Inicio de las obras de la torre de Rectoría: un edificio de acero, vidrio y concreto

Terminados los edificios para las facultades de Derecho, Ingeniería Mecánica e Ingeniería Civil y una vez determinado el plan para la siguiente etapa de Ciudad Universitaria, se anunció la construcción de los edificios de Arquitectura, Comercio, el Estadio Olímpico y el más importante como sede del gobierno universitario: la torre de Rectoría

Hábitat sostenible: proyecto de mejoramiento integral de vivienda a partir de los activos sociales del territorio. Barrió Bella Flor, sector la Torre, localidad Ciudad Bolívar

Bogotá (Colombia): Universidad de La Salle. Facultad de Ciencias del Hábitat. Programa de Arquitectura

Avaliação do comportamento dinâmico da torre sineira da Sé Catedral do Funchal

O objetivo principal deste trabalho consiste na caracterização dinâmica da Torre Sineira da Sé Catedral do Funchal. Esta caracterização tem como base o recurso a técnicas de análise experimental, e em simultâneo, a simulações numéricas. As técnicas experimentais utilizadas baseiam-se na utilização de metodologias de identificação dinâmica com base em medições da resposta estrutural provocada pela excitação ambiente, i.e. vento e tráfego. A campanha de ensaios foi realizada em cinco séries de medição com acelerômetros piezoelétricos de alta sensibilidade e recorrendo a equipamento de aquisição de dados de alto desempenho. Ao longo do trabalho são descritas as principais características dos ensaios, bem como os resultados obtidos recorrendo a técnicas de análise modal operacional, culminando na obtenção dos parâmetros modais dos principais modos de vibração da estrutura. Após o tratamento dos resultados obtidos experimentalmente, estes foram usados para calibrar um modelo numérico implementado num software comercial de elementos finitos. Este modelo tem como base técnicas de modelação correntemente utilizadas na simulação deste tipo de estruturas, bem como parâmetros plausíveis para definir o comportamento mecânico dos materiais. Posteriormente, os resultados obtidos em ambas as abordagens são diretamente comparados, tendo sido possível observar uma boa correspondência entre ambos. Esta dissertação termina com as principais conclusões e com a identificação dos principais desenvolvimentos para trabalhos futuros.

Avaliação do comportamento dinâmico da torre sineira da Sé Catedral do Funchal

O objetivo principal deste trabalho consiste na caracterização dinâmica da Torre Sineira da Sé Catedral do Funchal. Esta caracterização tem como base o recurso a técnicas de análise experimental, e em simultâneo, a simulações numéricas. As técnicas experimentais utilizadas baseiam-se na utilização de metodologias de identificação dinâmica com base em medições da resposta estrutural provocada pela excitação ambiente, i.e. vento e tráfego. A campanha de ensaios foi realizada em cinco séries de medição com acelerômetros piezoelétricos de alta sensibilidade e recorrendo a equipamento de aquisição de dados de alto desempenho. Ao longo do trabalho são descritas as principais características dos ensaios, bem como os resultados obtidos recorrendo a técnicas de análise modal operacional, culminando na obtenção dos parâmetros modais dos principais modos de vibração da estrutura. Após o tratamento dos resultados obtidos experimentalmente, estes foram usados para calibrar um modelo numérico implementado num software comercial de elementos finitos. Este modelo tem como base técnicas de modelação correntemente utilizadas na simulação deste tipo de estruturas, bem como parâmetros plausíveis para definir o comportamento mecânico dos materiais. Posteriormente, os resultados obtidos em ambas as abordagens são diretamente comparados, tendo sido possível observar uma boa correspondência entre ambos. Esta dissertação termina com as principais conclusões e com a identificação dos principais desenvolvimentos para trabalhos futuros.

Cartografia das Aprendizagens das freguesias de Torre de Coelheiros, Nossa Senhora de Machede e São Miguel de Machede

O presente projeto de pesquisa foi concretizado no período compreendido entre os meses de Fevereiro de 2002 e de Dezembro de 2004. Durante este período, o projeto conheceu três fases distintas: 1) coinstituição da equipa de colaboradores, 2) conceção, construção e validação dos instrumentos de recolha de informação, 3) caracterização da população a estudar (pessoas e instituições).

Víctor Raúl Haya de la torre en Centroamérica, ¿La primera y última fase del aprismo internacional?

