O impacto do excesso de gordura corporal sobre a remodelação óssea de adolescentes

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Co-Product Prices May Be Nearing Seasonal Low

The supply of corn milling co-products from ethanol production has increased rapidly over the last several years. Based on United States Department of Agriculture (USDA) projections of corn ground for ethanol production, approximately 38 million tons of distillers grains would have been produced in the 2009-10 marketing year, with 40 million tons projected for the 2010-11 marketing year. While supply has grown, so too has demand from both domestic and international users. Cattle feeders in particular have found wet distillers grains plus solubles (WDGS), modified wet distillers grains plus solubles (MWDGS) and dried distillers grains plus solubles (DDGS) to be excellent feedstuffs that can lower cost of gain through performance efficiencies and lower ingredient costs. United States swine and poultry producers have also increasingly adopted DDGS in rations in response to higher corn prices, while international shipments of DDGS have also grown.

Nutritional strategies to control mycotoxin damages in swine

Mycotoxins are contaminants of agricultural products both in the field and during storage and can enter the food chain through contaminated cereals and foods (milk, meat, and eggs) obtained from animals fed mycotoxin contaminated feeds. Mycotoxins are genotoxic carcinogens that cause health and economic problems. Ochratoxin A and fumonisin B1 have been classified by the International Agency for Research on Cancer in 1993, as “possibly carcinogenic to humans” (class 2B). To control mycotoxins induced damages, different strategies have been developed to reduce the growth of mycotoxigenic fungi as well as to decontaminate and/or detoxify mycotoxin contaminated foods and animal feeds. Critical points, target for these strategies, are: prevention of mycotoxin contamination, detoxification of mycotoxins already present in food and feed, inhibition of mycotoxin absorption in the gastrointestinal tract, reduce mycotoxin induced damages when absorption occurs. Decontamination processes, as indicate by FAO, needs the following requisites to reduce toxic and economic impact of mycotoxins: it must destroy, inactivate, or remove mycotoxins; it must not produce or leave toxic and/or carcinogenic/mutagenic residues in the final products or in food products obtained from animals fed decontaminated feed; it must be capable of destroying fungal spores and mycelium in order to avoiding mycotoxin formation under favorable conditions; it should not adversely affect desirable physical and sensory properties of the feedstuff; it has to be technically and economically feasible. One important approach to the prevention of mycotoxicosis in livestock is the addition in the diets of the non-nutritionally adsorbents that bind mycotoxins preventing the absorption in the gastrointestinal tract. Activated carbons, hydrated sodium calcium aluminosilicate (HSCAS), zeolites, bentonites, and certain clays, are the most studied adsorbent and they possess a high affinity for mycotoxins. In recent years, there has been increasing interest on the hypothesis that the absorption in consumed food can be inhibited by microorganisms in the gastrointestinal tract. Numerous investigators showed that some dairy strains of LAB and bifidobacteria were able to bind aflatoxins effectively. There is a strong need for prevention of the mycotoxin-induced damages once the toxin is ingested. Nutritional approaches, such as supplementation of nutrients, food components, or additives with protective effects against mycotoxin toxicity are assuming increasing interest. Since mycotoxins have been known to produce damages by increasing oxidative stress, the protective properties of antioxidant substances have been extensively investigated. Purpose of the present study was to investigate in vitro and in vivo, strategies to counteract mycotoxin threat particularly in swine husbandry. The Ussing chambers technique was applied in the present study that for the first time to investigate in vitro the permeability of OTA and FB1 through rat intestinal mucosa. Results showed that OTA and FB1 were not absorbed from rat small intestine mucosa. Since in vivo absorption of both mycotoxins normally occurs, it is evident that in these experimental conditions Ussing diffusion chambers were not able to assess the intestinal permeability of OTA and FB1. A large number of LAB strains isolated from feces and different gastrointestinal tract regions of pigs and poultry were screened for their ability to remove OTA, FB1, and DON from bacterial medium. Results of this in vitro study showed low efficacy of isolated LAB strains to reduce OTA, FB1, and DON from bacterial medium. An in vivo trial in rats was performed to evaluate the effects of in-feed supplementation of a LAB strain, Pediococcus pentosaceus FBB61, to counteract the toxic effects induced by exposure to OTA contaminated diets. The study allows to conclude that feed supplementation with P. pentosaceus FBB61 ameliorates the oxidative status in liver, and lowers OTA induced oxidative damage in liver and kidney if diet was contaminated by OTA. This P. pentosaceus FBB61 feature joined to its bactericidal activity against Gram positive bacteria and its ability to modulate gut microflora balance in pigs, encourage additional in vivo experiments in order to better understand the potential role of P. pentosaceus FBB61 as probiotic for farm animals and humans. In the present study, in vivo trial on weaned piglets fed FB1 allow to conclude that feeding of 7.32 ppm of FB1 for 6 weeks did not impair growth performance. Deoxynivalenol contamination of feeds was evaluated in an in vivo trial on weaned piglets. The comparison between growth parameters of piglets fed DON contaminated diet and contaminated diet supplemented with the commercial product did not reach the significance level but piglet growth performances were numerically improved when the commercial product was added to DON contaminated diet. Further studies are needed to improve knowledge on mycotoxins intestinal absorption, mechanism for their detoxification in feeds and foods, and nutritional strategies to reduce mycotoxins induced damages in animals and humans. The multifactorial approach acting on each of the various steps could be a promising strategy to counteract mycotoxins damages.

