O fogo quebra a dormência e aumenta a germinação de espécies de cerrado?

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

A germinação de espécies de Vellozia é afetada pelo fogo do cerrado?

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

O fogo quebra a dormência e aumenta a germinação de espécies de cerrado?

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

A germinação de espécies de Vellozia é afetada pelo fogo do cerrado?

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Profile of Trypanosoma cruzi Reactivity in a Population at High Risk for Endemic Pemphigus Foliaceus (Fogo Selvagem)

Fogo Selvagem (FS) is an autoimmune bullous disease with pathogenic IgG autoantibodies recognizing desmoglein 1 (Dsg1), a desmosomal glycoprotein. In certain settlements of Brazil, a high prevalence of FS (3%) is reported, suggesting environmental factors as triggers of the autoimmune response. Healthy individuals from endemic areas recognize nonpathogenic epitopes of Dsg1, and exposure to hematophagous insects is a risk factor for FS. Fogo selvagem and Chagas disease share some geographic sites, and anti-Dsg1 has been detected in Chagas patients. Indeterminate Chagas disease was identified in a Brazilian Amerindian population of high risk for FS. In counterpart, none of the FS patients living in the same geographic region showed reactivity against Trypanosoma cruzi. The profile of anti-Dsg1 antibodies showed positive results in 15 of 40 FS sera and in 33 of 150 sera from healthy individuals from endemic FS sites, and no cross-reactivity between Chagas disease and FS was observed.

An Insight into the Sialotranscriptome of Triatoma matogrossensis, a Kissing Bug Associated with Fogo Selvagem in South America

Triatoma matogrossensis is a Hemiptera that belongs to the oliveirai complex, a vector of Chagas' disease that feeds on vertebrate blood in all life stages. Hematophagous insects' salivary glands (SGs) produce potent pharmacologic compounds that counteract host hemostasis, including anticlotting, antiplatelet, and vasodilatory molecules. Exposure to T. matogrossensis was also found to be a risk factor associated with the endemic form of the autoimmune skin disease pemphigus foliaceus, which is described in the same regions where Chagas' disease is observed in Brazil. To obtain a further insight into the salivary biochemical and pharmacologic diversity of this kissing bug and to identify possible allergens that might be associated with this autoimmune disease, a cDNA library from its SGs was randomly sequenced. We present the analysis of a set of 2,230 (SG) cDNA sequences, 1,182 of which coded for proteins of a putative secretory nature.

IgG Autoantibody Response against Keratinocyte Cadherins in Endemic Pemphigus Foliaceus (Fogo Selvagem)

It is well established that autoantibodies against desmoglein 3 and desmoglein 1 (Dsg1) are relevant in the pathogenesis of pemphigus vulgaris and pemphigus foliaceus, including its endemic form fogo selvagem (FS). Isolated reports have shown that in certain patients with these diseases, autoantibodies against other desmosomal cadherins and E-cadherin may also be present. The goal of this investigation was to determine whether FS patients and normal individuals living in endemic areas possess autoantibodies against other desmosomal cadherins and E-cadherin. By testing a large number of FS and endemic control sera by ELISA, we found a consistent and specific autoantibody response against Dsg1 and other keratinocyte cadherins in these individuals, which is quite different from healthy individuals from the United States (US controls). Overall, the highest correlations among the autoantibody responses tested were in the endemic controls, followed by FS patients, and lowest in the US controls. These findings suggest that multiple, perhaps cross-reactive, keratinocyte cadherins are recognized by FS patients and endemic controls.

