821 resultados para Design strategies
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Esta tesis doctoral, bajo el título “La transformación de la fachada en la arquitectura del siglo XX. Evolución de los elementos arquitectónicos hacia el espacio único”, examina –siguiendo el método deductivo mediante investigación documental y de campo– los principales mecanismos proyectuales que han originado una transformación arquitectónica en la fachada. El término fachada, leído normalmente como sinónimo de arquitectura, ha sido analizado bajo taxonomías historiográficas, sociopolíticas, formales, compositivas o materiales. Más allá de estas clasificaciones, esta investigación determina cómo han evolucionado los elementos arquitectónicos hacia el espacio único, transformando con ello tanto la realidad física como el concepto de fachada. Proyectar, como diría Robert Venturi1. 1966, tanto desde el exterior al interior como desde el interior al exterior, produce las tensiones necesarias que ayudan a generar la arquitectura. De ahí la importancia del estudio de la transformación de la fachada como faccia, máscara, disfraz o sistema de representación, a la fachada como un diafragma activo, como un espacio de relación o como un límite donde se produce una experiencia arquitectónica con nuevos significados. El término fachada, del latín facies y del italiano facciata, fue creado como tal durante el siglo XVI, aunque como elemento arquitectónico es una realidad clásica y un concepto humanista reinventado en el Renacimiento. A principios del siglo XX la fachada se transforma radicalmente, con la aparición del vidrio plano de grandes dimensiones, y se despoja de su carga historicista. La transparencia literal hace desaparecer (negar) la fachada. La fachada se construye con nuevos materiales, nuevas tecnologías, y responde a un espacio global que espera a ser colonizado por una sociedad en constante mutación; un espacio que irá siendo cada vez más complejo a lo largo del siglo pasado y que tendrá como una de sus principales consecuencias un mayor grado de abstracción en la fachada. Para desarrollar con mayor precisión las intenciones de este trabajo se analiza la acepción de fachada en la que se encuadra la línea de investigación de la tesis doctoral. Siguiendo las indicaciones del Profesor Kenneth Frampton, se ha optado por dedicar precisamente a este análisis el primer capítulo, de precedentes, con el fin de hacer una relectura de la fachada barroca en clave contemporánea. La fachada barroca se estudia como un punto de inflexión, y origen de la transformación, frente al clasicismo de siglos precedentes. Se plantea por tanto como el primero de los mecanismos proyectuales motivo de estudio. Estos mecanismos han sido sometidos a una clasificación que responde a diversos tipos de espacio arquitectónico que han provocado la transformación de la fachada, analizando cada uno de ellos con un filtro bajo el cual se ha desarrollado un estudio pormenorizado. De esta manera se examinan la transformación compositiva de la fachada por medio del espacio dinámico (capítulo 00_precedentes) en San Carlo alle Quattro Fontane de Francesco Borromini, la transformación constructiva de la fachada por medio del espacio membrana (capítulo 01) en la Villa Tugendhat de Mies van der Rohe, la transformación diagramática de la fachada por medio del espacio pliegue (capítulo 02) en la terminal portuaria de Yokohama de FOA, la transformación tecnológica de la fachada por medio del espacio estructura (capítulo 03) en la mediateca de Sendai de Toyo Ito y, finalmente, la transformación fenomenológica de la fachada por medio del espacio múltiple (capítulo 04) en el pabellón de vidrio del Museo Toledo de SANAA. La investigación se completa con el análisis de una serie de textos que acompañan a cada uno de los capítulos, generando así un cuerpo de conocimiento global junto al análisis documental y las visitas de campo de cada uno de los casos de estudio considerados. ABSTRACT This doctoral thesis entitled “The Transformation of the Façade in Twentieth Century Architecture. The Evolution of Architectural Elements Towards a Single Space“ employs a deductive methodology incorporating both archival and field research, to examine the main design strategies that have given rise to the architectural transformation of the façade. The term façade, usually read as a synonym for architecture, has been analyzed under historiographic, sociopolitical, formal, compositive and material taxonomies. Far beyond these classifications, this study determines how architectural elements have evolved towards a single space, consequently transforming both the physical reality and the concept of façade. As Robert Venturi would say,1 to design from the inside-out and from the outside-in can create valid tensions that help generate architecture, hence the importance of this study of the transformation of the façade as a faccia, a mask, disguise or representation system, to the façade as an active diaphragm, a connective space or a limit within which architectural events with new meaning take place. The term fachada (Spanish for façade), from the Latin facies and the Italian facciata, appeared as such during the sixteenth century, although as an architectural element it is a classical ingredient and a humanist concept reinvented during the Renaissance. At the beginning of the 20th century, the façade is radically transformed with the introduction of large format plate glass, stripping it of its historicist content. Literal transparency causes the façade to disappear. The façade is built with new materials, new technologies, responding to a global space to be occupied by an everchanging society. It is a space that becomes increasingly more complex throughout the last century and which will have, as a consequence, a larger degree of abstraction in the façade. In order to more precisely focus this investigation, the meaning of the façade has been scrutinized. Following Professor Kenneth Frampton’s advice, the first chapter -Precedents- is precisely dedicated to this analysis, in order to understand the baroque façade read in a contemporary manner. The baroque façade has been studied as a turning point, the origin of the transformation of the façade, as compared to the classicism of previous centuries. For this reason it is considered the first design strategy to be studied. These strategeies have been sorted into a classification of architectural spaces that have caused the transformation of the façade, all of which having been analyzed using a methodology allowing for detailed study. Thus, this investigation examines the compositional transformation of the façade by means of a dynamic space (chapter 00: Precedents) in San Carlo alle Quattro Fontane by Francesco Borromini, the constructive transformation of the façade by means of a membrane space (chapter 01) in the Tugendhat Villa by Mies van der Rohe, the diagrammatic transformation of the façade by means of a folded space (chapter 02) in the Yokohama International Port Terminal by FOA, the technological transformation of the façade by means of a structure space (chapter 03) in the Sendai Mediathèque by Toyo Ito, and finally, the technological transformation of the façade by means of multiple space (chapter 04) in the Glass Pavilion of the Toledo Museum of Art by SANAA. The research is supplemented by the analysis of a series of texts presented alongside each chapter; creating a global body of knowledge together alongside the documentary analysis and on site analysis of each of the case studies considered.
