As respostas sociais para o estudante do ensino superior com paralisia cerebral

Dissertação apresentada à Escola Superior de Educação de Paula Frassinetti para obtenção do grau de mestre em intervenção comunitária, especialização em contextos de risco

Erziehung zur Gleichheit. Mathilde Franziska Annekes Töchter-Institut in Milwaukee und ihr Eintreten für Rechte der Frauen

Im Zentrum der vorliegenden Untersuchung steht das 1865 gegründete Töchter-Institut Mathilde Franziska Annekes in Milwaukee, Wisconsin. Dieses Schulprojekt der Achtundvierzigerin und Frauenrechtlerin wird verglichen mit Bildungsreformansätzen der Amerikanerin Catherine Beecher sowie solchen deutscher Pädagogen. Zum einen soll dabei die Besonderheit von Annekes Konzept herausgearbeitet werden, zum anderen soll der Stellenwert der Schule in den Frauenrechtsaktivitäten von Anneke beleuchtet werden. Die Analyse der sozialen Herkunft ihrer Schülerinnenschaft ergibt eine Neubewertung von Annekes Stellung als Frauenrechtlerin in Milwaukee. (DIPF/Orig.)

Actividad física y deportiva en los niños con discapacidad mental del Centro Educativo Calasanz de la Ciudad de Cuenca

En líneas generales este trabajo presenta como las personas con discapacidad son integras a la libre participación e involucramiento en diferentes actividades cotidianas de su vida. El impacto negativo de la discapacidad es una realidad social. Algunos grupos soportan niveles de exclusión y factores de discriminación, es decir, la situación de muchas de estas personas y sus familias se caracteriza por un rechazo severo, tales como la pobreza, la discriminación y la ausencia de igualdad efectiva de oportunidades. Es por ello que en el primer capítulo se va conocer las líneas generales, la importancia y la valoración del grado de desarrollo de sus capacidades y sobre todo sus necesidades educativas especiales En el capítulo dos, va encaminado a cómo mejorar las capacidades y habilidades de los alumnos con capacidades diferentes, es necesario mejorar o articular en las adaptaciones curriculares para un mayor manejo y aprendizaje apropiado con los estudiantes. En el capítulo tres, tiene que ver todo en cuanto a las planificaciones de trabajo, basados en las nuevas adaptaciones curriculares, guías, valoraciones, test, y resultados. El Capítulo IV, tiene que ver con las competencias en diferentes disciplinas deportivas; sus resultados, dentro de este proceso se ha implementado planes de clases adaptados a cada escolar; pero tomando en cuenta sus necesidades individuales, formados por el buen uso del tiempo libre en desarrollar actividades lúdicas con el fin de mejorar y potencializar en sus diferentes tipos de movimientos.

Das bildungstheoretische Potenzial inklusiver Pädagogik. Meilensteine der Konstruktion von Bildung und Behinderung am Beispiel von Kindern mit Lernschwierigkeiten

Inklusion erfordert Veränderungen, Umbau und Umdenken auf vielen Ebenen. Ob Teilhabe gelingt, entscheidet sich letztlich im pädagogischen Alltag. So muss in einem inklusiven Bildungssystem auch geklärt werden, was Bildung ausmacht, wenn sie alle Kinder adressiert. Was bedeutet hier Bildung und in welchem Zusammenhang stehen die Konstrukte von Bildung und Behinderung? Wurden doch traditionell die Grenzen des ersten systemwirksam mit der Zuschreibung des zweiten markiert. Das vorliegende Buch thematisiert in historischer Perspektive die sich verändernden Vorstellungen über Bildung, Behinderung(en) und Gerechtigkeit im Bildungssystem sowie die damit verbundenen kontroversen Debatten sowie die häufig uneinheitlichen, teils gegenläufigen Entwicklungen der sogenannten Sonder- und der sogenannten Regelpädagogik. Die Analyse arbeitet die Beiträge integrations- und inklusionspädagogischer Theorien (Reiser, Feuser, Prengel, Wocken, Reich) zu einem gemeinsamen Bildungsverständnis für alle Kinder heraus. Diese Potenziale integrations- und inklusionspädagogischer Theoriebildung werden eingeordnet in bildungstheoretische Dimensionen sowie in die aktuellen Debatten um Inklusion und Bildung als Menschenrecht. (DIPF/Orig.)

