999 resultados para Uso racional de antimicrobianos


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The ageing process can change the pharmacodynamics and pharmacokinetics parameters. Therefore, some medications are considered potentially inappropriate (PIM) for the elderly people, since they can increase the likelihood of occurrence of adverse drug events. The objectives are to estimate the frequency of use of PIM in the elderly people, with potentially hazardous drug interactions (PHDI) and to evaluate the impact of pharmaceutical intervention (PI) for the prescription of safer therapeutic alternatives. A cross-sectional study was performed in a Health Family Strategy (region of Araraquara, SP), between January and February/2012. The medical records of patients aged ≥60 years, that use at least one drug, were consulted for identification of PIM, according to the Beers criteria. The MPI identified were classified considering the Anatomical Therapeutic Chemical Classification System (ATC) and the essentiality of the drug (safety, effectiveness, quality and cost parameters) The inclusion criteria were met by 358 elderly, being that 93 of them (26%) had taken at least one PIM. Of the 114 different drugs prescribed for elderly, ten were classified as PIM, of which four of them act on the central nervous system, four on cardiovascular system and two on the digestive tract. Seven MPI are essential medicines, belonging to national list of essential drugs (RENAME-2010). Fourteen drug interactions were identified, of which two are PHDI (fluoxetine/amitriptyline and digoxin/hydrochlorothiazide).After the PI, there was no change in medical prescriptions of patients with PIM use or with DI. Medical prescriptions of elderly attended in the Health Family Strategy show pharmacotherapeutic safety problems, of which may be responsible for health hazardous for this age group. Although the intervention carried out by letter had been ineffective for the adherence of doctors in prescribing safe alternatives, wide dissemination of the lists that contain PIM and PHDI is need, as well as the inclusion of safer equivalents in RENAME, in order to contribute for rational use of drugs.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Mastits is considered uncommon disease in mares. Streptococcus equi, Staphylococcus sp., Corynebacterium sp., Actinobacillus sp., Nocardia sp. and enterobacterias are major microorganisms involved in equine mammary infections. The disease is commonly related to traumatic lesions in mammary glands and teats. Edema, fibrosis, masses to palpation of glands, and viscous to seropurulent milk are mainly clinical signs observed in affected animals. The diagnosis is based on clinical exam of mammary glands and microbiological culture of the milk. There are no standard to use of indirect exams on diagnosis, including California Mastits Test and Somatic Cell Count. Systemic antimicrobials are recommended in therapy, based on previous “in vitro” susceptibility microbiological test. No specific control measures are indicated in equine mastits. The present study reviewed the mastits in mares, with emphasis to etiology, epidemiology findings, clinical manifestation, diagnosis, treatment and control aspects.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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The objective of this work was to verify the rational use of energy in restaurants of the city Botucatu, that apply the Good Manufacturing of Production (GMP). Ten restaurants were appraised regarding the number of meals and energy consumption. A check list of the sanitary surveillance was also applied, regarding just the related items to electric installation, ventilation, and equipment maintenance, that are related to the energy consumption. It was asked and observed if there were some program or orientation for conscious consumption or reduction of the energy consumption. The energy consumption of the restaurants was positively related to the number of served meals and operation time of the establishment. In none of the visited establishments it was observed the control measures of the energy consumption, neither cooling equipments of low energy consumption.

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Pós-graduação em Engenharia Mecânica - FEG

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Depuis que l'électricité a été découverte et que le secteur électrique s'est considérablement développé dans le XVIIIe siècle, jamais l'homme n'a pu se détacher de cette énergie. Pendant longtemps le système d'énergie électrique a fonctionné sans grand changement, mais avec le développement rapide des technologies, de nouvelles améliorations apparaissent. Ce mémoire traite des nouveaux concepts de réseaux d'énergie électrique appelés Réseaux intelligents ou Smart Grid. À travers un panorama de leurs développements dans le monde, cette étude porte d'une part, sur l'avancée des projets dans quelques pays et d'autre part, du niveau de développement de ce réseau au Brésil et de son intérêt pour le pays. L'étude a comme point central un des composants de ce réseau intelligent, le compteur communicant, qui est l'élément essentiel des interconnexions entre consommateurs et producteurs. Ce rapport apporte un éclaircissement sur les compteurs conventionnels et les compteurs intelligents et sur leur mode de fonctionnement. Enfin il aborde la question des consommateurs : par quels moyens leur transmettre tous ces changements à venir, puisque jusqu'à présent, leur seule participation était de payer l'énergie consommée. Avec le nouveau réseau, ils deviendront de véritables acteurs puisqu'ils seront informés en temps réel de leur consommation d'énergie électrique. Pour terminer, le mémoire montrera comment ils pourront s'adapter à cette nouvelle façon de gérer leur consommation en ésperant les inciter à une utilisation plus raisonnable de l'énergie et à modifier leur comportement en gérant de manière active leur consommation en intégrant notamment les énergies renouvelables

