Crit��rios compostos para delineamentos ��timos robustos

P��s-gradua����o em Biometria - IBB

Avalia����o do processo de produ����o de cefamicina C por Streptomyces clavuligerus

P��s-gradua����o em Biotecnologia - IQ

Din��mica do metabolismo micromolecular da cana-de-a����car em resposta �� infec����o com o fungo Puccinia kuehnii (ferrugem alaranjada)

P��s-gradua����o em Qu��mica - IQ

Influ��ncia da aplica����o de ultrassom em desidrata����o osm��tica de carne bovina

Funda����o de Amparo �� Pesquisa do Estado de S��o Paulo (FAPESP)

Filtros UV na ��gua de abastecimento p��blico na regi��o da bacia hidrogr��fica tiet��-jacar��: desenvolvimento de m��todo, estudo de ocorr��ncia e concentra����es ambientais

Coordena����o de Aperfei��oamento de Pessoal de N��vel Superior (CAPES)

Investiga����o qu��mica e biol��gica dos metab��litos secund��rios derivados de macroalgas marinhas e microrganismos associados

P��s-gradua����o em Qu��mica - IQ

Modelagem e otimiza����o por metodologia de superf��cies de resposta: um estudo em arames de a��o SAE 9254 para molas automobil��sticas

P��s-gradua����o em Engenharia Mec��nica - FEG

Produ����o da enzima ciclodextrina glicosil transferase por Bacillus circulans

As ciclodextrinas (CDs) s��o oligossacar��deos c��clicos que solubilizam e modificam mol��culas por possuir uma cavidade interna hidrof��lica e regi��o externa hidrof��bica, com uma estrutura tronco-c��nica, conferindo a estes a����cares c��clicos propriedades f��sico-qu��micas para complexa����o de uma grande variedade de mol��culas. A enzima ciclodextrina glicosiltransferase (CGTase) catalisa rea����es de convers��o de amido em diferentes tipos de CDs, a sua produ����o �� influenciada por v��rios fatores. As pesquisas dirigidas para a produ����o de CGTases de menor custo s��o importantes para viabilizar economicamente o uso das CDs em escala industrial. No presente estudo, as CDs foram produzidas a partir de diferentes fontes de carbono pelo micro-organismo Bacillus circulans ATCC 21783, estudou-se seu crescimento celular assim como sua produ����o enzim��tica, utilizando a ferramenta estat��stica de planejamento experimental. O micro-organismo Bacillus circulans ATCC 21783 mostrou-se ser eficiente na produ����o da enzima CGTase, os resultados indicaram a potencialidade do gr��o de sorgo como o melhor substrato para fermenta����o na produ����o de CGTase. Quanto maior o tamanho do gr��o de sorgo, maiores concentra����es de glicose e amido estar��o presentes, o que influencia diretamente a produ����o enzim��tica. Por meio do planejamento experimental foram proposto modelos matem��ticos que expressam tanto a produ����o enzim��tica quanto a concentra����o das vari��veis das concentra����es da fonte de carbono, pH e a temperatura. A import��ncia de desenvolver o modelo �� demonstrar a sua aplica����o bem-sucedida para determina����o das condi����es ideais que representam o processo de alta produtividade enzim��tica da CGTase. A otimiza����o das vari��veis foram obtidas a partir de quatro planejamentos experimentais composto central (PCC) e seus resultados analisados pelas superf��cies de resposta. Os melhores resultados do planejamento encontrados no...

Identifica����o de bact��rias l��ticas e otimiza����o da produ����o de ��cido l��tico

