Expectativas del paciente y su correlación con la escala de Constant y el cuestionario de calidad de vida SF-36

El objetivo del estudio es la evaluación subjetiva del hombro a través del análisis de expectativas en el dolor, la funcionalidad, las actividades de la vida diaria y la fuerza que el paciente espera obtener tras el tratamiento de la patología del hombro, y posteriormente, evaluar la correlación de estos datos obtenidos con los resultados en la escala de Constant y en el SF- 36. La hipótesis que nos planteamos fue que las expectativas del paciente son independientes del estado funcional del hombro y de la percepción de la calidad de vida.

Validation of the Mini Nutritional Assessment short-form (MNA-SF): a practical tool for identification of nutritional status.

OBJECTIVE: To validate a revision of the Mini Nutritional Assessment short-form (MNA(R)-SF) against the full MNA, a standard tool for nutritional evaluation. METHODS: A literature search identified studies that used the MNA for nutritional screening in geriatric patients. The contacted authors submitted original datasets that were merged into a single database. Various combinations of the questions on the current MNA-SF were tested using this database through combination analysis and ROC based derivation of classification thresholds. RESULTS: Twenty-seven datasets (n=6257 participants) were initially processed from which twelve were used in the current analysis on a sample of 2032 study participants (mean age 82.3y) with complete information on all MNA items. The original MNA-SF was a combination of six questions from the full MNA. A revised MNA-SF included calf circumference (CC) substituted for BMI performed equally well. A revised three-category scoring classification for this revised MNA-SF, using BMI and/or CC, had good sensitivity compared to the full MNA. CONCLUSION: The newly revised MNA-SF is a valid nutritional screening tool applicable to geriatric health care professionals with the option of using CC when BMI cannot be calculated. This revised MNA-SF increases the applicability of this rapid screening tool in clinical practice through the inclusion of a "malnourished" category.

Mapeamento pedológico digital da folha Botucatu (SF-22-Z-B-VI-3): treinamento de dados em mapa tradicional e validação de campo

O mapeamento digital de solos permite prever padrões de ocorrência de solos com base em áreas de referência e no uso de técnicas de mineração de dados para modelar associações solo-paisagem. Os objetivos deste trabalho foram produzir um mapa pedológico digital por meio de técnicas de mineração de dados aplicadas a variáveis geomorfométricas e de geologia, com base em áreas de referência; e testar a confiabilidade desse mapa por meio de validação em campo com diferentes sistemas de amostragem. O mapeamento foi realizado na folha Botucatu (SF-22-Z-B-VI-3), utilizando-se as folhas 1:50.000, Dois Córregos e São Pedro, como áreas de referência. Variáveis descritoras do relevo e de geologia associadas às unidades de mapeamento pedológico das áreas de referência compuseram a matriz de dados de treinamento. A matriz foi analisada pelo algoritmo PART de árvore de decisão, do aplicativo Weka (Waikato Environment for Knowledge Analysis), que cria regras de classificação. Essas regras foram aplicadas aos dados geomorfométricos e geológicos da folha Botucatu, para predição de unidades de mapeamento pedológico. A validação de campo dos mapas digitais deu-se por meio de amostragem por transectos em uma unidade de mapeamento da folha São Pedro e de forma aleatório-estratificada na folha Botucatu. A avaliação da unidade de mapeamento na folha São Pedro verificou confiabilidade, respectivamente, de 83 e 66 %, para os mapas pedológicos digital e tradicional com legenda simplificada. Apesar de terem sido geradas regras para todas as unidades de mapeamento pedológico das áreas de treinamento, nem todas as unidades de mapeamento foram preditas na folha Botucatu, o que resultou das diferenças de relevo e geologia entre as áreas de treinamento e de mapeamento. A validação de campo do mapa digital da folha Botucatu verificou exatidão global de 52 %, compatível com levantamentos em nível de reconhecimento de baixa intensidade, e kappa de 0,41, indicando qualidade Boa. Unidades de mapeamento mais extensas geraram mais regras, resultando melhor reprodução dos padrões solo-relevo na área a ser mapeada. A validação por transectos na folha São Pedro indicou compatibilidade do mapa digital com o nível de reconhecimento de alta intensidade e compatibilidade do mapa tradicional, após simplificação de sua legenda, com o nível de reconhecimento de baixa intensidade. O treinamento do algoritmo em mapas e não em observações pontuais reduziu em 14 % a exatidão do mapa pedológico digital da folha Botucatu. A amostragem aleatório-estratificada pelo hipercubo latino é apropriada a mapeamentos com extensa base de dados, o que permite avaliar o mapa como um todo, tornando os trabalhos de campo mais eficientes. A amostragem em transectos é compatível com a avaliação da pureza de unidades de mapeamento individualmente, não necessitando de base de dados detalhada e permitindo estudos de associações solo-paisagem em pedossequências.

