Development and validation of an UV spectrophotometric method for determination of gatifloxacin in tablets
| Contribuinte(s) |
Universidade Estadual Paulista (UNESP) |
|---|---|
| Data(s) |
27/05/2014
27/05/2014
01/04/2005
|
| Resumo |
A simple, sensitive and accurate spectrophotometric method was developed for the assay of gatifloxacin in raw material and tablets. Validation of the method yielded good results concerning range, linearity, precision and accuracy. The absorbance was measured at 287 nm for gatifloxacin tablet solutions. The linearity range was found to be 4.0-14.0 μg/mL for gatifloxacin. It was also found that the excipients in the commercial tablets did not interfere with the method. |
| Formato |
263-264 |
| Identificador |
http://www.ingentaconnect.com/content/govi/pharmaz/2005/00000060/00000004/art00005 Pharmazie, v. 60, n. 4, p. 263-264, 2005. 0031-7144 http://hdl.handle.net/11449/68192 WOS:000228532600005 2-s2.0-17644362688 |
| Idioma(s) |
eng |
| Relação |
Pharmazie |
| Direitos |
openAccess |
| Palavras-Chave | #excipient #gatifloxacin #quinoline derived antiinfective agent #accuracy #analytic method #aqueous solution #calibration #correlation coefficient #drug determination #linear regression analysis #reproducibility #statistical analysis #tablet formulation #ultraviolet spectrophotometry #validation process #Anti-Infective Agents #Calibration #Fluoroquinolones #Reference Standards #Reproducibility of Results #Spectrophotometry, Ultraviolet #Tablets |
| Tipo |
info:eu-repo/semantics/article |