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Support for molecular biology researchers has been limited to traditional library resources and services in most academic health sciences libraries. The University of Washington Health Sciences Libraries have been providing specialized services to this user community since 1995. The library recruited a Ph.D. biologist to assess the molecular biological information needs of researchers and design strategies to enhance library resources and services. A survey of laboratory research groups identified areas of greatest need and led to the development of a three-pronged program: consultation, education, and resource development. Outcomes of this program include bioinformatics consultation services, library-based and graduate level courses, networking of sequence analysis tools, and a biological research Web site. Bioinformatics clients are drawn from diverse departments and include clinical researchers in need of tools that are not readily available outside of basic sciences laboratories. Evaluation and usage statistics indicate that researchers, regardless of departmental affiliation or position, require support to access molecular biology and genetics resources. Centralizing such services in the library is a natural synergy of interests and enhances the provision of traditional library resources. Successful implementation of a library-based bioinformatics program requires both subject-specific and library and information technology expertise.
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Thesis (Master's)--University of Washington, 2016-06
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Users of safety-critical systems are expected to effectively control or monitor complex systems, with errors potentially leading to catastrophe. For such systems, safety is of paramount importance and must be designed into the human-machine interface. While many case studies show how inadequate design practice led to poor safety and usability, concrete guidance on good design practices is scarce. The paper argues that the pattern language paradigm, widely used in the software design community, is a suitable means of documenting appropriate design strategies. We discuss how typical usability-related properties (e.g., flexibility) need some adjustment to be used for assessing safety-critical systems, and document a pattern language, based on corresponding "safety-usability" principles
Improving T cell-induced response to subunit vaccines:opportunities for a proteomic systems approach
Resumo:
Prophylactic vaccines are an effective strategy to prevent development of many infectious diseases. With new and re-emerging infections posing increasing risks to food stocks and the health of the population in general, there is a need to improve the rationale of vaccine development. One key challenge lies in development of an effective T cell-induced response to subunit vaccines at specific sites and in different populations. Objectives: In this review, we consider how a proteomic systems-based approach can be used to identify putative novel vaccine targets, may be adopted to characterise subunit vaccines and adjuvants fully. Key findings: Despite the extensive potential for proteomics to aid our understanding of subunit vaccine nature, little work has been reported on identifying MHC 1-binding peptides for subunit vaccines generating T cell responses in the literature to date. Summary: In combination with predictive and structural biology approaches to mapping antigen presentation, proteomics offers a powerful and as yet un-tapped addition to the armoury of vaccine discovery to predict T-cell subset responses and improve vaccine design strategies.
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PURPOSE: To assess the performance of four commercially available silicone hydrogel multifocal monthly contact lens designs against monovision. METHODS: A double-masked randomized crossover trial of Air Optix Aqua multifocal, PureVision 2 for Presbyopia, Acuvue OASYS for Presbyopia, Biofinity multifocal, and monovision with Biofinity contact lenses was conducted on 35 presbyopes (54.3 ± 6.2 years). After 4 weeks of wear, visual performance was quantified by high- and low-contrast visual acuity under photopic and mesopic conditions, reading speed, defocus curves, stereopsis, halometry, aberrometry, Near Activity Visual Questionnaire rating, and subjective quality of vision scoring. Bulbar, limbal, and palpebral hyperemia and corneal staining were graded to monitor the impact of each contact lens on ocular physiology. RESULTS: High-contrast photopic visual acuity (p = 0.102), reading speed (F = 1.082, p = 0.368), and aberrometry (F = 0.855, p = 0.493) were not significantly different between presbyopic lens options. Defocus curve profiles (p <0.001), stereopsis (p <0.001), halometry (F = 4.101, p = 0.004), Near Activity Visual Questionnaire (F = 3.730, p = 0.007), quality of vision (p = 0.002), bulbar hyperemia (p = 0.020), and palpebral hyperemia (p = 0.012) differed significantly between lens types, with the Biofinity multifocal lens design principal (center-distance lens was fitted to the dominant eye and a center-near lens to the nondominant eye) typically outperforming the other lenses. CONCLUSIONS: Although ocular aberration variation between individuals largely masks the differences in optics between current multifocal contact lens designs, certain design strategies can outperform monovision, even in early presbyopes.
