Worldwide outdoor round robin study of organic photovoltaic devices and modules

Accurate characterization and reporting of organic photovoltaic (OPV) device performance remains one of the important challenges in the field. The large spread among the efficiencies of devices with the same structure reported by different groups is significantly caused by different procedures and equipment used during testing. The presented article addresses this issue by offering a new method of device testing using “suitcase sample” approach combined with outdoor testing that limits the diversity of the equipment, and a strict measurement protocol. A round robin outdoor characterization of roll-to-roll coated OPV cells and modules conducted among 46 laboratories worldwide is presented, where the samples and the testing equipment were integrated in a compact suitcase that served both as a sample transportation tool and as a holder and test equipment during testing. In addition, an internet based coordination was used via plasticphotovoltaics.org that allowed fast and efficient communication among participants and provided a controlled reporting format for the results that eased the analysis of the data. The reported deviations among the laboratories were limited to 5% when compared to the Si reference device integrated in the suitcase and were up to 8% when calculated using the local irradiance data. Therefore, this method offers a fast, cheap and efficient tool for sample sharing and testing that allows conducting outdoor measurements of OPV devices in a reproducible manner.

Ultraviolet exposure of melanoma cells induces fibroblast activation protein-α in fibroblasts: Implications for melanoma invasion.

Fibroblast activation protein-a (FAP-a) promotes tumor growth and cell invasiveness through extracellular matrix degradation. How ultraviolet radiation (UVR), the major risk factor for malignant melanoma, influences the expression of FAP-a is unknown. We examined the effect of UVR on FAP-a expression in melanocytes, keratinocytes and fibroblasts from the skin and in melanoma cells. UVR induces upregulation of FAP-a in fibroblasts, melanocytes and primary melanoma cells (PM) whereas keratinocytes and metastatic melanoma cells remained FAP-a negative. UVA and UVB stimulated FAP-a-driven migration and invasion in fibroblasts, melanocytes and PM. In co-culture systems UVR of melanocytes, PM and cells from regional metastases upregulated FAP-a in fibroblasts but only supernatants from non-irradiated PM were able to induce FAP-a in fibroblasts. Further, UV-radiated melanocytes and PM significantly increased FAP-a expression in fibroblasts through secretory crosstalk via Wnt5a, PDGF-BB and TGF-ß1. Moreover, UV radiated melanocytes and PM increased collagen I invasion and migration of fibroblasts. The FAP-a/DPPIV inhibitor Gly-ProP(OPh)2 significantly decreased this response implicating FAP-a/DPPIV as an important protein complex in cell migration and invasion. These experiments suggest a functional association between UVR and FAP-a expression in fibroblasts, melanocytes and melanoma cells implicating that UVR of malignant melanoma converts fibroblasts into FAP-a expressing and ECM degrading fibroblasts thus facilitating invasion and migration. The secretory crosstalk between melanoma and tumor surrounding fibroblasts is mediated via PDGF-BB, TGF-ß1 and Wnt5a and these factors should be evaluated as targets to reduce FAP-a activity and prevent early melanoma dissemination.

New susceptibility Loci associated with kidney disease in type 1 diabetes

Diabetic kidney disease, or diabetic nephropathy (DN), is a major complication of diabetes and the leading cause of end-stage renal disease (ESRD) that requires dialysis treatment or kidney transplantation. In addition to the decrease in the quality of life, DN accounts for a large proportion of the excess mortality associated with type 1 diabetes (T1D). Whereas the degree of glycemia plays a pivotal role in DN, a subset of individuals with poorly controlled T1D do not develop DN. Furthermore, strong familial aggregation supports genetic susceptibility to DN. However, the genes and the molecular mechanisms behind the disease remain poorly understood, and current therapeutic strategies rarely result in reversal of DN. In the GEnetics of Nephropathy: an International Effort (GENIE) consortium, we have undertaken a meta-analysis of genome-wide association studies (GWAS) of T1D DN comprising ~2.4 million single nucleotide polymorphisms (SNPs) imputed in 6,691 individuals. After additional genotyping of 41 top ranked SNPs representing 24 independent signals in 5,873 individuals, combined meta-analysis revealed association of two SNPs with ESRD: rs7583877 in the AFF3 gene (P?=?1.2×10(-8)) and an intergenic SNP on chromosome 15q26 between the genes RGMA and MCTP2, rs12437854 (P?=?2.0×10(-9)). Functional data suggest that AFF3 influences renal tubule fibrosis via the transforming growth factor-beta (TGF-ß1) pathway. The strongest association with DN as a primary phenotype was seen for an intronic SNP in the ERBB4 gene (rs7588550, P?=?2.1×10(-7)), a gene with type 2 diabetes DN differential expression and in the same intron as a variant with cis-eQTL expression of ERBB4. All these detected associations represent new signals in the pathogenesis of DN.