Evaluation of bone strength: microtomographic tecniques

This thesis is a part of a larger study about the characterization of mechanical and histomorphometrical properties of bone. The main objects of this study were the bone tissue properties and its resistance to mechanical loads. Moreover, the knowledge about the equipment selected to carry out the analyses, the micro-computed tomography (micro-CT), was improved. Particular attention was given to the reliability over time of the measuring instrument. In order to understand the main characteristics of bone mechanical properties a study of the skeletal, the bones of which it is composed and biological principles that drive their formation and remodelling, was necessary. This study has led to the definition of two macro-classes describing the main components responsible for the resistance to fracture of bone: quantity and quality of bone. The study of bone quantity is the current clinical standard measure for so-called bone densitometry, and research studies have amply demonstrated that the amount of tissue is correlated with its mechanical properties of elasticity and fracture. However, the models presented in the literature, including information on the mere quantity of tissue, have often been limited in describing the mechanical behaviour. Recent investigations have underlined that also the bone-structure and the tissue-mineralization play an important role in the mechanical characterization of bone tissue. For this reason in this thesis the class defined as bone quality was mainly studied, splitting it into two sub-classes of bone structure and tissue quality. A study on bone structure was designed to identify which structural parameters, among the several presented in the literature, could be integrated with the information about quantity, in order to better describe the mechanical properties of bone. In this way, it was also possible to analyse the iteration between structure and function. It has been known for long that bone tissue is capable of remodeling and changing its internal structure according to loads, but the dynamics of these changes are still being analysed. This part of the study was aimed to identify the parameters that could quantify the structural changes of bone tissue during the development of a given disease: osteoarthritis. A study on tissue quality would have to be divided into different classes, which would require a scale of analysis not suitable for the micro-CT. For this reason the study was focused only on the mineralization of the tissue, highlighting the difference between bone density and tissue density, working in a context where there is still an ongoing scientific debate.

Extended-spectrum cephalosporin-resistant Gram-negative organisms in livestock: an emerging problem for human health?

Escherichia coli, Salmonella spp. and Acinetobacter spp. are important human pathogens. Serious infections due to these organisms are usually treated with extended-spectrum cephalosporins (ESCs). However, in the past two decades we have faced a rapid increasing of infections and colonization caused by ESC-resistant (ESC-R) isolates due to production of extended-spectrum-β-lactamases (ESBLs), plasmid-mediated AmpCs (pAmpCs) and/or carbapenemase enzymes. This situation limits drastically our therapeutic armamentarium and puts under peril the human health. Animals are considered as potential reservoirs of multidrug-resistant (MDR) Gram-negative organisms. The massive and indiscriminate use of antibiotics in veterinary medicine has contributed to the selection of ESC-R E. coli, ESC-R Salmonella spp. and, to less extent, MDR Acinetobacter spp. among animals, food, and environment. This complex scenario is responsible for the expansion of these MDR organisms which may have life-threatening clinical significance. Nowadays, the prevalence of food-producing animals carrying ESC-R E. coli and ESC-R Salmonella (especially those producing CTX-M-type ESBLs and the CMY-2 pAmpC) has reached worryingly high values. More recently, the appearance of carbapenem-resistant isolates (i.e., VIM-1-producing Enterobacteriaceae and NDM-1 or OXA-23-producing Acinetobacter spp.) in livestock has even drawn greater concerns. In this review, we describe the aspects related to the spread of the above MDR organisms among pigs, cattle, and poultry, focusing on epidemiology, molecular mechanisms of resistance, impact of antibiotic use, and strategies to contain the overall problem. The link and the impact of ESC-R organisms of livestock origin for the human scenario are also discussed.

