Luminosity profiles of advanced mergers of galaxies using 2MASS data

A sample of 27 disturbed galaxies that show signs of interaction but have a single nucleus were selected from the Arp and the Arp-Madore catalogues. For these, the Ks band images from the Two Micron All Sky Survey (2MASS) are analysed to obtain their radial luminosity pro�les and other structural parameters. We �nd that in spite of their similar optical appearance, the sample galaxies vary in their dynamical properties, and fall into two distinct classes. The �rst class consists of galaxies which can be described by a single r1=4 law and the second class consists of galaxies that show an outer exponential disk. A few galaxies that have disturbed pro�les cannot be �t into either of the above classes. However, all the galaxies are similar in all other parameters such as the far-infrared colours, the molecular hydrogen content and the central velocity dispersion. Thus, the dynamical parameters of these sets seem to be determined by the ratio of the initial masses of the colliding galaxies. We propose that the galaxies in the �rst class result from a merger of spiral galaxies of equal masses whereas the second class of galaxies results from a merger of unequal mass galaxies. The few objects that do not fall into either category show a disturbed luminosity pro�le and a wandering centre, which is indicative of these being unrelaxed mergers. Of the 27 galaxies in our sample, 9 show elliptical-like pro�les and 13 show an outer exponential. Interestingly, Arp 224, the second oldest merger remnant of the Toomre sequence shows an exponential disk in the outer parts.

An analysis of substitution, deletion and insertion mutations in cancer genes

Cancer-associated mutations in cancer genes constitute a diverse set of mutations associated with the disease. To gain insight into features of the set, substitution, deletion and insertion mutations were analysed at the nucleotide level, from the COSMIC database. The most frequent substitutions were c -> t, g -> a, g -> t, and the most frequent codon changes were to termination codons. Deletions more than insertions, FS (frameshift) indels more than I-F (in-frame) ones, and single-nucleotide indels, were frequent. FS indels cause loss of significant fractions of proteins. The 5'-cut in FS deletions, and 5'-ligation in FS insertions, often occur between pairs of identical bases. Interestingly, the cut-site and 3'-ligation in insertions, and 3'-cut and join-pair in deletions, were each found to be the same significantly often (p < 0.001). It is suggested that these features aid the incorporation of indel mutations. Tumor suppressors undergo larger numbers of mutations, especially disruptive ones, over the entire protein length, to inactivate two alleles. Proto-oncogenes undergo fewer, less-disruptive mutations, in selected protein regions, to activate a single allele. Finally, catalogues, in ranked order, of genes mutated in each cancer, and cancers in which each gene is mutated, were created. The study highlights the nucleotide level preferences and disruptive nature of cancer mutations.

Environments of extended radio sources in the Australia Telescope Low-Brightness Survey

We present a study of the environments of extended radio sources in the Australia Telescope Low-Brightness Survey (ATLBS). The radio sources were selected from the ATLBS Extended Source Sample, which is a well defined sample containing the most extended of radio sources in the ATLBS sky survey regions. The environments were analysed using 4-m Cerro-Tololo Inter-American Observatory Blanco telescope observations carried out for ATLBS fields in the Sloan Digital Sky Survey r(') band. We have estimated the properties of the environments using smoothed density maps derived from galaxy catalogues constructed using these optical imaging data. The angular distribution of galaxy density relative to the axes of the radio sources has been quantified by defining anisotropy parameters that are estimated using a new method presented here. Examining the anisotropy parameters for a subsample of extended double radio sources that includes all sources with pronounced asymmetry in lobe extents, we find good evidence for environmental anisotropy being the dominant cause for lobe asymmetry in that higher galaxy density occurs almost always on the side of the shorter lobe, and this validates the usefulness of the method proposed and adopted here. The environmental anisotropy parameters have been used to examine and compare the environments of Fanaroff-Riley Class I (FRI) and Fanaroff-Riley Class II (FRII) radio sources in two redshift regimes (z < 0.5 and z > 0.5). Wide-angle tail sources and head-tail sources lie in the most overdense environments. The head-tail source environments (for the HT sources in our sample) display dipolar anisotropy in that higher galaxy density appears to lie in the direction of the tails. Excluding the head-tail and wide-angle tail sources, subsamples of FRI and FRII sources from the ATLBS appear to lie in similar moderately overdense environments, with no evidence for redshift evolution in the regimes studied herein.