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Considering that the Brazilian energy source is based on hydroelectric power plants, every moment that it does not rain enough, we are likely to suffer power outage. Making the rational use of energy not only is wise, but also important for financial issues. The industrial sector is of great importance to Brazilian economic context, because it is one that creates more wealth and jobs. It should be noted that it is one of the sectors that consume more electricity. One of the most used equipment in industry is the three phase induction motor, which ends up providing significant waste of energy. For that reasons, studying three phase induction motors is important. One of the ways to evaluate the parameter of the three phase induction motor is using a dynamometer mechanic or electric. This work aims at further studies (and development) of electrodynamometer brake, a type of electrical dynamometer, that is the only one with reversible use. This means, it is possible to measure both the torque and the power transmitted by the electric motors, by the direct method and the indirect. Besides it allows greater stability in the imposition of charges, due to its nature of being able to regenerate the energy imparted by the engines being tested

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Pós-graduação em Agronomia (Proteção de Plantas) - FCA

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Depuis que l'électricité a été découverte et que le secteur électrique s'est considérablement développé dans le XVIIIe siècle, jamais l'homme n'a pu se détacher de cette énergie. Pendant longtemps le système d'énergie électrique a fonctionné sans grand changement, mais avec le développement rapide des technologies, de nouvelles améliorations apparaissent. Ce mémoire traite des nouveaux concepts de réseaux d'énergie électrique appelés Réseaux intelligents ou Smart Grid. À travers un panorama de leurs développements dans le monde, cette étude porte d'une part, sur l'avancée des projets dans quelques pays et d'autre part, du niveau de développement de ce réseau au Brésil et de son intérêt pour le pays. L'étude a comme point central un des composants de ce réseau intelligent, le compteur communicant, qui est l'élément essentiel des interconnexions entre consommateurs et producteurs. Ce rapport apporte un éclaircissement sur les compteurs conventionnels et les compteurs intelligents et sur leur mode de fonctionnement. Enfin il aborde la question des consommateurs : par quels moyens leur transmettre tous ces changements à venir, puisque jusqu'à présent, leur seule participation était de payer l'énergie consommée. Avec le nouveau réseau, ils deviendront de véritables acteurs puisqu'ils seront informés en temps réel de leur consommation d'énergie électrique. Pour terminer, le mémoire montrera comment ils pourront s'adapter à cette nouvelle façon de gérer leur consommation en ésperant les inciter à une utilisation plus raisonnable de l'énergie et à modifier leur comportement en gérant de manière active leur consommation en intégrant notamment les énergies renouvelables

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Considering that the Brazilian energy source is based on hydroelectric power plants, every moment that it does not rain enough, we are likely to suffer power outage. Making the rational use of energy not only is wise, but also important for financial issues. The industrial sector is of great importance to Brazilian economic context, because it is one that creates more wealth and jobs. It should be noted that it is one of the sectors that consume more electricity. One of the most used equipment in industry is the three phase induction motor, which ends up providing significant waste of energy. For that reasons, studying three phase induction motors is important. One of the ways to evaluate the parameter of the three phase induction motor is using a dynamometer mechanic or electric. This work aims at further studies (and development) of electrodynamometer brake, a type of electrical dynamometer, that is the only one with reversible use. This means, it is possible to measure both the torque and the power transmitted by the electric motors, by the direct method and the indirect. Besides it allows greater stability in the imposition of charges, due to its nature of being able to regenerate the energy imparted by the engines being tested