Fractal spatialities

This paper argues for the use of ‘fractals’ in theorising sociospatial relations. From a realist position, a nonmathematical but nonmetaphoric and descriptive view of ‘fractals’ is advanced. Insights from the natural sciences are combined with insights on the position of the observer from Luhmann and notions of assemblages and repetitions from Deleuze. It is argued that the notion of ‘fractals’ can augment current understanding of sociospatialities in three ways. First, it can pose questions about the scalar position of the observer or the grain of observation; second, as a signifier of particular attributes, it prompts observation and description of particular structuring processes; and third, the epistemic access afforded by the concept can open up possibilities for transformative interventions and thereby inform the same. The theoretical usefulness of the concept is demonstrated by discussing the territory, place, scale, and networks (TPSN) model for theorising sociospatial relations advanced by B Jessop, N Brenner, and M Jones in their 2008 paper “Theorizing sociospatial relations”, published in this journal (volume 26, pages 389–401). It is suggested that a heuristic arising from a ‘fractal’ ontology can contribute to a polymorphous, as opposed to polyvalent, understanding of sociospatial relations.

The bile acid receptor TGR5 does not interact with β-arrestins or traffic to endosomes but transmits sustained signals from plasma membrane rafts.

TGR5 is a G protein-coupled receptor that mediates bile acid (BA) effects on energy balance, inflammation, digestion and sensation. The mechanisms and spatiotemporal control of TGR5 signaling are poorly understood. We investigated TGR5 signaling and trafficking in transfected HEK293 cells and colonocytes (NCM460) that endogenously express TGR5. BAs (deoxycholic acid, DCA, taurolithocholic acid, TLCA) and the selective agonists oleanolic acid (OA) and 3-(2-chlorophenyl)-N-(4-chlorophenyl)-N, 5-dimethylisoxazole-4-carboxamide (CCDC) stimulated cAMP formation but did not induce TGR5 endocytosis or recruitment of β-arrestins, assessed by confocal microscopy. DCA, TLCA and OA did not stimulate TGR5 association with β-arrestin 1/2 or G protein-coupled receptor kinase (GRK) 2/5/6, determined by bioluminescence resonance energy transfer. CCDC stimulated a low level of TGR5 interaction with β-arrestin2 and GRK2. DCA induced cAMP formation at the plasma membrane and cytosol, determined using exchange factor directly regulated by cAMP (Epac2)-based reporters, but cAMP signals did not desensitize. AG1478, an inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase, the metalloprotease inhibitor batimastat, and methyl-β-cyclodextrin and filipin, which block lipid raft formation, prevented DCA stimulation of extracellular signal regulated kinase (ERK1/2). BRET analysis revealed TGR5 and EGFR interactions that were blocked by disruption of lipid rafts. DCA stimulated TGR5 redistribution to plasma membrane microdomains, localized by immunogold electron microscopy. Thus, TGR5 does not interact with β-arrestins, desensitize or traffic to endosomes. TGR5 signals from plasma membrane rafts that facilitate EGFR interaction and transactivation. An understanding of the spatiotemporal control of TGR5 signaling provides insights into the actions of BAs and therapeutic TGR5 agonists/antagonists.

Shared parenting, law and policy: considering power within the framework of autopoietic theory

This paper uses the last few decades’ developments in the area of shared parenting to explore power within the framework of autopoietic theory. It traces how, prompted by turbulence from the political subsystem, family law has made several unsuccessful attempts to solve the perceived problem of post-separation dual-household parenting. It agrees with Luhmann and Teubner that closed autopoietic systems’ developments are limited by their normative and cognitive frameworks, and also argues that changes, which have occurred in family law, show that closed social systems do not function in total isolation. It considers power as ego’s ability to limit alter’s choices. In our functionally differentiated society, with its recent proliferation of communication, power appears more diffuse and impossible to plot into causal one-way relationships.

Understanding ENSO diversity

El Niño–Southern Oscillation (ENSO) is a naturally occurring mode of tropical Pacific variability, with global impacts on society and natural ecosystems. While it has long been known that El Niño events display a diverse range of amplitudes, triggers, spatial patterns, and life cycles, the realization that ENSO’s impacts can be highly sensitive to this event-to-event diversity is driving a renewed interest in the subject. This paper surveys our current state of knowledge of ENSO diversity, identifies key gaps in understanding, and outlines some promising future research directions.

