MARCXML: um padrão de descrição para recursos informacionais em Open Archives

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

The use of Open Reading frame ESTs (ORESTES) for analysis of the honey bee transcriptome

Abstract Background The ongoing efforts to sequence the honey bee genome require additional initiatives to define its transcriptome. Towards this end, we employed the Open Reading frame ESTs (ORESTES) strategy to generate profiles for the life cycle of Apis mellifera workers. Results Of the 5,021 ORESTES, 35.2% matched with previously deposited Apis ESTs. The analysis of the remaining sequences defined a set of putative orthologs whose majority had their best-match hits with Anopheles and Drosophila genes. CAP3 assembly of the Apis ORESTES with the already existing 15,500 Apis ESTs generated 3,408 contigs. BLASTX comparison of these contigs with protein sets of organisms representing distinct phylogenetic clades revealed a total of 1,629 contigs that Apis mellifera shares with different taxa. Most (41%) represent genes that are in common to all taxa, another 21% are shared between metazoans (Bilateria), and 16% are shared only within the Insecta clade. A set of 23 putative genes presented a best match with human genes, many of which encode factors related to cell signaling/signal transduction. 1,779 contigs (52%) did not match any known sequence. Applying a correction factor deduced from a parallel analysis performed with Drosophila melanogaster ORESTES, we estimate that approximately half of these no-match ESTs contigs (22%) should represent Apis-specific genes. Conclusions The versatile and cost-efficient ORESTES approach produced minilibraries for honey bee life cycle stages. Such information on central gene regions contributes to genome annotation and also lends itself to cross-transcriptome comparisons to reveal evolutionary trends in insect genomes.

Saphenofemoral arteriovenous fistula as hemodialysis access

Abstract Background An upper limb arteriovenous (AV) fistula is the access of choice for haemodialysis (HD). There have been few reports of saphenofemoral AV fistulas (SFAVF) over the last 10-20 years because of previous suggestions of poor patencies and needling difficulties. Here, we describe our clinical experience with SFAVF. Methods SFAVFs were evaluated using the following variables: immediate results, early and late complications, intraoperative and postoperative complications (up to day 30), efficiency of the fistula after the onset of needling and complications associated to its use. Results Fifty-six SFAVF fistulas were created in 48 patients. Eight patients had two fistulas: 8 patent (16%), 10 transplanted (20%), 12 deaths (24%), 1 low flow (2%) and 20 thrombosis (39%) (first two months of preparation). One patient had severe hypotension during surgery, which caused thrombosis of the fistula, which was successfully thrombectomised, four thrombosed fistulae were successfully thrombectomised and revised on the first postoperative day. After 59 months of follow-up, primary patency was 44%. Conclusion SFAVF is an adequate alternative for patients without the possibility for other access in the upper limbs, allowing efficient dialysis with good long-term patency with a low complication rate.

Cultura "Open" e nuovi modelli normativi per la gestione della conoscenza

L'obiettivo della ricerca è di compiere un'analisi dell'impatto della cosiddetta cultura "open" alla luce dell'attuale condizione del World Wide Web. Si prenderà in considerazione, in particolare, la genesi del movimento a partire dalle basi di cultura hacker e la relativa evoluzione nella filosofia del software libero, con il fine ultimo di identificare il ruolo attuale del modello open source nello scenario esistente. L'introduzione al concetto di Open Access completerà la ricerca anche considerando la recente riaffermazione della conoscenza come bene comune all'interno della Società dell'Informazione

Making business in the open: coping with economic and institutional risk and insecurity in the Kafue flats, Zambia

This paper deals with the difference between risk and insecurity from an anthropological perspective using a critical New Institutionalist approach. Risk refers to the ability to reduce undesirable outcomes, based on a range of information actors have on possible outcomes; insecurity refers to the lack of this information. With regard to the neo-liberal setting of a resource rich area in Zambia, Central Africa, local actors – men and women – face risk and insecurity in market constellations between rural and urban areas. They attempt to cope with risk using technical means and diversification of livelihood strategies. But as common-pool resources have been transformed from common property institutions to open access, also leading to unpredictability of competitors and partners in “free” markets, actors rely on magic options to reduce insecurity and transform it into risk-assessing strategies as an adaptation to modern times. Keywords: Risk, insecurity, institutional change, neo-liberal market, common pool resources, livelihood strategies, magic, Zambia.