O objetivo deste trabalho foi identificar o micro-organismo Y15C previamente isolado no laborat��rio de microbiologia industrial, da UNESP de Rio Claro, utilizando t��cnicas bioqu��micas, al��m de otimizar a produ����o de ��cido l��tico por meio de fermenta����o batelada simples e batelada alimentada. Considerando o potencial do micro-organismo para a produ����o de D(-) ��cido l��tico, com 100% de pureza, is��mero usado na s��ntese de pol��meros empregados na produ����o de diversos materiais resistentes e biodegrad��veis, foi feita a otimiza����o do meio de cultura, tendo como fonte de carbono a manipueira. A manipueira por ser um res��duo do processamento da mandioca que cont��m grande quantidade de amido e quando hidrolisado pode ser uma fonte de carbono de baixo custo, quando utilizado pelo micro-organismo. O isolado Y15C foi identificado como Lactobacillus delbrueckii ssp delbrueckii, por meio de testes bioqu��micos. Em rela����o �� otimiza����o dos par��metros de fermenta����o, usando planejamento experimental, observou-se que a adi����o de componentes ao meio de cultivo, assim como a varia����o da temperatura n��o aumentou significamente a produ����o de ��cido l��tico. Desta forma optou-se por trabalhar com as menores concentra����es de AMM (1,6 mL/L) e citrato (0,96 g/L) e maior temperatura (43,4��C). Para que haja aumento na produ����o de ��cido l��tico podem ser realizados diversos tipos de fermenta����es, no caso deste trabalho foram comparados dois tipos de fermenta����o, batelada simples e batelada com alimenta����o constante. A maior concentra����o de ��cido l��tico (41,6 g/L) foi observada que quando utilizada fermenta����o do tipo de fermenta����o em batelada... (Resumo completo, clicar acesso eletr��nico abaixo)

Produ����o de hidrolisado enzim��tico de farinha de batata-doce para fermenta����o etan��lica

Recently there is a great quest of producing alcohol from starchy resources, replacing the sugar cane. The most common starchy sources are cassava, maize and sweet potatoes and a lot of research are been realized with excellent results. In this work it was evaluated the influence of the concentration of dry matter on the enzymatic hydrolysis process of starch from sweet potato for ethanol production. Through the sweet potato was produced a flour using a low-cost method and easy operation equipments. The sweet potato flour was characterized physical and chemically and from these results was prepared the treatments for enzymatic hydrolysis. The experimental design considered as independent variable the dry matter concentration of the sweet potato flour in 3 levels; 10, 15 and 20% in the formulation of suspensions. The other variables were keeping constant being: temperature in the 1�� hydrolysis step of 90��C and time of 2 hours; temperature in the 2�� saccharification step of 60��C and time of 17 hours. The hydrolysates obtained at the three assays were transferred to six liter enlerynmeyer and inoculated with a biologic catalyst, Saccharomyces, dehydrated yeasts of Saccharomyces cerevisiae CAT 1, at a rate of 5% in weight. The flasks were placed in a shaker type orbital with controlled temperature of 30��C during a time of 15 hours. The initial reducer sugars concentration and respective ethanol concentrations in wine were: 11.2% glucose and 2.16% ethanol in the suspension with 10% of dry matter; 13.5% glucose and 4.39% ethanol with 15% and 17.5% glucose and 6.03% ethanol in suspension with 20% of dry matter. ix The results showed that the higher percentage of dry matter carried out to higher sugar yield in hydrolyzed. It was possible observed that products quality improved with a higher concentration of dry matter

Aplica����o do m��todo desirability para otimiza����o de processo com m��ltiplas respostas

Currently, the competition between organizations in the pursuit of consumer preference has become increasingly fierce. In addition, consumers have become increasingly demanding due to high speed with which innovations occur, leaving the companies meet and sometimes surpass those expectations In this context, there is the necessity to use methods as mathematical models capable of dealing with the optimization of multiple responses simultaneously. In this context, this study presents an application of techniques of Design of Experiment in a machining process of a NIMONIC 80 alloy, a ���superalloy��� that has thermal and mechanical properties that make its machining difficult and in order to do this, the Desirability Function was used. As they are determining conditions in the machining capability of the alloy, the roughness and the cutting length were considered as variable settings, and the factors that can influence them are cutting speed, feed rate, cutting depth, inserts type and lubrication. The analysis of the result pointed out how was the influence of all factors on each response and also showed the efficiency and reliability of the method

