Interface cena e tecnologia : composições cênicas mediadas

Based on the presupposition that the arts in the West always counted on resources, supports, and devices pertaining to its time context, an reflection is intended regarding the scenic compositions mediated by digital technologies do. Such technologies are inserted in the daily routine, also composing artistic experiments, thus playing a dialogical role with the art/technology intersection. Therefore, the proposal is to investigate what relationships are established in the contemporary theatrical scene from the contagion by digital technologies, aiming at establishing this parallel through a dialogue with the authors discussing the subject, and also based on the group practices having technological resources as a determinant factor in their plays. Furthermore, a reflection should be made on the scene that incorporates or is carried out in intermediatic events, analyzing how digital technologies (re)configure compositional processes of the plays by GAG Phila7, in the city of São Paulo/SP. For such, the dissertation is organized in three sections comprising four moments, to wit: brief overview of the field, contextualization, poetic analysis and synthesis. Qualitative methods are used as the methodological proposal: semi-structure interview, note and document taking (program, website, playing book, disclosure material for advertising text, photographs, and videos). Within the universe of qualitative research, it works with the epistemological perspective of the Gadamer philosophical hermeneutics. The possibilities allowed by the double virtual (Internet/web) generated a type of theater with another material basis and new forms of organization and structure, being possible to perceive that such technological advances and the arts are mutually contaminated, generating a dislocation in the logics of theatrical composition, movement beginning with the artistic vanguards, gradually intensified, thus offering new possibilities of constructions and hybridization of the of the most different possible types. Experiment ―Profanações_superfície de eventos de construção coletiva‖, idealized by Phila7 is inserted in this perspective. Object of the discussion of such research, the experiment works with possible poetics arising from the intersection with the digital technologies, aiming at identifying and problematizing the challenges from the technological evolution and expansion in a scenic context

Revitalização dos saberes e práticas Kaingang sobre as plantas tradicionais como proposta de educação ambiental na terra indígena Ligeiro

O presente trabalho objetiva investigar a Revitalização dos Saberes e Práticas Kaingang Sobre as Plantas Tradicionais como Proposta de Educação Ambiental na comunidade Terra Indígena de Ligeiro no município de Charrua - RS. Trata-se de uma pesquisa de campo que busca melhor compreender o que provocou o abandono e esquecimento desses saberes, bem como possíveis alternativas teóricas e práticas para que a revitalização dos saberes culturais ancestrais seja realizada. Justifica-se pelo fato da utilização de plantas medicinais para o tratamento de enfermidades estar enraizada nas culturas indígenas e poder assim suprir, em parte, a deficiente atenção à saúde e as realidades da fome em muitas T.I. Foram realizadas visitas a campo para análise da situação atual e coleta de informações, com aplicação de entrevistas com vários indígenas, bem como com kujà e curandeiras; se implantou um horto medicinal com várias plantas, ervas e se distribuíram mudas de plantas frutíferas nativas. Para este projeto, dois alunos indígenas do IFRS - Campus Sertão atuaram na implantação deste Horto, assim como outros alunos indígenas da Escola Estadual Indígena de Ensino Médio Fág Mág (Pinheiro Grande) trabalharam e apoiaram na execução dessa ação. Através da realização de fotos e vídeos, foram analisadas também as expressões atuais da cultura Kaingang na conjuntura, os elementos significativos que estão guardados ao longo das gerações e apontamos os desafios de permanecer na comunidade e revitalizar com sustentabilidade os saberes e práticas Kaingang, sempre com um olhar incondicional pela natureza. Foram sistematizadas as denominações específicas da cada planta, em correspondência com seu nome científico e com o seu nome tradicional da cosmologia dual Kaingang (kam e kanhru). Conclui-se a partir dessa investigação que houve efetivamente o abandono e a falta de valorização de saberes e práticas relacionadas com a educação ambiental, pelas pressões da sociedade branca, o desejo de alguns indígenas de ser moderno e aceito na sociedade branca e pela ausência de trabalho de um educador ambiental. As iniciativas de revitalização são possíveis; o uso de plantas e alimentos tradicionais estão relacionadas com atividades que precisam ser vivenciadas primordialmente na escola, na relação com os kujà tradicionais e no desenvolvimento de projetos específicos e na motivação permanente para a responsabilidade ambiental, preservando a cultura e os costumes Kaingang que ainda são preciosos, especialmente na promoção da saúde da comunidade

Anti-Metastatic Properties of a Marine Bacterial Exopolysaccharide-Based Derivative Designed to Mimic Glycosaminoglycans

Osteosarcoma is the most frequent malignant primary bone tumor characterized by a high potency to form lung metastases. In this study, the effect of three oversulfated low molecular weight marine bacterial exopolysaccharides (OS-EPS) with different molecular weights (4, 8 and 15 kDa) were first evaluated in vitro on human and murine osteosarcoma cell lines. Different biological activities were studied: cell proliferation, cell adhesion and migration, matrix metalloproteinase expression. This in vitro study showed that only the OS-EPS 15 kDa derivative could inhibit the invasiveness of osteosarcoma cells with an inhibition rate close to 90%. Moreover, this derivative was potent to inhibit both migration and invasiveness of osteosarcoma cell lines; had no significant effect on their cell cycle; and increased slightly the expression of MMP-9, and more highly the expression of its physiological specific tissue inhibitor TIMP-1. Then, the in vivo experiments showed that the OS-EPS 15 kDa derivative had no effect on the primary osteosarcoma tumor induced by osteosarcoma cell lines but was very efficient to inhibit the establishment of lung metastases in vivo. These results can help to better understand the mechanisms of GAGs and GAG-like derivatives in the biology of the tumor cells and their interactions with the bone environment to develop new therapeutic strategies.

