989 resultados para 13TH INTERNATIONAL-CONGRESS


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1st ASPIC International Congress

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1st ASPIC International Congress

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1st ASPIC International Congress

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13th International Conference on Autonomous Robot Systems (Robotica), 2013, Lisboa

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13th International Conference on Autonomous Robot Systems (Robotica), 2013

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13th International Conference on Autonomous Robot Systems (Robotica), 2013

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Proceedings of the 13th International UFZ-Deltares Conference on Sustainable Use and Management of Soil, Sediment and Water Resources - 9–12 June 2015 • Copenhagen, Denmark

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Poster (and extended abstract) presented at the 13th International Conference "Libraries in the Digital Age (LIDA 2014)" held on 16-20th June, University of Zadar, Zadar, Croatia

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Ochratoxin A (OTA) is a very well known mycotoxin found in several food commodities for which maximum limits are being discussed in EC in other to produce appropriate regulations. OTA is one of several ochratoxins produced by Aspergillus and Penicillium species. All the compounds in this group have a molecular structure very similar to OTA and some were already isolated from natural substrates. Several of these compounds such as ochratoxin , methyl and ethyl ester of ochratoxin A, 4-R and S-hydroxyochratoxin A, 10-hydroxyochratoxin A and ochratoxin A open lactone are commercially unavailable. However, they can be easily synthesized through OTA modification. With the main objective of its application on further research works, OTA production, isolation and purification has been optimised from an A. alliaceus strain grown on wheat medium. Synthesis and purification of some OTA derivatives has been achieved and an HPLC method for their detection was optimised. Data about their production by several species of Aspergillus will be presented. The toxicological properties of ochratoxins are still not very clear and a future EC safety limit for OTA will depend on e.g., a better clarification of its carcinogenity. Could OTA derivatives play a role here?