984 resultados para Martin, Joseph W. (Joseph William), 1884-1968


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Also published with title: History of my own time.

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At head of title: Department of the Interior. Hon. Thomas G. Murphy, minister. W.W. Cory, C.M.G., deputy minister. North West Territories and Yukon Branch. O.S. Finnie, director. "Notes on the musk-ox and the caribou, by R.M. Anderson, PH. D.": p.49-53.

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Bibliography: p. 425-457.

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"Continuée jusqu' en 1860 par J Chantrel, suivie d'une table générale, entiérement refondue, par Léon Gautier et d'un atlas historique spécialement dressé pour l'ouvrage par A.-H. Dufour."

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The collection was presented to the British museum (Nat. Hist.) by W. Wilson Saunders.

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Mode of access: Internet.

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Mode of access: Internet.

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The plates and portraits are printed on both sides.

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[No. 1] is extracted from J.C. Frémont. Report of exploring expedition to the Rocky Mountains in the year 1842; [no. 2-3] from U.S. Engineer dept. Notes of a military reconnoissance from Fort Leavenworth, in Missouri, to San Diego, in California ... By Lieut. Col. W.H. Emory; [no. 4] from U.S. Engineer dept. Exploration and survey of the valley of the Great Salt Lake in Utah.

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Cover title: Pictures.

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The interactions between Eph receptor tyrosine kinases and their ephrin ligands regulate cell migration and axon pathfinding. The EphA receptors are generally thought to become activated by ephrin-A ligands, whereas the EphB receptors interact with ephrin-B ligands. Here we show that two of the most widely studied of these molecules, EphB2 and ephrin-A5, which have never been described to interact with each other, do in fact bind one another with high affinity. Exposure of EphB2-expressing cells to ephrin-A5 leads to receptor clustering, autophosphorylation and initiation of downstream signaling. Ephrin-A5 induces EphB2-mediated growth cone collapse and neurite retraction in a model system. We further show, using X-ray crystallography, that the ephrin-A5-EphB2 complex is a heterodimer and is architecturally distinct from the tetrameric EphB2-ephrin-B2 structure. The structural data reveal the molecular basis for EphB2-ephrin-A5 signaling and provide a framework for understanding the complexities of functional interactions and crosstalk between A- and B-subclass Eph receptors and ephrins.

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We present an improved database of planktonic foraminiferal census counts from the Southern Hemisphere Oceans (SHO) from 15°S to 64°S. The SHO database combines 3 existing databases. Using this SHO database, we investigated dissolution biases that might affect faunal census counts. We suggest a depth/[DCO3]2- threshold of ~3800 m/[DCO3]2- = ~-10 to -5 µmol/kg for the Pacific and Indian Oceans, and ~4000 m/[DCO3]2- = ~0 to 10 µmol/kg for the Atlantic Ocean, under which core-top assemblages can be affected by dissolution and are less reliable for paleo-sea surface temperature (SST) reconstructions. We removed all core-tops beyond these thresholds from the SHO database. This database has 598 core-tops and is able to reconstruct past SST variations from 2° to 25.5°C, with a root mean square error of 1.00°C, for annual temperatures. To inspect dissolution affects SST reconstruction quality, we tested the data base with two "leave-one-out" tests, with and without the deep core-tops. We used this database to reconstruct Summer SST (SSST) over the last 20 ka, using the Modern Analog Technique method, on the Southeast Pacific core MD07-3100. This was compared to the SSST reconstructed using the 3 databases used to compile the SHO database. Thus showing that the reconstruction using the SHO database is more reliable, as its dissimilarity values are the lowest. The most important aspect here is the importance of a bias-free, geographic-rich, database. We leave this dataset open-ended to future additions; the new core-tops must be carefully selected, with their chronological frameworks, and evidence of dissolution assessed.