Recherches sur l'organisation, la fructification et la classification de plusieurs genres d'algues : avec la description de quelques espèces inédites on peu connues : essai d'une répartition des polypiers calcifères de Lamouroux dans la classe des algues /

Spine title: Thése pour le doctorate.

Coordonnées parallèles et axiales. Méthode de transformation géométrique et procédé nouveau de calcul graphique déduits de la considération des coordonnées parallèlles,

Available on demand as hard copy or computer file from Cornell University Library.

Physiologie médicale de la circulation du sang : basée sur l'étude graphique des mouvements du coeur et du pouls artériel : avec application aux maladies de l'appareil circulatoire /

Mode of access: Internet.

Recherches sur les facteurs de la répartition et sur le role des mycorhizes,

At head of title: Faculté des Sciences de l'Université de Paris.

Le dessin linéaire, enseigné aux ouvriers, ou Les vraies leçons de la science graphique applicables à tous les arts.

Mode of access: Internet.

Cinq symphonies pour petit orchestre. Partition. 3. Sérénade (1921).

For flute, clarinet, bassoon, violin, viola, violoncello and double bass.

Traite de statique graphique

Mode of access: Internet.

Contenancy and partition

Mode of access: Internet.

Diffusion modeling of percutaneous absorption kinetics: 3. Variable diffusion and partition coefficients, consequences for stratum corneum depth profiles and desorption kinetics

Stratum corneum (SC) desorption experiments have yielded higher calculated steady-state fluxes than those obtained by epidermal penetration studies. A possible explanation of this result is a variable diffusion or partition coefficient across the SC. We therefore developed the diffusion model for percutaneous penetration and desorption to study the effects of either a variable diffusion coefficient or variable partition coefficient in the SC over the diffusion path length. Steady-state flux, lag time, and mean desorption time were obtained from Laplace domain solutions. Numerical inversion of the Laplace domain solutions was used for simulations of solute concentration-distance and amount penetrated (desorbed)-time profiles. Diffusion and partition coefficients heterogeneity were examined using six different models. The effect of heterogeneity on predicted flux from desorption studies was compared with that obtained in permeation studies. Partition coefficient heterogeneity had a more profound effect on predicted fluxes than diffusion coefficient heterogeneity. Concentration-distance profiles show even larger dependence on heterogeneity, which is consistent with experimental tape-stripping data reported for clobetasol propionate and other solutes. The clobetasol propionate tape-stripping data were most consistent with the partition coefficient decreasing exponentially for half the SC and then becoming a constant for the remaining SC. (C) 2004 Wiley-Liss, Inc.

Empirical prediction of peptide octanol-water partition coefficients

Peptides are of great therapeutic potential as vaccines and drugs. Knowledge of physicochemical descriptors, including the partition coefficient P (commonly expressed in logarithm form: logP), is useful for screening out unsuitable molecules and also for the development of predictive Quantitative Structure-Activity Relationships (QSARs). In this paper we develop a new approach to the prediction of LogP values for peptides based on an empirical relationship between global molecular properties and measured physical properties. Our method was successful in terms of peptide prediction (total r2 = 0.641). The final model consisted of 5 physicochemical descriptors (molecular weight, number of single bonds, 2D-VDW volume, 2D-VSA hydrophobic and 2D-VSA polar). The approach is peptide specific and its predictive accuracy was high. Overall, 67% of the peptides were able to be predicted within +/-0.5 log units from the experimental values. Our method thus represents a novel prediction method with proven predictive ability.

A Partition Metric for Clustering Features Analysis

A new distance function to compare arbitrary partitions is proposed. Clustering of image collections and image segmentation give objects to be matched. Offered metric intends for combination of visual features and metadata analysis to solve a semantic gap between low-level visual features and high-level human concept.