Uso de Google Docs como herramienta de construcción colaborativa tomando en cuenta los estilos de aprendizaje.

Resumen basado en el de la publicación

Innovación educativa para el fomento de la alfabetización informacional en la educación superior : los portales e-COMS, ALFIN-EEES, ALFAMEDIA E IMATEC.

Se trata de un estudio sobre los distintos portales educativos enmarcados al proyecto de Espacio Europeo de Educación Superior, que se han adherido al compromiso de la Red Española de Bibliotecas Universitarias (REBIUN) de promocionar materiales docentes que ayuden a la formación del alumnado .

Estrategias de sostenibilidad y responsabilidad social en las universidades españolas : una herramienta para su evaluación.

Monográfico con el título: 'Ambientalización curricular y sostenibilidad: nuevos retos de profesionalización docente'. Resumen basado en el de la publicación

Sexting, psychological distress and dating violence among adolescents and young adults

Resumen tomado de la publicaci??n

Utilización y aplicación de la herramienta "google docs" en la docencia universitaria dentro del marco del EEES

Como consecuencia de la realización del curso 'Aplicaciones de la Web 2.0 en la Investigación y la Docencia' organizado por La Fundación General Universidad de Granada-Empresa en el curso académico 2009-2010, los autores del presente trabajo presentamos el Proyecto de Innovación Docente concedido por el Vicerrectorado para la Garantía de la calidad de la Universidad de Granada,titulado 'Utilización de la herramienta “Google Docs” en la Docencia Universitaria dentro del marco del EEES. Creemos que el proyecto tiene un diseño aplicable a cualquier asignatura de la actual Licenciatura y/o Grado de Farmacia. En este trabajo se expone la experiencia piloto llevada a cabo en la asignatura de Química Farmacéutica, incluyendo el desarrollo, objetivos, metodología, resultados y las conclusiones que se están obteniendo en el trascurso del mismo

Não sei...intervenção junto de um aluno com disfunção cognitiva em ambiência inclusiva

RESUMO: Neste trabalho pretende-se mostrar o trabalho desenvolvido num ambiente inclusivo numa turma onde se encontra um aluno com défice cognitivo ligeiro. Dele faz parte a pesquisa bibliográfica sobre a inclusão, deficiência mental e perturbações emocionais. Para identificar as diversas problemáticas da turma utilizámos a sociometria, observação naturalista entre outros. Após a recolha da informação definimos objectivos e estratégias sempre com base na inclusão. De seguida procedemos à intervenção junto do grupo nas áreas da socialização, comunicação e académica. No final realizámos a avaliação das diversas actividades de forma a percebermos se os objectivos foram alcançados. ABSTRACT: In this paper we want to show all the work we had trying to include on a regular class a student with mental retardation. To do so, we search for definitions of inclusion, mental retardation and emotional disorders to help us understand the student problem. We used the several techniques that help us find out how the students react with each other. After this we decided which objectives we wanted to achieve which this work and selected different strategies to work based on inclusion and stared working with the group. Finally we evaluated the work to see if it had helped the students or not.

Inteligência Emocional em Alunos do 8º ano : diferenças em função de variáveis sociodemográficas

A inteligência emocional tem ganho um relevo particular no domínio da psicologia, enquanto ingrediente-chave para alcançar sucesso, qualidade de relacionamento interpessoal, saúde, satisfação, bem-estar, e qualidade de vida, associados aos contextos educativos e profissionais (Nelis, Quoidbach, Mikolajczak, & Hansenne, 2009, cit. in Carvalho, 2011). Neste estudo visa-se estudar as qualidades psicométricas de um instrumento de avaliação da inteligência emocional, caracterizar a inteligência emocional, e analisar possíveis diferenças nos resultados em função de variáveis sociodemográficas. Participaram 557 alunos do 8º ano de escolaridade, 289 raparigas e 268 rapazes, entre os 11 e os 15 anos (M=13.27; DP=.583), que frequentavam escolas públicas do norte, centro, e sul de Portugal. A inteligência emocional foi avaliada através do Questionário de Inteligência Emocional de Bar-On, (Candeias & Rebocho, 2007). Em termos das qualidades psicométricas do instrumento verifica-se uma solução fatorial de 31 itens, organizados em cinco fatores, que explicam aproximadamente 50% da variância dos itens, sendo claramente identificados os fatores Humor Geral, Adaptabilidade e Interpessoal. Por sua vez, constatam-se diferenças estatisticamente significativas em função do sexo, na dimensão Intrapessoal, a favor das raparigas, e na dimensão Humor Geral a favor dos rapazes; em função da idade, na dimensão Adaptabilidade, a favor dos alunos mais novos; e, em função da localização geográfica, na dimensão Intrapessoal, a favor dos jovens do norte. Retiram-se implicações para o desenvolvimento de intervenções de aconselhamento de carreira ao longo da vida, que englobem o construto da inteligência emocional.