Absolute magnitudes and slope parameters for 250,000 asteroids observed by Pan-STARRS PS1 - preliminary results

We present the results of a Monte Carlo technique to calculate the absolute magnitudes (H) and slope parameters (G) of about 240,000 asteroids observed by the Pan-STARRS1 telescope during the first 15 months of its 3-year all-sky survey mission. The system's exquisite photometry with photometric errors asteroids rotation period, amplitude and color to derive the most-likely H and G, but its major advantage is in estimating realistic statistical+systematic uncertainties and errors on each parameter. The method was confirmed by comparison with the well-established and accurate results for about 500 asteroids provided by Pravec et al. (2012) and then applied to determining H and G for the Pan-STARRS1 asteroids using both the Muinonen et al. (2010) and Bowell et al. (1989) phase functions. Our results confirm the bias in MPC photometry discovered by ( Jurić et al., 2002).

Los nietos del trueno: Construcción social del espacio, parentesco y poder entre los Inkal-Awá

Los Awá -más conocidos por "los de afuera" como "Coaiqueres"- han surgido durante los últimos siglos a través de un proceso de etnogénesis y ocupan actualmente, en su gran mayoría (fuera de algunos asentamientos en el departamento del Putumayo), un territorio de aproximadamente 5.000 km/ que se encuentra en la Cordilera Occidental desde la estribaciones de la Sierra Nevada del Cumbal hasta cercanías de la Costa Pacifica. en el extremo suroccidental de Colombia y en el noroccidente del Ecuador. En los últimos años este grupo ha empezado a reunirse en torno a dos organizaciones regionales: la UNIPA (Unidad Indígena del Pueblo Awá), creada hace escasos tres años en Colombia y la FCA (Federación de Centros Awá) en el Ecuador con una trayectoria un poco más larga de aproximadamente ocho años. El Pueblo Awá está viviendo un momento importante en su historia: está pasando de una organización política descentralizada a una estructura con características de poder centralizado (con autori-dades institucionalizadas: gobernadores, presidentes y comisarios, entre otros). Es entonces importante, elegir como tema de estudio este cambio socio-politico a nivel de todo el grupo, o por los menos en lo que se refiere a Colombia, ya que para el caso de los Awá del Ecuador existe una valiosa investigación al respecto (cfr. Figueroa l99l). No obstante, el presente trabajo es un estudio de caso que describe la historia de un asentamiento Awá en el departamento de Nariño (Colombia); investiga la relación enrre la tradición y la modernidad en una comunidad particular: kankapi

Management Driven Hybrid Multicast Framework for Content Aware Networks

The need for better adaptation of networks to transported flows has led to research on new approaches such as content aware networks and network aware applications. In parallel, recent developments of multimedia and content oriented services and applications such as IPTV, video streaming, video on demand, and Internet TV reinforced interest in multicast technologies. IP multicast has not been widely deployed due to interdomain and QoS support problems; therefore, alternative solutions have been investigated. This article proposes a management driven hybrid multicast solution that is multi-domain and media oriented, and combines overlay multicast, IP multicast, and P2P. The architecture is developed in a content aware network and network aware application environment, based on light network virtualization. The multicast trees can be seen as parallel virtual content aware networks, spanning a single or multiple IP domains, customized to the type of content to be transported while fulfilling the quality of service requirements of the service provider.

Revue internationale des assurances : doctrine, droit, jurisprudence, science / publiée sous la direction de M. Eugène Baumgartner

1898/01 (T2,FASC1)-1898/02.

Revue internationale des assurances : doctrine, droit, jurisprudence, science / publiée sous la direction de M. Eugène Baumgartner

Périodicité : ; Trimestriel

Revue internationale des assurances : doctrine, droit, jurisprudence, science / publiée sous la direction de M. Eugène Baumgartner

1897/01 (FASC1,T1,N1)-1897/12 (FASC1,T1,N4).

La discrimination sur le marché du travail italien. Une comparaison des différentes méthodes d'estimation.

Rapport de recherche

Contributions dans l'analyse des modèles vectoriels de séries chronologiques saisonnières et périodiques

Thèse numérisée par la Division de la gestion de documents et des archives de l'Université de Montréal

??ngel Ferrant y la Escuela de Artes y Oficios de Viena

Resumen tomado de la publicaci??n

La Psicolog??a Criminal en la Polic??a de Franco

Resumen tomado de la publicaci??n

Inclusive Education, Person-Centered Planning & Systems Change Challenging Permutations and Opportunities

Resumen basado en el de la publicaci??n