Revalidation of Natrix clerki Wall, 1925, an overlooked species in the genus Amphiesma Dumeril, Bibron & Dumeril, 1854 (Squamata: Natricidae)

Natrix clerki Wall, 1925, previously known from its sole holotype and considered a synonym of Amphiesma parallelum (Boulenger, 1890), is resurrected in the genus Amphiesma on the basis of the analysis of morphological variation in 28 specimens of ``Amphiesma parallelum'' auctorum, plus six living, unvouchered specimens discovered in Arunachal Pradesh and Nagaland, India, and one vouchered specimen from Talle Valley in Arunachal Pradesh. Specimens from northeast India (Nagaland), northern Myanmar, and China (Yunnan), previously identified as Amphiesma parallelum either in the literature or in museum's catalogues, are also here referred to A. clerki. The holotype of Amphiesma clerki is redescribed. As a consequence, the definition of Amphiesma parallelum is modified. A. parallelum inhabits the Khasi Hills and Naga Hills in Northeast India, whereas A. clerki has a wider range in the Eastern Himalayas, northern Myanmar and Yunnan (China). Amphiesma clerki differs from A. parallelum by its longer tail, dorsal scales more strongly keeled, scales of the first dorsal scale row strongly keeled vs. smooth, a postocular streak not interrupted at the level of the neck, and a much more vivid pattern on a darker background colour. Characters of species of the Amphiesma parallelum group, i.e. A. clerki, A. parallelum, A. bitaeniatum, A. platyceps and A. sieboldii are compared. A key to this group is provided.

Intensive Program ERASMUS: TOPCART. Geometric Documentation of the Heritage (administrative and academic documentation)

[EN] This academic activity has been the origin of other work that are also located in this repository. The first one is the dataset of information about the geometry of the Monastery recorded during the two years of fieldwork, then some bachelor thesis and papers are listed:

Assisting blog publication: annotation, model transformation, and crossblogging techniques

Although blogs exist from the beginning of the Internet, their use has considerablybeen increased in the last decade. Nowadays, they are ready for being used bya broad range of people. From teenagers to multinationals, everyone can have aglobal communication space.Companies know blogs are a valuable publicity tool to share information withthe participants, and the importance of creating consumer communities aroundthem: participants come together to exchange ideas, review and recommend newproducts, and even support each other. Also, companies can use blogs for differentpurposes, such as a content management system to manage the content of websites,a bulletin board to support communication and document sharing in teams,an instrument in marketing to communicate with Internet users, or a KnowledgeManagement Tool. However, an increasing number of blog content do not findtheir source in the personal experiences of the writer. Thus, the information cancurrently be kept in the user¿s desktop documents, in the companies¿ catalogues,or in another blogs. Although the gap between blog and data source can be manuallytraversed in a manual coding, this is a cumbersome task that defeats the blog¿seasiness principle. Moreover, depending on the quantity of information and itscharacterisation (i.e., structured content, unstructured content, etc.), an automaticapproach can be more effective.Based on these observations, the aim of this dissertation is to assist blog publicationthrough annotation, model transformation and crossblogging techniques.These techniques have been implemented to give rise to Blogouse, Catablog, andBlogUnion. These tools strive to improve the publication process considering theaforementioned data sources.

Authority files: Breaking out of the library silo to become signposts for research information

Authority files serve to uniquely identify real world ‘things’ or entities like documents, persons, organisations, and their properties, like relations and features. Already important in the classical library world, authority files are indispensable for adequate information retrieval and analysis in the computer age. This is because, even more than humans, computers are poor at handling ambiguity. Through authority files, people tell computers which terms, names or numbers refer to the same thing or have the same meaning by giving equivalent notions the same identifier. Thus, authority files signpost the internet where these identifiers are interlinked on the basis of relevance. When executing a query, computers are able to navigate from identifier to identifier by following these links and collect the queried information on these so-called ‘crosswalks’. In this context, identifiers also go under the name controlled access points. Identifiers become even more crucial now massive data collections like library catalogues or research datasets are releasing their till-now contained data directly to the internet. This development is coined Open Linked Data. The concatenating name for the internet is Web of Data instead of the classical Web of Documents.

