Very short delays prior to escape from potential predators may function efficiently as adaptive risk-assessment periods

Periods between predator detection and an escape response (escape delays) by prey upon attack by a predator often arise because animals trade-off the benefits such a delay gives for assessing risk accurately with the costs of not escaping as quickly as possible. We tested whether freezing behaviour (complete immobility in a previously foraging bird) observed in chaffinches before escaping from an approaching potential threat functions as a period of risk-assessment, and whether information on predator identity is gained even when time available is very short. We flew either a model of a sparrowhawk (predator) or a woodpigeon (no threat) at single chaffinches. Escape delays were significantly shorter with the hawk, except when a model first appeared close to the chaffinch. Chaffinches were significantly more vigilant when they resumed feeding after exposure to the sparrowhawk compared to the woodpigeon showing that they were able to distinguish between threats, and this applied even when time available for assessment was short (an average of 0.29 s). Our results show freezing in chaffinches functions as an effective economic risk assessment period, and that threat information is gained even when very short periods of time are available during an attack.

Zinc chelatase in human lymphocytes: detection of the enzymatic defect in erythropoietic protoporphyria

We describe a fluorometric assay for heme synthetase, the enzyme that is genetically deficient in erythropoietic protoporphyria. The method, which can readily detect activity in 1 microliter of packed human lymphocytes, is based on the formation of zinc protoheme from protoporphyrin IX. That zinc chelatase and ferrochelatase activities reside in the same enzyme was shown by the competitive action of ferrous ions and the inhibitory effects of N-methyl protoporphyrin (a specific inhibitor of heme synthetase) on zinc chelatase. The Km for zinc was 11 micrograms and that for protoporphyrin IX was 6 microM. The Ki fro ferrous ions was 14 microM. Zinc chelatase was reduced to 15.3% of the mean control activity in lymphocytes obtained from patients with protoporphyria, thus confirming the defect of heme biosynthesis in this disorder. The assay should prove to be useful for determining heme synthetase in tissues with low specific activity and to investigate further the enzymatic defect in protoporphyria.

Genetic heterogeneity in erythropoietic protoporphyria: a study of the enzymatic defect in nine affected families

Erythropoietic protoporphyria (EPP) is associated with a deficiency of protohaem ferrolyase. We have used a novel assay for this enzyme based on its ability to utilize zinc as a substrate to investigate the inheritance of EPP in nine affected families. Zinc chelatase activity was markedly reduced in peripheral blood mononuclear cells from 14 EPP patients (mean, 3.3 nmol Zn protohaem/h/mg protein; range, 0.3-8.0) when compared with 41 controls (16.8 +/- 3.6) p less than 0.01. In three families with parent-to-child transmission of disease, the asymptomatic parent had an enzymatic activity within the normal range. In three pedigrees where the parents were asymptomatic, enzymatic activities were below the 95% confidence limits in both. Zinc chelatase activity was below the mean control value in 17 of the 18 parents in nine affected pedigrees, and six of seven asymptomatic offspring of patients with protoporphyria. The findings suggest that EPP is not transmitted as a simple dominant trait and that inheritance of more than one gene may be required for disease expression.

Bargaining over strategies of non-cooperative games

We propose a bargaining process supergame over the strategies to play in a non-cooperative game. The agreement reached by players at the end of the bargaining process is the strategy profile that they will play in the original non-cooperative game. We analyze the subgame perfect equilibria of this supergame, and its implications on the original game. We discuss existence, uniqueness, and efficiency of the agreement reachable through this bargaining process. We illustrate the consequences of applying such a process to several common two-player non-cooperative games: the Prisoner’s Dilemma, the Hawk-Dove Game, the Trust Game, and the Ultimatum Game. In each of them, the proposed bargaining process gives rise to Pareto-efficient agreements that are typically different from the Nash equilibrium of the original games.

Exploiting thermally-reversible chemistry for controlling the crosslinking of polymer networks

High explosives are highly sensitive to accidental detonation by impact, fire, shrapnel and small arms fire. This sensitivity can be reduced by storing the energetic material within a rubbery polymer matrix and are known as plastic bonded explosives (PBX). The current procedure used to manufacture PBX involves mixing the energetic material with a hydroxy-functionalised aliphatic polymer. Upon the addition of an isocyanate crosslinker an immediate polymerisation occurs and thus the rapidly curing mixture must be used to fill the missile or shells, referred to as ‘stores’. This process can lead to poor distribution of the crosslinker resulting in the formation of an inhomogeneously crosslinked matrix and the formation of voids. One solution to this problem involves containing the crosslinker within polyurethane microcapsules that are uniformly dispersed in the explosive-polymer mixture. Upon the application of a stimulus the crosslinker can be released from the microcapsules and the formation of a uniformly crosslinked PBX achieved. Herein is reported the design and synthesis of polyurethane microcapsules that release isocyanate crosslinkers when desired using a thermal stimulus. This has been achieved by exploiting the thermally-reversible nature of oxime-urethane and Diels-Alder adducts that have been incorporated into the shell wall of the microcapsules. An alternative approach to controlling the polymerisation of PBX materials has also been achieved using thermally-reversible blocked isocyanates that regenerate the isocyanate crosslinker when exposed to heat.