SF 2088 Convenience Fees Analysis and Recommendations, November 16, 2011

As an expansion of SF2088, the Department of Administrative Services-Information Technology Enterprise (DAS-ITE) was asked to further analyze the potential costs and savings if the current practice of charging credit card and overhead fees (“value-added fees”) were to be eliminated. Value-added fees reflect the costs an agency incurs while providing online services, and those costs will always exist.. DAS-ITE researched these costs and identified ways of making the associated fees less burdensome to the citizens of Iowa. The three alternatives provide different ways in which agencies can recover those costs; they could be borne by either an annual appropriation or adjustment of the online service “price” to include the fees within the cost of the online transaction. An additional alternative is presented to leave the current value-added fee practices in place. Recognition must also be made of the fact that traditional forms of conducting business with the State of Iowa, face-to-face and paper-based transactions, are inherently more costly. These delivery channels are effectively subsidized by the agency as a “cost of doing business” and the associated expense of the transactions is not passed on to the customer.

Report Pursuant to SF 2336: An Act Relating to Appropriations for Health and Human Services

The department shall develop recommendations for an implementation schedule, including funding projections, for the substitute decision maker program created pursuant to chapter 231E, and shall submit the recommendations to the individuals identified in this Act for submission of reports by December 15, 2012.

Validation et normes du SF-36 dans la population du canton de Vaud

[Table des matières] 1. Patients et méthodes. 1.1. Enquête dans la population générale : population, modalités d'envoi, taux de réponse. 1.2. Questionnaire SF-36 et questionnaire Medical Outcome Study (MOS) : PF physical functioning = activité physique (fonctionnement) ; RP role physical = limitations (du rôle) liées à la santé physique ; BP bodily pain = douleur physique ; GH General Health = santé générale ; VT vitality = vitalité (énergie/fatigue) ; SF social functioning = fonctionnement ou bien-être social ; RE role éemotional = limitations (du rôle) liées à la santé mentale ; MH mental health = santé mentale ; CF cognitive functioning = fonctionnement cognitif (dimension absente du SF-36 classique) ; HT eported health transition = modification perçue de l'état de santé ("dimension" annexe, = item 2 ou Q2). 1.3. Analyse : calcul des scores du SF-36 et du SF-36 + CF, cohérence des réponses, fiabilité de l'instrument, validité. 1.4. Analyse statistique. 2. Résultats commentés de l'enquête dans la population générale. 2.1. Fréquence des non-réponses par item et par question. 2.2. Cohérence des réponses. 2.3. Scores d'état de santé par dimension : description et comparaison avec une population américaine, comparaison des scores vaudois et genevois. 2.4. Existe-t-il une concentration des bons et des mauvais scores chez les mêmes répondants ? 2.5. Fiabilité. 2.6. Validité : validité convergente et discriminante, analyse factorielle, validation en fonction de variables externes. 3. Discussion. 3.1. Evaluation du questionnaire. 3.2. Mesure de la qualité de vie liée à l'état de santé perçu dans la population générale. 3.3. Adjonction de la dimension "fonctionnement cognitif". 3.4. Conclusions et recommandations.

