A mouse peritonitis model for the study of glycopeptide efficacy in GISA infections

In recent years, the emergence of Staphylococcus aureus strains with reduced susceptibility to glycopeptides has raised considerable concern. We studied the efficacy of vancomycin and teicoplanin, as well as cloxacillin and cefotaxime, against the infection caused by four S. aureus strains with different glycopeptide and β-lactam susceptibilities (strains A, B, C, and D; MICs for vancomycin of 1, 2, 4, and 8 µg/ml respectively), using a modified model of mouse peritonitis. This optimized model appeared to be straightforward and reproducible, and was able to detect low differences in bacterial killing between antibiotics and also between different S. aureus strains. Bactericidal activities in peritoneal fluid for vancomycin, teicoplanin, cloxacillin, and cefotaxime decreased from -2.98, -2.36, -3.22, and -3.57 log10 cfu/ml, respectively, in infection by strain A (MICs for vancomycin and cloxacillin of 1 and 0.38 µg/ml, respectively) to -1.22, -0.65, -1.04, and +0.24 in peritonitis due to strain D (MICs for vancomycin and cloxacillin of 8 and 1,024 µg/ml). Our data confirm the superiority of β-lactams against methicillin-susceptible S. aureus and show that bactericidal activity of glycopeptides decreases significantly with slight increases in MICs; this finding suggests a reduced efficacy of glycopeptides in the treatment of serious glycopeptide-intermediate S. aureus infections

Complications of guided surgery and immediate loading in oral implantology: a report of 12 cases

Objectives: The growing interest in minimally invasive surgery, together with the possibility of fitting prostheses with immediate function, have led to the development of software capable of planning and manufacturing a surgical guide and prosthesis that can be placed upon conclusion of the implant surgery step. The present study evaluates the surgical and prosthetic complications of implant treatment with the guided surgery technique, together with patient comfort during and after treatment. Patients and methods: A retrospective observational study was made of 19 patients with partially or totally edentulous upper and/or lower maxillae, involving the placement of a total of 122 implants. All cases were planned and operated upon with the guided surgery technique. Results: A total of 122 implants were placed in 14 males and 5 females. The intraoperative surgical complications comprised a lack of primary stability, while the postoperative complications consisted of infections and a lack of implant osteointegration. Ten implants failed. The prosthetic complications in turn comprised loosening of the provisional prosthesis screws, prosthesis tooth fracture, and a lack of passive fit of the immediate prosthesis. The degree of patient satisfaction was evaluated using a verbal scale. Conclusions: Implant restoration with the guided surgery technique and immediate functional loading is a predictable procedure, provided patient selection and the surgical technique are adequate, affording lesser postoperative morbidity and increased patient satisfaction thanks to the immediate restoration of esthetics and function

Oral implant rehabilitation in a patient with Moebius syndrome

Introduction: Moebius syndrome is a rare congenital disorder characterized by unilateral or bilateral involvement of the sixth and seventh cranial nerves, resulting in a lack of facial expression and eye movements. These patients suffer a series of oral manifestations that may complicate their dental treatment, such as facial and tongue muscle weakness, uncontrolled salivation secondary to defi cient lip sealing, micrognathia, microstomia, bifi d uvula, gothic and fi ssured palate, fi ssured tongue, and glossoptosis. The underlying etiology remains unclear, though vascular problems during embryogenesis appear to be involved. Clinical case: We report the case of a woman with Moebius syndrome and total edentulism. Eight years ago she underwent complete oral rehabilitation with the placement of two implants in each dental arch. Discussion: Moebius syndrome has still an unknown etiology, although it is related to disorders during pregnancy. This kind of patient can be rehabilitated using oral implants.

Ciclo vital y posicion sistematica de Jaagiella alpicola Vischer (Chlorophyceae)

Jaagiella alpicola fue aislada de suelos del Cap Norfeu (Gerona) mediante cultivos de enriquecimiento. Las células vegetativas son uninucleadas y contienen un cloroplasto parietal sin pirenoide. La reproducción asexual se lleva a cabo por bipartición y mediante acinetos y esporas móviles biflageladas. Las zoosporas se desarrollan directamente, después de su liberación, dando lugar a un talo heterótrico. El estudio de la división de las células vegetativas, mediante MET, ha revelado que se forma un huso mitótico metacéntrico en la telofase. Todas las características observadas indican que J. alpicola debe situarse en el orden Pleurastroles (Pleurastrophyceae).

