The charge of ignorance and misrepresentation proved against George B. Cheever. From the Salem Gazette.

Mode of access: Internet.

Review of the life and character of Lord Byron extracted from the British critic for April, 1831 ...

Mode of access: Internet.

The Interpretation of the scripture passage, the "more sure word of prophesy, &c.," 2 Peter, Chap. i., Verse 19, as given by George Fox, William Penn, Robert Barclay, George Whitehead, Francis Howgill, Samuel Fisher, and James Parnel in reply to opposers : also extracts from the writings of Ambrose Rigge, William Bayly, Charles Marshall, Josiah Coale, Margaret Fox, and Elizabeth Bathurst, on the same subject.

Cover title.

An abstract of the laws of Jamaica relating to slaves. (From 33 Charles II. [1681] to 59 George III. inclusive [1818]. With the slave law at length, also, an appendix, containing an abstract of the acts of Parliament relating to the abolition of the slave-trade.

Mode of access: Internet.

The speeches of Charles Phillips, esq., delivered at the bar, and on various public occasions in Ireland and England. To which is added, a letter to George IV.

First edition, London, 1817.

Record of the life and work of the Rev. Stephen Higginson Tyng and history of St. George's church, New York, to the close of his rectorship,

Mode of access: Internet.

Maryland in Liberia : a history of the colony planted by the Maryland State Colonization Society under the auspices of the State of Maryland, U.S., at Cape Palmas on the south-west coast of Africa, 1833-1853 : a paper read before the Maryland Historical Society, March 9th, 1885 /

Includes index.

A lecture before the Boston Young men's society, on the subject of lotteries. Delivered March 12, 1833.

Mode of access: Internet.

Life and letters of Mary Josephine Mason Remey, wife of Rear Admiral George Collier Remey, daughter of Chief Justice Charles Mason, 1845-1938;

"Copy ... "

The English home, from Charles I. to George IV.; its architecture, decoration and garden design,

"List of subscribers" ([15] p.) inserted between p. [iv] and v.

The life and letters of Lady Sarah Lennox, 1745-1826, daughter of Charles, 2nd Duke of Richmond, and successively the wife of Sir Thomas Charles Bunbury, Bart., and of the Hon. George Napier; also a short political sketch of the years 1760 to 1763,

Mode of access: Internet.

Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

The major histocompatibility complex (MHC) on chromosome 6 is associated with susceptibility to more common diseases than any other region of the human genome, including almost all disorders classified as autoimmune. In type 1 diabetes the major genetic susceptibility determinants have been mapped to the MHC class II genes HLA-DQB1 and HLA-DRB1 (refs 1–3), but these genes cannot completely explain the association between type 1 diabetes and the MHC region4, 5, 6, 7, 8, 9, 10, 11. Owing to the region's extreme gene density, the multiplicity of disease-associated alleles, strong associations between alleles, limited genotyping capability, and inadequate statistical approaches and sample sizes, which, and how many, loci within the MHC determine susceptibility remains unclear. Here, in several large type 1 diabetes data sets, we analyse a combined total of 1,729 polymorphisms, and apply statistical methods—recursive partitioning and regression...

Genetic studies of body mass index yield new insights for obesity biology

Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass index (BMI), a measure commonly used to define obesity and assess adiposity, in up to 339,224 individuals. This analysis identifies 97 BMI-associated loci (P < 5 × 10−8), 56 of which are novel. Five loci demonstrate clear evidence of several independent association signals, and many loci have significant effects on other metabolic phenotypes. The 97 loci account for ~2.7% of BMI variation, and genome-wide estimates suggest that common variation accounts for >20% of BMI variation. Pathway analyses provide strong support for a role of the central nervous system in obesity susceptibility and implicate new genes and pathways, including those related to synaptic function, glutamate signalling, insulin secretion/action, energy metabolism, lipid biology and adipogenesis.

Myer S. Isaacs collection undated, 1844, 1851-1925

Contains correspondence and newspaper clippings relating to the centennial birthday celebration of and memorial services for Sir Moses Montefiore; correspondence consists primarily of replies to a circular advocating the holding of memorial services issued by the Board of Delegates on Civil and Religious Rights from congregations in Buffalo, Charleston, Chicago, Cincinnati, Cleveland, and Detroit. Contains also correspondence relating to the activities of the Alliance Israelite Universelle on behalf of Palestine and the Jews in the Balkan States and Morocco and to the establishment of United States committees for the Alliance and the raising of funds, including correspondence with H. Pereira Mendes, Henry S. Jacobs, John Hay, and Adolphe Cremieux as well as letters from Baltimore, Cleveland, Detroit, Galveston, Minneapolis, Mobile, Rochester, St. Louis, and San Francisco. Also contains extensive correspondence concerning anti-semitism in Russia, aid to Jewish immigrants, and Jewish agricultural colonies in the United States, with letters from James G. Blaine, Manuel Augustus Kursheedt, Sabato Morais, Charles Nathan, Hirsch Leib Sabsovich, (Isaac N.?) Seligman and Judah Wechsler, among others. Also contains newspaper clippings and other items relating to Jewish life during the late 19th century and articles and memorabilia about various members of the Isaacs family.

Genetic studies of body mass index yield new insights for obesity biology

Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass index (BMI), a measure commonly used to define obesity and assess adiposity, in up to 339,224 individuals. This analysis identifies 97 BMI-associated loci (P < 5 × 10(-8)), 56 of which are novel. Five loci demonstrate clear evidence of several independent association signals, and many loci have significant effects on other metabolic phenotypes. The 97 loci account for ∼2.7% of BMI variation, and genome-wide estimates suggest that common variation accounts for >20% of BMI variation. Pathway analyses provide strong support for a role of the central nervous system in obesity susceptibility and implicate new genes and pathways, including those related to synaptic function, glutamate signalling, insulin secretion/action, energy metabolism, lipid biology and adipogenesis.