Resumen Estudia en impacto político e ideológico del viaje que realizara a Centroamérica, entre junio y diciembre de 1928, Víctor Raúl Haya de la Torre, fundador del APRA. Asimismo, revisa el pensamiento de ese líder Abstract The author studies the political and ideological impact of APRA  founder Víctor Raúl Haya de la Torres’s visit to Central America between June and December of 1928, and analyzes this leather’s thinking

El APRA, Haya de La Torre y la crisis del liberalismo guatemalteco en 1926-1929

ResumenEn julio de 1928 el líder del APRA visitó Guatemala. Durante poco más de un mes, Haya de la Torre dio conferencias, realizó una gira política por el altiplano occidental y en Quetzaltenango fundó el Comité Ejecutivo Centroamericano del APRA. La filiación política original de los simpatizantes de Haya de la Torre en Guatemala era el liberalismoAbstractWhen he visited Guatemala in July, 1928, the leader of APRA gave public lectures, went on a political tour of the western highlands, and in Quetzaltenango he founded the Central American Executive Committee of APRA. The political background of Haya de la Torre’s supporters in Guatemala was Liberalism.

Los intelectuales apristas y la cultura popular. Un acercamiento a las reflexiones de Luis Alberto Sánchez y Víctor Raúl Haya de la Torre

En el período de entreguerras, la ruptura con el positivismo por parte de numerosos pensadores produjo la emergencia de discursos relegitimadores de los sectores populares en todo el Continente. Este artículo aborda, desde una perspectiva de análisis del discurso, el pensamiento sobre el problema del indigenismo de dos intelectuales identificados con el aprismo: Luis Alberto Sánchez y Víctor Raúl Haya de la Torre. En este sentido, se intenta señalar continuidades y rupturas con otras corrientes indigenistas y analizar las estrategias discursivas presentes en los escritos apristas, cuyas particularidades están dadas por los intentos de construcción un partido político nacional/ continental.

Mineral paragenesis and fluid inclusion constraints on the Torre di Rio skarn, Island of Elba

The historical iron ore deposits of eastern Elba held great importance for the region and were its primary source of iron. The Torre di Rio skarn, despite its easily accessible outcrop and vicinity to the larger Rio Marina deposit, was never properly characterized. The results of petrographic and microthermometric study presented in this work provide new constraints on the Torre di Rio skarn. Mineral assemblage of ilvaite, calcite, quartz, iron oxides and sulphides combined with textural evidence indicate that Torre di Rio skarn does not fit into classical skarn model. The complex paragenetic sequence and overlapping of skarn and ore mineralogy is result of fast formation at relatively low temperatures evidenced by the silicon enrichment and pervasive nature of limonite alteration. Hematite-magnetite textural relationship points to boundary conditions of the ore fluid in terms of oxygen fugacity. Eutectic temperatures range from -16 to -33 °C indicating complex fluids. Calculated salinities range from 1.4 to 17.4 wt% NaCleq suggesting multiple fluids of different compositions. Total homogenization temperatures vary from 330 °C to 150 °C with both homogeneously and heterogeneously trapped FIAs. Ore deposition is concentrated where skarn formation was controlled primarily by phase separation during boiling. Calculated fluid pressure at boiling suggest shallow formation depth of a few hundred meters and constrains maximum temperature of ore deposition to c. 260 °C. This work suggest that relatively low salinities of fluid inclusions could indicate dominant marine origin of the hydrothermal fluids that were activated by the Porto Azzurro pluton emplacement and that scavenged Fe from sedimentary host rocks. During boiling at shallow depths and decreasing iron solubility, these fluids started precipitating Fe-minerals at Torre di Rio mineralization. Mixing with batches of more saline fluids at around 236 °C increased salinity abruptly and marked the end of ore deposition.

Seven-membered Rings Through Metal-free Rearrangement Mediated By Hypervalent Iodine.

A versatile and metal-free approach for the synthesis of carbocycles and of heterocycles bearing seven- and eight-membered rings is described. The strategy is based on ring expansion of 1-vinylcycloalkanols (or the corresponding silyl or methyl ether) mediated by the hypervalent iodine reagent HTIB (PhI(OH)OTs). Reaction conditions can be easily adjusted to give ring expansion products bearing different functional groups. A route to medium-ring lactones was also developed.

Association Between Cationic Liposomes And Low Molecular Weight Hyaluronic Acid.

This work presents a study of the association between low molecular weight hyaluronic acid (16 kDa HA) and cationic liposomes composed of egg phosphatidylcholine (EPC), 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE), and 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP). The cationic liposome/HA complexes were evaluated to determine their mesoscopic structure, average size, zeta potential, and morphology as a function of the amount of HA in the system. Small angle X-ray scattering results revealed that neighboring cationic liposomes either stick together after a partial coating of low concentration HA or disperse completely in excess of HA, but they never assemble as multilamellar vesicles. Cryo-transmission electron microscopy images confirm the existence of unilamellar vesicles and large aggregates of unilamellar vesicles for HA fractions up to 80% (w/w). High concentrations of HA (> 20% w/w) proved to be efficient for coating extruded liposomes, leading to particle complexes with sizes in the nanoscale range and a negative zeta potential.

