Profils de prise en charge médicale chez les enfants et adolescents traités par antidépresseurs : effet des mises en garde réglementaires et publications de guides de pratique clinique

Suite aux notifications de cas de comportements suicidaires associés aux antidépresseurs (ADs) chez les jeunes, une mise en garde réglementaire a été émise en mai 2004 au Canada, et deux guides de pratique clinique ont été publiés dans la littérature en novembre 2007. L'objectif de ce mémoire fut d'évaluer l’association entre ces interventions de communication et le suivi médical de la population pédiatrique traitée par ADs au Québec. Une étude de cohorte rétrospective (1998-2008) a été menée chez 4 576 enfants (10-14 ans) et 12 419 adolescents (15-19 ans) membres du régime public d’assurance médicaments du Québec, ayant débuté un traitement par AD. Le suivi médical dans les trois premiers mois de traitement a été mesuré par l’occurrence et la fréquence de visites médicales retrouvées dans les banques de données de la RAMQ. Les facteurs associés à un suivi conforme aux recommandations ont été évalués à partir de modèles de régression logistique multivariés. Seuls 20% des enfants ou adolescents ont eu au moins une visite de suivi à chaque mois, en conformité avec les recommandations. La probabilité de recevoir un suivi médical conforme était plus élevée lorsque le prescripteur initial était un psychiatre. L’occurrence et la fréquence des visites n’ont pas changé après la publication de la mise en garde ou des recommandations. De ce mémoire on conclut que d'autres interventions visant à optimiser le suivi médical devraient être envisagées.

Diffuser en libre accès: une habitude à prendre pour maximiser l’impact de vos publications!

Quels sont les avantages et inconvénients de la publication en libre accès? Quelles sont les revues de médecine dentaire qui autorisent le dépôt d’une copie d’un article publié dans Papyrus afin qu’il soit disponible à tous? Certaines versions d’un article (prépublication, version révisée par les pairs, version finale mise en page par l’éditeur) peuvent être auto-archivées dans Papyrus pour respecter à la fois la politique de l’éditeur et celle de l’organisme qui a subventionné la recherche. De plus, les Bibliothèques de l’UdeM peuvent faire une partie des démarches du dépôt pour vous!

How to measure the internationality of scientific publications

Resumen tomado de la publicaci??n

Identification of quality in educational research publications : the european educational research quality indicators (EERQI) project

Resumen basado en el de la publicación

‘Les puissances nucléaires officielles: entre désarmement et prolifération’

Review of the posture of the declared nuclear weapon states with regard to their own commitment to nuclear disarmament as contained in the Non-Proliferation Treaty and their shared fear of nuclear proliferation

Quantitative analysis of indexed publications on seventeen model organisms in nine countries, from 1974 to 2006

Developed countries have an even distribution of published papers on the seventeen model organisms. Developing countries have biased preferences for a few model organisms which are associated with endemic human diseases. A variant of the Hirsch-index, that we call the mean (mo)h-index (""model organism h-index""), shows an exponential relationship with the amount of papers published in each country on the selected model organisms. Developing countries cluster together with low mean (mo)h-indexes, even those with high number of publications. The growth curves of publications on the recent model Caenorhabditis elegans in developed countries shows different formats. We also analyzed the growth curves of indexed publications originating from developing countries. Brazil and South Korea were selected for this comparison. The most prevalent model organisms in those countries show different growth curves when compared to a global analysis, reflecting the size and composition of their research communities.

Listing of Faculty Publications, Spring 1982

The Library Media Resources Center is happy to publish this revised Listing of Faculty Publications. As you recall, the first edition was issued in 1979 and so, 2 1/2 years later, it is our pleasure to present a larger and more complete edition... Special thanks to Professor Albert Talero who did all the editing and arrangements for the publication. Thanks also to Professor Fred Low for making the TRS-80 wordprocessing facilities of the LaGuardia Automated Library System (LALS) available for this edition. --Ngozi Agbim, April 23, 1982; 51 p.

Listing of Faculty Publications, Spring 1985

The Library-Media Resources Center is pleased to present you with the most recent edition of the LaGuardia Listing of Faculty Publications. In it you will find proof of the vitality and commitment to scholarship of the LaGuardia Faculty. You will also see the diversity of interests and expertise of your colleagues…Thanks also to Dorothy Lopez and Eddie Greissle, who labored long hours at the microcomputer reaping this bumper crop of information. –Al Talero, April 10, 1985; 63 p.

Power-law distributions for the citation index of scientific publications and scientists

The number of citations of a scientific publication or of an individual scientist has become an important factor of quality assessment in science. We report a study of the statistical distribution of the citation index of both scientific publications and scientists. We give numerical evidence that Tsallis (power law) statistics explains the entire distribution over eight orders of magnitude (10-4 to 10(4)). Also, we draw Zipf plots in order to analyze the statistical distribution of the citation index of Brazilian and international physicists and chemists. The relatively small group of Brazilian scientists seems more adequate to explain the dynamics of the citation index. In this case, we find that the distribution of the citation index can also be explained by a gradually truncated power law with similar parameters. We finally discuss possible mechanisms behind the citation index of scientists and scientific publications.

Clinical research on new drugs (Phase I). Profile of scientific publications: data from the pre-clinical phase and bioethical aspects

OBJETIVO: Traçar o perfil das publicações científicas de fase I e procurar saber se a publicação oferece dados da fase pré-clínica com ênfase nos aspectos bioéticos. MÉTODOS: Foram analisados 61 artigos científicos publicados no ano de 2007, que relatam pesquisas envolvendo seres humanos com novos fármacos, medicamentos ou vacinas em fase I. Foi elaborado um roteiro para coleta de dados, com o qual fosse possível analisar e avaliar os artigos científicos. O roteiro contempla itens referentes à fase pré-clínica (associados à fase clínica) e itens referentes às características da amostra. RESULTADOS: Nos artigos analisados, a maioria das pesquisas foi realizada nos EUA. Devido ao grande número de publicações destinadas às doenças oncológicas a maioria delas foi realizada com voluntários doentes. Quanto às informações sobre a fase pré-clínica presente nas publicações de fase I observamos que são pobres ou inexistentes. Mesmo que os autores julguem a pesquisa fase I como promissora e sugiram estudos futuros de fase II, ao leitor não é possível este mesmo julgamento pela escassez de informações da fase pré-clínica. CONCLUSÃO: O perfil das publicações levanta dados que merecem reflexão e análise para melhor avaliação do que está ocorrendo com as publicações de fase I.