Offen werden für demokratiepolitische Themen. Politische Bewusstseinsbildung in verpflichtenden Gender-Trainings trotz persönlichen Widerstands

Wie kann in Seminaren zu Genderkompetenz Offenheit erzeugt werden, wenn die Teilnehmenden sich nicht freiwillig für den Besuch entschieden haben und daher mit Desinteresse oder Widerwillen reagieren? Der vorliegende Beitrag beschreibt ein didaktisches Vorgehen, das den persönlichen Widerstand von Teilnehmenden aufzulösen vermag und letztlich ein Problembewusstsein für soziale Ungleichheit initiiert. Zentral sind hierfür die Reflexion persönlicher Erfahrungen und ideologischer Diskussionen, die Ungleichheitsthemen meist mit sich bringen. Das vorgestellte didaktische Vorgehen im Gender Training, das u.a. Kompetenzerwartungen an Führungskräfte im Bildungsbereich entlang Geschlechterstereotypien aufdeckt, ist auch für andere Themen der politischen Bildung einsetzbar. Um also ein politisches Bewusstsein über Hierarchisierungs- und Diskriminierungsprozesse zu befördern, ist es wichtig, Ausschließungsprozesse im Alltag erlebbar zu machen und zu erkennen, wer vom Ausschluss anderer profitiert, wer die Ausschlusskriterien festlegt und dass unterschiedliche Kriterien dafür geeignet sind. (DIPF/Orig.)

Equity, equality and diversity : A cross-country comparison

Differences in the workplace, also known as workforce diversity, evoke varied approaches in different countries. These include equity, equal opportunities, affirmative action and managing diversity. This paper compares methods in the US, Canada, UK, India, and South Africa. The system in each country is described and compared using several parameters. These are: the emphasis on sameness or difference; focus on individuals versus groups, classes or categories; voluntary action versus compulsory requirements; and remedies available. All are examined within the context of the national background and culture. The paper concludes that each system has both benefits and drawbacks, and gives lie to the assumption that there is any perfect legislative or voluntary approach to workplace diversity.

Keeping the promise? Contextualizing inclusive education in developing countries

Inclusive education became a global promise corroborated by international declarations such as the Salamanca Statement (1994) and the Incheon Declaration (2015). Most countries worldwide have committed to the goal of inclusive education, putting a lot of pressure on so-called developing countries. Against this backdrop the threefold purpose of this book is to: 1. Generate research evidence on the development and implementation of inclusive education in developing countries, 2. Contextualize inclusive education in specific developing countries and contexts, and 3. Reflect on the future of inclusive education in developing countries. (DIPF/Orig.)

Effective Approaches to Enhancing the Social Dimension of Higher Education

Despite all intentions in the course of the Bologna Process and decades of investment into improving the social dimension, results in many national and international studies show that inequity remains stubbornly persistent, and that inequity based on socio-economic status, parental education, gender, country-of-origin, rural background and more continues to prevail in our Higher Education systems and at the labour market. While improvement has been shown, extrapolation of the gains of the last 40 years in the field show that it could take over 100 years for disadvantaged groups to catch up with their more advantaged peers, should the current rate of improvement be maintained. Many of the traditional approaches to improving equity have also necessitated large-scale public investments, in the form of direct support to underrepresented groups. In an age of austerity, many countries in Europe are finding it necessary to revisit and scale down these policies, so as to accommodate other priorities, such as balanced budgets or dealing with an aging population. An analysis of the current situation indicates that the time is ripe for disruptive innovations to mobilise the cause forward by leaps and bounds, instead of through incrementalist approaches. Despite the list of programmes in this analysis there is very little evidence as to the causal link between programmes, methodologies for their use and increases/improvements in equity in institutions. This creates a significant information gap for institutions and public authorities seeking for indicators to allocate limited resources to equity improving initiatives, without adequate evidence of effectiveness. The IDEAS project and this publication aims at addressing and improving this information gap. (DIPF/Orig.)

Leonie Herwartz-Emden / Verena Schurt / Wiebke Waburg: Mädchen und Jungen in Schule und Unterricht. Stuttgart: Kohlhammer Verlag 2012 (137 S.) [Rezension]

Rezension von: Leonie Herwartz-Emden / Verena Schurt / Wiebke Waburg: Mädchen und Jungen in Schule und Unterricht. Stuttgart: Kohlhammer Verlag 2012 (137 S.; ISBN 978-3-17-020903-9)

Klaus Hurrelmann / Tanjev Schultz (Hrsg.): Jungen als Bildungsverlierer. Brauchen wir eine Männerquote in Kitas und Schulen? Weinheim und Basel: Beltz Juventa 2012 (316 S.) [Rezension]

Rezension von: Klaus Hurrelmann / Tanjev Schultz (Hrsg.): Jungen als Bildungsverlierer. Brauchen wir eine Männerquote in Kitas und Schulen? Weinheim und Basel: Beltz Juventa 2012 (316 S.; ISBN 978-3-7799-2750-1)

Voices of nigerian women survivors of trafficking held in italian centres for identification and expulsion

Department of Equal Opportunities; Presidency of the Council of Ministries; Province of Rome (metropolitan area)

Câmara dos Deputados : democracia e igualdade de oportunidades entre mulheres e homens?

