Diversidade genética de plantas daninhas revelada por AFLP. I. Proso Millet (Panicum miliaceum, L.).

2003

Manejo da cultura do milheto.

2003

Características do herbicida S-Metolachlor nas culturas de milho e sorgo.

2003

Caracteristicas do herbicida Carfentrazone Ethyl na cultura do milho.

2003

Plantas daninhas na cultura do sorgo.

2003

Eficiência dos dessecantes Paraquat e Diquat na qualidade fisiológica de sementes de milho.

2005

Plantas daninhas na cultura do milho.

2006

Seletividade de herbicidas na cultura do milho.

2007

Manejo de herbicidas na dessecação de pastagem e na cultura do milho consorciado com gramíneas forrageiras.

2008

Caracterização de plantas de milho sob estresse hídrico.

2009

Características do herbicida tembotrione na cultura do milho.

2009

Manejo das forrageiras dos gêneros Brachiaria e Panicum consorciadas com o milho em sistemas de Integração Lavoura-Pecuária.

2009

Separação e identificação de sementes de plantas não cultivadas ou espontâneas em áreas agrícolas.

2009

C-Kit(+) Cells Isolated from Developing Kidneys Are a Novel Population of Stem Cells with Regenerative Potential

The presence of tissue specific precursor cells is an emerging concept in organ formation and tissue homeostasis. Several progenitors are described in the kidneys. However, their identity as a true stem cell remains elusive. Here, we identify a neonatal kidney-derived c-kit(+) cell population that fulfills all of the criteria as a stem cell. These cells were found in the thick ascending limb of Henle's loop and exhibited clonogenicity, self-renewal, and multipotentiality with differentiation capacity into mesoderm and ectoderm progeny. Additionally, c-kit(+) cells formed spheres in nonadherent conditions when plated at clonal density and expressed markers of stem cells, progenitors, and differentiated cells. Ex vivo expanded c-kit(+) cells integrated into several compartments of the kidney, including tubules, vessels, and glomeruli, and contributed to functional and morphological improvement of the kidney following acute ischemia-reperfusion injury in rats. Together, these findings document a novel neonatal rat kidney c-kit(+) stem cell population that can be isolated, expanded, cloned, differentiated, and used for kidney repair following acute kidney injury. These cells have important biological and therapeutic implications. STEM Cells 2013;31:1644-1656

Genome-wide hydroxymethylcytosine pattern changes in response to oxidative stress

The TET enzymes convert methylcytosine to the newly discovered base hydroxymethylcytosine. While recent reports suggest that TETs may play a role in response to oxidative stress, this role remains uncertain, and results lack in vivo models. Here we show a global decrease of hydroxymethylcytosine in cells treated with buthionine sulfoximine, and in mice depleted for the major antioxidant enzymes GPx1 and 2. Furthermore, genome-wide profiling revealed differentially hydroxymethylated regions in coding genes, and intriguingly in microRNA genes, both involved in response to oxidative stress. These results thus suggest a profound effect of in vivo oxidative stress on the global hydroxymethylome.