Efeito do Fucoidam de Fucus vesiculosus em um modelo experimental de artrite reumatóide

Rheumatoid arthritis (RA) is systemic auto imune disorder. It is caracterized by chronic inflammation of joints leading to progressive erosion of cartilage and bone. We investigated the effect of the administration of fucoidan, sulfated polysaccharides, from algae Fucus vesiculosus in the acute (6h) in zymosan-induced arthritis (AZy). Wistar rats (180-230 g) were used for all groups experimental. Non-treated animals received just intraarticular injection of 1 mg the zymosan, control group received intraarticular injection of 50 µL the saline, groups received either fucoidan of Fucus vesiculosus (15, 30, 50 or 70 mg/Kg) or parecoxib (1 mg/Kg) 1 hour after injection of zymosan. After 6 h, the articular exudates were collected for evaluation of the cell influx and nitrite (Griess reaction) release. The sinovial membranes and articular cartilages were excised for histopathological analysis and by determination of the glycosaminoglycan (GAG), respectively. ZyA led to increased NO and cell influx into the joints. Therapeutic administration of the fucoidan or parecoxib did significantly inhibited the cell influx and the synovitis, as compared to non-treated rats (p<0,05), though being able to reduced NO release. Representative agarose gel electrophoresis of the GAGs, the content of condroitin-sulphate was observed during the process. These findings suggest that the fucoidan from Fucus vesiculosus has potential anti-inflammatory activity

On the construction of new bent functions from the max-weight and min-weight functions of old bent functions

Given a bent function f (x) of n variables, its max-weight and min-weight functions are introduced as the Boolean functions f + (x) and f − (x) whose supports are the sets {a ∈ Fn2 | w( f ⊕la) = 2n−1+2 n 2 −1} and {a ∈ Fn2 | w( f ⊕la) = 2n−1−2 n 2 −1} respectively, where w( f ⊕ la) denotes the Hamming weight of the Boolean function f (x) ⊕ la(x) and la(x) is the linear function defined by a ∈ Fn2 . f + (x) and f − (x) are proved to be bent functions. Furthermore, combining the 4 minterms of 2 variables with the max-weight or min-weight functions of a 4-tuple ( f0(x), f1(x), f2(x), f3(x)) of bent functions of n variables such that f0(x) ⊕ f1(x) ⊕ f2(x) ⊕ f3(x) = 1, a bent function of n + 2 variables is obtained. A family of 4-tuples of bent functions satisfying the above condition is introduced, and finally, the number of bent functions we can construct using the method introduced in this paper are obtained. Also, our construction is compared with other constructions of bent functions.

Interface cena e tecnologia : composições cênicas mediadas

Based on the presupposition that the arts in the West always counted on resources, supports, and devices pertaining to its time context, an reflection is intended regarding the scenic compositions mediated by digital technologies do. Such technologies are inserted in the daily routine, also composing artistic experiments, thus playing a dialogical role with the art/technology intersection. Therefore, the proposal is to investigate what relationships are established in the contemporary theatrical scene from the contagion by digital technologies, aiming at establishing this parallel through a dialogue with the authors discussing the subject, and also based on the group practices having technological resources as a determinant factor in their plays. Furthermore, a reflection should be made on the scene that incorporates or is carried out in intermediatic events, analyzing how digital technologies (re)configure compositional processes of the plays by GAG Phila7, in the city of São Paulo/SP. For such, the dissertation is organized in three sections comprising four moments, to wit: brief overview of the field, contextualization, poetic analysis and synthesis. Qualitative methods are used as the methodological proposal: semi-structure interview, note and document taking (program, website, playing book, disclosure material for advertising text, photographs, and videos). Within the universe of qualitative research, it works with the epistemological perspective of the Gadamer philosophical hermeneutics. The possibilities allowed by the double virtual (Internet/web) generated a type of theater with another material basis and new forms of organization and structure, being possible to perceive that such technological advances and the arts are mutually contaminated, generating a dislocation in the logics of theatrical composition, movement beginning with the artistic vanguards, gradually intensified, thus offering new possibilities of constructions and hybridization of the of the most different possible types. Experiment ―Profanações_superfície de eventos de construção coletiva‖, idealized by Phila7 is inserted in this perspective. Object of the discussion of such research, the experiment works with possible poetics arising from the intersection with the digital technologies, aiming at identifying and problematizing the challenges from the technological evolution and expansion in a scenic context