MOS-SF-36 in evaluating health-related quality of life in alcohol-dependent patients.

Health-related quality of life (HRQoL) was evaluated in a sample of alcohol-dependent patients with the 36-item Medical Outcome Study Short-Form Health Survey (MOS-SF-36). The instrument was administered to 147 patients (77% males), aged 26-78, with a DSM-III-R diagnosis of alcohol dependence. The Hamilton Depression Scale (HDS), the Severity of Alcohol Dependence Questionnaire (SADQ), and the Addiction Severity Index (ASI) were also administered to the first 100 patients included in the study. The reliability and validity of the MOS-SF-36 were evaluated. Test-retest intraclass coefficients for a 10-day interval were in the range .65 to .79, whereas the Cronbach alpha coefficient indicated good internal consistency (range .70 to .89). Compared to scores observed in the general population, MOS-SF-36 scores for alcohol-dependent patients were relatively low (indicating worse perception of HRQoL), especially in the psychological and role dimensions (range 52/100 to 55/100), but were closer to populational values in the physical and functional dimensions (range 61/100 to 75/100)). The highest correlation between MOS-SF-36 dimensions and HDS was found in the MOS-SF-36 "mental health" dimension (r=-.56, p < .001); this dimension was also correlated highly with the psychiatric dimension of the ASI (r=-.73, p < .001). The eight dimensions of the MOS-SF-36 were 21% to 127% lower in patients with HDS greater than or equal to 16 (major depression) compared to those with HDS less than or equal to 7 (absence of depression). The MOS-SF-36 dimensions were 10% to 141% lower in patients with high "ASI alcohol" scores, indicating worse HRQoL profiles with a higher severity of alcohol dependence. The MOS-SF-36 presents good criteria for reliability and validity in alcohol-dependent patients. The results suggested that alcohol-dependent patients perceived their problems more as psychological than physical. The severity of alcohol dependence and depression seemed to influence the perception of HRQoL negatively.

Spelar kön någon roll när man räddar världen? : kvinnor, kvinnligheter och messiasmyter i SF-film

Studien grundar sig på tanken att populärkulturen och dess uttrycksformer är viktiga att analysera närmare även när det gäller en förståelse av religion i dagens värld. Populärkulturen kan antas både spegla och påverka oss. Detta sker naturligtvis inte på ett enkelt sätt, men populärkulturen kan ändå anses vara med och forma hur vi ser på världen omkring oss och på fenomen som t.ex. religion och könsroller. Den genre Sjö valt att rikta in sig på, science fiction, är vald med tanke på hur denna genre tagit sig an både frågor om religion och genus och hur den även blir av betydelse för analyser av dagens värld. Studien riktar i första hand in sig på forskning kring frälsartemat i populärkulturen. Det delvis nya som tillförs forskningen är ett genusperspektiv. Istället för att rikta in sig på de oftast manliga messiasgestalterna ser studien således till den kvinnliga närvaron i berättelserna. För det första analyseras kvinnliga karaktärer i rollerna som kärleksobjekt och mödrar. Centrala frågor som tas upp i denna del av avhandlingen är de kvinnliga karaktärernas roll i förhållande till manliga messiasgestalter och messiasmyter i materialet. Andra frågor som behandlas är de kvinnliga karaktärernas tillgång till en religiös röst och religiöst ledarskap, samt en hurdan kvinnlighet de kan anses representera. För det andra ser studien närmare på frågan om vad som händer med messiasmyten när en kvinna istället för en man tillåts rädda världen. En jämförelse görs mellan manliga och kvinnliga messiasgestalter och vissa tydliga olikheter särskilt i relation till frågor om religiös makt presenteras. Sofia Sjös avhandling visar på problem när det gäller frågor om kvinnligt religiöst ledarskap som även kan relateras till attityder i dagens värld, men pekar också på hur traditionella framställningar av både messiasmyt och kvinnlighet utmanas och förändras i det undersökta materialet.

