972 resultados para Polypeptide Kalata B1


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Título del congreso: 'Aprender español en Noruega: por qué y para qué'. Incluye vídeo MP4

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Se presenta una actividad didáctica dirigida a alumnos con nivel específico A2-B1 (MCER) y con una duración estimada de 90 minutos. Los objetivos son: practicar la competencia lectora de textos literarios; sensibilizar a los alumnos sobre el funcionamiento de un texto literario; aumentar el conocimiento y manejo de textos literarios; reflexionar sobre las diferencias de interpretación causadas por el factor cultural; y reforzar la expresión oral .

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"ALCE de Lyon"

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"ALCE de Lyon"

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Trabajo fin de m??ster (CIESE Comillas-Universidad de Cantabria, 2012)

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Conjunto de materiales elaborados por los auxiliares de conversaci??n de Francia durante el curso 2013/2014. Recoge material did??ctico para el nivel B1 que los profesores interesados pueden descargar . La tipolog??a de los materiales es muy variada, como tambi??n lo son sus autores, y por ello las posibilidades de su utilizaci??n son diversas. Junto con los contenidos ling????sticos se asocian otros orientados a la convivencia en las aulas o al mejor conocimiento de la cultura espa??ola e hispanoamericana.

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Existe una versi??n en espa??ol, con el t??tulo "Nivel B1 de Euskara en Educaci??n Primaria. Informe general. Febrero 2007"

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Esta publicaci??n de la serie de propuestas curriculares para la ense??anza, el aprendizaje y la evaluaci??n de la lengua de signos espa??ola recoge las especificaciones: objetivos, contenidos, orientaciones metodol??gicas y procedimientos de evaluaci??n para el Nivel B1, que se corresponde con el hom??nimo de la escala del MCER. Con ella se describe, en l??nea de continuidad con la entrega anterior (Niveles A1 y A2), lo que supone que los alumnos alcancen un nuevo estadio en la estructura del curr??culo de la lengua de signos espa??ola.

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Seeds of Avicennia alba BI. matured at high moisture content and were sensitive to desiccation: no seeds survived desiccation below 35% moisture content. The effect on survival of a factorial combination of five moist storage treatments (fresh seeds in a polyethylene bag, open with water sprayed over regularly, mixed with sand at 10% moisture content, mixed with moist paddy hulls, or naked seeds mixed with sand at 10% moisture content) and three temperatures (28-30degreesC, 17degreesC and 8-10degreesC) was investigated. In addition, seeds were mixed with sand at 5% moisture content and stored at 17degreesC in order to determine the effect of sand moisture content on seed moisture content and viability during storage. Avicennia alba showed recalcitrant seed storage behaviour, but 75% of the seeds remained viable after four months' moist (45-47% moisture content) storage in 10% moisture content sand at 17degreesC.

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Repair of the mature mammalian myocardium following injury is impaired by the inability of the majority of cardiomyocytes to undergo cell division. We show that overexpression of the cyclin B1-CDC2 (cell division cycle 2 kinase) complex re-initiates cell division in adult cardiomyocytes. Thus strategies targeting the cyclin B1-CDC2 complex might re-initiate cell division in mature cardiomyocytes in vivo and facilitate myocardial regeneration following injury.

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Amyloid fibrils are typically rigid, unbrariched structures with diameters of similar to 10 nm and lengths up to several micrometres, and are associated with more than 20 diseases including Alzheimer's disease and type II diabetes. Insulin is a small, predominantly alpha-helical protein consisting of 51 residues in two disulfide-linked polypeptide chains that readily assembles into amyloid fibrils under conditions of low PH and elevated temperature. We demonstrate here that both the A-chain and the B-chain of insulin are capable of forming amyloid fibrils in isolation under similar conditions, with fibrillar morphologies that differ from those composed of intact insulin. Both the A-chain and B-chain fibrils were found to be able to cross-seed the fibrillization of the parent protein, although these reactions were substantially less efficient than self-seeding with fibrils composed of full-length insulin. In both cases, the cross-seeded fibrils were morphologically distinct from the seeding, material, but shared common characteristics with typical insulin fibrils, including a very similar helical repeat. The broader distribution of heights of the cross-seeded fibrils compared to typical insulin fibrils, however, indicates that their underling protofilament hierarchy may be subtly different. In addition, and remarkably in view of this seeding behavior, the soluble forms of the A-chain and B-chain peptides were found to be capable of inhibiting insulin fibril formation. Studies using mass spectrometry suggest that this behavior might be attributable to complex formation between insulin and the A-chain and B-chain peptides. The finding that the same chemical form of a polypeptide chain in different physical states can either stimulate or inhibit the conversion of a protein into amyloid fibrils sheds new light on the mechanisms underlying fibril formation, fibril strain propagation and amyloid disease initiation and progression. (c) 2006 Elsevier Ltd. All rights reserved.

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The aim was to determine in 32 healthy young men from northern and southern Europe whether differences in the secretion of insulin and glucose-dependent insulinotropic polypeptide (GIP) might explain these findings through the actions of these hormones on lipoprotein lipase. In a randomized, single-blind, crossover study the effects of 2 test meals of identical macronutrient composition but different saturated fatty acid (SFA) and monounsaturated fatty acid (MUFA) contents were investigated on postprandial GIP, insulin, the ratio of incremental triacylglycerol to apolipoprotein B-48 (a marker of chylomicron size), and the activity of postheparin lipases. Fasting and postprandial GIP concentrations and postheparin hepatic lipase (HL) activities were higher in the southern Europeans (P<0.001 and P<0.02, respectively). Lipoprotein lipase activity after the SFA-rich meal was higher in the northern Europeans (P<0.01). HL activity 9 h after the SFA-rich meal and the area under the curve (AUC) for the postprandial insulin response correlated with the AUC for the postprandial GIP response (r=0.44 (P<0.04) and r=0.46 (P<0.05), respectively). There were no significant differences in chylomicron size between the 2 groups for either meal, but when the groups were combined there was a difference in chylomicron size between the SFA- and MUFA-rich meals (P<0.05), which could be due to the formation of larger chylomicrons after the MUFA-rich meal. The significantly higher GIP and insulin responses and HL activities in southern Europeans may provide an explanation for a previous report of attenuated postprandial triacylglycerol and apolipoprotein B-48 responses in them.