967 resultados para Cognate and noncognate words
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Dissertação de Mestrado, Neurociências Cognitivas e Neuropsicologia, Faculdade de Ciências Humanas e Sociais, Universidade do Algarve, 2016
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Either with words or images, the expression of feelings results, in a work of art, in communication. If this was not the case, the work would not require a spectator or a reader. And if words suggest images from what its author refers to and a countless number of figurations may happen, the images from a film reveal what you can see. We are often left with "just" the space for those facts to shape up as possible meanings to which we react with emotion or with a particular intellectualization, finding exactly what we call readings or interpretations. Starting from a definition of literature that we see spilled in the work prospected from the polysystem theory by Itamar Even-Zohar from the Porter Institute for Poetics and Semiotics (University of Tel-Aviv), we consider the dynamic character of every cultural moment/object. This is how a literary reading, that is to apply some of the methodologies in the interpretation of a literary work, is allowed to extend to other cultural objects. This is what we are going to do with Lars von Trier's Breaking the Waves, a landmark in cinema for what the movement and manifest Dogma 95 represents, but that for a literature reader particularly focused on the narration of love in its different manifestations - in which sex and faith are included - a corpus is revealed, filled with interpretative possibilities and emotional reactions, important condiments particularly to the spectator and/or interested reader.
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Le travail offre une vision d’ensemble des représentations du Moyen Âge tardif (XIVe-XVIe siècles), consacrées à des héroïnes féminines, en vue d’une étude de synthèse encore manquante sur le sujet. Le domaine culturel examiné est français, mais le panorama est élargi aux représentations provençales et toscanes quand on a de traces de représentation en France, même si le texte original est perdu. Les protagonistes des drames conservés sont des héroïnes de la foi : l’étude se focalise en particulier sur les drames qui mettent en scène des martyres. En outre, sont analysés d’un côté deux dialogues dramatiques latins de Hrotsvita (Xe siècle), qui constituent l’exemple le plus ancien d’un drame médiéval consacré à une sainte martyre, dans une perspective comparatiste qui prend aussi en compte la diachronie ; de l’autre côté, sont proposés des excursus sur le culte et l’iconographie ainsi qu’une comparaison avec les légendes hagiographiques. Le commentaire des textes du corpus révèle non seulement leurs qualités poétiques et leurs potentialités performatives, mais il présente aussi les constantes dramaturgiques qui les relient ainsi que les singularités qui les distinguent. Enfin, la comparaison avec deux exemples de drames européens de la même époque qui mettent en scène respectivement une héroïne historique et une figure légendaire, placées dans un horizon mondain et non saint, vient enrichir la lecture de l’héroïne martyre. La thèse se donne pour perspective de montrer que les problèmes posés par les textes (la stigmatisation du sujet féminin libre, la répression de la résistance au pouvoir, la contradiction entre un corps vulnérable et une parole puissante) sont d’un intérêt considérable non seulement pour le lecteur expert, mais aussi pour un spectateur et un metteur en scène potentiels, de sorte que se trouve justifiée la redécouverte de ces représentations médiévales par et sur les scènes d’aujourd’hui.
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Mode of access: Internet.
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Sequence-specific interactions between aminoacyl-tRNA synthetases and their cognate tRNAs both ensure accurate RNA recognition and prevent the binding of noncognate substrates. Here we show for Escherichia coli glutaminyl-tRNA synthetase (GlnRS; EC 6.1.1.18) that the accuracy of tRNA recognition also determines the efficiency of cognate amino acid recognition. Steady-state kinetics revealed that interactions between tRNA identity nucleotides and their recognition sites in the enzyme modulate the amino acid affinity of GlnRS. Perturbation of any of the protein-RNA interactions through mutation of either component led to considerable changes in glutamine affinity with the most marked effects seen at the discriminator base, the 10:25 base pair, and the anticodon. Reexamination of the identity set of tRNA(Gln) in the light of these results indicates that its constituents can be differentiated based upon biochemical function and their contribution to the apparent Gibbs' free energy of tRNA binding. Interactions with the acceptor stem act as strong determinants of tRNA specificity, with the discriminator base positioning the 3' end. The 10:25 base pair and U35 are apparently the major binding sites to GlnRS, with G36 contributing both to binding and recognition. Furthermore, we show that E. coli tryptophanyl-tRNA synthetase also displays tRNA-dependent changes in tryptophan affinity when charging a noncognate tRNA. The ability of tRNA to optimize amino acid recognition reveals a novel mechanism for maintaining translational fidelity and also provides a strong basis for the coevolution of tRNAs and their cognate synthetases.
