Efeito do topiramato sobre o craving em usuários de crack

The study aims to analyze the effects of topiramato on the craving of crack users. It is an open crossover clinical trial involving users from the Psychosocial Care Center for Alcohol and Drugs (CAPSad) in city of Parnamirim, RN, approved by the CEP CAAE: 38710614.1.0000.5537, respecting the norms of the resolution n. 466/2012/CNS. The study produced preliminary two scientific papers: a theoretical essay and an integrative review, as a way of seeking the state of art. The first paper was based in the theoretical framework of Hinds, Chaves and Cypress, which focuses different contexts, from the issues of individual use to the coping policies in Brazil, highlighting that the situation and the complexity of the phenome requires coping strategies for the full attention to the user, family and society. As a result of the integrative review, among the 902 retrieved records, eight of them presented therapeutic schemes with positive effects for the craving of cocaine. They used nine different drugs. It is important to spot out that there was no result for the craving of crack. The data collection was conducted from December 2014 to July 2015 and has as sample predominantly single males. The sample was composed of 30 subjects who met the inclusion criteria: adults, age from 18 years, diagnosis of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) for cocaine/crack; cognitive capacity preserved; attendance to the service, participated at least three visits in the 12 months prior to data collection; and accepted to be monitored in the proposed treatment. Data was analyzed using descriptive statistics from the Statistical Package of Support for Social Sciences (SPSS) on the instruments: 1) Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST), pointing out, among other results, that only 14% used crack/cocaine weekly during treatment, while 83% used daily or weekly after the washout period; 2) Barratt Impulsiveness Scale, with an average of 80.23 and 77.47 with and without drug treatment, respectively. An analysis from the Student t test show no significant differences in impulsivity with or without the drug; and 3) Cocaine-Craving Questionnaire-Brief (CCK-B), indicating that the number of users with craving intensity level is significantly higher without drug treatment (86%) than with treatment (33%). The analysis between craving and level of impulsivity showed that there is a low correlation (Pearson) between these two variables during treatment and after the washout, demonstrating that impulsivity has low influence on the outcome of drug therapy. As conclusion, it was noted that the topiramate produces positive effect on reducing the craving for crack users and their use is a relevant strategy for efficacy in the treatment of crack users.

Efeito do topiramato sobre o craving em usuários de crack

The study aims to analyze the effects of topiramato on the craving of crack users. It is an open crossover clinical trial involving users from the Psychosocial Care Center for Alcohol and Drugs (CAPSad) in city of Parnamirim, RN, approved by the CEP CAAE: 38710614.1.0000.5537, respecting the norms of the resolution n. 466/2012/CNS. The study produced preliminary two scientific papers: a theoretical essay and an integrative review, as a way of seeking the state of art. The first paper was based in the theoretical framework of Hinds, Chaves and Cypress, which focuses different contexts, from the issues of individual use to the coping policies in Brazil, highlighting that the situation and the complexity of the phenome requires coping strategies for the full attention to the user, family and society. As a result of the integrative review, among the 902 retrieved records, eight of them presented therapeutic schemes with positive effects for the craving of cocaine. They used nine different drugs. It is important to spot out that there was no result for the craving of crack. The data collection was conducted from December 2014 to July 2015 and has as sample predominantly single males. The sample was composed of 30 subjects who met the inclusion criteria: adults, age from 18 years, diagnosis of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) for cocaine/crack; cognitive capacity preserved; attendance to the service, participated at least three visits in the 12 months prior to data collection; and accepted to be monitored in the proposed treatment. Data was analyzed using descriptive statistics from the Statistical Package of Support for Social Sciences (SPSS) on the instruments: 1) Alcohol, Smoking, and Substance Involvement Screening Test (ASSIST), pointing out, among other results, that only 14% used crack/cocaine weekly during treatment, while 83% used daily or weekly after the washout period; 2) Barratt Impulsiveness Scale, with an average of 80.23 and 77.47 with and without drug treatment, respectively. An analysis from the Student t test show no significant differences in impulsivity with or without the drug; and 3) Cocaine-Craving Questionnaire-Brief (CCK-B), indicating that the number of users with craving intensity level is significantly higher without drug treatment (86%) than with treatment (33%). The analysis between craving and level of impulsivity showed that there is a low correlation (Pearson) between these two variables during treatment and after the washout, demonstrating that impulsivity has low influence on the outcome of drug therapy. As conclusion, it was noted that the topiramate produces positive effect on reducing the craving for crack users and their use is a relevant strategy for efficacy in the treatment of crack users.

Vulnerabilidade externa e crescimento na economia brasileira : 1978/2000

Este artigo baseia-se em Resende, MFC e Teixeira, JR., “Competitividade, Vulnerabilidade Externa e Importações Totais e de Bens de Capital no Brasil: 1978/2000”, Seminário Interno da DISET. Aborda os aspectos da indústria de bens de capital brasileira, bem como a estimativa das funções de demanda de importação total e de bens de capital.

Principais características do consumo de duráveis no Brasil testes de separabilidade entre duráveis e não-duráveis

Estre trabalho investiga amplamente a evolução do consumo de bens duráveis no Brasil a partir da decisão de consumo individual e da possibilidade de existir restrição ao crédito. A contribuição mais relevante consiste na não rejeição da hipótese de separabilidade nas decisões de consumo de bens duráveis e não duráveis, já que tal hipótese é implicitamente utilizada por vários artigos que tratam a questão do consumo agregado no Brasil. Os resultados, aqui encontrados, sugerem que uma grande parcela dos consumidores está restrita ao crédito, existindo restrições de curto e longo prazo sobre a evolução do consumo de bens duráveis, não duráveis e renda.