Estudio y análisis de la teoría de la imprevisión y su aplicabilidad en el proceso precontractual de los contratos de concesión de obra pública en el Ecuador

Esta investigación consta de dos partes perfectamente delimitadas, la primera parte consiste en estudiar, analizar y proponer los conceptos sobre delegación y concesión de obra pública. Planteados los conceptos, se realiza una diferenciación entre lo que se denomina concesión como acto administrativo y concesión como contrato administrativo, se estudia la naturaleza jurídica del contrato de concesión y cuales son sus clases, para de esta manera determinar el objetivo y la forma de extinción de la concesión de obra pública. Finalmente se determinará cual es el marco jurídico del contrato de concesión de obra pública en nuestro país y la forma como el Estado a través de la Administración Pública y Seccional hace efectiva la contratación de la concesión, es decir, del proceso precontractual y contractual de las concesiones en el país. En la segunda parte de este trabajo se enmarca doctrinariamente, que es y como se aplica la teoría de la imprevisión. Se realiza así mismo una diferenciación de esta figura jurídica con otras como: renegociación contractual, teoría del Hecho Príncipe y Fuerza Mayor. Para de esta manera saber adecuadamente en que momento podemos aplicar cada una de estas figuras en los procesos contractuales administrativos. Está visión nos dará una nueva manera de solventar los imprevistos que puedan suceder al momento de contratar una concesión de obra pública.

Modelo de gestión para el Museo Numismático del Banco Central del Ecuador

El objetivo de la presente propuesta e investigación es plantear y desarrollar un modelo de gestión para el Museo Numismático del Banco Central del Ecuador en aras de convertirlo en un espacio de desarrollo social incluyente mediante la educación y la difusión de la información numismática y económica del país. El museo numismático, ubicado en el centro histórico de Quito, tiene como objetivo actual poner en valor el patrimonio cultural numismático y notafílico ecuatoriano al difundir la historia de la moneda desde los tiempos pre-hispánicos hasta la actualidad. Pese a ello, su oferta y gestión así como su alcance social son limitados, manteniéndose de este modo, como un museo tradicional anclado en las viejas tradiciones museísticas. El presente estudio inicia con un abordaje teórico-conceptual donde abordamos los conceptos desarrollo social, capital socio-cultural, nueva museología y gestión social proveniente de distintos organismos nacionales e internacionales y autores de amplia trayectoria. Esta matriz conceptual resulta trascendental, pues de ello depende el desarrollo socio-educativo de la nueva propuesta que se pretende implementar en el museo, la cual consiste en ofrecer elementos pedagógicos y socio-culturales para que la comunidad se empodere y sienta como suyo el museo numismático. Posteriormente se efectúa un diagnóstico FODA de la actual gestión del museo, en base a la anterior información, elaboramos en el tercer capítulo una propuesta de gestión socio-educativa. Esta propuesta se inicia con el planteamiento de objetivos, la visión/misión y los principios rectores, las nuevas dependencias administrativas. Con este plan, que parte con un cambio de adentro hacia afuera, pretendemos que el museo se convierta en una institución potencialmente atractiva para la ciudadanía y el país, dado sus aportes para el conocimiento integral y el desarrollo socio-cultural.

Modulation of endothelial cell KCa3.1 Channels during endothelium-derived hyperpolarizing factor signaling in mesenteric resistance arteries

