Langdon "Bif Lea" UM football coach, 1900, as Princeton player

[picture of Leas as Princeton player from Mayo plug cut tobacco trading, ca. 1896, from card reprinted in 1990]

Projected water-level declines in the Ogallala aquifer in Lea County, New Mexico /

Bibliography: p. 82-84.

Muuttuva lapsen maailma. Minttu-kuvakirjat viidellä vuosikymmenellä 1978–2015.

Tutkimuksen tavoitteena on selvittää, miten kuvaa lapsuudesta rakennetaan verbaalisilla ja visuaalisilla elementeillä kuvakirjan tarjoamien mahdollisuuksien ja rajoitusten puitteissa. Tutkimuskohteinani toimivat Maikki Harjanteen Minttu-kuvakirjoista löytämäni kirjaparit. Samasta aiheesta kirjoitettuja kirjapareja ovat joulusta kertovat kirjat mintun joulu (1979) ja Mintun joulukirja (1989), lemmikin liittymistä Mintun perheeseen käsittelevät kirjat minttu saa koiran (1982) ja Minttu saa oman koiran (2007), mummon nimikkoteokset minttu mummolassa (1978) ja Minttu ja mummo (2010) sekä syntymäpäivistä kertovat kirjat mintun kiva päivä (1979) ja Mintun syntymäpäivät (2014). Tutkin siis, miten kuvaa lemmikeistä, koirista, mummoista, jouluista ja syntymäpäivistä rakennetaan näissä kuvakirjapareissa. Tutkin tutkimuskohteitani ikonoteksteinä eli teoksina, jotka muodostuvat sanan ja kuvan vuorovaikutuksessa. Kuvan ja sanan suhteessa tapahtuneen muutoksen määrittelyn apuna käytän Ulla Rhedinin kolmea kuvakirjakategoriaa sekä Maria Nikolajevan ja Carole Scottin kertovuuden aspektin varaan perustuvaa kuvakirjajaottelua. Representaation ymmärrän Mikko Lehtosen ja Stuart Hallin tapaan kaksisuuntaiseksi ilmiöksi, toisinnoksi, jolla on kuitenkin maailmaa muokkaava voima. Mintut ovat muuttuneet 70-luvun ensimmäisistä kuvakirjoista 2010-luvulle paljon niin visuaalisesti kuin verbaalisesti, mikä on vaikuttanut kirjojen tuottamaan lemmikki-, mummo-, joulu- ja syntymäpäiväkuvaan. Alkutuotannossa painottui kerronnan visuaalinen puoli ja lopputuotannossa tekstin osuus kerronnassa on kasvanut suureksi. Alkutuotannon Mintut pyrkivät mimeettiseen ja realistiseen kuvaukseen kun taas lopputuotanto saa karnevalismin ja nonsensen piirteitä. Samalla Minttujen arvot ovat säilyneet jokseenkin samoina: Vaikka Minttu-kirjoissa representoidaankin melko idyllisesti boheemia lapsiperheen arkea, löytyy niistä säröjä, joilla Mintut kyseenalaistavat valtakulttuuria. Mintut puhuvat vihreiden arvojen puolesta kulutuskulttuuria vastaan ja tekevät selväksi, ettei lapsi tarvitse leluja ja kalliita harrastuksia, vaan oman tärkeän aikuisen aikaa. Minttu-kuvakirjat tuottavat tietynlaista kuvaa lapsuudesta eri vuosikymmenillä. Kuvakirjat luovat omaa todellisuuttaan representoidessaan asioita, eikä niitä voida pitää vallan käytön suhteen neutraalina mediana. Niillä on agenda muuttaa maailmaa.

La multiculturalidad en la educación musical obligatoria de la Comunidad Autónoma Vasca: una aproximación a la situación actual y un estudio de caso: el alumnado inmigrante marroquí en las comarcas de Lea-Artibai y Bajo Deva

689 p.