Desarrollo de la materia Proyectos. Grado de Comunicación Audiovisual. Universitat de Barcelona

El objetivo del presente trabajo es presentar la propuesta de desarrollo de la materia Proyectos del Grado de Comunicación Audiovisual de la Universidad de Barcelona, que incluye las asignaturas Proyectos I y Proyectos II. Ambas asignaturas son especialmente idóneas para trabajar las competencias transversales del grado, dado que el objetivo de la materia a la que pertenecen es integrar las competencias adquiridas en el conjunto de asignaturas cursadas por los alumnos hasta este momento, poniendo en relación los diferente lenguajes (escrito, oral, audiovisual y multimedia). Todo esto permite que el estudiante adquiera una visión integral y transversal. El presente trabajo reflexiona sobre los mecanismos que permitan al profesorado diseñar de forma colaborativa pautas y estrategias de enseñanza-aprendizaje; los modos de evaluación de las competencias de estas asignaturas, y todos aquellos aspectos claves que deben recoger los planes docentes. Materias como la de Proyectos suponen un reto en la actividad docente, al requerir del trabajo interdisciplinar e integrador de las áreas de conocimiento implicadas y de los docentes vinculados, al tiempo que facilitan la generación de puentes entre el ámbito académico y profesional.

A framework for the analysis of CLIL lecturers’ discourse from a genre perspective

Internationalization strategies and the European Space of Higher Education are causing a growing interest in English medium instruction (EMI). University linguistic and internationalization policies are attempting to provide lectures with the required training and education. Linguists can supply not only the knowledge of the language but the knowledge about language which may enable lecturers to increase their academic language competence autonomously. This paper presents a framework for the analysis of lecturers’ discourse to trigger reflection about the linguistic needs in CLIL/EMI contexts.

Screening premorbid metabolic syndrome in community pharmacies: a cross-sectional descriptive study

Background: Premorbid metabolic syndrome (pre-MetS) is a cluster of cardiometabolic risk factors characterised by central obesity, elevated fasting glucose, atherogenic dyslipidaemia and hypertension without established cardiovascular disease or diabetes. Community pharmacies are in an excellent position to develop screening programmes because of their direct contact with the population. The main aim of the study was to determine the prevalence of pre-MetS in people who visited community pharmacies for measurement of any of its five risk factors to detect the presence of other risk factors. The secondary aims were to study the presence of other cardiovascular risk factors and determine patients" cardiovascular risk. Methods: Cross-sectional, descriptive, multicentre study. Patients meeting selection criteria aged between 18 and 65 years who visited participating community pharmacies to check any of five pre-MetS diagnostic factors were included. The study involved 23 community pharmacies in Catalonia (Spain). Detection criteria for pre-MetS were based on the WHO proposal following IDF and AHA/NHBI consensus. Cardiovascular risk (CVR) was calculated by Regicor and Score methods. Other variables studied were smoking habit, physical activity, body mass index (BMI), and pharmacological treatment of dyslipidemia and hypertension. The data were collected and analysed with the SPSS programme. Comparisons of variables were carried out using the Student"s T-test, Chi-Squared test or ANOVA test. Level of significance was 5% (0.05). Results: The overall prevalence of pre-MetS was 21.9% [95% CI 18.7-25.2]. It was more prevalent in men, 25.5% [95% CI 22.1-28.9], than in women, 18.6% [95% CI 15.5-21.7], and distribution increased with age. The most common risk factors were high blood pressure and abdominal obesity. About 70% of people with pre-MetS were sedentary and over 85% had a BMI ≥25 Kg/m2 . Some 22.4% had two metabolic criteria and 27.2% of patients with pre-MetS had no previous diagnosis. Conclusions: The prevalence of pre-MetS in our study (21.9%) was similar to that found in other studies carried out in Primary Care in Spain. The results of this study confirm emergent cardiometabolic risk factors such as hypertension, obesity and physical inactivity. Our study highlights the strategic role of the community pharmacy in the detection of pre-MetS in the apparently healthy population.

Estudio cualitativo sobre factores psicosociales de riesgo en profesionales de enfermería (Catalunya-España).

Peer-reviewed

Protocolo de intervención psicosocial de la Asociación de Expertos en Psicosociologia Aplicada - AEPA.

Peer-reviewed

Salud ocupacional e intervención psicosocial

Peer-reviewed

CTCPS-MAC - Batería Para el Estudio de las Condiciones de Trabajo de Carácter Psicosocial

El estudio de las condiciones de trabajo de carácter psicosocial CTCPS-MAC consta de 75 ítems que agrupan cuatro dimensiones, que se pueden evaluar por separado y un total de 14 factores. Tiene como intención la evaluación de la percepción que tiene la población trabajadora de las condiciones de trabajo de carácter psicosocial en su propio entorno laboral así como de los factores individuales y los síntomas subjetivos y alteraciones de la salud.

Protocolo de intervención psicosocial de la Asociación de Expertos en Psicosociología Aplicada AEPA

Se presenta la versión revisada y actualizada por los autores del protocolo de intervención psicosocial de la Asociación de Expertos en Psicosociología Aplicada - AEPA, correspondiente al trabajo efectuado entre los años 2008 y 2009.

Factores Psicosociales y Organizaciones Saludables en tiempos de crisis

Presentación del Modelo de empresa saludable y sostenible y del Modelo para la intervención psicosocial laboral.

Gestión para una empresa saludable: ganamos todos

Peer-reviewed

Inventario de Violencia y Acoso Psicológico en el Trabajo (IVAPT-E-R)

Peer-reviewed