Classificação de cônicas e quádricas

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Cálculo diferencial e integral no movimento dos planetas

Pós-graduação em Matemática em Rede Nacional - IBILCE

Mídia: material didático ou instrumento manipulador? : o que dizem os estudos?

Este estudo teve como objetivo compreender a mídia e o universo didáticopedagógico, e assim como o uso dos meios midiáticos podem contribuir frente a aprendizagem . A pesquisa mostra esse novo aluno, como também esse novo professor, e quais os desafios que ambos passam por usarem os meios de comunicação, em especialmente a tecnologia. Para tanto foi realizada uma pesquisa documental, e diversos autores dialogaram entre si diante do tema apresentado. O estudo pautou-se pela abordagem qualitativa, fundamentada a partir de alguns autores. A pesquisa mostrou que com o avanço tecnológico os jovens se interessaram mais com os estudos, já que a informação ficou cada vez mais rápida, contudo mostrou também que alguns professores têm certo tipo de receio de usar outros materiais didáticos além do tradicional. O estudo também mostrou que apesar dos benefícios que a mídia traz, o importante é estarmos atentos já que tem-se um excesso de informações, e precisamos selecionar uma informação boa de uma ruim

A contribuição dos filmes na formação de professores

Participei do projeto de extensão Grupo de Formação: Diálogo e Alteridade, constituído por graduandos do curso de Pedagogia. Esse projeto está articulado a um curso de extensão, oferecido para professoras coordenadoras, vice-diretoras e coordenadoras pedagógicas do município de Rio Claro, e do qual também participam os graduandos. O curso, ao longo de dois anos (2011-2012), teve a pretensão de promover a sensibilização do olhar através do uso dos filmes. Em virtude das experiências vividas durante o curso e da grande presença das tecnologias em nossa sociedade, a presente pesquisa objetivou compreender quais as contribuições das mídias e dos filmes no ambiente escolar, tanto em relação ao trabalho pedagógico com os alunos como nos processos de formação continuada de professores e gestores. A partir de uma pesquisa bibliográfica realizada nos Anais da ANPEd (Associação Nacional de Pós-Graduação e Pesquisa em Educação) e do ENDIPE (Encontro Nacional de Didática e Prática de Ensino) sistematizei a produção científica que trata dos filmes no contexto educacional. Na busca por compreender quais as contribuições dos filmes para a formação das educadoras que participaram do referido curso, foi desenvolvida uma pesquisa documental a partir dos registros da pesquisadora e das escritas produzidas pelas participantes do referido curso. A pesquisa pretende contribuir para a ampliação e socialização das produções científicas acerca da temática

Um estudo de retas do plano e uma abordagem para o ensino médio com o software GeoGebra

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Repositórios de objetos de aprendizagem de língua portuguesa no ensino fundamental: alternativas para professores

Pós-graduação em Letras - FCLAR

Uma experiência de cibereducação para o letramento digital

Pós-graduação em Letras - FCLAR

Os problemas clássicos da Grécia antiga

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Função afim e suas propriedades através da resolução de problemas

Pós-graduação em Matemática em Rede Nacional - IBILCE

Estilos de aprendizagem e interfaces online: aporte ao ensino presencial em saúde, na disciplina Interação Universidade-Serviço-Comunidade I da Faculdade de Medicina de Botucatu-UNESP

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estilos de aprendizagem e interfaces online: aporte ao ensino presencial em saúde, na disciplina Interação Universidade-Serviço-Comunidade I da Faculdade de Medicina de Botucatu-UNESP

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Antioxidant Effects of Quercetin and Catechin Encapsulated into PLGA Nanoparticles

Polymeric nanoparticles (PLGA) have been developed for the encapsulation and controlled release of quercetin and catechin. Nanoparticles were fabricated using a solvent displacementmethod. Physicochemical properties were measured by light scattering, scanning electron microscopy and zeta-potential, X-ray diffraction, infrared spectroscopy and differential scanning calorimetry. Encapsulation efficiency and in vitro release profiles were obtained from differential pulse voltammetry experiments. Antioxidant properties of free and encapsulated flavonoids were determined by TBARS, fluorescence spectroscopy and standard chelating activity methods. Relatively small (d approximate to 400 nm) polymeric nanoparticles were obtained containing quercetin or catechin in a non-crystalline form (EE approximate to 79%) and the main interactions between the polymer and each flavonoid were found to consist of hydrogen bonds. In vitro release profiles were pH-dependant, the more acidic pH, the faster release of each flavonoid from the polymeric nanoparticles. The inhibition of the action of free radicals and chelating properties, were also enhanced when quercetin and catechin were encapsulated within PLGA nanoparticles. The information obtained from this study will facilitate the design and fabrication of polymeric nanoparticles as possible oral delivery systems for encapsulation, protection and controlled release of flavonoids aimed to prevent oxidative stress in human body or food products.