As atividades experimentais no ensino de f��sica

This work was developed from a literature search in order to provide teachers of physics theoretical and methodological requirements for the use of experimentation in physics teaching, with the aim of contributing to the teaching practice of these teachers and, consequently, for improving teaching this discipline. Therefore, to deal in the course of this research, the goals and types of practical activities, new information and communication technologies that fit the experimental approaches and the role of the teacher in this context, specifying the variables that influence and relate with experimental activities. Studies are presented on the methodology and planning of experimental activities to draw attention to the teacher and the important issues relevant to the preparation of these activities as, for example, the proposed objectives and types of discourse and existing approaches for the conduct of practical activities. In this sense, the trend is highlighted for walks where the approach of practical activities, within the context of practices interactionist and are pointed out strengths and weaknesses of different types of activities presented. We also highlight aspects of the learning process associated with some theoretical reference that are on that subject, as Piaget, Vigotski and Ausubel, so that the teacher can apply the concepts in their theories worked in the practical lessons of physics

M��todo de Taguchi aplicado a um processo de corte por fus��o de um tecido sint��tico

A company must have full knowledge and control of its operations so as to meet the market requirements and meet their production goals. Thus this paper uses the Taguchi method to extend the operational control of a cutting process by fusion of a synthetic fabric in the longitudinal direction. For process analysis and tracking of possible causes of the problem techniques of Production Engineering as the cause and effect diagram, also known as Ishikawa diagram, and design of experiments were used, the last one was applied to the design techniques of Taguchi. Finally the preparation method of understanding and design of experiment was due to the use of the software MINITAB v15 ��, which showed that the speed of rolling the fabric after cutting is crucial for controlling the entire operation

A utiliza����o de modelos matem��ticos para a otimiza����o de processos

This dissertation has as main theme the discuss about how the use of mathematical models for process optimization. The current scenario of strong competition to conquer the consumer market necessitates the development of improvements to better performance of the process as a whole, is to reduce costs, increase efficiency or effectiveness. Thus, the use of methodologies to assist in this process is becoming increasingly viable. Methodologies developed in the past are being studied and improved. An example is the Desirability, the object of the present study, which was developed in the 80's and has been improved over time. To understand and study this methodology was applied to the desirability function in three instances, where it was used Design of Experiments (DOE), taken from scientific papers, using the Solver tool (Excel ��) and desirability (Minitab ��). Thus, in addition to studying the methodology, it was possible to compare the performance of tools used for optimization in different situations. From the results of this study, it was possible to validate the superiority of one of the models studied compared fairly

Otimiza����o do processo de usinagem da superliga nimonic 80A utilizando o M��todo de Taguchi

Atualmente, atender as necessidades dos consumidores �� uma das metas mais importantes, os consumidores est��o em busca de produtos com qualidade e pre��os mais acess��veis, para isso, �� indispens��vel que as empresas se atualizem para melhorar seus produtos e servi��os. Com este cen��rio, as superligas est��o cada vez mais ganhando mercado, pois possuem ��timas propriedades, principalmente em rela����o a operar em temperaturas elevadas, podendo proporcionar maior efici��ncia para motores que necessitam trabalhar em altas temperaturas. Em contra partida a essa vantagem, as superligas possuem uma baixa usinabilidade, sendo importante a an��lise do processo de usinagem para se tornarem mais aplic��veis. Este trabalho visa �� otimiza����o do processo de torneamento cil��ndrico da superliga Nimonic 80A, com o intuito de melhorar a qualidade do produto, utilizando o M��todo de Taguchi, com o arranjo ortogonal L16, sendo o comprimento de corte definido como vari��vel resposta e analisados seis fatores que poderiam influenciar na sua varia����o, tais fatores s��o: velocidade de corte, avan��o, profundidade de corte, tipo de pastilha, lubrifica����o e dureza do material. Os resultados obtidos demonstraram que os fatores avan��o, tipo de pastilha e lubrifica����o s��o significativos e exercem influencia no processo, sendo que o avan��o deve ser ajustado no n��vel de 0,12 mm/rev, a pastilha a ser utilizada deve ser CP250 e a lubrifica����o deve ser feita de maneira abundante, para a otimiza����o do processo. Com a an��lise dos resultados, tamb��m podemos observar a efici��ncia e confiabilidade do m��todo utilizado, mostrando resultados coerentes