Electron flow through cytochrome P450

The cytochromes P450 (P450s) are a remarkable class of heme enzymes that catalyze the metabolism of xenobiotics and the biosynthesis of signaling molecules. Controlled electron flow into the thiolate-ligated heme active site allows P450s to activate molecular oxygen and hydroxylate aliphatic C–H bonds via the formation of high-valent metal-oxo intermediates (compounds I and II). Due to the reactive nature and short lifetimes of these intermediates, many of the fundamental steps in catalysis have not been observed directly. The Gray group and others have developed photochemical methods, known as “flash-quench,” for triggering electron transfer (ET) and generating redox intermediates in proteins in the absence of native ET partners. Photo-triggering affords a high degree of temporal precision for the gating of an ET event; the initial ET and subsequent reactions can be monitored on the nanosecond-to-second timescale using transient absorption (TA) spectroscopies. Chapter 1 catalogues critical aspects of P450 structure and mechanism, including the native pathway for formation of compound I, and outlines the development of photochemical processes that can be used to artificially trigger ET in proteins. Chapters 2 and 3 describe the development of these photochemical methods to establish electronic communication between a photosensitizer and the buried P450 heme. Chapter 2 describes the design and characterization of a Ru-P450-BM3 conjugate containing a ruthenium photosensitizer covalently tethered to the P450 surface, and nanosecond-to-second kinetics of the photo-triggered ET event are presented. By analyzing data at multiple wavelengths, we have identified the formation of multiple ET intermediates, including the catalytically relevant compound II; this intermediate is generated by oxidation of a bound water molecule in the ferric resting state enzyme. The work in Chapter 3 probes the role of a tryptophan residue situated between the photosensitizer and heme in the aforementioned Ru-P450 BM3 conjugate. Replacement of this tryptophan with histidine does not perturb the P450 structure, yet it completely eliminates the ET reactivity described in Chapter 2. The presence of an analogous tryptophan in Ru-P450 CYP119 conjugates also is necessary for observing oxidative ET, but the yield of heme oxidation is lower. Chapter 4 offers a basic description of the theoretical underpinnings required to analyze ET. Single-step ET theory is first presented, followed by extensions to multistep ET: electron “hopping.” The generation of “hopping maps” and use of a hopping map program to analyze the rate advantage of hopping over single-step ET is described, beginning with an established rhenium-tryptophan-azurin hopping system. This ET analysis is then applied to the Ru-tryptophan-P450 systems described in Chapter 2; this strongly supports the presence of hopping in Ru-P450 conjugates. Chapter 5 explores the implementation of flash-quench and other phototriggered methods to examine the native reductive ET and gas binding events that activate molecular oxygen. In particular, TA kinetics that demonstrate heme reduction on the microsecond timescale for four Ru-P450 conjugates are presented. In addition, we implement laser flash-photolysis of P450 ferrous–CO to study the rates of CO rebinding in the thermophilic P450 CYP119 at variable temperature. Chapter 6 describes the development and implementation of air-sensitive potentiometric redox titrations to determine the solution reduction potentials of a series of P450 BM3 mutants, which were designed for non-native cyclopropanation of styrene in vivo. An important conclusion from this work is that substitution of the axial cysteine for serine shifts the wild type reduction potential positive by 130 mV, facilitating reduction by biological redox cofactors in the presence of poorly-bound substrates. While this mutation abolishes oxygenation activity, these mutants are capable of catalyzing the cyclopropanation of styrene, even within the confines of an E. coli cell. Four appendices are also provided, including photochemical heme oxidation in ruthenium-modified nitric oxide synthase (Appendix A), general protocols (Appendix B), Chapter-specific notes (Appendix C) and Matlab scripts used for data analysis (Appendix D).

