光调制技术测量半导体激光器固有高频响应

采用一种新的全光纤连接的半导体激光器光调制技术,实现了对高速半导体激光器固有响应的直接测量。利用速率方程能够对光调制的动态响应过程进行准确的描述。基于对抽运源和探测器的频率响应对光调制数据准确性影响的分析,通过将网络分析仪校正到同轴端,然后用直接扣除法和相互扣除法,在网络分析仪外部对测量数据进行了修正。两种修正方法得到了一致的结果,并且同已有的理论和实验结果相符合。改进后的光调制技术和两种修正数据的方法不但提高了数据的精确性,而且扩展了测量的频率范围。

带隙法测定SiGe／Si材料的应变状态

从固体模型理论的结果出发，计算了生长于Si（100）衬底上x值小于0．85的Si1-xGex合金材料（能带结构为类蛳结构）的间接带隙与应变的关系，结果表明，应变的SiGe材料的带隙和完全弛豫状态下材料的带隙之差与应变呈线性关系．基于这一结果，提出了用测量带隙来间接测定SiGe／Si应变状态的方法．用带隙法和x射线双晶衍射法测量了不同应变状态下的SiGe／Si多量子阱材料的应变弛豫度，两者可以较好的符合，表明带隙法测量SiGe应变弛豫度是可行的．

牵拉力对共培养的表皮干细胞及成纤维细胞迁移行为的影响

<正>背景:创面愈合是一个复杂的动态过程,是细胞之间、细胞与细胞外基质及细胞因子间相互影响和协同作用的结果。另外,大量相关研究表明机械应力可以诱导组织细胞增殖,促进创面愈合。因此创面愈合也是一个典型的力学-生物学耦合过程,但力学刺激促进创面愈合的细胞/分子的调控机制目前尚不清楚。皮肤由多种细胞组成,通过牵张皮肤等在体方法难以区分其中某类细胞对外界力学刺激的单独响应以及不

~(169)Re的转动带结构研究(英文)

利用在束γ谱学方法 ,通过反应1 4 4 Sm( 2 8Si,1p3n) 1 69Re研究了1 69Re的激发态能级结构 .实验进行了X γ符合、γ γ符合、DCO系数和带内B(M1 ) B(E2 )比率测量 .基于这些测量 ,建立了组态为π9 2 - [51 4 ]的强耦合带和组态为π1 2 -[54 1 ]的退耦合带 .通过比较1 69Re的转动带与邻近奇质子核已知转动带的结构和B(M1 ) B(E2 )比率 ,指定了1 69Re转动带的组态 .实验观测到π9 2 - [51 4 ]和π1 2 - [54 1 ]转动带的中子AB带交叉的转动频率分别为 0 .2 3和 0 .2 7MeV .着重讨论了1 69Re转动带的中子AB带交叉频率、转动角动量顺排和旋称劈列等 ,并讨论了奇ARe核转动带结构的系统性

Effect of annealing on the deformation mechanism of a styrene/n-butyl acrylate copolymer latex film investigated by synchrotron small-angle X-ray scattering

The deformation mechanism of a styrene/n-butyl acrylate copolymer latex film subjected to uniaxial tensile stress was studied by small-angle X-ray scattering. The influence of annealing at 23, 60, 80, and 100 degrees C for 4 h on microscopic deformation processes was elucidated. It was demonstrated that the microscopic deformation mechanism of the latex films transformed gradually from nonaffine deformation behavior to affine deformation behavior with increasing annealing temperature.

Dissolution, characterization and photo functionalization of carbon nanotubes

A simple method to disperse carbon nanotubes (CNTs) has been achieved, which gives two photofunctionalized CNTs, hydrazine nanotubes (h-CNTs) and 1,3,4-oxadiazole nanotubes (o-CNTs). Results from FTIR, H-1 NMR spectroscopy and TEM observations showed that the functionalization was successful. The modified nanombes can dissolve in most of the nonpolar organic solvents and no precipitate was observed in the solution of the nanombes even after 2 months. The functionalized nanotubes showed photo-electronic properties, which is due to the attachment of the function groups to them as proved by steady-state fluorescence spectroscopy. Both h-CNTs and o-CNTs showed good thermal stability below 300 C and might be used as functional materials.

Impact of gene variants on sex-specific regulation of human Scavenger receptor class B type 1 (SR-BI) expression in liver and association with lipid levels in a population-based study.

BACKGROUND: Several studies have noted that genetic variants of SCARB1, a lipoprotein receptor involved in reverse cholesterol transport, are associated with serum lipid levels in a sex-dependent fashion. However, the mechanism underlying this gene by sex interaction has not been explored. METHODS: We utilized both epidemiological and molecular methods to study how estrogen and gene variants interact to influence SCARB1 expression and lipid levels. Interaction between 35 SCARB1 haplotype-tagged polymorphisms and endogenous estradiol levels was assessed in 498 postmenopausal Caucasian women from the population-based Rancho Bernardo Study. We further examined associated variants with overall and SCARB1 splice variant (SR-BI and SR-BII) expression in 91 human liver tissues using quantitative real-time PCR. RESULTS: Several variants on a haplotype block spanning intron 11 to intron 12 of SCARB1 showed significant gene by estradiol interaction affecting serum lipid levels, the strongest for rs838895 with HDL-cholesterol (p=9.2x10(-4)) and triglycerides (p=1.3x10(-3)) and the triglyceride:HDL cholesterol ratio (p=2.7x10(-4)). These same variants were associated with expression of the SR-BI isoform in a sex-specific fashion, with the strongest association found among liver tissue from 52 young women<45 years old (p=0.002). CONCLUSIONS: Estrogen and SCARB1 genotype may act synergistically to regulate expression of SCARB1 isoforms and impact serum levels of HDL cholesterol and triglycerides. This work highlights the importance of considering sex-dependent effects of gene variants on serum lipid levels.

Antigen-specific T-T interactions regulate CD4 T-cell expansion.

The regulation of CD4 T cell numbers during an immune response should take account of the amount of antigen (Ag), the initial frequency of Ag-specific T cells, the mix of naive versus experienced cells, and (ideally) the diversity of the repertoire. Here we describe a novel mechanism of T cell regulation that potentially deals with all of these parameters. We found that CD4 T cells establish a negative feedback loop by capturing their cognate MHC/peptide complexes from Ag-presenting cells and presenting them to Ag-experienced CD4 T cells, thereby inhibiting their recruitment into the response while allowing recruitment of naive T cells. The inhibition is Ag specific, begins at day 2 (long before Ag disappearance), and cannot be overcome by providing new Ag-loaded dendritic cells. In this way CD4 T cell proliferation is regulated in a functional relationship to the amount of Ag, while allowing naive T cells to generate repertoire variety.