O processo decisório para obtenção de materiais de emprego militar no Exército Brasileiro

Este trabalho tem como objetivo descrever como os fatores racionais, organizacionais e políticos influenciam o processo decisório no Exército Brasileiro para a obtenção de Materiais de Emprego Militar (MEM). Utilizou-se a abordagem proposta no trabalho de Allison para análise das decisões durante a crise dos mísseis de Cuba em 1962. Os fatores racionais utilizados foram: cálculo, maximização de valor, impessoalidade, escolha racional e racionalidade limitada. Os fatores organizacionais foram: padrões e processos organizacionais, segmentação do problema, coordenação e controle centralizados, flexibilidade limitada, previsibilidade e cultura organizacional. Os fatores políticos utilizados foram: conflito, poder, negociação, contingências, cooptação, interesses e influência externa. Os resultados permitiram constatar que o processo decisório, mesmo ocorrendo em uma organização baseada em pressupostos racionais, sofre influência de fatores organizacionais e políticos.

Método dinâmico aplicado para antenas cilíndricas

Nowadays there has been a major breakthrough in the aerospace area, with regard to rocket launches to research, experiments, telemetry system, remote sensing, radar system (tracking and monitoring), satellite communications system and insertion of satellites in orbit. This work aims at the application of a circular cylindrical microstrip antenna, ring type, and other cylindrical rectangular in structure of a rocket or missile to obtain telemetry data, operating in the range of 2 to 4 GHz, in S-band. Throughout this was developed just the theoretical analysis of the Transverse transmission line method which is a method of rigorous analysis in spectral domain, for use in rockets and missiles. This analyzes the spread in the direction "ρ" , transverse to dielectric interfaces "z" and "φ", for cylindrical coordinates, thus taking the general equations of electromagnetic fields in function of e [1]. It is worth mentioning that in order to obtain results, simulations and analysis of the structure under study was used HFSS program (High Frequency Structural Simulator) that uses the finite element method. With the theory developed computational resources were used to obtain the numerical calculations, using Fortran Power Station, Scilab and Wolfram Mathematica ®. The prototype was built using, as a substrate, the ULTRALAM ® 3850, of Rogers Corporation, and an aluminum plate as a cylindrical structure used to support. The agreement between the measured and simulated results validate the established processes. Conclusions and suggestions are presented for continuing this work

A adesão do Brasil ao TNP: uma análise da trajetória da questão nuclear brasileira nos governos de Fernando Collor de Mello (1990-92) e Fernando Henrique Cardoso (1995-98)

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

A cooperação internacional em programas de produtos de defesa e seus atores: o caso Brasil e África do Sul no desenvolvimento do míssil A-Darter

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Análise de riscos envolvendo reações exotérmicas

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Cultura escrita em contextos indígenas

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Principais queixas vocais de pacientes idosos pós-tratamento para hanseníase

A hanseníase é uma doença infecto-contagiosa, cujo comprometimento vocal manifesta-se desde rouquidão à dificuldade respiratória. OBJETIVO: Comparar as principais queixas vocais entre pacientes idosos pós-tratamento para hanseníase e um grupo controle. FORMA DE ESTUDO: Descritivo prospectivo. MATERIAL E MÉTODO: Foram incluídos 50 pacientes com idade superior a 60 anos; 32 haviam sido tratados para hanseníase e os demais constituíram o grupo-controle. Houve aplicação de questionário próprio, sendo analisados os sintomas vocais apresentados pelos dois grupos,assim como sexo, faixa etária, hábitos de vida e comorbidades. RESULTADOS: Dentro do grupo pós-tratamento, os sintomas mais frequentes foram pigarro (34,4%) e rouquidão (28,1%), enquanto que no grupo controle os sintomas mais prevalentes foram pigarro (77,8%) e sensação de corpo estranho (55,6%). CONCLUSÃO: Os sintomas vocais mais prevalentes em pacientes pós-tratamento para hanseníase são o pigarro e a rouquidão e sua evolução é influenciada pelos hábitos de vida e por doenças associadas.