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No abstract
The words about a “sea of trees”. Colonial and post-colonial narratives about Gorongosa (Mozambique)
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8º Congresso Ibérico de Estudos Africanos (CIEA8). Madrid, 2012
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This thesis provides an alternative framework to analyze power and ethics practiced in everyday conversations, which constitute processes of organizing. Drawing upon narrative frameworks, the analyses of messages posted on an online message board demonstrate people’s imaginative capacity to create relevant stories, in respect of their precise grasp of factual understandings, contextual relevance and evaluative/moral appropriateness, by appropriating others’ words. Based on the empirical analyses, the thesis indicates that studies on power and ethics in organizations can be re-oriented towards appreciating irremediable power imbalances by offering alternative ways of member’s denoting experiences of power.
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Dissertação de mestrado integrado em Psicologia
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versão acessível em http://ace2015.info/wp-content/uploads/2015/11/ACE_2015_submission_148.pdf
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Vegeu el resum a l'inici del document del fitxer adjunt.
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Previous studies have demonstrated that a region in the left ventral occipito-temporal (LvOT) cortex is highly selective to the visual forms of written words and objects relative to closely matched visual stimuli. Here, we investigated why LvOT activation is not higher for reading than picture naming even though written words and pictures of objects have grossly different visual forms. To compare neuronal responses for words and pictures within the same LvOT area, we used functional magnetic resonance imaging adaptation and instructed participants to name target stimuli that followed briefly presented masked primes that were either presented in the same stimulus type as the target (word-word, picture-picture) or a different stimulus type (picture-word, word-picture). We found that activation throughout posterior and anterior parts of LvOT was reduced when the prime had the same name/response as the target irrespective of whether the prime-target relationship was within or between stimulus type. As posterior LvOT is a visual form processing area, and there was no visual form similarity between different stimulus types, we suggest that our results indicate automatic top-down influences from pictures to words and words to pictures. This novel perspective motivates further investigation of the functional properties of this intriguing region.
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The reliance in experimental psychology on testing undergraduate populations with relatively little life experience, and/or ambiguously valenced stimuli with varying degrees of self-relevance, may have contributed to inconsistent findings in the literature on the valence hypothesis. To control for these potential limitations, the current study assessed lateralised lexical decisions for positive and negative attachment words in 40 middle-aged male and female participants. Self-relevance was manipulated in two ways: by testing currently married compared with previously married individuals and by assessing self-relevance ratings individually for each word. Results replicated a left hemisphere advantage for lexical decisions and a processing advantage of emotional over neutral words but did not support the valence hypothesis. Positive attachment words yielded a processing advantage over neutral words in the right hemisphere, while emotional words (irrespective of valence) yielded a processing advantage over neutral words in the left hemisphere. Both self-relevance manipulations were unrelated to lateralised performance. The role of participant sex and age in emotion processing are discussed as potential modulators of the present findings.
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In the celebration of the Oswaldo Cruz Institute centenary, we wanted to stress our concern with the relationship between two of its missions: research and education. What are the educational bases required for science and technology activities on health sciences for the future years? How can scientists collaborate to promote the popularization of academic knowledge and to improve a basic education for citizenship in an ethic and humanistic view? In this article we pointed out to need of commitment, even in the biomedical post-graduation level, of a more integrated philosophy that would be centered on health education, assuming health as a dynamic biological and social equilibrium and emphasizing the need of scientific popularization of science in a cooperative construction way, instead of direct transfer of knowledge, preserving also macro views of health problems in the development of very specific studies. The contemporary explosion of knowledge, particularly biological knowledge, imposes a need of continuous education to face the growing illiteracy. In order to face this challenge, we think that the Oswaldo Cruz Institute honors his dialectic profile of tradition and transformation, always creating new perspectives to disseminate scientific culture in innovated forms.
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cis-natural antisense transcripts (cis-NATs) are widespread in plants and are often associated with downregulation of their associated sense genes. We found that a cis-NAT positively regulates the level of a protein critical for phosphate homeostasis in rice (Oryza sativa). PHOSPHATE1;2 (PHO1;2), a gene involved in phosphate loading into the xylem in rice, and its associated cis-NATPHO1;2 are both controlled by promoters active in the vascular cylinder of roots and leaves. While the PHO1;2 promoter is unresponsive to the plant phosphate status, the cis-NATPHO1;2 promoter is strongly upregulated under phosphate deficiency. Expression of both cis-NATPHO1;2 and the PHO1;2 protein increased in phosphate-deficient plants, while the PHO1;2 mRNA level remained stable. Downregulation of cis-NATPHO1;2 expression by RNA interference resulted in a decrease in PHO1;2 protein, impaired the transfer of phosphate from root to shoot, and decreased seed yield. Constitutive overexpression of NATPHO1;2 in trans led to a strong increase of PHO1;2, even under phosphate-sufficient conditions. Under all conditions, no changes occurred in the level of expression, sequence, or nuclear export of PHO1;2 mRNA. However, expression of cis-NATPHO1;2 was associated with a shift of both PHO1;2 and cis-NATPHO1;2 toward the polysomes. These findings reveal an unexpected role for cis-NATPHO1;2 in promoting PHO1;2 translation and affecting phosphate homeostasis and plant fitness.