Development and validation of an UV spectrophotometric method for determination of gatifloxacin in tablets

A simple, sensitive and accurate spectrophotometric method was developed for the assay of gatifloxacin in raw material and tablets. Validation of the method yielded good results concerning range, linearity, precision and accuracy. The absorbance was measured at 287 nm for gatifloxacin tablet solutions. The linearity range was found to be 4.0-14.0 μg/mL for gatifloxacin. It was also found that the excipients in the commercial tablets did not interfere with the method.

Determination of flutamide in tablets by high-performance liquid chromatography

Flutamide is a potent antiandrogen used for the treatment of prostatic cancer. A simple, sensitive and accurate high-performance liquid Chromatographic (HPLC) method is presented for quantitative determination of flutamide in tablets, using a reversed-phase technique and UV detection at 240 nm. The isocratic elution was used to quantify the analyte. The samples were chromatographed on Luna-C18 column and the mobile phase was 0.05 M phosphate buffer pH 4.0 - acetonitrile (50:50, v/v). The method was linear between 2.9 - 11.6 mg L -1. Over the tested concentration range the intra-day relative standard deviation for replicate analysis in tablets ranged from 0.44 to 0.78%. It was also found that the excipients in the commercial tablets did not interfere with the method.

High-performance liquid chromatography determination of praziquantel in tablets and raw materials

A specific and sensitive high-performance liquid chromatographic method was developed for the assay of praziquantel in raw materials and tablets. It was also found that the excipients in the commercial tablet preparation did not interfere with the assay in the wavelenght selected. The method validation yielded good results and included the range, linearity, precision, accuracy, specificity and recovery.

Back to school with tablets embedded in digital desks

A digital-desk pilot program, named One Laptop Per Child (OPLC), in Brazil uses a unique display design to provide an interactive interface developed to enhance education and minimize ergonomic concerns. The one-to-one computer strategy as proposed by Nicholas Negroponte is a way of circumventing the tragedy of the locked computer lab because it gives children full access to computers anytime. The OLPC program has focused on a solution that minimizes power consumption, which also limits the display's maximum size and processor performance because the LCD backlights are responsible for a significant part of the power consumption in laptops. The government has also developed a new type of low-cost tablet that is based on a resistive principle. High transparencies can be obtained in the 90% range in the tablet, while robustness is guaranteed by the outstanding tribological characteristics of Sn02 on glass.

Jornalismo e cultura de consumo: uma análise da Revista Rolling Stone - Brasil

Pós-graduação em Comunicação - FAAC

Uso de tablets como ferramenta facilitadora em projetos de inclusão digital de idosos

Pós-graduação em Design - FAAC

Provocações brasileiras: a imprensa contracultural made in Brazil : coluna Underground (1969-1971), Flor do mal (1971) & a Rolling Stone brasileira (1972-1973)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Mineralogy and chemistry of the green stone artifacts (muiraquitãs) of the museums of the Brazilian State of Pará

Os muiraquitãs foram considerados de proveniência asiática ou, também, como peças esculpidas pelas lendárias mulheres guerreiras, as Amazonas. São peças, hoje, muito raras, encontradas em alguns acervos de Museus. Estudos mineralógicos e químicos de 23 peças do acervo dos Museus de Gemas e do Encontro em Belém, Brasil, mostraram que os muiraquitãs podem ser constituídos, tanto de quartzo, como de albita, ou microclínio, pirofilita, variscita, anortita e tremolita (equivalente ao jade nefrítico), minerais frequentes em formações geológicas do Brasil. No entanto quatro peças são constituídas de jadeíta, ou seja, em jade jadeítico, raro e desconhecido na Amazônia e Brasil. A constatação da presença desse mineral reacende a discussão em torno da origem mineralógica dos muiraquitãs encontrados na Amazônia. Essa origem, antes da atual descoberta, era defendida como amazônica, devido à ausência de jade jadeítico nas peças pesquisadas e pelo fato de jadeíta não ter sido encontrada no Brasil, mas na América Central e na Ásia.

Multivariate Development and Validation of a Stability-Indicating HPLC Method for the Determination of Glimepiride in Tablets

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Quantification of Doxycycline Hyclate in Tablets by HPLC-UV Method

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

A novel automated alternating current biosusceptometry method to characterization of controlled-release magnetic floating tablets of metronidazole

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Rolling Stone Brasil: aspectos de interatividade

The purpose of the present dissertation is to show the interactivity connections featured in a cultural journalism magazine's website through direct observation of its presented structure. The website chosen as object of study is Rolling Stone Brasil, April 2010 being the point of reference for analysis. Methodological support for such study has been culled from theoretical works on the principles that are necessary for the development of sampling in the observed structure. For this, are employed of concepts and strategies predicated by authors in the field of communications with emphasis on digital means is aplicated. The research indicates that the tools adopted in the website's structure comprise a potential of interactivity between the parties involved in the communication chain, and that the content therein produced may be considered as direct content of a web journalism structure

Imprensa alternativa e contracultura: o jornal brasileiro Rolling Stone de 1972

The present monograph is a historical research of one of the brazilian newspapers in a journalistic heterogeneous effervescence, referring to the proliferation of vehicles on alternative libertarians of the 60/70. The project gives visibility to the Rolling Stone newspaper as the document that disproved their own relevancy in the viability of the music production and counterculture inspired by North America, developing the repercussion of the new behavior of young flower power in the country. The personality of those who were in the journalistic team, the production schema, editorial and proposed tariffs would be in total congruency with the countercultural movement

Ergonomia de tablets em uso ocupacional: atividade visual e biomecânica postural sob a influência de ofuscamentos reflexivos causados pela iluminação

Pós-graduação em Design - FAAC

Use of the probability of stone formation (PSF) score to assess stone forming risk and treatment response in a cohort of Brazilian stone formers

Introduction: The aim was to confirm that PSF (probability of stone formation) changed appropriately following medical therapy on recurrent stone formers.Materials and Methods: Data were collected on 26 Brazilian stone-formers. A baseline 24-hour urine collection was performed prior to treatment. Details of the medical treatment initiated for stone-disease were recorded. A PSF calculation was performed on the 24 hour urine sample using the 7 urinary parameters required: voided volume, oxalate, calcium, urate, pH, citrate and magnesium. A repeat 24-hour urine sample was performed for PSF calculation after treatment. Comparison was made between the PSF scores before and during treatment.Results: At baseline, 20 of the 26 patients (77%) had a high PSF score (> 0.5). Of the 26 patients, 17 (65%) showed an overall reduction in their PSF profiles with a medical treatment regimen. Eleven patients (42%) changed from a high risk (PSF > 0.5) to a low risk (PSF < 0.5) and 6 patients reduced their risk score but did not change risk category. Six (23%) patients remained in a high risk category (> 0.5) during both assessments.Conclusions: The PSF score reduced following medical treatment in the majority of patients in this cohort.