Märkskyltprogram för mättransformatorer

Detta examensarbete utfördes på ABB Power Technologies i Ludvika med syfte att förenkla tillverkningen av märkskyltar till mättransformatorer.Tidigare utformades alla skyltar för hand i Excel utifrån data från ett beräkningsprogram. Det gjorde att det behövdes en mall för varje variant i varje språk vilket ledde till väldigt många mallar. På ABB ville man både komma ifrån mängden olika mallar och det tidskrävande handarbetet som dessutom kunde resultera i att skyltarna inte fick enhetligt utseende. Genom att göra ett program som automatiskt genererar skyltarna utifrån en standardmall med hjälp av en fil från beräkningsprogrammet sparas mycket tid och arbete. Den som utformar skylten behöver då bara lägga till några få data själv och kan välja språk direkt i programmet istället för att behöva skriva allt för hand.Resultatet av detta examensarbete blev ett program som används av ABB för att göra skyltar till nästan alla mättransformatorer.

Elitidrottsproblem? : En kvalitativ studie om elitidrottares karriäravslutning

This paper used a qualitative technique from a social scientific perspective, a model based on Hewitt and his theory of the self-concept. The purpose of this study was to investigate why some elite athletes experience troublesome periods after their career ending. Interviews were performed with five elite athletes with varying experiences after career ending. The length of the elite athlete careers vary between 7 to 17 years. Two groups were made based upon experiences after career ending. Group 1 had experienced problems, for example suicide tendency, and group 2 had not. The result shows that a troublesome period can come up independently of career ending. The self-concept was investigated during the career and further different kind of variables which could affect the self as training and competition, social relations both before and after termination from sport. Result indicates that an individual in group 2 who has a high complexity in the self-concept based upon significant others outside the elite sport during the career copes with the new situation after career ending much better than group 1 who have not. To build up the self based only upon significant others in the elite sport seems to give expression in a strengthen self. Intensity in training and competition did not have a connection with a troublesome period after retirement from sport but it could prevent establishing contact with others outside the elite sport and reduce a high complexity in the self-concept. The result further shows that elite athletes who practise an individual sport trains in to a greater extent than elite athletes in a seasonal sport. Result also shows that practising a sport with one day off a week, contributes to better opportunities for developing a higher complexity in the self-concept. Suspicions has also rouse that practising an elite sport on the highest level can lead to extensive focusing that further leads to social isolation from individuals outside elite sport. To build up the self upon significant others outside elite sport during the career and keep in touch with significant others from elite sport after the career seems to be the key to avoid problems after the career ending. Suggestions about further investigations are made to see if medial exposure and status can affect the self.

Utvärdering av mätmetoder för att fastställa lackmängden vid offsettryckning on-line

This project has been made in cooperation with Stora Enso Research Centre Falun (Research). Thebackground of the project is that Research has customers who demand a method to measure the quantityof varnish online in offset printing. The aim with the project is to investigate if any test method correlateswith the quantity of varnish and to improve the understanding of the variables in the varnishingunit. The goal with the project is to develop a functional method. Two printing trials have beenperformed. The aim with the first trial was to investigate how different factors in the printer influencedthe quantity of varnish using reduced factoranalysis. The aim of the second trial was to analyse onlya reduced numbers of factors in the varnishing unit. The methods that were used to measure the varnishingquantity are weighing, IR-analysis, gloss, whiteness and brightness. Results from the projectshow that the weighing method does not work in this study due to basis weight variations of the sheets.The results from weighing did not agree with the results from the other methods. On the other handthere is a strong correation between the IR- and the glossmethods.

Varmsmidning av aluminiumlegering 6026 T9 : Warm forging of aluminum alloy 6026 T9

In this project forging of aluminum alloy Al 6026 T9 has been performed in the temperature range of 400 °C – 470 °C. The alloy which was in the shape of a cylindrical billet was formed in a press with the aim of analyzing the effect of different forging temperatures and required press load for optimal die filling. The component’s dimensions were later measured and compared to a reference piece. To ease the flow of material a lubricant was used between the billet and the die. This was demonstrated by compressing the billet with and without any lubricant.The performed experiments show that the lubricant reduces friction and makes it easier for the material to flow into the die. Higher billet temperature than 450 °C is deemed unnecessary as it does not give any significant improvement in filling the die. The experiments also conclude that a press load of at least 280 tons is required for these conditions.