EPR and magnetic studies of a carboxylate-bridged dinuclear copper(II) compound: [cu2(flu)4(dmf)2]

We report magnetic and EPR (electron paramagnetic resonance) spectroscopy studies of [Cu2(flu)4(dmf)2] (flu = flufenamate and dmf = dimethylformamide), which has CuII ions in tetracarboxylate "paddle wheel" dinuclear units. Susceptibility measurements at 10 < T < 275 K allowed the evaluation of an antiferromagnetic intradinuclear exchange coupling J0 = -294 ± 5 cm-1 between CuII ions (Hex = "J0 S1·S2). EPR experiments at 300 K in powder and single-crystals at 9.5 and 34.4 GHz indicated g// = 2.373, g⊥ = 2.073 and zero field splitting parameters D = (-0.334 ± 0.001) cm"1 and E ca. 0. EPR signal intensity measurements at X-band in the range 4 < T < 295 K indicated that J0 = "283 ± 5 cm"1. A higher limit |J´| < 5×10-3 cm-1 for the interdinuclear exchange coupling between neighbor units at ca.14.24 Å was estimated from the angular variation of the single crystal spectra around the magic angles. The results are discussed in terms of the structure of the dinuclear unit and the bridges connecting CuII ions and compared with values reported for similar compounds.

Protection against tuberculosis by a single intranasal administration of DNA-hsp65 vaccine complexed with cationic liposomes

Background: The greatest challenges in vaccine development include optimization of DNA vaccines for use in humans, creation of effective single-dose vaccines, development of delivery systems that do not involve live viruses, and the identification of effective new adjuvants. Herein, we describe a novel, simple technique for efficiently vaccinating mice against tuberculosis (TB). Our technique consists of a single-dose, genetic vaccine formulation of DNA-hsp65 complexed with cationic liposomes and administered intranasally. Results: We developed a novel and non-toxic formulation of cationic liposomes, in which the DNA-hsp65 vaccine was entrapped (ENTR-hsp65) or complexed (COMP-hsp65), and used to immunize mice by intramuscular or intranasal routes. Although both liposome formulations induced a typical Th1 pattern of immune response, the intramuscular route of delivery did not reduce the number of bacilli. However, a single intranasal immunization with COMP-hsp65, carrying as few as 25 mu g of plasmid DNA, leads to a remarkable reduction of the amount of bacilli in lungs. These effects were accompanied by increasing levels of IFN-gamma and lung parenchyma preservation, results similar to those found in mice vaccinated intramuscularly four times with naked DNA-hsp65 (total of 400 mu g). Conclusion: Our objective was to overcome the significant obstacles currently facing DNA vaccine development. Our results in the mouse TB model showed that a single intranasal dose of COMP-hsp65 elicited a cellular immune response that was as strong as that induced by four intramuscular doses of naked-DNA. This formulation allowed a 16-fold reduction in the amount of DNA administered. Moreover, we demonstrated that this vaccine is safe, biocompatible, stable, and easily manufactured at a low cost. We believe that this strategy can be applied to human vaccines to TB in a single dose or in prime-boost protocols, leading to a tremendous impact on the control of this infectious disease.

THE EFFECT OF REFRIGERATED STORAGE ON SENSORY PROFILE AND PHYSICAL-CHEMICAL CHARACTERISTICS OF MINIMALLY PASTEURIZED ORANGE JUICE

Minimal pasteurization of orange juice (OJ) consists of using minimum holding time and temperature to ensure partial inactivation of pectin methylesterase (PME). This process produces juice with preserved sensory attributes and has a better acceptance by consumers when compared with commercially pasteurized OJ. Sensory profile and physical-chemical characteristics of minimally processed OJ was determined, during refrigerated storage, for two OJ blends with different pH values and the same level of PME thermal inactivation. A selected and trained sensorial panel (n = 16) performed sensory analysis, based on a quantitative descriptive analysis, twice a week for 30 days, evaluating the attributes of appearance (suspended particles and color intensity), odor (natural orange and fermented orange) and flavor (orange characteristic, fermented orange, acid and bitter taste). Storage presented great effect on OJ sensory profile; however, it was not noticeable on physical-chemical characteristics.