Uso do bivalve límnico Anodontites tenebricosus (LEA, 1834) no biomonitoramento de metais do Rio Ribeira de Iguape

This study investigated the contamination of the Ribeira de Iguape River - RIR by Cd, Zn, Cr and Pb, using the bivalve Anodontites tenebricosus as a biomonitor. Metal concentrations in tissue samples were measured by HR-ICPMS. Bivalve tissues exhibited mean levels of 1.00 µg/g Cd; 152.89 µg/g Zn; 14.79 µg/g Cr and 4.40 µg/g Pb. Lead concentrations were comparable to those reported for moderately contaminated sites. The results showed that Pb is bioavailable to the bivalves, exhibiting high concentrations and exceeding both natural and reference values for human consumption. The freshwater bivalve Anodontites tenebricosus is a suitable biomonitor of contamination by metals.

Oak Lea Wildlife Management Area

The South Carolina Department of Natural Resources provides area maps of regions of the state that identify agency-owned and managed Wildlife Management Areas. This is a map of the Oak Lea Wildlife Management Area.

Diagnosis, Treatment, And Follow-up Of Medullary Thyroid Carcinoma: Recommendations By The Thyroid Department Of The Brazilian Society Of Endocrinology And Metabolism.

Medullary thyroid carcinoma (MTC) originates in the thyroid parafollicular cells and represents 3-4% of the malignant neoplasms that affect this gland. Approximately 25% of these cases are hereditary due to activating mutations in the REarranged during Transfection (RET) proto-oncogene. The course of MTC is indolent, and survival rates depend on the tumor stage at diagnosis. The present article describes clinical evidence-based guidelines for the diagnosis, treatment, and follow-up of MTC. The aim of the consensus described herein, which was elaborated by Brazilian experts and sponsored by the Thyroid Department of the Brazilian Society of Endocrinology and Metabolism, was to discuss the diagnosis, treatment, and follow-up of individuals with MTC in accordance with the latest evidence reported in the literature. After clinical questions were elaborated, the available literature was initially surveyed for evidence in the MedLine-PubMed database, followed by the Embase and Scientific Electronic Library Online/Latin American and Caribbean Health Science Literature (SciELO/Lilacs) databases. The strength of evidence was assessed according to the Oxford classification of evidence levels, which is based on study design, and the best evidence available for each question was selected. Eleven questions corresponded to MTC diagnosis, 8 corresponded to its surgical treatment, and 13 corresponded to follow-up, for a total of 32 recommendations. The present article discusses the clinical and molecular diagnosis, initial surgical treatment, and postoperative management of MTC, as well as the therapeutic options for metastatic disease. MTC should be suspected in individuals who present with thyroid nodules and family histories of MTC, associations with pheochromocytoma and hyperparathyroidism, and/or typical phenotypic characteristics such as ganglioneuromatosis and Marfanoid habitus. Fine-needle nodule aspiration, serum calcitonin measurements, and anatomical-pathological examinations are useful for diagnostic confirmation. Surgery represents the only curative therapeutic strategy. The therapeutic options for metastatic disease remain limited and are restricted to disease control. Judicious postoperative assessments that focus on the identification of residual or recurrent disease are of paramount importance when defining the follow-up and later therapeutic management strategies.

[between The Country And The Laboratory: The Dynamics Of The Production Of Knowledge At The Menopause Outpatients Clinic At Caism, Unicamp.]

This study investigates the practices involved in the production of knowledge about menopause at Caism, Unicamp, a reference center for public policies for women's health. Gynecological appointments and psychological support meetings were observed, and women and doctors were interviewed in order to identify what discourse circulates there and how different actors are brought in to ensure that the knowledge produced attains credibility and travels beyond the boundaries of the teaching hospital to become universal. The analysis is based on localized studies aligned with social studies of science and technology.

[between The Country And The Laboratory: The Dynamics Of The Production Of Knowledge At The Menopause Outpatients Clinic At Caism, Unicamp].

This study investigates the practices involved in the production of knowledge about menopause at Caism, Unicamp, a reference center for public policies for women's health. Gynecological appointments and psychological support meetings were observed, and women and doctors were interviewed in order to identify what discourse circulates there and how different actors are brought in to ensure that the knowledge produced attains credibility and travels beyond the boundaries of the teaching hospital to become universal. The analysis is based on localized studies aligned with social studies of science and technology.

