaviour associated on the one hand with the "insiders", the true Christians, and, on the other, with outsiders in the Gospel of Philip, are analyzed using social identity theory the insiders and outsiders are described through stereotyping in the text. Overall, the study implies that the Gospel of Philip strongly emphasizes spiritual progress and transformation. Rather than depicting the Valentinians as the perfect Christians, it underlines their need for constant change and improvement. Although the author seeks to clearly distinguish the insiders from the outsiders, the boundaries of the categories are in fact fluid in the Gospel of Philip. Outsiders can become insiders and the insiders are also in danger of falling out again.

Edge of Danger: electric light and the negotiation of public and private domestic space in Philip Johnson's Glass and Guest House

In the first half of the twentieth century the dematerializing of boundaries between enclosure and exposure problematized traditional expectations of the domestic environment. At the same time, as a space of escalating technological control, the modern domestic interior also offered new potential to redefine the meaning and means of habitation. The inherent tension between these opposing forces is particularly evident in the introduction of new electric lighting technology and applications into the modern domestic interior in the mid-twentieth century. Addressing this nexus of technology and domestic psychology, this article examines the critical role of electric lighting in regulating and framing both the public and private occupation of Philip Johnson's New Canaan estate. Exploring the dialectically paired transparent Glass House and opaque Guest House, this study illustrates how Johnson employed electric light to negotiate the visual environment of the estate as well as to help sustain a highly aestheticized domestic lifestyle. Contextualized within the existing literature, this analysis provides a more nuanced understanding of the New Canaan estate as an expression of Johnson's interests as a designer as well as a subversion of traditional suburban conventions.

The Edge of Danger: artificial lighting and the dialectics of domestic occupation in Philip Johnson's Glass and Guest Houses

In the first half of the twentieth century the dematerializing of boundaries between enclosure and exposure problematized traditional acts of “occupation” and understandings of the domestic environment. As a space of escalating technological control, the modern domestic interior offered new potential to re-define the meaning and means of habitation. This shift is clearly expressed in the transformation of electric lighting technology and applications for the modern interior in the mid-twentieth century. Addressing these issues, this paper examines the critical role of electric lighting in regulating and framing both the public and private occupation of Philip Johnson’s New Canaan estate. Exploring the dialectically paired transparent Glass House and opaque Guest House (both 1949), this study illustrates how Johnson employed artificial light to control the visual environment of the estate as well as to aestheticize the performance of domestic space. Looking closely at the use of artificial light to create emotive effects as well as to intensify the experience of occupation, this revisiting of the iconic Glass House and lesser-known Guest House provides a more complex understanding of Johnson’s work and the means with which he inhabited his own architecture. Calling attention to the importance of Johnson serving as both architect and client, and his particular interest in exploring the new potential of architectural lighting in this period, this paper investigates Johnson’s use of electric light to support architectural narratives, maintain visual order and control, and to suit the nuanced desires of domestic occupation.

Emergenssi tieteessä ja teologiassa : Huomioita Philip Claytonin emergenssiteoriasta