Taxa de câmbio, rentabilidade e quantum exportado: existe alguma relação afinal? evidências para o Brasil

Este trabalho tem por objetivo avaliar em que medida a taxa de câmbio real é um condicionante importante para a evolução do quantum exportado brasileiro. Para tanto, é testada a existência de alguma relação entre variações na taxa de câmbio real e variações no quantum exportado, a saber, relação de causalidade no sentido de Granger em qualquer direção e correlação simultânea dos choques que afetam tais séries, conforme o método sugerido por Gourieroux e Jasiak (2001). Não foi possível obter evidência forte de relação entre a taxa de câmbio real e o quantum exportado em termos agregados para o período analisado (1977 a 2009). Entretanto, para várias desagregações e destinos foi possível detectar a existência de pelo menos uma destas relações entre a taxa de câmbio real e quantum exportado. Em particular, para o caso dos bens básicos, não há evidência de relação robusta entre as variáveis pesquisadas. O mesmo vale para bens intermediários. Já para os bens finais – bens de capital, de consumo de bens duráveis e não duráveis – a evidência de relação entre a taxa de câmbio e o quantum é mais forte. Como conclusão, o trabalho sugere que a taxa de câmbio, embora não tenha efeitos significativos em termos agregados, pode gerar importantes efeitos sobre a composição das exportações.

Do bom e do melhor: o consumo de bens de luxo por uma nova classe

A classe média brasileira apresentou um grande crescimento nos últimos anos representando 52% da população do país. Justamente devido a este fenômeno, surgiu o interesse nesta pesquisa que está focada em mulheres residentes no Rio de Janeiro. Podem ser observadas pesquisas recentes na área de marketing acerca dos hábitos de consumo desta classe, principalmente devido ao aumento do seu poder aquisitivo, porém pouco foram exploradas as particularidades dos diversos grupos dentro desta grande massa e de como se comportam em universos antes originários e característico das elites sociais, como o dos bens de luxo. A presente pesquisa tem o objetivo de contribuir para uma exploração mais detalhada acerca desta população. A fim de se observar a produção de conhecimento e o processo de construção de identidade das mulheres pesquisadas, o tema abordado foi o consumo de objetos de luxo. Três categorias se apresentam relevantes: Luxo, Luxo no Dia a Dia e Sonho de Consumo, que trazem informações distintas e complementares para melhor compreensão do grupo analisado. Apesar das teorias tradicionais de luxo apresentarem o status social, a diferenciação e o hedonismo como principais motivos do consumo destes objetos, outros aspectos relevantes foram observados quanto a este tipo de consumo, sendo a família a grande arena onde a maior parte das relações sociais e econômicas acontecem. A pesquisa também mostra o desenvolvimento de um olhar peculiar para a moda por parte do grupo estudado sendo a chave para o entendimento do que é luxo. Os resultados deste estudo mostram a riqueza das práticas e significados de consumo dentro de um mesmo grupo e a importância de um olhar qualitativo para que acadêmicos e gestores da área de marketing possam realmente entender os fenômenos de consumo das sociedades modernas, especialmente sociedades em pleno desenvolvimento social e econômico como o Brasil.

A Eficácia dos direitos fundamentais nos contratos civis e de consumo: uma teoria contratual baseada na colisão dos direitos ou bens constitucionalmente protegidos

The apparent virtuosity that if could wait of the globalization and the neoliberalism has given signals of deterioration in the contractual relations, especially in contracts of mass consumption, generating innumerable offensive situations to the basic rights and the goods constitutionally protected of the contractors. In the world of today, still that it does not reveal any desire, the individual practically is compelled to contract, for force of necessities and customs completely imposed, mainly in face of the essentiality of the services or agreed to goods. Ahead of as much and unexpected changes in the civil liames and of consumption, dictated for the globalization, it comes to surface the reflection if the private law e, more specifically, the civil law, meet prepared adequately to deal with these new parameters of the economy. The present dissertation has the intention to investigate if the globalization and the consequent neoliberalism, in this beginning of third millennium, will imply to revive of the principles and the basics paradigms of the contracts that consolidated and had kept, for more than two centuries, the liberal State. One notices that the study of this phenomenon it gains importance to the measure where if it aggravates the decline of the social State (Welfare State), with the embrittlement and the loss of the autonomy of the state authority, over all in countries of delayed modernity, as it is the case of Brazil, that presents deep deficiencies to give or to promote, with a minimum of quality and efficiency, essential considered public services to the collective and that if they find consecrated in the Federal Constitution, as basic rights or as goods constitutionally protecting, the example of the health, the education, the housing, the security, the providence, the insurance, the protection the maternity, the infancy and of aged and deficient. To the end, the incidence of constant basic rights of the man in the Constitution is concluded that, in the process of interpretation of the right contractual conflicts that have as object rights or goods constitutionally proteges, in the universe of the globalized perhaps economy and of the neoliberalismo, it consists in one of the few ways - unless the only one - that still they remain to over all deal with more adequately the contractual relations, exactly that if considers the presence of clauses generalities in the scope of the legislation infraconstitutional civil and of consumption, front the private detainers of social-economic power. To be able that it matters necessarily in disequilibrium between the parts, whose realignment depends on the effect and the graduation that if it intends to confer to the basic right in game in the private relation. The Constitution, when allowing the entailing of the basic rights in the privates relations, would be assuming contours of a statute basic of all the collective, giving protection to the man against the power, if public or independently private