Andrea Goldenbaum: Innovationsmanagement in Schulen. Eine empirische Untersuchung zur Implementation eines Sozialen Lernprogramms. Wiesbaden: Springer VS 2012 (320 S.) [Rezension]

Rezension von: Andrea Goldenbaum: Innovationsmanagement in Schulen. Eine empirische Untersuchung zur Implementation eines Sozialen Lernprogramms. Wiesbaden: Springer VS 2012 (320 S.; ISBN 978- 3-531-19424-0)

"Storia di Ugho da Vernia" de Andrea da Barberino: Edición crítica

En la “Storia di Ugho da Vernia de Andrea da Barberino: Edición crítica” se ha querido replantear el estudio de un escritor toscano a caballo entre los siglos XIV y XV cuya producción tuvo mucha difusión y aceptación en su tiempo, y del que algunas de sus obras siguen interesando en nuestros días. Para ello el objetivo principal ha sido el de esbozar un análisis de una de sus obras más peculiares, la Storia di Ugho da Vernia, peculiar porque en ella se reúnen aspectos importantes de las chansons de geste francesas, de las novelas caballerescas y de los libros de caballerías; especialmente de la chanson se puede destacar que el protagonista pertenece al linaje de Garin de Monglane le fier o narbonnais que, como sus parientes, lucha contra los sarracenos y es un buen vasallo ―no se rebela ante la absurda petición de su señor de ir al infierno e incluso soporta las burlas de este―; de los libros de caballería podrían proceder los seres irreales contra los que se enfrenta como dragones, serpientes enormes, gigantes, etc., a los que indefectiblemente vence y, por último, de las novelas caballerescas, la pátina de realidad que se desprende del modo de narrar y de algunos lugares evocados en los que se desarrolla la acción, como Santiago de Compostela, Roma, Jerusalén, Calabria, Grecia, etc., donde los tres primeros son los principales puntos de peregrinación occidentales. En lo que concierne al texto, se ha tratado de ofrecer una edición crítica que dé inicio a posteriores investigaciones desde las distintas perspectivas de análisis que el texto exige; hay que tener en cuenta que en 1882 F. Zambrini y A. Bacchi della Lega editaron la obra, pero se limitaron a transcribirla, como ellos mismos comentan en la introducción; es más, siguieron la copia que había transcrito un bibliotecario de la Biblioteca Magliabechiana. En 1968 se realizó una reimpresión del texto sin aportar nada nuevo y en 2013 se ha incorporado a la red siguiendo los formatos MLA y APA, cuya diferencia radica en la forma de presentar los textos...

Tra linguistica e narrazione: Il segreto di Pietramala di Andrea Moro

Il segreto di Pietramala (La nave di Teseo, 2018) è il primo romanzo di Andrea Moro e si caratterizza per la discussione di teorie linguistiche all’interno di una veste narrativa. A partire dai contenuti del romanzo, i cinque capitoli in cui si articola l’elaborato propongono una riflessione sul ruolo che la linguistica riveste e sul modo in cui emerge nella narrazione, sui principi di analogia e anomalia e sul rapporto tra sintassi e cervello, sull’acquisizione del linguaggio e sull’ipotesi di una lingua primigenia, sulla linguistica come scienza empirica e sulla natura della sintassi, sull’impossibilità di stilare graduatorie di valore delle lingue.

Inclusività di genere nel linguaggio: proposta di traduzione gender-neutral della poesia Good Light di Andrea Gibson

Una delle domande che ha da sempre profondamente interessato l’ambito degli studi linguistici è se sia la lingua a riflettere la società dei parlanti o se sia la società dei parlanti a essere plasmata dalla lingua. O, ancora, se esse non siano direttamente coinvolte in una dinamica di reciproca influenza che permette loro di modellarsi a vicenda. Qualunque sia la risposta, certo è che negli ultimi tempi la società ha cambiato radicalmente il proprio modo di pensare e approcciarsi ad alcune tematiche, quali, ad esempio, la questione dell’identità di genere e dei diritti delle comunità LGBTQ+. È dunque inevitabile che il linguaggio che ha a che fare con tale ambito della società rimanga inalterato e non subisca cambiamenti in termini di usi e caratteristiche. L’obiettivo di queste pagine è quello di esplorare le problematiche legate all’uso improprio del linguaggio in relazione alle identità di genere non binarie, facendo riferimento in particolare al testo poetico e alla sua traduzione e fornendo, infine, un esempio pratico di come poche accortezze possano rendere il linguaggio totalmente inclusivo e più accomodante per coloro che attraversano i confini del binarismo di genere.

[yoga And The Promotion Of Health].

The scope of this paper is to analyze the self-declared symptoms and state of well-being of participants in the Yoga and Promotion of Health program, which consisted of hatha yoga lessons. It includes body exercises and breathing techniques, as well as ethical and philosophical content, administered to two groups of lecturers, workers and students of a public university in the State of São Paulo from August to December 2011 and March to June 2012. The participants filled out the adapted version of the Measure Yourself Medical Outcome Profile form at the beginning and end of the program. Of the 20 participants in Group 1, eight filled out the form and half of them reported the improvement of self-declared symptoms; as regards the state of well being, three of them felt they had improved. In Group 2, which also had 20 participants, nine completed the program and all of them reported improvements of self-declared symptoms and well-being. In conclusion, yoga is a mind-body practice which exerts an important therapeutic effect on most practitioners and also promotes health for the majority of them, expanding their capacity of self perception and self care. However, it should be noted that it doesn't achieve the same positive effect for all practitioners as some yoga traditions advocate.

Phosphate Regulated Proteins Of Xanthomonas Citri Subsp. Citri: A Proteomic Approach.