Construcción de repositorios institucionales open source con Software Greenstone

Se aborda la construcción de repositorios institucionales open source con Software Greenstone. Se realiza un recorrido teórico y otro modélico desarrollando en él una aplicación práctica. El primer recorrido, que constituye el marco teórico, comprende una descripción, de: la filosofía open access (acceso abierto) y open source (código abierto) para la creación de repositorios institucionales. También abarca en líneas generales las temáticas relacionadas al protocolo OAI, el marco legal en lo que hace a la propiedad intelectual, las licencias y una aproximación a los metadatos. En el mismo recorrido se abordan aspectos teóricos de los repositorios institucionales: acepciones, beneficios, tipos, componentes intervinientes, herramientas open source para la creación de repositorios, descripción de las herramientas y finalmente, la descripción ampliada del Software Greenstone; elegido para el desarrollo modélico del repositorio institucional colocado en un demostrativo digital. El segundo recorrido, correspondiente al desarrollo modélico, incluye por un lado el modelo en sí del repositorio con el Software Greenstone; detallándose aquí uno a uno los componentes que lo conforman. Es el insumo teórico-práctico para el diseño -paso a paso- del repositorio institucional. Por otro lado, se incluye el resultado de la modelización, es decir el repositorio creado, el cual es exportado en entorno web a un soporte digital para su visibilización. El diseño del repositorio, paso a paso, constituye el núcleo sustantivo de aportes de este trabajo de tesina

Construcción de repositorios institucionales open source con Software Greenstone

Se aborda la construcción de repositorios institucionales open source con Software Greenstone. Se realiza un recorrido teórico y otro modélico desarrollando en él una aplicación práctica. El primer recorrido, que constituye el marco teórico, comprende una descripción, de: la filosofía open access (acceso abierto) y open source (código abierto) para la creación de repositorios institucionales. También abarca en líneas generales las temáticas relacionadas al protocolo OAI, el marco legal en lo que hace a la propiedad intelectual, las licencias y una aproximación a los metadatos. En el mismo recorrido se abordan aspectos teóricos de los repositorios institucionales: acepciones, beneficios, tipos, componentes intervinientes, herramientas open source para la creación de repositorios, descripción de las herramientas y finalmente, la descripción ampliada del Software Greenstone; elegido para el desarrollo modélico del repositorio institucional colocado en un demostrativo digital. El segundo recorrido, correspondiente al desarrollo modélico, incluye por un lado el modelo en sí del repositorio con el Software Greenstone; detallándose aquí uno a uno los componentes que lo conforman. Es el insumo teórico-práctico para el diseño -paso a paso- del repositorio institucional. Por otro lado, se incluye el resultado de la modelización, es decir el repositorio creado, el cual es exportado en entorno web a un soporte digital para su visibilización. El diseño del repositorio, paso a paso, constituye el núcleo sustantivo de aportes de este trabajo de tesina

Aiming at improving access to research output through the institutional repository

The paper is to introduce the institutional repository (IR) as a powerful tool to support the researchers of the institution to archive and disseminate their research findings freely to the scholarly community on the Internet. The IR can improve the access to an institution’s research output enormously. The operations of an IR also require various interactions with researchers, which enables the library to gain a solid understanding of research needs and expectations. Through such interaction, the relationship and mutual trust between researchers and the library are strengthened. The experiences of the Institute of Developing Economies (IDE) library can be useful to other special libraries.

Changes in Access to Health Services of the Immigrant and Native-Born Population in Spain in the Context of Economic Crisis

Aim: To analyze changes in access to health care and its determinants in the immigrant and native-born populations in Spain, before and during the economic crisis. Methods: Comparative analysis of two iterations of the Spanish National Health Survey (2006 and 2012). Outcome variables were: unmet need and use of different healthcare levels; explanatory variables: need, predisposing and enabling factors. Multivariate models were performed (1) to compare outcome variables in each group between years, (2) to compare outcome variables between both groups within each year, and (3) to determine the factors associated with health service use for each group and year. Results: unmet healthcare needs decreased in 2012 compared to 2006; the use of health services remained constant, with some changes worth highlighting, such as the decline in general practitioner visits among autochthons and a narrowed gap in specialist visits between the two populations. The factors associated with health service use in 2006 remained constant in 2012. Conclusion: Access to healthcare did not worsen, possibly due to the fact that, until 2012, the national health system may have cushioned the deterioration of social determinants as a consequence of the financial crisis. Further studies are necessary to evaluate the effects of health policy responses to the crisis after 2012.