Esta pesquisa analisou as oportunidades das mulheres em termos de igualdade na ocupação de cargos de alta chefia na Câmara dos Deputados. A pesquisa de campo foi realizada entre novembro de 2005 e janeiro de 2006 e a amostra abrangeu 1.320 participantes. A Escala de Percepção de Igualdade de Oportunidades entre Mulheres e Homens foi aplicada para analisar a atitude dos servidores quanto a possibilidades e limites de ascensão da mulher na estrutura de cargos da organização. A escala constava de 34 itens, com respostas tipo Likert, e 6 itens sobre dados demográficos. A coleta de dados foi feita pela rede interna de computadores da Câmara dos Deputados, através de e-mail enviado aos 3.597 servidores do quadro efetivo. Os dados foram submetidos à análise dos componentes principais (ACP), rotação promax, com resultados meritórios (KMO = 86,0; Bartlett: 14894,879), para 4 fatores. Observaram-se diferenças entre mulheres e homens quanto aos escores obtidos. As oportunidades de ocupar cargo de alta chefia são menores para elas do que para eles. Há mais gerentes do sexo masculino, e os servidores, especialmente as mulheres que não ocupam posto de chefia, percebem que não há igualdade de oportunidades entre funcionários de ambos os sexos. ___________________________________________________________________________ ABSTRACT

Microfluidics-based single-cell functional proteomics microchip for portraying protein signal transduction networks within the framework of physicochemical principles, with applications in fundamental and translational cancer research

Single-cell functional proteomics assays can connect genomic information to biological function through quantitative and multiplex protein measurements. Tools for single-cell proteomics have developed rapidly over the past 5 years and are providing unique opportunities. This thesis describes an emerging microfluidics-based toolkit for single cell functional proteomics, focusing on the development of the single cell barcode chips (SCBCs) with applications in fundamental and translational cancer research.

The microchip designed to simultaneously quantify a panel of secreted, cytoplasmic and membrane proteins from single cells will be discussed at the beginning, which is the prototype for subsequent proteomic microchips with more sophisticated design in preclinical cancer research or clinical applications. The SCBCs are a highly versatile and information rich tool for single-cell functional proteomics. They are based upon isolating individual cells, or defined number of cells, within microchambers, each of which is equipped with a large antibody microarray (the barcode), with between a few hundred to ten thousand microchambers included within a single microchip. Functional proteomics assays at single-cell resolution yield unique pieces of information that significantly shape the way of thinking on cancer research. An in-depth discussion about analysis and interpretation of the unique information such as functional protein fluctuations and protein-protein correlative interactions will follow.

The SCBC is a powerful tool to resolve the functional heterogeneity of cancer cells. It has the capacity to extract a comprehensive picture of the signal transduction network from single tumor cells and thus provides insight into the effect of targeted therapies on protein signaling networks. We will demonstrate this point through applying the SCBCs to investigate three isogenic cell lines of glioblastoma multiforme (GBM).

The cancer cell population is highly heterogeneous with high-amplitude fluctuation at the single cell level, which in turn grants the robustness of the entire population. The concept that a stable population existing in the presence of random fluctuations is reminiscent of many physical systems that are successfully understood using statistical physics. Thus, tools derived from that field can probably be applied to using fluctuations to determine the nature of signaling networks. In the second part of the thesis, we will focus on such a case to use thermodynamics-motivated principles to understand cancer cell hypoxia, where single cell proteomics assays coupled with a quantitative version of Le Chatelier's principle derived from statistical mechanics yield detailed and surprising predictions, which were found to be correct in both cell line and primary tumor model.

The third part of the thesis demonstrates the application of this technology in the preclinical cancer research to study the GBM cancer cell resistance to molecular targeted therapy. Physical approaches to anticipate therapy resistance and to identify effective therapy combinations will be discussed in detail. Our approach is based upon elucidating the signaling coordination within the phosphoprotein signaling pathways that are hyperactivated in human GBMs, and interrogating how that coordination responds to the perturbation of targeted inhibitor. Strongly coupled protein-protein interactions constitute most signaling cascades. A physical analogy of such a system is the strongly coupled atom-atom interactions in a crystal lattice. Similar to decomposing the atomic interactions into a series of independent normal vibrational modes, a simplified picture of signaling network coordination can also be achieved by diagonalizing protein-protein correlation or covariance matrices to decompose the pairwise correlative interactions into a set of distinct linear combinations of signaling proteins (i.e. independent signaling modes). By doing so, two independent signaling modes – one associated with mTOR signaling and a second associated with ERK/Src signaling have been resolved, which in turn allow us to anticipate resistance, and to design combination therapies that are effective, as well as identify those therapies and therapy combinations that will be ineffective. We validated our predictions in mouse tumor models and all predictions were borne out.

