HG 186.9-187.0 D.E-2

Coarse grained sediment with small patches of a fine grained domain. The domain may contain organic material. Lineations and minor grain stack present throughout the section.

HG 186.9-187.0 D.E-3

Fractured and weathered grains throughout the section. Lineations and grain stacks throughout the section.

HG 186.9-187.0 D.E-4

Fine grained domain within a coarse grained domain. Lineations throughout the section. A few small patches of a clay domain seen towards the top left.

HG 186.9-187.0 D.E.

Coarse grained sediment with a few fine grained matrices. Brown sediment with small to medium sized clasts. Clasts range from sub-angular to sub-rounded. Organic material present. It contains rotation structures throughout as well as edge-to-edge grain crushing. Fine grained clay domains are present and lineations can also be seen. Minor amounts of grain stacking can also be seen.

HG 186.9-187.0 D.E. Thin Section

Coarse grained sample with grains varying from small to medium in size. They range from sub-angular to sub-rounded in shape. The sample is abundant in lineations and comet structures. Minor amounts of grain stacking are present. Inclusions of a clay rich, fine grained domain.

HG 187.45-187.65 Thin Section

Coarse grained sediment with fine grained domains throughout. The clasts in the coarse grained domain range from sub-angular to sub-rounded. Short distance lineations are present throughout the sample. Organic rich domains (darker) are prevalent alongside fractured grains.

Functional studies of the deubiquitinating enzymes USP19, USP4 and UCH-L1

El marcaje de proteínas con ubiquitina, conocido como ubiquitinación, cumple diferentes funciones que incluyen la regulación de varios procesos celulares, tales como: la degradación de proteínas por medio del proteosoma, la reparación del ADN, la señalización mediada por receptores de membrana, y la endocitosis, entre otras (1). Las moléculas de ubiquitina pueden ser removidas de sus sustratos gracias a la acción de un gran grupo de proteasas, llamadas enzimas deubiquitinizantes (DUBs) (2). Las DUBs son esenciales para la manutención de la homeostasis de la ubiquitina y para la regulación del estado de ubiquitinación de diferentes sustratos. El gran número y la diversidad de DUBs descritas refleja tanto su especificidad como su utilización para regular un amplio espectro de sustratos y vías celulares. Aunque muchas DUBs han sido estudiadas a profundidad, actualmente se desconocen los sustratos y las funciones biológicas de la mayoría de ellas. En este trabajo se investigaron las funciones de las DUBs: USP19, USP4 y UCH-L1. Utilizando varias técnicas de biología molecular y celular se encontró que: i) USP19 es regulada por las ubiquitin ligasas SIAH1 y SIAH2 ii) USP19 es importante para regular HIF-1α, un factor de transcripción clave en la respuesta celular a hipoxia, iii) USP4 interactúa con el proteosoma, iv) La quimera mCherry-UCH-L1 reproduce parcialmente los fenotipos que nuestro grupo ha descrito previamente al usar otros constructos de la misma enzima, y v) UCH-L1 promueve la internalización de la bacteria Yersinia pseudotuberculosis.

O recurso de agravo e as diretrizes estabelecidas pela Lei nº 11.187/2005

O presente estudo tem como finalidade analisar o recurso de agravo que pode ter vários regimes jurídicos, ou procedimentos, bem como os efeitos causados no recebimento desse recurso. Intenta evidenciar as substâncias alterações sofridas pelo regime, expondo os dispositivos modificados, pela Lei 11.187/2005. Referindo-se a esta Lei, os legisladores buscaram trazer maior agilidade processual, no sentido de desafogar os Tribunais, ao restringirem o cabimento do agravo de instrumento apenas em casos que houver necessidade de tutela de urgência; ao exigirem a interposição oral e imediata do agravo retido em audiência de instrução e julgamento; e também através da ampliação dos poderes conferidos ao relator. Quanto a extinção do agravo interno contra a decisão do relator que converte o agravo de instrumento em agravo retido, caso não haja reconsideração do ato, alguns doutrinadores criticam esta medida, pois a irrecorribilidade, traz como consequência a possibilidade do mandado de segurança, conduzindo assim, a resultado contrário àquele qe as reformas iniciadas há mais de dez anos pretendiam, ou seja, a celeridade processual perante os tribunais.

Mary Eva Hite Papers - Accession 187

The Mary Eva Hite Papers consists of correspondence, speeches, newspaper clippings, family history data, photographs, awards, scrapbooks, and other records relating to Mary Eva Hite’s career as an educator and prominent South Carolina public servant. The photograph file provides a visual record of South Carolina elementary school life in the first half of the twentieth century. Correspondence relates to Dr. Hite’s many career activities, including her 1970 correspondence highlighting her work promoting the welfare of senior citizens. The speeches focus on her work with the aged, her travels abroad, and acceptances for awards presented to her by educational and civic organizations. Newspaper clippings provide information concerning awards presented to Dr. Hite and chronicle the advances in education made by the state of South Carolina. Scrapbooks relate to college friends and Dr. Hite’s work with Delta Kappa Gamma. There are also records relating to teacher retirement in South Carolina.

THE GEMINI NICI PLANET-FINDING CAMPAIGN: DISCOVERY OF A MULTIPLE SYSTEM ORBITING THE YOUNG A STAR HD 1160

We report the discovery of two low-mass companions to the young A0V star HD 1160 at projected separations of 81 +/- 5 AU (HD 1160 B) and 533 +/- 25 AU (HD 1160 C) by the Gemini NICI Planet-Finding Campaign. Very Large Telescope images of the system taken over a decade for the purpose of using HD 1160 A as a photometric calibrator confirm that both companions are physically associated. By comparing the system to members of young moving groups and open clusters with well-established ages, we estimate an age of 50(-40)(+50) Myr for HD 1160 ABC. While the UVW motion of the system does not match any known moving group, the small magnitude of the space velocity is consistent with youth. Near-IR spectroscopy shows HD 1160 C to be an M3.5 +/- 0.5 star with an estimated mass of 0.22(-0.04)(+0.03) M-circle dot, while NIR photometry of HD 1160 B suggests a brown dwarf with a mass of 33(-9)(+12) M-Jup. The very small mass ratio (0.014) between the A and B components of the system is rare for A star binaries, and would represent a planetary-mass companion were HD 1160 A to be slightly less massive than the Sun.