Arterial hyperpolarization to acetylcholine (ACh) reflects coactivation of KCa3.1 (IKCa) channels and KCa2.3 (SKCa) channels in the endothelium that transfers through myoendothelial gap junctions and diffusible factor(s) to affect smooth muscle relaxation (endothelium-derived hyperpolarizing factor [EDHF] response). However, ACh can differentially activate KCa3.1 and KCa2.3 channels, and we investigated the mechanisms responsible in rat mesenteric arteries. KCa3.1 channel input to EDHF hyperpolarization was enhanced by reducing external [Ca2+]o but blocked either with forskolin to activate protein kinase A or by limiting smooth muscle [Ca2+]i increases stimulated by phenylephrine depolarization. Imaging [Ca2+]i within the endothelial cell projections forming myoendothelial gap junctions revealed increases in cytoplasmic [Ca2+]i during endothelial stimulation with ACh that were unaffected by simultaneous increases in muscle [Ca2+]i evoked by phenylephrine. If gap junctions were uncoupled, KCa3.1 channels became the predominant input to EDHF hyperpolarization, and relaxation was inhibited with ouabain, implicating a crucial link through Na+/K+-ATPase. There was no evidence for an equivalent link through KCa2.3 channels nor between these channels and the putative EDHF pathway involving natriuretic peptide receptor-C. Reconstruction of confocal z-stack images from pressurized arteries revealed KCa2.3 immunostain at endothelial cell borders, including endothelial cell projections, whereas KCa3.1 channels and Na+/K+-ATPase {alpha}2/{alpha}3 subunits were highly concentrated in endothelial cell projections and adjacent to myoendothelial gap junctions. Thus, extracellular [Ca2+]o appears to modify KCa3.1 channel activity through a protein kinase A-dependent mechanism independent of changes in endothelial [Ca2+]i. The resulting hyperpolarization links to arterial relaxation largely through Na+/K+-ATPase, possibly reflecting K+ acting as an EDHF. In contrast, KCa2.3 hyperpolarization appears mainly to affect relaxation through myoendothelial gap junctions. Overall, these data suggest that K+ and myoendothelial coupling evoke EDHF-mediated relaxation through distinct, definable pathways.

Nitric oxide suppresses cerebral vasomotion by sGC-independent effects on ryanodine receptors and voltage-gated calcium channels

Background/Aims: In cerebral arteries, nitric oxide (NO) release plays a key role in suppressing vasomotion. Our aim was to establish the pathways affected by NO in rat middle cerebral arteries. Methods: In isolated segments of artery, isometric tension and simultaneous measurements of either smooth muscle membrane potential or intracellular [Ca 2+ ] ([Ca 2+ ] SMC ) changes were recorded. Results: In the absence of L -NAME, asynchronous propagating Ca 2+ waves were recorded that were sensitive to block with ryanodine, but not nifedipine. L -NAME stimulated pronounced vasomotion and synchronous Ca 2+ oscillations with close temporal coupling between membrane potential, tone and [Ca 2+ ] SMC . If nifedipine was applied together with L -NAME, [Ca 2+ ] SMC decreased and synchronous Ca 2+ oscillations were lost, but asynchronous propagating Ca 2+ waves persisted. Vasomotion was similarly evoked by either iberiotoxin, or by ryanodine, and to a lesser extent by ODQ. Exogenous application of NONOate stimulated endothelium-independent hyperpolarization and relaxation of either L -NAME-induced or spontaneous arterial tone. NO-evoked hyperpolarization involved activation of BK Ca channels via ryanodine receptors (RYRs), with little involvement of sGC. Further, in whole cell mode, NO inhibited current through L-type voltage-gated Ca 2+ channels (VGCC), which was independent of both voltage and sGC. Conclusion: NO exerts sGC-independent actions at RYRs and at VGCC, both of which normally suppress cerebral artery myogenic tone.

Evidence for involvement of both IKCa and SKCa channels in hyperpolarizing responses of the rat middle cerebral artery

Endothelium-derived hyperpolarizing factor responses in the rat middle cerebral artery are blocked by inhibiting IKCa channels alone, contrasting with peripheral vessels where block of both IKCa and SKCa is required. As the contribution of IKCa and SKCa to endothelium-dependent hyperpolarization differs in peripheral arteries, depending on the level of arterial constriction, we investigated the possibility that SKCa might contribute to equivalent hyperpolarization in cerebral arteries under certain conditions. METHODS: Rat middle cerebral arteries (approximately 175 microm) were mounted in a wire myograph. The effect of KCa channel blockers on endothelium-dependent responses to the protease-activated receptor 2 agonist, SLIGRL (20 micromol/L), were then assessed as simultaneous changes in tension and membrane potential. These data were correlated with the distribution of arterial KCa channels revealed with immunohistochemistry. RESULTS: SLIGRL hyperpolarized and relaxed cerebral arteries undergoing variable levels of stretch-induced tone. The relaxation was unaffected by specific inhibitors of IKCa (TRAM-34, 1 micromol/L) or SKCa (apamin, 50 nmol/L) alone or in combination. In contrast, the associated smooth-muscle hyperpolarization was inhibited, but only with these blockers in combination. Blocking nitric oxide synthase (NOS) or guanylyl cyclase evoked smooth-muscle depolarization and constriction, with both hyperpolarization and relaxation to SLIGRL being abolished by TRAM-34 alone, whereas apamin had no effect. Immunolabeling showed SKCa and IKCa within the endothelium. CONCLUSIONS: In the absence of NO, IKCa underpins endothelium-dependent hyperpolarization and relaxation in cerebral arteries. However, when NOS is active SKCa contributes to hyperpolarization, whatever the extent of background contraction. These changes may have relevance in vascular disease states where NO release is compromised and when the levels of SKCa expression may be altered.