In the last part, some preliminary results about the clinical translation of single-cell proteomics chips will be presented. The successful demonstration of our work on human-derived xenografts provides the rationale to extend our current work into the clinic. It will enable us to interrogate GBM tumor samples in a way that could potentially yield a straightforward, rapid interpretation so that we can give therapeutic guidance to the attending physicians within a clinical relevant time scale. The technical challenges of the clinical translation will be presented and our solutions to address the challenges will be discussed as well. A clinical case study will then follow, where some preliminary data collected from a pediatric GBM patient bearing an EGFR amplified tumor will be presented to demonstrate the general protocol and the workflow of the proposed clinical studies.

No caminho da cidadania...

No pós-guerra iniciou-se um processo de internalização política dos direitos fundamentais das mulheres com base na Declaração Universal dos Direitos do Homem, (10 de dezembro de 1948), onde são enaltecidos direitos e valores como a Liberdade e a Igualdade. A adoção da Declaração por parte de países democráticos, como o caso de Portugal, conduziu ao exercício de cidadania plena, independentemente do género, da raça e da religião. Assim, a não discriminação tornou-se um princípio a aplicar nas esferas familiares, públicas e laborais. Tal significa, por exemplo, partilha de tarefas domésticas entre homens e mulheres, participação na vida comunitária e iguais oportunidades laborais. Mas foram superadas as discriminações? Que se passa a nível laboral? A presente dissertação resulta de uma investigação sobre a situação laboral das mulheres em serviços onde constitucionalmente usufruem dos mesmos direitos que os seus colegas homens. Incide sobre os serviços públicos, privados e empresas de Ponte de Sor e tem por referencial o III Plano Nacional para a Igualdade de Cidadania e Género (2007/2010), cuja principal linha orientadora é "o aprofundamento de atividade política e de realidade social (gendermainstreaming)" (2007, p.l5). Com a realização deste estudo concretizámos um trabalho constituído por 3 capítulos, onde se constata que “No Caminho da Cidadania..." é um processo lento. No primeiro capítulo procurou-se abordar a origem histórica do conceito de cidadania e no capítulo segundo tratou­ se da relação da mulher com o trabalho e o poder. O terceiro capítulo, e último, dá conta dos resultados de questionários realizados em Ponte de Sor, nos serviços públicos e privados, e empresas. A conclusão revela a perplexidade causada pela quase indiferença em relação às questões de género nos Serviços questionados em Ponte de Sor. SUMMARY: After World War I began a process of political antinationalization of the women fundamental rights based on the Universal Declaration of the Human Rights, (1Oth December 1948), where rights and values like liberty and equality are exalted. The adoption of the Declaration by the democratically countries, like Portugal, leaded to the execution of full citizenship, independently of gender, race and religion. Therefore, nondiscrimination became a principle to apply in the family, public and labor spheres. This means, for example, share of domestic tasks between men and women, participation in the communal life, and equal opportunities of labor. But were the discriminations surpassed? What is going on the labor level This dissertation results from an inquiry about the labor situation of women in service where constitutionally make uses of the same rights as their colleague’s men. It reflects on the public, private and companies of Ponte de Sor which has for yardstick the III National Plan for Equality of Citizenship and Gender (2007/2010), whose mainline adviser is "the political activity and the social reality deepening (gender mainstreaming)" (2007, p.15). Through this study we fixed a work constituted by three chapters, where it established that "On the Path of Citizenship ..." is a slow process. ln the first chapter tried to broach the historical origin of the concept of citizenship and in the second paragraph was approached the relation of women with labor and power. The third, and last, chapter tries to show the results of questionnaires carried out in Ponte de Sor, in the public, private services and companies. The conclusion reveals the perplexity caused by the barely indifference regarding the questions of genre in the Services questioned in Ponte de Sor.

Evasão na educação profissional : estudo de caso de estudantes com necessidades específicas no Campus Taguatinga do Instituto Federal de Brasília

Dissertação apresentada para obtenção do grau de mestre do Mestrado em Educação Social e Intervenção Comunitária da Escola Superior de Educação do Instituto Politécnico de Santarém