MHC promoter polymorphism in grey wolves and domestic dogs

A functional immune system requires a tight control over major histocompatibility complex (MHC) gene transcription, as the abnormal MHC expression patterns of severe immunodeficiency and autoimmune diseases demonstrate. Although the regulation of MHC expression has been well documented in humans and mice, little is known in other species. In this study, we detail the level of polymorphism in wolf and dog MHC gene promoters. The promoter regions of the DRB, DQA and DQB locus were sequenced in 90 wolves and 90 dogs. The level of polymorphism was high in the DQB promoters, with variation found within functionally relevant regions, including binding sites for transcription factors. Clear associations between DQB promoters and exon 2 alleles were noted in wolves, indicating strong linkage disequilibrium in this region. Low levels of polymorphism were found within the DRB and DQA promoter regions. However, a variable site was identified within the T box, a TNF-alpha response element, of the DQA promoter. Furthermore, we identified a previously unrecognised 18-base-pair deletion within exon 1 of the DQB locus.

Annotated record of the detailed examination of Mn deposits from R/V Atlantis Cruise 157 stations

The cores described are taken during the R/V Atlantis Cruise 157 from August until September 1949 by the Woods Hole Oceanographic Institution. A total of 19 cores were recovered and are available at Woods Hole Oceanographic Institution for sampling and study.

Annotated record of the detailed examination of Mn deposits from R/V Caryn Cruise 10 stations

The cores described are taken during the R/V Caryn Cruise 10 in July 1949 by the Woods Hole Oceanographic Institution. A total of 14 cores were recovered and are available at Woods Hole Oceanographic Institution for sampling and study.

Annotated record of the detailed examination of Mn deposits from R/V Atlantis Cruise 158 stations

The cores described are taken during the R/V Atlantis Cruise 158 from September until October 1949 by the Woods Hole Oceanographic Institution. A total of 5 cores were recovered and are available at Woods Hole Oceanographic Institution for sampling and study.

Annotated record of the detailed examination of Mn deposits from R/V Atlantis Cruise 260 stations

The cores described here were taken during the R/V Atlantis Cruise 260 from October until November 1960 by the Woods Hole Oceanographic Institution at the Muir Seamount. A total of 27 cores and dredges were recovered and are available at Woods Hole Oceanographic Institution for sampling and study.

Hans Blumenberg and Feminism

The German philosopher Hans Blumenberg [1920-1996] was interested in feminist issues during the last two decades of his life as shown their dedication and effort in compiling selected cuts in the media related to the topic of women and their development of multiple short essays inspired by the latter and countless curious anecdotes. Hans Blumenberg and feminism seeks to inform the reader about the existence of a blumenberguian thought line of research totally unexplored so far. It can only be revealed through the study of the philosopher ‘Nachlaβ’ found in the Deutsches literaturarchiv Marbach (Stuttgart) which I personally had a chance to dig through the award of a research grant from the DAAD (Deutscher Akademischer Dienst Austage).

Keisarillisen majesteetin armosta wahwistettu palo-asetus Wiipurin kaupungille, annettu Helsingissä 21 päiwänä tammikuuta wuonna 1840

Julkaistu myös ruotsiksi nimellä: Brandordning för Wiborgs stad. - Julkaistu myös venäjäksi nimellä: Požarnyj ustav dlâ g. Vyborga.

Hans kejserliga majestäts i nåder fastställde brandordning för Wiborgs stad, gifwen i Helsingfors den 21 Januarii 1840

Julkaistu myös suomeksi nimellä: Palo-asetus Wiipurin kaupungille. - Julkaistu myös venäjäksi nimellä: Požarnyj ustav dlâ g. Vyborga.

Projekt badawczy w projekcie edukacyjnym

W zależności od ujęcia projekt jest metodą lub strategią nauczania (Nowacki i wsp, 1999). W niektórych źródłach zaliczany do grupy metod nauczania przez dociekanie (ang. inquiry based learning) (Bransford i in., 2000). Metody nauczania oparte na dociekaniu zyskują coraz bardziej na popularności, także w dydaktyce akademickiej. W niniejszej pracy przedstawiono analizę jakościową 25 projektów zajęć dydaktycznych opracowanych przez doktorantów Wydziału Biologii UAM, w których projekt badawczy był składnikiem projektu edukacyjnego, a całość była propozycją zajęć dla studentów tegoż wydziału.

Polski Współczynnik Wpływu a kultury cytowań w humanistyce

The article discusses the formula for a new Polish bibliometric indicator, i.e., the Polish Impact Factor (Polski Współczynnik Wpływu) from the point of view of the humanities. Our study examines two prestigious Polish humanities journals (Pamiętnik Literacki and Diametros – An Online Journal of Philosophy) to evaluate the underlying assumptions of the Polish Impact Factor. We have analyzed all articles published from 2004 to 2014 (N = 850, N = 555, respectively) and all references included in these articles (N = 21,805, N = 8,298, respectively). When interpreting the findings, we have assumed that different groups of sciences are characterized by different citation cultures. Our findings show that the formula for the Polish Impact Factor does not take into account the most cited sources in the humanities, i.e., books and chapters. Moreover, many citations will not be included in the formula because of the citation age: the formula for the Polish Impact Factor is provided for the citations whose age is not higher than 5 years. We have analyzed the citation age of all citations and used Price’s Index to interpret the result. We have found out that most of citations are older than 5 years (84,2 percent and 73,2 percent, respectively). Our analysis shows that the Polish Impact Factor is not an adequate tool for a bibliometric evaluation of the journals in the humanities in Poland. The article concludes with a discussion of how the Polish Impact Factor could be improved.

Budowa, asymetria i dymorfizm płciowy stawu ramiennego w populacji średniowiecznej i współczesnej

Wydział Biologii: Instytut Antropologii

Mechanizmy wybiórczości środowiskowej u świstunki leśnej Phylloscopus sibilatrix

Wydział Biologii

Wokół składni „Rozmyślań dominikańskich”

Wydział Filologii Polskiej i Klasycznej

Słownik języka miyako Nikołaja Newskiego: rekonstrukcja oraz analiza etnolingwistyczna rękopisu

Wydział Neofilologii: Katedra Orientalistyki

Rola białka Hfq w oddziaływaniu niekodujących RNA bakterii z sekwencją kodującą mRNA

Wydział Biologii: Instytut Biologii Molekularnej i Biotechnologii