Seven-membered Rings Through Metal-free Rearrangement Mediated By Hypervalent Iodine.
| Contribuinte(s) |
UNIVERSIDADE DE ESTADUAL DE CAMPINAS |
|---|---|
| Data(s) |
2015
27/11/2015
27/11/2015
|
| Resumo |
A versatile and metal-free approach for the synthesis of carbocycles and of heterocycles bearing seven- and eight-membered rings is described. The strategy is based on ring expansion of 1-vinylcycloalkanols (or the corresponding silyl or methyl ether) mediated by the hypervalent iodine reagent HTIB (PhI(OH)OTs). Reaction conditions can be easily adjusted to give ring expansion products bearing different functional groups. A route to medium-ring lactones was also developed. 20 1475-94 |
| Identificador |
Molecules (basel, Switzerland). v. 20, n. 1, p. 1475-94, 2015. 1420-3049 10.3390/molecules20011475 http://www.ncbi.nlm.nih.gov/pubmed/25599151 http://repositorio.unicamp.br/jspui/handle/REPOSIP/202048 25599151 |
| Idioma(s) |
eng |
| Relação |
Molecules (basel, Switzerland) Molecules |
| Direitos |
aberto |
| Fonte |
PubMed |
| Tipo |
Artigo de periódico |