Possible role for K+ in endothelium-derived hyperpolarizing factor–linked dilatation in rat middle cerebral artery

Background and Purpose— Endothelium-derived hyperpolarizing factor (EDHF) and K+ are vasodilators in the cerebral circulation. Recently, K+ has been suggested to contribute to EDHF-mediated responses in peripheral vessels. The EDHF response to the protease-activated receptor 2 ligand SLIGRL was characterized in cerebral arteries and used to assess whether K+ contributes as an EDHF. Methods— Rat middle cerebral arteries were mounted in either a wire or pressure myograph. Concentration-response curves to SLIGRL and K+ were constructed in the presence and absence of a variety of blocking agents. In some experiments, changes in tension and smooth muscle cell membrane potential were recorded simultaneously. Results— SLIGRL (0.02 to 20 μmol/L) stimulated concentration and endothelium-dependent relaxation. In the presence of NG-nitro-L-arginine methyl ester, relaxation to SLIGRL was associated with hyperpolarization and sensitivity to a specific inhibitor of IKCa, 1-[(2-chlorophenyl)diphenylmethyl]-1H-pyrazole (1μmol/L), reflecting activation of EDHF. Combined inhibition of KIR with Ba2+ (30μmol/L) and Na+/K+-ATPase with ouabain (1 μmol/L) markedly attenuated the relaxation to EDHF. Raising extracellular [K+] to 15 mmol/L also stimulated smooth muscle relaxation and hyperpolarization, which was also attenuated by combined application of Ba2+ and ouabain. Conclusions— SLIGRL evokes EDHF-mediated relaxation in the rat middle cerebral artery, underpinned by hyperpolarization of the smooth muscle. The profile of blockade of EDHF-mediated hyperpolarization and relaxation supports a pivotal role for IKCa channels. Furthermore, similar inhibition of responses to EDHF and exogenous K+ with Ba2+ and ouabain suggests that K+ may contribute as an EDHF in the middle cerebral artery.

Association between Mediterranean and Nordic diet scores and changes in weight and waist circumference: influence of FTO and TCF7L2 loci

BACKGROUND: Several studies have shown that adherence to the Mediterranean Diet measured by using the Mediterranean diet score (MDS) is associated with lower obesity risk. The newly proposed Nordic Diet could hold similar beneficial effects. Because of the increasing focus on the interaction between diet and genetic predisposition to adiposity, studies should consider both diet and genetics. OBJECTIVE: We investigated whether FTO rs9939609 and TCF7L2 rs7903146 modified the association between the MDS and Nordic diet score (NDS) and changes in weight (Δweight), waist circumference (ΔWC), and waist circumference adjusted for body mass index (BMI) (ΔWCBMI). DESIGN: We conducted a case-cohort study with a median follow-up of 6.8 y that included 11,048 participants from 5 European countries; 5552 of these subjects were cases defined as individuals with the greatest degree of unexplained weight gain during follow-up. A randomly selected subcohort included 6548 participants, including 5496 noncases. Cases and noncases were compared in analyses by using logistic regression. Continuous traits (ie, Δweight, ΔWC, and ΔWCBMI) were analyzed by using linear regression models in the random subcohort. Interactions were tested by including interaction terms in models. RESULTS: A higher MDS was significantly inversely associated with case status (OR: 0.98; 95% CI: 0.96, 1.00), ΔWC (β = -0.010 cm/y; 95% CI: -0.020, -0.001 cm/y), and ΔWCBMI (β = -0.008; 95% CI:-0.015, -0.001) per 1-point increment but not Δweight (P = 0.53). The NDS was not significantly associated with any outcome. There was a borderline significant interaction between the MDS and TCF7L2 rs7903146 on weight gain (P = 0.05), which suggested a beneficial effect of the MDS only in subjects who carried 1 or 2 risk alleles. FTO did not modify observed associations. CONCLUSIONS: A high MDS is associated with a lower ΔWC and ΔWCBMI, regardless of FTO and TCF7L2 risk alleles. For Δweight, findings were less clear, but the effect may depend on the TCF7L2 rs7903146 variant. The NDS was not associated with anthropometric changes during follow-up.