Consensos em tireoide: guias para a prática clínica

161

Consenso brasileiro para a abordagem clínica e tratamento do hipotireoidismo subclínico em adultos: recomendações do Departamento de Tireoide da Sociedade Brasileira de Endocrinologia e Metabologia

INTRODUCTION: Subclinical hypothyroidism (SCH), defined as elevated concentrations of thyroid stimulating hormone (TSH) despite normal levels of thyroid hormones, is highly prevalent in Brazil, especially among women and the elderly. Although an increasing number of studies have related SCH to an increased risk of coronary artery disease and mortality, there have been no randomized clinical trials verifying the benefit of levothyroxine treatment in reducing these risks, and the treatment remains controversial. OBJECTIVE: This consensus, sponsored by the Thyroid Department of the Brazilian Society of Endocrinology and Metabolism and developed by Brazilian experts with extensive clinical experience with thyroid diseases, presents these recommendations based on evidence for the clinical management of SCH patients in Brazil. MATERIALS AND METHODS: After structuring the clinical questions, the search for evidence in the literature was initially performed in the MedLine-PubMed database and later in the Embase and SciELO - Lilacs databases. The strength of evidence was evaluated according to the Oxford classification system and established based on the experimental design used, considering the best available evidence for each question and the Brazilian experience. RESULTS: The topics covered included SCH definition and diagnosis, natural history, clinical significance, treatment and pregnancy, and the consensus issued 29 recommendations for the clinical management of adult patients with SCH. CONCLUSION: Treatment with levothyroxine was recommended for all patients with persistent SCH with serum TSH values > 10 mU/L and for certain patient subgroups.

Subcutaneous connective tissue response to primary root canal filling materials

This study evaluated the response of the subcutaneous connective tissue of BALB/c mice to root filling materials indicated for primary teeth: zinc oxide/eugenol cement (ZOE), Calen paste thickened with zinc oxide (Calen/ZO) and Sealapex sealer. The mice (n=102) received polyethylene tube implants with the materials, thereby forming 11 groups, as follows: I, II, III: Calen/ZO for 7, 21 and 63 days, respectively; IV, V, VI: Sealapex for 7, 21 and 63 days, respectively; VII, VIII, IX: ZOE for 7, 21 and 63 days, respectively; X and XI: empty tube for 7 and 21 days, respectively. The biopsied tissues were submitted to histological analysis (descriptive analysis and semi-quantitative analysis using a scoring system for collagen fiber formation, tissue thickness and inflammatory infiltrate). A quantitative analysis was performed by measuring the area and thickness of the granulomatous reactionary tissue (GRT). Data were analyzed by Kruskal-Wallis, ANOVA and Tukey's post-hoc tests (?=0.05). There was no significant difference (p>0.05) among the materials with respect to collagen fiber formation or GRT thickness. However, Calen/ZO produced the least severe inflammatory infiltrate (p<0.05). The area of the GRT was significantly smaller (p<0.05) for Calen/ZO and Sealapex. In conclusion, Calen/ZO presented the best tissue reaction, followed by Sealapex and ZOE.

Periapical repair after root canal filling with different root canal sealers

The aim of this study was to evaluate periapical repair after root canal filling with different endodontic sealers. Sixty-four root canals from dog´s teeth were filled, divided into 4 groups (n=16). Root canals were instrumented with K-type files and irrigated with 1% sodium hypochlorite solution. Root canals were filled in the same session by active lateral condensation of the cones and sealers: Intrafill, AH Plus, Roeko Seal and Resilon/Epiphany System. After 90 days, the animals were euthanized and the tissues to be evaluated were processed and stained with hematoxylin and eosin. For histopathological analysis, the following parameters were evaluated: inflammatory process, mineralized tissue resorption, and apical mineralized tissue deposition. Histopathological analysis demonstrated that Intrafill had less favorable results in terms of apical and periapical repair, compared to the other sealers (p<0.05). AH Plus, Roeko Seal, and Epiphany sealers had similar and satisfactory results (p>0.05). In conclusion, AH Plus and the materials Roeko Seal and Epiphany are good options for clinical use in Endodontics.