PREDICTION OF NETILMICIN DISPOSITION IN NEONATES

Multiple regression analyses of data from 33 neonates who received netilmicin therapy showed that concurrent treatment with other drugs (Drg), creatinine clearance (CL(cr)), gestational age (GA), and an apgar score of less than 6 at 1 min (Agl') were significant determinants of netilmicin clearance. Apparent volume of distribution was significantly affected by postnatal age (PNA), gender, the presence of ascites and/or oedema (A/O), and whether or not the neonate was small for gestational age (SGA). The following formulae were obtained: CL (ml min-1 kg-1) = -0.108 - 0.210 (Drg) + 0.152(CL(cr)) + 0.019(GA) -0.128(Agl') (multiple R = 0.725, p

Diclofenac disposition in Indian cow and goat with reference to Gyps vulture population declines

Gyps vultures across India are declining rapidly and the NSAID diclofenac has been shown to be the major cause. Vultures scavenge livestock carcasses that have been treated with diclofenac within the days preceding death. We present data on diclofenac disposition in Indian cow and goat, and field data on the prevalence of diclofenac in carcases in the environment. In the disposition experiment, animals were treated with a single intramuscular injection of diclofenac at 1000 microg kg-1 bw. In cow, diclofenac was detectable in liver, kidney and intestine up to 71 h post-treatment; in plasma, half-life was 12.2 h. In goat, tissue residues were undetectable after 26 h. Prevalence of diclofenac in liver from 36 dead livestock collected in the field was 13.9%. Data suggest that diclofenac residues in Indian cow and goat are short-lived, but diclofenac prevalence in carcasses available to vultures may still be very high.

Stereoselective disposition of fluoxetine and norfluoxetine during pregnancy and breast-feeding

To compare the disposition of fluoxetine and norfluoxetine enantiomers in the mother, foetus and infant.

Summary of Criminal Records Disposition by Type For Period 7/1/2013 Thru 6/30/2014

This gives a summary of criminal records disposition by type.

The Impact of Critical Thinking Disposition on Learning Using Business Simulations

This research seeks to determine the relationship between students’ critical thinking disposition and their learning while engaging in a business simulation at a UK higher education institution (HEI). The research informs educators making decisions about the use of simulations as to the value of considering critical thinking dispositions. Previous research has found that simulations are an effective way for students to engage actively in learning, bridging the gap between theory and practice. It has also been found that such simulations can develop students’ critical thinking skills. However, hitherto no research has been undertaken into the role that existing critical thinking disposition has on the learning of students, as measured by the degree to which students perceived that they met the module’s intended learning outcomes. This research offers insights into the role and importance of critical thinking disposition and its component dimensions and how this impacts student learning. The results indicate that the level of critical thinking disposition is positively related to the students’ learning. The implications of the research suggest educators should target business simulations at specific cohorts of students. The relative importance of the critical thinking disposition constructs and the practical educational implications of these findings are discussed.

Arrêt du Conseil d'Etat qui ordonne que les payeurs des gages des Parlements et autres cours qui fourniront aux commis de Pierre Regnard dans quatre jours de la signification du présent arrêt, leurs soumissions de payer pour la réunion des offices de trésoriers de chancellerie les trois-quarts des sommes portées dans les rôles, seront déchargés du surplus

[Acte. 1715-02-12. Versailles]

Arrêt du Parlement qui décide que les offices domaniaux ou venaux sont propres de succession et de disposition, lorsqu'ils ont passé du père aux enfants

[Acte. 1709-02-09. Paris]

Arrêt du grand conseil concernant les abbayes du royaume (qui condamne Denis Coignet, curé de St-Roch à Paris et prieur de Saint-Julien de Courcelles, à payer à Franç. des Bertrons de Crillon, évêque de Vienne, 29 années d'arrérages de la cense par lui due audit des Bertrons, en sa qualité d'abbé de St-Florent-lez-Saumur dont relève ledit prieuré de Saint-Julien.)

[Acte. 1719-03-04. Paris]

Arrêt du grand conseil sur la manière de payer la dîme des raisins, et qui y assujettit indistinctement tout ce qui en croit dans une vigne. (En faveur du prieur de St-Pierre-le-Moutier, contre Fr. Moquot, commensal de la maison du roi)

[Acte. 1727-03-18. Paris]

Arrêt du grand conseil en faveur du Sr Loison, contre le Sr Royer, dit Saint-Laurent, garde du roi, confirmatif d'une sentence de la prévôté de l'hôtel qui condamne ledit Royer à payer au Sr Loison la somme de 3200 liv. contenue en sa reconnaissance du 8 août 1724

[Acte. 1730-08-22. Paris]