Xanthomonas citri subsp. citri (X. citri) is the causative agent of the citrus canker, a disease that affects several citrus plants in Brazil and across the world. Although many studies have demonstrated the importance of genes for infection and pathogenesis in this bacterium, there are no data related to phosphate uptake and assimilation pathways. To identify the proteins that are involved in the phosphate response, we performed a proteomic analysis of X. citri extracts after growth in three culture media with different phosphate concentrations. Using mass spectrometry and bioinformatics analysis, we showed that X. citri conserved orthologous genes from Pho regulon in Escherichia coli, including the two-component system PhoR/PhoB, ATP binding cassette (ABC transporter) Pst for phosphate uptake, and the alkaline phosphatase PhoA. Analysis performed under phosphate starvation provided evidence of the relevance of the Pst system for phosphate uptake, as well as both periplasmic binding proteins, PhoX and PstS, which were formed in high abundance. The results from this study are the first evidence of the Pho regulon activation in X. citri and bring new insights for studies related to the bacterial metabolism and physiology. Biological significance Using proteomics and bioinformatics analysis we showed for the first time that the phytopathogenic bacterium X. citri conserves a set of proteins that belong to the Pho regulon, which are induced during phosphate starvation. The most relevant in terms of conservation and up-regulation were the periplasmic-binding proteins PstS and PhoX from the ABC transporter PstSBAC for phosphate, the two-component system composed by PhoR/PhoB and the alkaline phosphatase PhoA.

Homozygous Inactivating Mutation In Nanos3 In Two Sisters With Primary Ovarian Insufficiency.

Despite the increasing understanding of female reproduction, the molecular diagnosis of primary ovarian insufficiency (POI) is seldom obtained. The RNA-binding protein NANOS3 poses as an interesting candidate gene for POI since members of the Nanos family have an evolutionarily conserved function in germ cell development and maintenance by repressing apoptosis. We performed mutational analysis of NANOS3 in a cohort of 85 Brazilian women with familial or isolated POI, presenting with primary or secondary amenorrhea, and in ethnically-matched control women. A homozygous p.Glu120Lys mutation in NANOS3 was identified in two sisters with primary amenorrhea. The substituted amino acid is located within the second C2HC motif in the conserved zinc finger domain of NANOS3 and in silico molecular modelling suggests destabilization of protein-RNA interaction. In vitro analyses of apoptosis through flow cytometry and confocal microscopy show that NANOS3 capacity to prevent apoptosis was impaired by this mutation. The identification of an inactivating missense mutation in NANOS3 suggests a mechanism for POI involving increased primordial germ cells (PGCs) apoptosis during embryonic cell migration and highlights the importance of NANOS proteins in human ovarian biology.

Effect Of Aloe Vera Application On The Content And Molecular Arrangement Of Glycosaminoglycans During Calcaneal Tendon Healing.

Although several treatments for tendon lesions have been proposed, successful tendon repair remains a great challenge for orthopedics, especially considering the high incidence of re-rupture of injured tendons. Our aim was to evaluate the pharmacological potential of Aloe vera on the content and arrangement of glycosaminoglycans (GAGs) during tendon healing, which was based on the effectiveness of A. vera on collagen organization previously observed by our group. In rats, a partial calcaneal tendon transection was performed with subsequent topical A. vera application at the injury site. The tendons were treated with A. vera ointment for 7 days and excised on the 7(th) , 14(th) , or 21(st) day post-surgery. Control rats received ointment without A. vera. A higher content of GAGs and a lower amount of dermatan sulfate were detected in the A. vera-treated group on the 14(th) day compared with the control. Also at 14 days post-surgery, a lower dichroic ratio in toluidine blue stained sections was observed in A. vera-treated tendons compared with the control. No differences were observed in the chondroitin-6-sulfate and TGF-β1 levels between the groups, and higher amount of non-collagenous proteins was detected in the A. vera-treated group on the 21(st) day, compared with the control group. No differences were observed in the number of fibroblasts, inflammatory cells and blood vessels between the groups. The application of A. vera during tendon healing modified the arrangement of GAGs and increased the content of GAGs and non-collagenous proteins.

Changes In The Connective Tissue Sheath Of Wistar Rat Nerve With Aging.

The alterations due to aging in the peripheral nerves can affect the physiology of these structures. Thus, the purpose of the present study was to describe the activity of the MMP-2 and MMP-9, as well as the structure and composition of the extracellular matrix of the rat sciatic nerve during maturation and aging. Our results have shown that the extracellular matrix of the sciatic nerve of 30-, 180- and 730-day-old Wistar rats present ultrastructural, morphometrical and biochemical changes during aging. The perineurium was the structure most affected by age, as evidenced by a decrease in thickness and in collagen fibril content. Cytochemical analysis detected proteoglycans in the basal membrane of Schwann cells and around perineural cells, as well as on the collagen fibrils of the perineurium and endoneurium at all ages. Biochemical analyses showed that the quantity of non-collagenous proteins was higher in 730-day-old animals compared to other ages, while the uronic acid content was higher in 30-day-old animals. Morphometrical analysis detected greater numbers of myelinated fibers and increased myelin thickness in 180-day-old animals. Zymography analysis detected greater amounts and activity of MMP-2 and MMP-9 in 180- and 730-day-old animals compared to younger rats. In conclusion, our results showed changes in the structural organization and composition of extracellular matrix of the sciatic nerve during aging, such as increase in the non-collagenous protein content and higher MMP-2 and MMP-9 activity, decrease in uronic acid concentration and in collagen fibril content in the perineurium, as well as degeneration of nerve fibers.