“L'arma più forte” La propaganda cinematografica nella guerra civile spagnola (1936-1939) Proposta di sottotitolaggio del documentario anarchico “Los Aguiluchos de la FAI por tierras de Aragón. Reportaje n° 1, Estampas de la revolución antifascista” e del documentario franchista “La liberación de Madrid”

Dal 1936 al 1939 la Spagna dovette fare i conti con gli orrori di una guerra che aveva diviso in due il paese, sia ideologicamente che geograficamente, facendogli vivere una tragedia ancora oggi tangibile nel tessuto sociale e politico della penisola iberica. Questo conflitto, che aveva suscitato l’interesse di molti, raggiunse un livello tale di sperimentazione, sia in campo militare, sia in quello civile, da essere considerato un banco di prova per la seconda guerra mondiale. Il progetto di tesi, attraverso l’analisi e il sottotitolaggio di due documentari, uno anarchico e l’altro franchista, intende presentare una ricerca che ha come focus primario lo studio della propaganda cinematografica durante il periodo della guerra civile spagnola. Il cinema che, proprio negli anni Trenta, si era definitivamente affermato anche grazie all’introduzione del sonoro, fu presto considerato un potente mezzo di comunicazione divenendo un’arma di persuasione della quale, entrambi gli schieramenti con tempistiche diverse, si servirono per indottrinare la popolazione e giustificare la propria azione militare. Il cinema, pertanto, fu messo al servizio della guerra. Nel primo capitolo di questo elaborato verrà presentato il quadro storico di riferimento con la definizione delle cause, dell’evoluzione e delle ideologie in campo durante il conflitto. Il secondo capitolo si concentrerà sull’analisi dei due sistemi di propaganda, quella repubblicana e quella nazionalista, con un’attenzione principale nei confronti della propaganda cinematografica e delle sue diverse espressioni politiche nella penisola iberica. In questo capitolo si farà, inoltre, accenno alla produzione cinematografica internazionale riferita al conflitto spagnolo durante gli anni della guerra e in quelli immediatamente successivi. Infine, nel terzo e ultimo capitolo, si prenderanno in analisi i due documentari sottotitolati (“Los Aguiluchos de la FAI por tierras de Aragón, Reportaje nº1, Estampas de la revolución antifascista” e “La Liberación de Madrid”, con la presentazione dell’analisi tecnica e contenutistica degli stessi. Per concludere, verranno indicate le strategie traduttive impiegate durante la fase di traduzione e riportati esempi concreti ad esse riferite.

Emergence of Klebsiella pneumoniae co-producing NDM-1, OXA-48, CTX-M-15, CMY-16, QnrA and ArmA in Switzerland

Extensively drug-resistant (XDR) Klebsiella pneumoniae isolates usually carry a single carbapenemase (e.g. KPC, NDM, OXA-48-like). Here we describe an XDR K. pneumoniae of sequence type 101 that was detected in the screening rectal swab of a patient transferred from the intensive care unit of a hospital located in Belgrade (Serbia) to Bern University Hospital (Switzerland). The isolate was resistant to all antibiotics with the exception of colistin [minimum inhibitory concentration] (MIC≤0.125μg/mL), tigecycline (MIC=0.5μg/mL) and fosfomycin (MIC=2μg/mL). The isolate co-possessed class B (NDM-1) and class D (OXA-48) carbapenemases, class A extended-spectrum β-lactamase (CTX-M-15), class C cephalosporinase (CMY-16), ArmA 16S rRNA methyltransferase, substitutions in GyrA and ParC, loss of OmpK35 porin, as well as other genes conferring resistance to quinolones (qnrA), tetracyclines [tet(A)], sulfonamides (sul1, sul2), trimethoprim (dfrA12, dfrA14), rifampicin (arr-1), chloramphenicol (cmlA1, floR) and streptomycin (aadA1). The patient was placed under contact isolation precautions preventing the spread of this nearly untreatable pathogen.

Franz Liszt, Arma Senkrah, Doppelbildnis

Signatur des Originals: S 36/F09109

Franz Liszt, Arma Senkrah, Doppelbildnis

Signatur des Originals: S 36/F09110

Franz Liszt, Arma Senkrah, Doppelbildnis

Signatur des Originals: S 36/F09115

Arma Senkrah, Kniestück

Signatur des Originals: S 36/F09881

Arma Senkrah, Kniestück

Signatur des Originals: S 36/F09882