Propuesta de catálogo para la selección de rodamientos de vuelco en aplicaciones cuasiestáticas

[ES]La propuesta de catálogo realizada en este proyecto, cuyo objetivo es convertirse en el catálogo de la empresa de rodamientos Iraundi S.A., constará de dos partes. La primera de ellas será una parte teórica e informativa que incluirá toda la información necesaria sobre la manipulación, montaje, mantenimiento y selección del tipo de rodamiento. Para ello se ha recabado información tanto del propio catálogo de Iraundi S.A., como de varios de los fabricantes de rodamientos más importantes del momento, como son INA, GOIMO, ROTHE-ERDE, y SKF. La segunda parte del catálogo lo formaran las tablas y gráficas de selección de rodamiento. Estas gráficas han sido renovadas con respecto al catálogo existente, y se ha tratado de conseguir unas gráficas que sean fáciles de interpretar, y que de manera sencilla se puedan obtener los tamaños y tipos de rodamiento adecuados, dependiendo de la aplicación de funcionamiento y de las fuerzas radiales, axiales y de momento que estos vayan a soportar. Éstas gráficas han sido calculadas exclusivamente para este proyecto, y validadas mediante la aplicación de elementos finitos, de los que finalmente se han obtenido unas gráficas que simplifican la selección óptima del rodamiento, y que tienen en cuenta el esfuerzo axial, radial, y momento que soportará el rodamiento, así como las fuerzas que serán capaces de soportar los tornillos empleados para el anclaje.

A bibliography of samplers for benthic invertebrates

This annotated bibliography covers literature to the end of November 1977, and includes references to samplers that could be used for the rapid removal of benthic invertebrates from natural substrata of rivers and streams. Marine samplers which have been, or could be, used in freshwater. Coverage of Russian literature is incomplete, although a selection of recent and important references are included. The references are arranged under the following headings, Reviews; Nets and quadrat samplers; Scoops, shovels and dredges; Grabs; Corers; Suction and air-lift samplers; Electroshocking samplers; Efficiencies and comparisons; and Samplers from catalogues. There is an index to samplers (by the common name) and an author index.

Zehaztasun handiko artikulazioen malgutasun analisia.

[EU]Azken urteetan argi geratu da gizakiak aurrera egiteko ezinbestekoa duela zehaztasuna. Teknologia berriak geroz eta bideratuagoak daude produktuen tamaina ahalik eta gehien murrizten edota produktu handien perdoiak nanometroetara hurbiltzeko ahaleginetan. Hau lortzeko bidean ezinbestekoa da elementu guztietan zehaztasuna limitera eramatea eta funtsean, honetan zentratuko da lan hau. Proiektu hau artikulazioen zehaztasuna hobetzeko tekniketan zentratuko da, gehiago zehaztuz, optika arloan lan egingo duen errobot baten artikulazioak analizatuko ditu. Artikulazioen zehaztasun optimoa lortzeko artikulazio hauek generazio berriko artikulazioak izatea pentsatu da, artikulazio flexible edo “flexible joints” izenekoak. Artikulazio hauek, orain artekoak ez bezala, ez dituzte bi elementu elkartuko, elementu bakarrez osatuta egongo dira eta bere buruarekiko errotazioz eta flexioz egingo dute lan honela, ohiko artikulazioek funtzionamendu egokirako behar duten lasaiera baztertu egingo da zehaztasun hobeak lortuz. Lan honetan zehar artikulazio flexible mota bat aukeratuko da eta geometriaren hainbat parametroren eta material ezberdinen aurrean edukiko duen jokaera analizatuko da. Aipatu beharra dago, artikulazio flexibleak azken hamarkadetan garatutako ideiak direnez beraiei buruzko informazioa oso pribatizatua dagoela eta ez dela lan erraza hau interneten edota liburutegietan topatzea. Ala ere, hauen analisirako aurkitu den informazio guztia eranskinetan dauden artikuluetan dago. Bertatik atera den informazio garrantzitsuena elementu finituen bitartezko analisian geometriak eduki beharreko baldintza batzuk eta ulermen eta aldaratze egokia lortzeko komeni diren datuak zehaztea izan da. Interesgarria da aipatzea analisiaren ondorioak konstante elastiko eta biratu dezaketen angelu maximoaren bitartez egin direla.

