A lecture before the Boston Young men's society, on the subject of lotteries. Delivered March 12, 1833.

Mode of access: Internet.

A list of the members of the Dublin-Society for the Improvement of Husbandry and Other Useful Arts for the year 1733.

Goldsmiths'-Kress no. 07065.14, suppl.

A discourse pronounced at the request of the Essex historical society, on the 18th of September, 1828, in commemoration of the first settlement of Salem, in the state of Massachusetts. Pub. at the request of the society.

Mode of access: Internet.

Christian duty to emigrants: a sermon delivered before the Boston society for the prevention of pauperism, at the Old South church in Boston, May 9, 1852.

Cover title: A sermon delivered before the ... society ...

Yearbook of the National Society for the Study of Education.

Published: New York, NY : Teachers College, Columbia University, 2010-

Transactions for the Rhode Island Society for the Encouragement of Domestic Industry in the year...

No more published after 1874.

Japan Society for the Promotion of Science Postdoctoral Research Fellowships /

Mode of access: Internet.

Address to the Rhode-Island Society for the Encouragement of Domestick Industry, delivered at Pawtuxet, October 17, 1822.

Mode of access: Internet.

Address to the Rhode-Island Society for the Encouragement of Domestic Industry, delivered at Pawtuxet, October 16th, 1822 /

Mode of access: Internet.

An Aging society : meeting the needs of the elderly while responding to rising federal costs : report to the Chairman, Subcommittee on Intergovernmental Relations and Human Resources, Committee on Government Operations, House of Representatives /

"B-223880"--P. [1].

Determinants of civil society influence:the case of international development and humanitarian NGOs in the Czech Republic and Hungary

Accession to the EU has had ambiguous effects on civil society organizations (CSOs) in the East Central European countries. A general observation is that accession has not led to the systematic empowerment of CSOs in terms of growing influence on national policy making. This article investigates the determinants of successful CSO advocacy by looking at international development and humanitarian NGOs (NGDOs) in the Czech Republic and Hungary. Reforms in the past decade in the Czech Republic have created an international development policy largely in line with NGDO interests, while Hungary’s ministry of foreign affairs seems to have been unresponsive to reform demands from civil society. The article argues that there is clear evidence of NGDO influence in the Czech Republic on international development policy, which is because of the fact that Czech NGDOs have been able solve problems of collective actions, while the Hungarian NGDO sector remains fragmented. They also have relatively stronger capacities, can rely on greater public support and can thus present more legitimate demands towards their government.

A discourse delivered before the Rhode-Island Historical Society, on the evening of Thursday February 1, 1849. Published at the request of the Society.

"Sketch of the progress of historical science."

Hydroxylases regulate intestinal fibrosis through the suppression of ERK mediated TGF-β1 signaling

Fibrosis is a complication of chronic inflammatory disorders such as inflammatory bowel disease (IBD), a condition which has limited therapeutic options and often requires surgical intervention. Pharmacologic inhibition of oxygen-sensing prolyl hydroxylases (PHD), which confer oxygen-sensitivity upon the hypoxia inducible factor (HIF) pathway, has recently been shown to have therapeutic potential in colitis, although the mechanisms involved remain unclear. Here, we investigated the impact of hydroxylase inhibition on inflammation-driven fibrosis in a murine colitis model. Mice exposed to dextran sodium sulfate followed by period of recovery developed intestinal fibrosis characterized by alterations in the pattern of collagen deposition and infiltration of activated fibroblasts. Treatment with the hydroxylase inhibitor dimethyloxalylglycine (DMOG) ameliorated fibrosis. TGF-β1 is a key regulator of fibrosis which acts through the activation of fibroblasts. Hydroxylase inhibition reduced TGF-β1-induced expression of fibrotic markers in cultured fibroblasts suggesting a direct role for hydroxylases in TGF-β1 signalling. This was at least in part due to inhibition of non-canonical activation of extracellular signal-regulated kinase (ERK) signalling. In summary, pharmacologic hydroxylase inhibition ameliorates intestinal fibrosis, through suppression of TGF-β1-dependent ERK activation in fibroblasts. We hypothesize that in addition to previously reported immunosupressive effects, hydroxylase inhibitors independently suppress pro-fibrotic pathways