Minimising pain in farm animals: the 3S approach - 'Suppress, Substitute, Soothe'

Recently, the French National Institute for Agricultural Research appointed an expert committee to review the issue of pain in food-producing farm animals. To minimise pain, the authors developed a '3S' approach accounting for 'Suppress, Substitute and Soothe' by analogy with the '3Rs' approach of 'Reduction, Refinement and Replacement' applied in the context of animal experimentation. Thus, when addressing the matter of pain, the following steps and solutions could be assessed, in the light of their feasibility (technical constraints, logistics and regulations), acceptability (societal and financial aspects) and availability. The first solution is to suppress any source of pain that brings no obvious advantage to the animals or the producers, as well as sources of pain for which potential benefits are largely exceeded by the negative effects. For instance, tail docking of cattle has recently been eliminated. Genetic selection on the basis of resistance criteria (as e.g. for lameness in cattle and poultry) or reduction of undesirable traits (e.g. boar taint in pigs) may also reduce painful conditions or procedures. The second solution is to substitute a technique causing pain by another less-painful method. For example, if dehorning cattle is unavoidable, it is preferable to perform it at a very young age, cauterising the horn bud. Animal management and constraint systems should be designed to reduce the risk for injury and bruising. Lastly, in situations where pain is known to be present, because of animal management procedures such as dehorning or castration, or because of pathology, for example lameness, systemic or local pharmacological treatments should be used to soothe pain. These treatments should take into account the duration of pain, which, in the case of some management procedures or diseases, may persist for longer periods. The administration of pain medication may require the intervention of veterinarians, but exemptions exist where breeders are allowed to use local anaesthesia (e.g. castration and dehorning in Switzerland). Extension of such exemptions, national or European legislation on pain management, or the introduction of animal welfare codes by retailers into their meat products may help further developments. In addition, veterinarians and farmers should be given the necessary tools and information to take into account animal pain in their management decisions.

Foodborne illness - An age old problem requiring contemporary solutions

Foodborne illness has always been with us, and food safety is an increasingly important public health issue affecting populations worldwide. In the United States of America, foodborne illness strikes millions of people and kills thousands annually, costing our economy billions of dollars in medical care expense and lost productivity. The nature of food and foodborne illness has changed dramatically in the last century. The regulatory systems have evolved to better assure a safe food supply. The food production industry has invested heavily to meet regulatory requirement and to improve the safety of their products. Educational efforts have increased public awareness of safe food handling practices, empowering consumers to fulfill their food safety role. Despite the advances made, none of the Healthy People 2010 targets for reduction of foodborne pathogens has been reached. There is no single solution to eliminating pathogen contamination from all classes of food products. However, irradiation seems especially suited for certain higher-risk foods such as meat and poultry and its use should advance the goal of reducing foodborne illness by minimizing the presence of pathogenic organisms in the food supply. This technology has been studied extensively for over 50 years. The Food and Drug Administration has determined that food irradiation is safe for use as approved by the Agency. It is time to take action to educate consumers about the benefits of food irradiation. Consumer demand will compel industry to meet demand by investing in facilities and processes to assure a consistent supply of irradiated food products. ^