Surf oholeko gilen elementu finitu bidezko analisia.

[EU]Lan honetan, surf oholetan erabiltzen diren gila mota desberdinen analisia egin da. Horretarako, merkatuan garrantzi handiena duten bi enpresek euren katalogoetan eskaintzen dituzten modelo batzuk aztertu dira. Ingeniaritza simulazioak ahalbidetzen dituen ansys softwarea erabiliz egin da aukeratutako modeloen diseinu geometrikoa. Hauen analisiari ekin baino lehenago, gila hauetako bat aztertu da, hau osatzen duen materiala ezagutu eta ezaugarriak zehaztu asmoz. Aztertutakoa modelo guztiek erabiltzen duten ohiko materiala izanik, lortutako emaitzak baliogarriak dira gila guztiak aztertzeko. Materialaren propietateak ezagututa eta aipatutako softwareaz baliatuz, analisi estatikoa egin da. Horretarako, surfean aurkitzen diren ohiko egoera batzuk irudikatu dira, hauetan agertzen diren esfortzuak kalkulatuz. Gila bakoitzaren portaera, jasandako tentsio eta deformazioak aztertuz ondorioztatu da. Horrela, kasu bakoitzean komenigarrienak diren ezaugarriak oinarri hartuz, modelo desberdinen arteko konparaketa egin da.

Building TRACE (translations censored) theatre corpus: some methodological questions on text selection

Editores:Micaela Muñoz-Calvo; Carmen Buesa-Gómez

Letras, ideias e culturas políticas: os escritos de Nabuco de Araújo (1843-1876)

A presente tese foi elaborada a partir do legado documental de José Thomaz Nabuco de Araújo (1813-1878), constituído de textos impressos, manuscritos políticos, cartas e bilhetes produzidos especialmente nas décadas de cinquenta e sessenta do oitocentos e conservados no Instituto Histórico e Geográfico Brasileiro. Político e homem de letras, frequentou bibliotecas e livrarias daquelas décadas, quando teve contato com obras e tendências do pensamento europeu. Os livros da biblioteca da Faculdade de Direito de Recife, onde se formou bacharel juntamente com outros burocratas de sua geração em 1835, marcaram o início de práticas de leitura e escrita voltadas para a apropriação do conteúdo e construção intencional de ideias políticas expressas no decorrer de sua rica e complexa trajetória como senador e ministro da justiça em gabinetes de diferentes siglas partidárias. O personagem fez uso das linguagens e matrizes do pensamento jusnaturalista, utitilarista, liberal e do humanismo cívico ao protagonizar importantes debates diretamente relacionados à prática da cidadania no Segundo Reinado, com destaque para temas como emancipação dos escravos, a participação civil de estrangeiros no Brasil, a liberdade de imprensa, a descentralização, reformas eleitorais e a missão dos partidos políticos. Nesse sentido, a temporalidade das ideias presentes no discurso evidenciaram não só os aspectos perenes, como também transitórios do pensamento de Nabuco de Araújo. Certas transformações e permanências são perceptíveis no final da década de 1850, ocasião em que o Gabinete da Conciliação deixou de existir e deu passagem, já em 1862, à Liga Progressista, uma aliança entre conservadores moderados e antigos liberais do Império. O estudo sobre o processo de emancipação gradativa dos escravos, especialmente no ano de 1871, ocasião em que o político pertenceu ao Movimento Centro Liberal, também constitui oportunidade ímpar para verificar a introdução de termos como pessoa nos escritos do personagem. Guiado por seus próprios interesses, ou por interesses do Governo e do seu partido, Nabuco de Araújo contribuiu para a formulação de novos conceitos e práticas e, portanto, exerceu influência na configuração da cultura política imperial, junto a seus pares. O referencial teórico fundamentado em autores da História das Ideias, especialmente Quentin Skinner, e nos estudos de produção de texto de Robert Darnton possibilitaram o entendimento dos limites e intersecções entre o liberalismo e o conservadorismo político no Segundo Reinado, além de desencadear certo revisionismo histórico da obra Um Estadista do Império, biografia póstuma de José Thomaz Nabuco de Araújo, elaborada por seu filho Joaquim Nabuco.