985 resultados para ToF-SIMS, PLS, multivariate Analyse, funktionalisierte Oberflächen


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Magdeburg, Univ., Fak. für , Diss., 2011

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DBM, schizophrenia, morphometry, computational neuroanatomy

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Climate change, Sylt, key persons, participating groups, perception, social representations, semistructured open interview, analysis of frequency, analysis of homogenety, contextualization

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Close homolog of L1, neural cell recognition molecules, c-fos, arg3.1, arc, immediat early genes, novelty, information processing, behavioral tests

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Managed Care, physicians' behavior, primary practice, efficiency, econometric analysis

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Magdeburg, Univ., Medizin. Fakultät, Diss., 2008

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Magdeburg, Univ., Fak. für Mathematik, Diss., 2011

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Androgen receptor gene; FISH; DICE1; promoter; expression; hypermethylation; prostate cancer

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Color image processing, pattern recognition, machine vision, application

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Background: Several researchers seek methods for the selection of homogeneous groups of animals in experimental studies, a fact justified because homogeneity is an indispensable prerequisite for casualization of treatments. The lack of robust methods that comply with statistical and biological principles is the reason why researchers use empirical or subjective methods, influencing their results. Objective: To develop a multivariate statistical model for the selection of a homogeneous group of animals for experimental research and to elaborate a computational package to use it. Methods: The set of echocardiographic data of 115 male Wistar rats with supravalvular aortic stenosis (AoS) was used as an example of model development. Initially, the data were standardized, and became dimensionless. Then, the variance matrix of the set was submitted to principal components analysis (PCA), aiming at reducing the parametric space and at retaining the relevant variability. That technique established a new Cartesian system into which the animals were allocated, and finally the confidence region (ellipsoid) was built for the profile of the animals’ homogeneous responses. The animals located inside the ellipsoid were considered as belonging to the homogeneous batch; those outside the ellipsoid were considered spurious. Results: The PCA established eight descriptive axes that represented the accumulated variance of the data set in 88.71%. The allocation of the animals in the new system and the construction of the confidence region revealed six spurious animals as compared to the homogeneous batch of 109 animals. Conclusion: The biometric criterion presented proved to be effective, because it considers the animal as a whole, analyzing jointly all parameters measured, in addition to having a small discard rate.

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EMC, EDM, spark, power electronics, modeling, radiation

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Charitable giving, fiscal effect, income elasticity, income tax, marginal tax rate, price elasticity

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Distance learning, Canadian educational system, institution, medial learning, school system Saxony-Anhalt, system theory, qualitative research