Hela och halva samtal : Olika samtalsformers inverkan på arbetsprestationen

Denna studie grundar sig på en undersökning av hur 58 gymnasieelevers arbetsförmåga påverkades av exponering för dels ett traditionellt samtal mellan två personer och dels ett mobiltelefonsamtal. Utifrån teorier om den proaktiva hjärnan och det resursmässigt begränsade korttidsminnet utformades studiens huvudsakliga hypoteser; att mobilsamtal stör mer än vanliga samtal samt att denna distraktion blir mer påtaglig då försökspersonen utför uppgifter av mer komplex karaktär. Resultaten visade sig ge stöd åt hypotesen att mobiltelefonsamtal distraherar personer i högre utsträckning än vad traditionella samtal gör. Studien kunde dock inte påvisa att denna distraktion blir mer tydlig då personer utför mer komplexa uppgifter även om resultatet hade en tendens att gå i den riktningen. Författaren menar att studier likt denna ger ett viktigt vetenskapligt inlägg till debatten om hur öppna kontorslandskap (där de anställda ständigt exponeras för kollegors samtal) påverkar människors arbetsprestationer.

Sociala faktorers inverkan på elevers intentioner till högre studier : En applikation av Theory of planned behavior

Denna studie grundar sig på en enkätundersökning av 59 gymnasieungdomars intentioner till att inom de närmaste 5 åren påbörja studier vid högskola eller universitet. Undersökningen är baserad på Theory of planned behavior och syftar till att testa teorins pålitlighet i att besvara vilken av de socialt betingade bakgrundsfaktorerna attityd, subjektiv norm och upplevd beteendekontroll som utgör den bästa prediktorn för undersökningsdeltagarnas intentioner. Därtill undersöks dessa faktorers samband med föräldrarnas utbildningsnivå. Theory of planned behavior visade sig vara ett reliabelt mätinstrument gällande studiens övriga frågor, där den upplevda beteendekontrollen och den subjektiva normen utgjorde signifikanta prediktorer gällande undersökningsdeltagarnas intentioner. Därtill påvisades samband mellan föräldrars utbildningsnivå och deltagarnas intentioner samt subjektiva norm. Författaren menar att studier likt denna ger ett värdefullt bidrag till det viktiga arbetet med att förverkliga den svenska skolans likvärdighetsmål.

Defining Relevant Product Markets for Pharmaceuticals

To identify the relevant product markets for Swedish pharmaceuticals, a spatial econometrics approach is employed. First, we calculate Moran’s Is for different market definitions and then we use a spatial Durbin model to determine the effect of price changes on quantity sold off own and competing products. As expected, the results show that competition is strongest between close substitutes; however, the relevant product markets for Swedish pharmaceuticals extend beyond close substitutes down to products included in the same class on the four-digit level of the Anatomic Therapeutic Chemical system as defined by the World Health Organization. The spatial regression model further indicates that increases in the price of a product significantly lower the quantity sold of that product and in the same time increase the quantity sold of competing products. For close substitutes (products belonging to the same class on the seven-digit level of the Anatomic Therapeutic Chemical system), as well as for products that, without being close substitutes, belong to the same therapeutic/pharmacological/chemical subgroup (the same class on the five-digit level of the Anatomic Therapeutic Chemical system), a significant change towards increased competition is also visible after 1 July 2009 when the latest policy changes with regards to pharmaceuticals have been implemented in Sweden.

Employment Protection Legislation and Firm Growth : Evidence from a Natural Experiment

A natural experiment is used to identify the causal relationship between employment protection legislation and fi…rm growth. The natural experiment occurred in Sweden in 2001, when an exemption made it possible for fi…rms with less than eleven employees to exclude two workers from the last-in-fi…rst-out principle when dismissing personnel. The estimated average treatment effect of the reform show that the number of employees increased with 0.135 percent in fi…rms with 5-9 employees relative to fi…rms with 10-15 employees, which corresponds to over 5,000 additional jobs per year created by the reform. Firms with ten employees, just below the size threshold, became 3.4 percent less likely to increase their workforce to a level surpassing the threshold, indicating that the last-in-…first-out rule prevented these …firms from growing. Thus, employment protection legislation seems to act as a growth barrier for small fi…rms.