933 resultados para Arms of dominion


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Differential Phase Shift Keying (DPSK) modulation format has been shown as a robust solution for next-generation optical transmission systems. One key device enabling such systems is the delay interferometer, converting the signal phase information into intensity modulation to be detected by the photodiodes. Usually, Mach-Zehnder interferometer (MZI) is used for demodulating DPSK signals. In this paper, we developed an MZI which is based on all-fiber Multimode Interference (MI) structure: a multimode fiber (MMF) located between two single-mode fibers (SMF) without any transition zones. The standard MZI is not very stable since the two beams go through two different paths before they recombine. In our design the two arms of the MZI are in the same fiber, which will make it less temperature-sensitive than the standard MZI. Performance of such MZI will be analyzed from transmission spectrum. Finally such all-fiber MI-based MZI (MI-MZI) is used to demodulate 10 Gbps DPSK signals. The demodulated signals are analyzed from eye diagram and bit error rate (BER).

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The function of the small-Mr Ras-like GTPase Rap1 remains largely unknown, but this protein has been demonstrated to regulate cortical actin-based morphologic changes in Dictyostelium and the oxidative burst in mammalian neutrophils. To test whether Rap1 regulates phagocytosis, we biochemically analyzed cell lines that conditionally and modestly overexpressed wild-type [Rap1 WT(+)], constitutively active [Rap1 G12T(+)], and dominant negative [Rap1 S17N(+)] forms of D. discoideum Rap1. The rates of phagocytosis of bacteria and latex beads were significantly higher in Rap1 WT(+) and Rap1 G12T(+) cells and were reduced in Rap1 S17N(+) cells. The addition of inhibitors of protein kinase A, protein kinase G, protein tyrosine kinase, or phosphatidylinositide 3-kinase did not affect phagocytosis rates in wild-type cells. In contrast, the addition of U73122 (a phospholipase C inhibitor), calphostin C (a protein kinase C inhibitor), and BAPTA-AM (an intracellular Ca2+ chelator) reduced phagocytosis rates by 90, 50, and 65%, respectively, suggesting both arms of the phospholipase C signaling pathways played a role in this process. Other protein kinase C–specific inhibitors, such as chelerythrine and bisindolylmaleimide I, did not reduce phagocytosis rates in control cells, suggesting calphostin C was affecting phagocytosis by interfering with a protein containing a diacylglycerol-binding domain. The addition of calphostin C did not reduce phagocytosis rates in Rap1 G12T(+) cells, suggesting that the putative diacylglycerol-binding protein acted upstream in a signaling pathway with Rap1. Surprisingly, macropinocytosis was significantly reduced in Rap1 WT(+) and Rap1 G12T(+) cells compared with control cells. Together our results suggest that Rap1 and Ca2+ may act together to coordinate important early events regulating phagocytosis.

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Also issued as part of collection with collective title page, engraved portrait of author, biographical preface, and contents list: "R.P. Francisci Suarez Granatensis, e Societate Iesu Doctoris Theologi, et in Regia Conimbricensi Academia primarij theologiae professoris emeriti Opera omnia quorum cathalogum vide lector in vita authoris. Moguntiae, Sumptibus Hermanni Mylij Birckmanni Excudebat Balthasar Lippius. Anno M. DCXXI."

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"Ce journal ... dont [Pierre] Rousseau rédigea les 28 premières livraisons parut depuis le 1er janvier 1756, jusqu'au 9 novembre 1793, époque à laquelle il se fondit dans l'Esprit des journaux. Rousseau eut pour collaborateurs un grand nombre d'écrivains, parmi les quels nous nommerons: J. d'Alembert, A. J. D. Bassinet, A. Bret ... J. L. Castilhon ... S. R. N. Chamfort ... etc." - Le Bibliophile belge, 3. année, p. 112.

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Includes index.

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Engraved throughout. Architectural title leaf includes the arms of Cardinal Alessandro Farnese, to whom the work is dedicated, and the half-length port. of Vignola facing to the viewer's right. Plates are printed on one side of the leaf only, and are arranged in pairs on a verso and the facing recto. The 5 leaves at the end are from the series of 7 "Porte di Michel Angelo." Over 3 of the doorways are inscriptions relating to the Farnese.

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The engravings of the paintings are from many engravers: I. Troyen, N. v. Hoij, L. Vosterman, P. Lisebetius, L. Popels, etc.