Análise sensorial como ferramenta útil no desenvolvimento de cosméticos

In assessing the quality of cosmetics, sensory analysis has an undisputed role as a tool of scientific measurement, since no analytical tool is capable of replacing the human senses. In product development, sensory analysis is a uniquely useful tool to measure consumer acceptance. The objective of this paper is to present a critical review of the issue based on published papers and sensory test results obtained by our research group, which can assist cosmetics development.

Estudo da segurança de cosméticos: Presente e futuro

Cosmetics have been used since ancient times and, recently, their consumption has increased greatly in many countries, including brazil, which is the third largest consumer market in the world. Thus, concern for the safety and efficacy of these products should be heightened, even though these products are rarely related to adverse reactions that damage the health. Brazilian law requires manufacturers to subject their products to safety testing, to assess the possible reactions that could be caused by them (irritation, sensitization, systemic effects). To this end, in general, animals have been used as the experimental model, but this practice is being increasingly controlled, so that the scientific community is looking for alternative tests that do not require experimental in vivo models. Thus, this review aims to describe the main biological assays used to assess the safety of cosmetics, as well as in vitro assays that can replace them.

Chlorine disinfection of dye wastewater: Implications for a commercial azo dye mixture

Azo dyes, the most widely used family of synthetic dyes, are often employed as colorants in areas such as textiles, plastics, foods/drugs/cosmetics, and electronics. Following their use in industrial applications, azo dyes have been found in effluents and various receiving waters. Chemical treatment of effluents containing azo dyes includes disinfection using chlorine, which can generate compounds of varying eco/genotoxicity. Among the widely known commercial azo dyes for synthetic fibers is C.I. Disperse Red 1. While this dye is known to exist as a complex mixture, reports of eco/genotoxicity involve the purified form. Bearing in mind the potential for adverse synergistic effects arising from exposures to chemical mixtures, the aim of the present study was to characterize the components of commercial Disperse Red 1 and its chlorine-mediated decoloration products and to evaluate their ecotoxicity and mutagenicity. In conducting the present study, Disperse Red 1 was treated with chlorine gas, and the solution obtained was analyzed with the aid of LC-ESI-MS/MS to identify the components present, and then evaluated for ecotoxicity and mutagenicity, using Daphnia similis and Salmonella/microsome assays, respectively. The results of this study indicated that chlorination of Disperse Red 1 produced four chlorinated aromatic compounds as the main products and that the degradation products were more ecotoxic than the parent dye. These results suggest that a disinfection process using chlorine should be avoided for effluents containing hydrophobic azo dyes such commercial Disperse Red 1. © 2012 Elsevier B.V..

Como desenhar e escrever um protocolo de pesquisa clínica em Cosmiatria

Cosmetic Dermatology is a growing subspecialty. High-quality basic science studies have been published; however, few double-blind, randomized controlled clinical trials, which are the major instrument for evidence-based medicine, have been conducted in this area. Clinical research is essential for the discovery of new knowledge, improvement of scientific basis, resolution of challenges, and good clinical practice. Some basic principles for a successful researcher include interest, availability, persistence, and honesty. It is essential to learn how to write a protocol research and to know the international and national regulatory rules. A complete clinical trial protocol should include question, background, objectives, methodology (design, variable description, sample size, randomization, inclusion and exclusion criteria, intervention, efficacy and safety measures, and statistical analysis), consent form, clinical research form, and references. Institutional ethical review board approval and financial support disclosure are necessary. Publication of positive or negative results should be an authors' commitment. © 2013 by Anais Brasileiros de Dermatologia.

Produtividade e acúmulo de nutrientes em plantas de jambu, sob adubação orgânica e mineral

The organic production is a system that allows achieving good levels of productivity, while avoiding the risks of chemical contamination of farmers, consumers and the environment. Because jambu plant is widely used as alternative medicine and cosmetics industries, has been increasing interest in its cultivation. The aim of this study was to analyze the biomass, accumulation of nutrient, productivity and determine the pesticide residue in plant jambu when grown under organic and mineral fertilization. The experiment was conducted at the Experimental Farm São Manuel, FCA / UNESP. The experiment was conducted at São Manuel Experimental Farm UNESP. The statistical was arranged in the randomized block design, in a 2 x 6 factorial scheme, two sources of fertilizers (organic and mineral) and six doses of nitrogen, with four replications. The characteristics evaluated were plant height, fresh and dry weight, nutrients of accumulation in shoots and productivity. Mineral fertilizer gave higher biomass, productivity and accumulation of N and K in relation to organic fertilizer used. It is recommended the dose of 90g m -2 of urea as appropriate to obtain these results. However the organic fertilization favored the accumulation of phosphorus in plants jambu in relation the mineral fertilizer, and the dose of 10 kg m-2 of cattle manure recommended to achieve this result in plants jambu. We did not detect the presence of phosphorous and carbamate on leaves of jambu under organic and mineral fertilization. However, we observed the presence of chlorine in the leaves used for the two fertilizations.

Validation of an alternative analytical method for the quantification of antioxidant activity in plant extracts

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Thermal behavior of coffee oil (Robusta and Arabica species)

Coffee seeds are a source for obtaining oil which is used in the candy, soluble coffee, and cosmetics industries. The main purpose of this study was the investigation of the lipid profile and thermal behavior of the roasted and in nature coffee oil of Arabica and Robusta species, using thermogravimetry, differential thermal analysis, derivative thermogravimetry, differential scanning calorimetry (DSC), and modulated DSC. Details concerning the thermal decomposition as well as data of the kinetic parameters have been described here. The kinetic studies were evaluated from several heating rates with a sample mass of 10 mg in open crucible under nitrogen atmospheres. The obtained data were evaluated with the isoconversional kinetic method, where the values of activation energy (Ea/kJ mol-1) were evaluated in function of the conversion degree (α). In addition, this oil was evaluated by modulated DSC from 25 to -60 °C, where the transition phase behavior was verified. © 2013 Akadémiai Kiadó, Budapest, Hungary.

Caracterização bioquímica de uma serino-protease produzida pelo fungo termofílico Myceliophthora sp

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo da atividade antioxidante em frutas nativas e exóticas brasileiras

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Caracterização bioquímica e centesimal das espécies Astrocaryum vulgare Mart. (tucumã) e Endopleura uchi (Huber) Cuatrec. (uxi) nativas da região Amazônica

Pós-graduação em Biotecnologia - IQ

Desenvolvimento de cosmético contendo ácido Alfa-Lipóico para prevenção de alterações da pele e do envelhecimento cutâneo

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Influência da associação de filtros solares sobre a estabilidade, liberação, permeação e retenção cutânea do p-metoxicinamato de octila em formulações fotoprotetoras

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo farmacognóstico e avaliação da atividade antimicrobiana e citotóxica de preparações cosméticas contendo o extrato de folhas de Myrciaria cauliflora O. Berg. (Myrtaceae) e de casca de Stryphnodendron adstrigens (Mart.)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Efeito alelopático de extrato de leonurus sibiricus l. em mentha piperita l.. desenvolvimento, trocas gasosas e metabólitos do óleo essencial

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Caracterização dos ácidos graxos das sementes e compostos voláteis dos frutos de espécies do gênero Passiflora

Pós-graduação em Agronomia (Horticultura) - FCA