Assessment of cancer incidence in Titus County, Texas, 1977--1984

The purpose of this study was to determine the incidence of cancer in Titus County, Texas, through the identification of all cases of cancer that occurred in residents of the county during the period from 1977 to 1984. Data gathered from Texas Cancer Registry, hospital records, and death certificates were analyzed with regard to anatomic site, race, sex, age, city of residence, and place of birth. Adjustment of incidence rates by sex and race allowed comparisons with U.S. rates provided by the Surveillance, Epidemiology, and End Results Program (SEER).^ Seven hundred sixty-six (766) cancer cases were identified for the eight year period during 171,536 person-years of observation. In whites, statistically significant standardized incidence ratios (SIR) were found for leukemia (males SIR = 2.70 and females SIR = 2.26), melanoma (males SIR = 1.90 and females SIR = 2.25), lung (males SIR = 1.45) and for multiple myeloma (both sexes combined SIR = 1.86). In blacks, significant excess numbers of cases were found for Hodgkin's disease (males SIR = 8.33 and females SIR = 13.3) and for esophagus and bone considering both sexes together (SIR = 2.68 and 12.54, respectively). Rates for blacks were based on a small population and therefore unstable. A statistically significant excess number of cases for all sites combined was found in Mount Pleasant residents (age-adjusted incidence rate = 563.6 per 100,000 per year).^ A review of possible environmental risk factors in the area: hazardous waste disposal site, lignite deposits, and petrochemical and poultry industries are presented. A need for further epidemiological and environmental studies to identify etiological factors that could be responsible for the excess number of leukemia cases are recommended. For melanoma, a public health educational program to teach the population methods of protection from sun exposure is also suggested. ^

Proyecto de Desarrollo Inteligente Departamento Burruyacu - Tucumán Propuesta integrada con distintos actores institucionales a partir de mesa de gestión territorial

El presente proyecto 'Desarrollo Inteligente del Departamento Burruyacu - Tucumán' elaborado en base a un diagnostico participativo que dio como resultado, 'ex ante', el poder identificar una realidad con una problemática de territorio, basada en las siguientes dimensiones: a) Ambientales y de infraestructura, b) Organizacionales y económicos, c) De competitividad, en las economías locales, d) Educativos y de articulación institucional. Las posibilidades de avanzar en proyectos que contemplen solo las inherentes a inversiones productivas no tenían un origen genuino en el espíritu emprendedor de los habitantes y productores de la zona Este del Departamento (Gobernador Piedrabuena, Gobernador Garmendia y 7 de Abril) pero si se pudo identificar un importante sector de potenciales productores porcinos, bovinos de carne y avícolas, - cadenas no relevantes en la zona -, más un gran número de productores agrícolas -pequeños y medianos- en plena actividad, pero con nulas experiencias en producción pecuaria. Con esto, la provincia a través de sus herramientas de políticas publicas, puso la mirada en la concepción de estos nuevos enfoques de desarrollo territorial, con proyectos que posibilitarán desarrollar con equidad y sustentabilidad dicha zona profundizando los 4 ejes estratégicos. El concepto de desarrollo de los territorios, incluidos en el ámbito rural, se ha asociado tradicionalmente a la búsqueda de viabilidad de las zonas más alejadas, poco accesibles y que sufren distintas formas de marginalidad. Sin embargo, la ruralidad ha cambiado de manera significativa. Entre los cambios identificados por diferentes autores (Sarraceno, 1994; Pérez, 2001; Echeverri y Ribeiro, 2002), se destacan: a) el incremento en la importancia de las actividades no agrícolas como generadoras de empleo e ingresos para la población rural; b) la creciente integración de los espacios urbanos y rurales; c) la importancia de integrar las preocupaciones por la gestión sostenible del ambiente y de los recursos naturales; d) las transformaciones en la institucionalidad rural; e) el reconocimiento de la importancia de nuevos actores sociales; f) las nuevas y mayores expectativas de los consumidores y de los mercados; g) el papel de las nuevas tecnologías de información y comunicación, h)la persistencia de la pobreza rural y la desigualdad, i) la persistencia de brechas regionales y sectoriales

Proyecto de Desarrollo Inteligente Departamento Burruyacu - Tucumán Propuesta integrada con distintos actores institucionales a partir de mesa de gestión territorial