[Säf, säf susa ; Die stille Stadt]

Soitinnus: lauluääni (mezzosopraano), piano.

POD-1/Tcf21 overexpression reduces endogenous SF-1 and StAR expression in rat adrenal cells

During gonad and adrenal development, the POD-1/capsulin/TCF21transcription factor negatively regulates SF-1/NR5A1expression, with higher SF-1 levels being associated with increased adrenal cell proliferation and tumorigenesis. In adrenocortical tumor cells, POD-1 binds to the SF-1 E-box promoter region, decreasing SF-1 expression. However, the modulation of SF-1 expression by POD-1 has not previously been described in normal adrenal cells. Here, we analyzed the basal expression of Pod-1 and Sf-1 in primary cultures of glomerulosa (G) and fasciculata/reticularis (F/R) cells isolated from male Sprague-Dawley rats, and investigated whether POD-1 overexpression modulates the expression of endogenous Sf-1 and its target genes in these cells. POD-1 overexpression, following the transfection of pCMVMycPod-1, significantly decreased the endogenous levels of Sf-1 mRNA and protein in F/R cells, but not in G cells, and also decreased the expression of the SF-1 target StAR in F/R cells. In G cells overexpressing POD-1, no modulation of the expression of SF-1 targets, StAR and CYP11B2, was observed. Our data showing that G and F/R cells respond differently to ectopic POD-1 expression emphasize the functional differences between the outer and inner zones of the adrenal cortex, and support the hypothesis that SF-1 is regulated by POD-1/Tcf21 in normal adrenocortical cells lacking the alterations in cellular physiology found in tumor cells.

SF e Animé : Os monstros encantadores do período pós-guerra.

O fascínio do poder de dotar de vida ao que está inanimado talvez possa ajudar a revelar o encanto que sentimos quando objectos fixos se começam a mover e a desenvolver coreografias cheias de vida. A técnica do desenho tornou-se o processo ideal para explorar estes temas por ser mais fácil desenhar robôs do que construir personagens, naves ou cenários futuristas para o cinema live-action. Assim, a animé favoreceu o género SF por precisamente ser mais económico a sua reprodução, tornando-a uma melhor escolha para um cheaper spectacle (Clements & McCarthy, 2006, p. 567). O motivo financeiro não foi a única razão, pois existem algumas questões importantes a explorar que reforçam esta tendência SF da animé . Após a 2ª grande guerra, no momento inicial da reconstrução do Japão, o Ground Zero, coincide com o desenvolvimento de uma cultura pop na qual os desenhos manga e a animé se tornaram referências fundamentais. Iremos verificar como das importantes particularidades dos filmes ou séries de animação japonesa são a exploração de imaginários SF onde o atómico é encanto monstruoso, que se controla ou pelo qual se é controlado. Com especial destaque às séries de televisão Prince Planet (Sato Okura, 1965), Gigantor (Mitsuteru Yokoyama, 1963) ou Astro Boy (Osamu Tezuka, 1963), iremos demonstrar que pela componente técnica ou visual da animação, a animé seja um específico modelo de estudo para tentar contextualizar atracções humanas por mundos controlados por máquinas, manipulação genética ou pela possibilidade de uma paisagem ciborgue.