Tässä työssä tarkastellaan emergenssiä luonnontieteellisenä, metafyysisenä ja teologisena käsitteenä, ja erityisesti Philip Claytonin emergenssiteoriaa. Tutkimuskohteena on Philip Claytonin kirja Mind and Emergence From Quantum to Consciousness ja tutkimusmetodina käsitteellinen analyysi. Kun emergenssiä tarkastellaan metafyysisenä teoriana, se on mahdollista nähdä fysikalismille ja dualismille vaihtoehtoisena filosofisena katsantokantana todellisuuteen. Fysikalismi on havaittavaa todellisuutta koskeva näkemys, jonka mukaan kaikki ilmiöt ovat lopulta palautettavissa fysiikkaan ja selitettävissä fysiikan käsittein. Dualismi taas on näkemys, että erityisesti ihmisen mieli ja tietoisuus ovat jotain fysikaaliseen maailmaan nähden täysin erilaista ja siitä riippumatonta. Emergenssiteoriassa maailman nähdään kehittyvänä kokonaisuutena, jossa kompleksisuuden kasvun myötä syntyy jatkuvasti uusia ominaisuuksia. Nämä ominaisuudet eivät ole palautettavissa niihin rakenteisiin, joiden pohjalta ne ovat syntyneet. Niiden syntymistä ei ole mahdollista luonnontieteellisin tai muinkaan menetelmin ennakoida. Emergenssin heikossa muodossa tämä ennakoimattomuus on vain episteeminen, tiedon mahdollisuuksiin liittyvä rajoitus, ja kausaalisia vaikutuksia esiintyy ainoastaan fysikaalisten objektien tasolla. Metafyysinen teoria edellyttää kuitenkin vahvaa emergenssiä, jossa syntyvillä ominaisuuksilla on fysikaalisesta perustastaan riippumatonta kausaalista vaikutusta. Tätä kutsutaan alaspäin -kausaalisuudeksi. Käsitys todellisuudesta on monistinen ja holistinen. Kaikki olemassa oleva on kehittynyt samasta aineksesta, mutta ei ole palautettavissa siihen. Maailmassa on ontologisesti toisistaan poikkeavia todellisuuden tasoja. Todellisuus on enemmän kuin osiensa summa. Emergenssille on tarjottu myös teologisia sovelluksia. Kun fysikalismissa uskonnolliselle uskolle ei jää tilaa ja dualismi on luonnontieteen näkökulmasta ongelmallinen, emergenssistä on etsitty filosofista viitekehystä, jossa luonnontiede ja uskonto olisivat sovitettavissa yhteen. Ensimmäisessä luvussa käsitellään fysikalismia ja dualismia ja erityisesti filosofista ja luonnontieteellistä kritiikkiä, jota niitä vastaan voidaan esittää. Toisessa luvussa tarkastellaan erilaisia mahdollisuuksia määritellä emergenssin käsite ja esitellään erityisesti Philip Claytonin käsityksiä heikosta ja vahvasta emergenssistä, emergenssistä luonnontieteissä sekä ihmismielestä fysikaaliseen maailmaan nähden emergenttinä ilmiönä. Emergenssi mainitaan monien sellaisten ilmiöiden yhteydessä, joita on pyritty tutkimaan kaaosteorian ja kompleksisuuden tutkimuksen keinoin. Työn kolmannessa luvussa pyritään antamaan kuva emergenssin suhteesta näihin teorioihin ja ylipäätään moderniin fysiikkaan. Philip Clayton on luonut emergenssiteorian pohjalta myös teologisen teorian, jossa käsitys Jumalasta luojana ja Jumalan vaikutus maailmassa pyritään sovittamaan yhteen emergentin todellisuuskäsityksen kanssa. Tätä teologista teoriaa esitellään ja arvioidaan työn neljännessä luvussa.

Philip公式确定吸渗率时间尺度研究

选用直径5 cm和10 cm的盘式吸渗仪,对杨凌土(粘土)和神木砂黄土(砂壤土)两种质地的土壤在1 cm、3 cm6、cm9、cm和12 cm水头5种负压下进行了室内盘式吸渗仪三维吸渗实验,选取Vandervaere公式作为参考模型,对Philip公式确定吸渗率的时间尺度选取进行了分析。结果表明,对两种质地的土壤,在相同盘径下,随着负压的降低,吸渗率随之减小;在相同负压下,盘径越小,吸渗率越大;质地较砂的砂黄土吸渗率明显大于质地较粘的土的吸渗率。从相对误差来看,两种质地土壤吸渗率均被高估;在同一盘径下,随着负压的减小,误差值逐渐降低;即在选取的时间范围内,负压越低,计算吸渗率的准确性越高。对土而言,5 cm盘径下-12 cm水头1、0 cm盘径下-9 cm水头和-12 cm水头时确定吸渗率的适宜时间分别为30~40 s和40~50 s;其余确定吸渗率的适宜时间均应小于30 s;对砂黄土而言,10 cm盘径下-9 cm水头和-12 cm水头时确定吸渗率的适宜时间分别为30~40 s和40~50 s,其余确定吸渗率的适宜时间也均应小于30 s。对于质地较砂的土壤推荐使用大盘径进行盘式吸渗仪实验。

[Book review] Philip E. Agre and Stanley J. Rosenschein (eds), Computational Theories of Interaction and Agency

Review of: Philip E. Agre and Stanley J. Rosenschein (eds), Computational Theories of Interaction and Agency, MIT Press (1996), ISBN: 978-0262510905

[Performance review] Philip Glass, Galileo Galilei

Review of the European premiere of the opera Galileo Galilei by Philip Glass performed at The Goodman Theatre, Barbican Centre, London in November 2002.