Interlibrary loan trends : making access a reality /

"May 1992."

Importance and Benefits of OPEN SCIENCE for Ubiquitous Sharing, Dissemination and Impact

While openness is well applied to software development and exploitation (open sources), and successfully applied to new business models (open innovation), fundamental and applied research seems to lag behind. Even after decades of advocacy, in 2011 only 50% of the public-funded research was freely available and accessible (Archambault et al., 2013). The current research workflows, stemming from a pre-internet age, result in loss of opportunity not only for the researchers themselves (cf. extensive literature on topic at Open Access citation project, http://opcit.eprints.org/), but also slows down innovation and application of research results (Houghton & Swan, 2011). Recent studies continue to suggest that lack of awareness among researchers, rather than lack of e-infrastructure and methodology, is a key reason for this loss of opportunity (Graziotin 2014). The session will focus on why Open Science is ideally suited to achieving tenure-relevant researcher impact in a “Publish or Perish” reality. Open Science encapsulates tools and approaches for each step along the research cycle: from Open Notebook Science to Open Data, Open Access, all setting up researchers for capitalising on social media in order to promote and discuss, and establish unexpected collaborations. Incorporating these new approaches into a updated personal research workflow is of strategic beneficial for young researchers, and will prepare them for expected long term funder trends towards greater openness and demand for greater return on investment (ROI) for public funds.

Open Research Data

Open Research Data - A step by step guide through the research data lifecycle, data set creation, big data vs long-tail, metadata, data centres/data repositories, open access for data, data sharing, data citation and publication.

The impact of routine open nonsuction drainage on fluid accumulation after thyroid surgery: a prospective randomised clinical trial.

Background: Thyroid drains following thyroid surgery are routinely used despite minimal supportive evidence. Our aim in this study is to determine the impact of routine open drainage of the thyroid bed postoperatively on ultrasound-determined fluid accumulation at 24 hours. Methods: We conducted a prospective randomised clinical trial on patients undergoing thyroid surgery. Patients were randomly assigned to a drain group (n = 49) or a no-drain group (n = 44) immediately prior to wound closure. Patients underwent a neck ultrasound on day 1 and day 2 postoperatively. After surgery, we evaluated visual analogue scale pain scores, postoperative analgesic requirements, self-reported scar satisfaction at 6 weeks and complications. Results: There was significantly less mean fluid accumulated in the drain group on both day 1, 16.4 versus 25.1 ml (P-value = 0.005), and day 2, 18.4 versus 25.7 ml (P-value = 0.026), following surgery. We found no significant differences between the groups with regard to length of stay, scar satisfaction, visual analogue scale pain score and analgesic requirements. There were four versus one wound infections in the drain versus no-drain groups. This finding was not statistically significant (P = 0.154). No life-threatening bleeds occurred in either group. Conclusions: Fluid accumulation after thyroid surgery was significantly lessened by drainage. However, this study did not show any clinical benefit associated with this finding in the non-emergent setting. Drains themselves showed a trend indicating that they may augment infection rates. The results of this study suggest that the frequency of acute life-threatening bleeds remains extremely low following abandoning drains. We advocate abandoning routine use of thyroid drains. Trial registration: ISRCTN94715414.

Social Transformations and Survivals in the Spanish Navy: The Midshipmen’s Access Requirements (1717-1869)

This work studies the creation, development and evolution of the Spanish midshipmen, through their requirements, from the early 18th century to the second third of the 19th century. The aims are: to know deeply an essential post in the Navy –naval cadet- that still requires an exhaustive review; and, primarily, to link the transformations of the candidates’ requirements to the social debates which were proposed in Spain during this two centuries. The so-called transition from the estates society to the class society, or the step from a society of inheriting criteria to a society based on achieving variables, did not occur linearly; changes and inertia went hand in hand with contradictions and conflicts, thus in this paper the Spanish midshipmen are analysed by several relationally variables.