SF e Animé : os Monstros Encantadores do Ground Zero

O fascínio do poder de dotar de vida ao que está inanimado talvez possa ajudar a revelar o encanto que sentimos quando os objectos fixos se começam a mover e a desenvolver coreografias cheias de vida. Na animé, a técnica do desenho tornou-se o processo ideal para explorar estes temas por ser mais fácil desenhar figuras monstruosas do que construir personagens, naves ou cenários futuristas para o cinema live-action. Após a II Grande Guerra, no momento inicial da reconstrução do Japão, o Ground Zero, coincide com o desenvolvimento de uma cultura pop na qual os desenhos manga e a animé se tornaram referências fundamentais. Iremos verificar como uma das importantes particularidades de séries de animação japonesa é a exploração de imaginários SF onde o atómico é encanto monstruoso, que se controla ou pelo qual se é controlado. Dando especial destaque às séries de televisão Prince Planet (Sato Okura, 1965), Gigantor (Mitsuteru Yokoyama, 1963) ou Astro Boy (Osamu Tezuka, 1963), iremos demonstrar que pela componente técnica ou visual da animação a animé é um modelo específico de estudo para tentar contextualizar a atracção humana por mundos controlados por máquinas, pela manipulação genética ou pela possibilidade de uma paisagem cyborg.

Health-related quality of life in Huntington's disease: a comparison of two generic instruments, SF-36 and SIP

Whereas several clinical endpoints in monitoring the response to treatment in patients with Huntington's disease (HD) have been explored, there has been a paucity of research in the quality of life in such patients. The aim of this study was to validate the use of two generic health-related quality of life instruments (the Short Form 36 health survey questionnaire [SF-36] and the Sickness Impact Profile [SIP]) and to evaluate their psychometric properties. We found that both instruments demonstrated acceptable convergent validity and reliability for patients and carers. However, there was an advantage in using the SF-36 because of its more robust construct validity and test-retest reliability; furthermore, motor symptoms appeared to influence some strictly nonmotor dimensions of the SIP. On a pragmatic level, the SF-36 is shorter and quicker to administer and, therefore, easier for patients at various stages of the disease to complete. Thus, the SF-36 would appear to be the recommended instrument of choice for patients with HD and their carers, although further work needs to be done to investigate the sensitivity of this instrument longitudinally. (C) 2004 Movement Disorder Society.

Measurement of apolipoprotein B-48 in the Svedberg flotation rate (Sf) > 400, Sf 60 – 400 and Sf 20 – 60 lipoprotein fractions reveals novel findings with respect to the effects of dietary fatty acids on triacylglycerol-rich lipoproteins in postmenopausal women

The present study was designed to examine whether the type of fat ingested in an initial test meal influences the response and density distribution of dietary-derived lipoproteins in the Svedberg flotation rate (Sf)>400, Sf 60 - 400 and Sf 20 - 60 lipoprotein fractions. A single-blind randomized within-subject crossover design was used to study the effects of palm oil, safflower oil, a mixture of fish and safflower oil, and olive oil on postprandial apolipoprotein (apo) B-48, retinyl ester and triacylglycerol responses in each lipoprotein fraction following an initial test meal containing one of the oils and a second standardized test meal. For all dietary oils, late postprandial (300min) concentrations of triacylglycerol and apo B-48 were significantly higher in the Sf 60 - 400 fraction than in the Sf>400 fraction (P<0.02). Significantly greater apo B-48 incremental areas under the curve (IAUCs) were also observed in the Sf 60 - 400 fraction than in the Sf>400 fraction following palm oil, safflower oil and olive oil (P<0.04), with a similar non-significant trend for fish/safflower oil. Olive oil resulted in a significantly greater apo B-48 IAUC in the Sf>400 fraction (P<0.02) than did any of the other dietary oils, as well as a tendency for a higher IAUC in the Sf 60 - 400 fraction compared with the palm, safflower and fish/safflower oils. In conclusion, we have found that the majority of intestinally derived lipoproteins present in the circulation following meals enriched with saturated, polyunsaturated or monounsaturated fatty acids are of the density and size of small chylomicrons and chylomicron remnants. Olive oil resulted in a greater apo B-48 response compared with the other dietary oils following sequential test meals, suggesting the formation of a greater number of small (Sf 60 - 400) and large (Sf>400) apo B-48-containing lipoproteins in response to this dietary oil.