El presente proyecto 'Desarrollo Inteligente del Departamento Burruyacu - Tucumán' elaborado en base a un diagnostico participativo que dio como resultado, 'ex ante', el poder identificar una realidad con una problemática de territorio, basada en las siguientes dimensiones: a) Ambientales y de infraestructura, b) Organizacionales y económicos, c) De competitividad, en las economías locales, d) Educativos y de articulación institucional. Las posibilidades de avanzar en proyectos que contemplen solo las inherentes a inversiones productivas no tenían un origen genuino en el espíritu emprendedor de los habitantes y productores de la zona Este del Departamento (Gobernador Piedrabuena, Gobernador Garmendia y 7 de Abril) pero si se pudo identificar un importante sector de potenciales productores porcinos, bovinos de carne y avícolas, - cadenas no relevantes en la zona -, más un gran número de productores agrícolas -pequeños y medianos- en plena actividad, pero con nulas experiencias en producción pecuaria. Con esto, la provincia a través de sus herramientas de políticas publicas, puso la mirada en la concepción de estos nuevos enfoques de desarrollo territorial, con proyectos que posibilitarán desarrollar con equidad y sustentabilidad dicha zona profundizando los 4 ejes estratégicos. El concepto de desarrollo de los territorios, incluidos en el ámbito rural, se ha asociado tradicionalmente a la búsqueda de viabilidad de las zonas más alejadas, poco accesibles y que sufren distintas formas de marginalidad. Sin embargo, la ruralidad ha cambiado de manera significativa. Entre los cambios identificados por diferentes autores (Sarraceno, 1994; Pérez, 2001; Echeverri y Ribeiro, 2002), se destacan: a) el incremento en la importancia de las actividades no agrícolas como generadoras de empleo e ingresos para la población rural; b) la creciente integración de los espacios urbanos y rurales; c) la importancia de integrar las preocupaciones por la gestión sostenible del ambiente y de los recursos naturales; d) las transformaciones en la institucionalidad rural; e) el reconocimiento de la importancia de nuevos actores sociales; f) las nuevas y mayores expectativas de los consumidores y de los mercados; g) el papel de las nuevas tecnologías de información y comunicación, h)la persistencia de la pobreza rural y la desigualdad, i) la persistencia de brechas regionales y sectoriales

Proyecto de Desarrollo Inteligente Departamento Burruyacu - Tucumán Propuesta integrada con distintos actores institucionales a partir de mesa de gestión territorial

El presente proyecto 'Desarrollo Inteligente del Departamento Burruyacu - Tucumán' elaborado en base a un diagnostico participativo que dio como resultado, 'ex ante', el poder identificar una realidad con una problemática de territorio, basada en las siguientes dimensiones: a) Ambientales y de infraestructura, b) Organizacionales y económicos, c) De competitividad, en las economías locales, d) Educativos y de articulación institucional. Las posibilidades de avanzar en proyectos que contemplen solo las inherentes a inversiones productivas no tenían un origen genuino en el espíritu emprendedor de los habitantes y productores de la zona Este del Departamento (Gobernador Piedrabuena, Gobernador Garmendia y 7 de Abril) pero si se pudo identificar un importante sector de potenciales productores porcinos, bovinos de carne y avícolas, - cadenas no relevantes en la zona -, más un gran número de productores agrícolas -pequeños y medianos- en plena actividad, pero con nulas experiencias en producción pecuaria. Con esto, la provincia a través de sus herramientas de políticas publicas, puso la mirada en la concepción de estos nuevos enfoques de desarrollo territorial, con proyectos que posibilitarán desarrollar con equidad y sustentabilidad dicha zona profundizando los 4 ejes estratégicos. El concepto de desarrollo de los territorios, incluidos en el ámbito rural, se ha asociado tradicionalmente a la búsqueda de viabilidad de las zonas más alejadas, poco accesibles y que sufren distintas formas de marginalidad. Sin embargo, la ruralidad ha cambiado de manera significativa. Entre los cambios identificados por diferentes autores (Sarraceno, 1994; Pérez, 2001; Echeverri y Ribeiro, 2002), se destacan: a) el incremento en la importancia de las actividades no agrícolas como generadoras de empleo e ingresos para la población rural; b) la creciente integración de los espacios urbanos y rurales; c) la importancia de integrar las preocupaciones por la gestión sostenible del ambiente y de los recursos naturales; d) las transformaciones en la institucionalidad rural; e) el reconocimiento de la importancia de nuevos actores sociales; f) las nuevas y mayores expectativas de los consumidores y de los mercados; g) el papel de las nuevas tecnologías de información y comunicación, h)la persistencia de la pobreza rural y la desigualdad, i) la persistencia de brechas regionales y sectoriales