Three-Dimensional Ultrasonographic Assessment of Fetal Total Lung Volume as a Prognostic Factor in Primary Pleural Effusion

Objectives-The purpose of this study was to predict perinatal outcomes using fetal total lung volumes assessed by 3-dimensional ultrasonography (3DUS) in primary pleural effusion. Methods-Between July 2005 and July 2010, total lung volumes were prospectively estimated in fetuses with primary pleural effusion by 3DUS using virtual organ computer-aided analysis software. The first and last US examinations were considered in the analysis. The observed/expected total lung volumes were calculated. Main outcomes were perinatal death (up to 28 days of life) and respiratory morbidity (orotracheal intubation with mechanical respiratory support >48 hours). Results-Twelve of 19 fetuses (63.2%) survived. Among the survivors, 7 (58.3%) had severe respiratory morbidity. The observed/expected total lung volume at the last US examination before birth was significantly associated with perinatal death (P < .01) and respiratory morbidity (P < .01) as well as fetal hydrops (P < .01) and bilateral effusion (P = .01). Conclusions-Fetal total lung volumes may be useful for the prediction of perinatal outcomes in primary pleural effusion.

A randomized controlled trial of fetal endoscopic tracheal occlusion versus postnatal management of severe isolated congenital diaphragmatic hernia

Objective Severe pulmonary hypoplasia and pulmonary arterial hypertension are associated with reduced survival in congenital diaphragmatic hernia (CDH). We aimed to determine whether fetal endoscopic tracheal occlusion (FETO) improves survival in cases of severe isolated CDH. Methods Between May 2008 and July 2010, patients whose fetuses had severe isolated CDH (lung-to-head ratio < 1.0, liver herniation into the thoracic cavity and no other detectable anomalies) were assigned randomly to FETO or to no fetal intervention (controls). FETO was performed under maternal epidural anesthesia supplemented with fetal intramuscular anesthesia. Tracheal balloon placement was achieved with ultrasound guidance and fetoscopy between 26 and 30 weeks of gestation. All cases that underwent FETO were delivered by the EXIT procedure. Postnatal therapy was the same for both treated fetuses and controls. The primary outcome was survival to 6 months of age. Other maternal and neonatal outcomes were also evaluated. Results Twenty patients were enrolled randomly to FETO and 21 patients to standard postnatal management. The mean gestational age at randomization was similar in both groups (P = 0.83). Delivery occurred at 35.6 +/- 2.4 weeks in the FETO group and at 37.4 +/- 1.9 weeks in the controls (P < 0.01). In the intention-to-treat analysis, 10/20 (50.0%) infants in the FETO group survived, while 1/21 (4.8%) controls survived (relative risk (RR), 10.5 (95% CI, 1.5-74.7), P < 0.01). In the receivedtreatment analysis, 10/19 (52.6%) infants in the FETO group and 1/19 (5.3%) controls survived (RR, 10.0 (95% CI, 1.4-70.6) P < 0.01). Conclusion FETO improves neonatal survival in cases with isolated severe CDH. Copyright (C) 2011 ISUOG. Published by John Wiley & Sons, Ltd.

Polymeric Nanoparticles as Oral Delivery Systems for Encapsulation and Release of Polyphenolic Compounds: Impact on Quercetin Antioxidant Activity & Bioaccessibility

A delivery system containing polymeric (Eudragit) nanoparticles has been developed for encapsulation and controlled release of bioactive flavonoids (quercetin). Nanoparticles were fabricated using a solvent displacement method. Particle size, morphology, and charge were measured by light scattering, electron microscopy and zeta-potential. Encapsulation efficiency (EE) and release profiles were determined using electrochemical methods. Molecular interactions within the particle matrix were characterized by X-ray diffraction, differential scanning calorimetry, and infrared spectroscopy. Antioxidant properties of free and encapsulated quercetin were analyzed by TBARS and fluorescence spectroscopy. Bioaccessibility of quercetin was evaluated using an in vitro digestion model. Relatively small (d a parts per thousand aEuro parts per thousand 370 nm) anionic polymeric nanoparticles were formed containing quercetin in a non-crystalline form (EE a parts per thousand aEuro parts per thousand 67 %). The main interaction between quercetin and Eudragit was hydrogen bonding. Encapsulated quercetin remained stable during 6 months storage and maintained its antioxidant activity. Quercetin bioaccessibility within simulated small intestinal conditions was improved by encapsulation. The knowledge obtained from this study will facilitate the rational design and fabrication of polymeric nanoparticles as oral delivery systems for encapsulation, protection, and release of bioactive compounds.