Estudo da durabilidade de painéis de partículas de bagaço de cana de açúcar e resina poliuretana a base de óleo de mamona para aplicação na construção civil

O presente trabalho tem por objetivo avaliar o desempenho físico-mecânico e a durabilidade de painéis de partículas de bagaço de cana-de-açúcar com resina bicomponente a base de mamona (BCP) e compará-los com painéis de partículas de madeira comerciais (Medium Density Particleboard - MDP). Os painéis de bagaço de cana de açúcar foram fabricados com um teor de resina poliuretana a base de óleo de maona de 15%. O desempenho físico e mecânico dos painéis particulados foi analisado com base nas prescrições dos documentos normativos vigentes. Ambos os materiais foram revestidos superficialmente com resina poliuretana bicomponente à base de óleo de mamona. Avaliou-se a influência do tratamento das bordas na deterioração e no desempenho dos painéis. O acompanhamento das propriedades físico-mecânicas foi realizado antes e após os ensaios de envelhecimento por exposição natural durante 3, 6 e 12 meses, envelhecimento acelerado e de intemperismo artificial. Foi feita a avaliação, da suscetibilidade ao crescimento gerada pelo ataque de fungos emboloradores e apodrecedores nos materiais durante o envelhecimento natural e no ensaio acelerado. Foi realizada a análise colorimétrica para a identificação de mudanças de cor e brilho nos materiais após os ensaios de deterioração. Foram utilizadas as técnicas de densitometria de raios X, espectroscopia por infravermelho próximo (NIR). Os resultados obtidos indicaram a selagem lateral permitiu avaliar a superfície exposta do material permitindo a entrada da água pela superfície avaliando o efeito dos agentes de deterioração. A porcentagem de retenção para o Módulo de ruptura após o ensaio de envelhecimento por imersão em agua e secagem (APA D1) foi de 87% e 3% para BCP e MDP sem revestimento respectivamente e de 90% e 3% para BCP e MDP com revestimento. A porcentagem de retenção das propriedades mecânicas em ambos os submetidos à exposição natural diminuiu em função do tempo. Entretanto o porcentagem de retenção para os materiais BCP e MDP com revestimento superficial foi de 76% e 60% para MOR. A exposição natural mostrou que os fungos emboloradores foram predominantes em ambos os materiais. Ambos os materiais com revestimento superficial apresentaram entre 1-10% de colonização com um 70% de probabilidade. Revestimento de resina de óleo de mamona reduz o crescimento de fungos em ambos os materiais no ensaio acelerado. O perfil de densitometria permitiu analisar o processo de fabricação dos painéis e permitiu identificar a deterioração gradativa do ambos os materiais após os ensaios de envelhecimento. A intepretação mediante a analise de componentes principais (ACP) na aplicação do NIR comportou a classificação das características relacionadas a cada ensaio de deterioração de ambos os materiais sem revestimento superficial. Com base nos resultados deste trabalho, foram propostas contribuições para ajustes de metodologias para a avaliação da durabilidade e do desempenho físico e mecânico dos painéis particulados, tendo em vista a sua viabilidade técnica, em sistemas construtivos da construção civil.

Animal production quarterly statistics 1/2 1980

"I: Monthly statistics on meat; II: Monthly statistics on eggs and poultry; III: Monthly statistics on milk and milk products; External trade and 'Eurostat balance-sheets': meat, eggs and milk products; V: Supply balance-sheets — Survey."

Eggs.

Blank pages for "My own recipes" ([607-608])

Proceedings Seventh National Symposium on Food Processing Wastes, April 7-9, 1976, Atlanta, Georgia.

Mode of access: Internet.