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The purpose of this study was to identify the factors that motivate nursing faculty to use service learning. The study was based on the theory of planned behavior (TPB), which implies that the target behavior of intention to use service learning in higher education is influenced by the predictor variables of behavior beliefs (attitude), normative beliefs (peer influence), and control beliefs (confidence and resources). External variables were also considered (years of teaching experience, tenure status, and the type of curriculum). ^ Group interviews and a pilot test were conducted to create the instrument for the study, and Cronbach alpha were calculated for survey item reliability. The participants were full time undergraduate nursing faculty members ( n = 160) in the Southeastern United States who taught in universities with accredited nurse education programs. Demographic data as well as scores on scaled survey responses were used to evaluate the intention of nursing faculty to use service learning in their classes. ^ Pearson product moment correlation coefficient and path analysis were applied to the data. The correlation findings indicated that there were statistically significant relationships between behavior beliefs, normative beliefs, and control beliefs and nursing faculty intention to use service learning. The path analysis also indicated that behavior beliefs and normative beliefs were significant, while control beliefs were not a strong influence on intention to use service learning. Normative beliefs showed the strongest direct influence. The use of a community based curriculum also had a positive influence on intention, and faculty with tenure status were more likely to have positive behavior beliefs (attitude) towards service learning. Finally, as teaching experience increased, positive attitudes towards the intention to use service learning decreased. Seventy-nine percent of the variation in the intention to use service learning was explained by the theory of planned behavior, the type of curriculum, teaching experience, and tenure status. These results will assist nursing administration and faculty to design strategies to facilitate the implementation of service learning pedagogy, as well as a community based curriculum which will help meet the 21st century goals set forth from the American Association of Colleges of Nursing. ^
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The purpose of this study was to identify the factors that motivate nursing faculty to use service learning. The study was based on the theory of planned behavior (TPB), which implies that the target behavior of intention to use service learning in higher education is influenced by the predictor variables of behavior beliefs (attitude), normative beliefs (peer influence), and control beliefs (confidence and resources). External variables were also considered (years of teaching experience, tenure status, and the type of curriculum). Group interviews and a pilot test were conducted to create the instrument for the study, and Cronbach alpha were calculated for survey item reliability. The participants were full time undergraduate nursing faculty members (n=-160) in the Southeastern United States who taught in universities with accredited nurse education programs. Demographic data as well as scores on scaled survey responses were used to evaluate the intention of nursing faculty to use service learning in their classes. Pearson product moment correlation coefficient and path analysis were applied to the data. The correlation findings indicated that there were statistically significant relationships between behavior beliefs, normative beliefs, and control beliefs and nursing faculty intention to use service learning. The path analysis also indicated that behavior beliefs and normative beliefs were significant, while control beliefs were not a strong influence on intention to use service learning. Normative beliefs showed the strongest direct influence. The use of a community based curriculum also had a positive influence on intention, and faculty with tenure status were more likely to have positive behavior beliefs (attitude) towards service learning. Finally, as teaching experience increased, positive attitudes towards the intention to use service learning decreased. Seventy-nine percent of the variation in the intention to use service learning was explained by the theory of planned behavior, the type of curriculum, teaching experience, and tenure status. These results will assist nursing administration and faculty to design strategies to facilitate the implementation of service learning pedagogy, as well as a community based curriculum which will help meet the 21st century goals set forth from the American Association of Colleges of Nursing.
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This study analyzes transitional areas between public and private space in order to develop a design that might improve social interaction in the city. Architectural elements in specific pedestrian friendly spaces within the Miami area were identified and analyzed as social spaces in terms developed by Ali Mandanipour. Proximity, visual permeability, intersection, layering, and monumentality are design strategies used in many projects to enhance individual encounters. These strategies typically apply to transitional areas and serve as the direct physical links perceived by individuals moving between public and private areas. This project explores the different approaches to transitional areas in the design of an art gallery and surrounding artists' studios on Lincoln Road.
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Historic landscapes are vital elements of our nation's cultural continuum and must be protected as a part of living fabric of the community. This thesis addressed the preservation of historic landscape gardens, focusing on design strategies that can make historic time legible in landscape. It proposed a landscape plan for the preservation of Palm Cottage Garden in Gotha, Florida, a significant historic landscape resource. To determine the criteria used to establish how and to what period the estate should be restored, the Secretary of the Interior's Guidelines for the Treatment of Cultural Landscapes was followed. This process involved documenting the current site conditions and evaluating natural and cultural resources. For the garden to continue to keep its historic fabric, rehabilitation was selected. The garden was designed to preserve existing features and make efficient contemporary use of the garden possible. The landscape plan focused on strategies that reveal the site's significant past through new design elements while adapting to current and future needs.
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The nursing staff is now the largest contingent of professionals in healthcare environments, with more than 1.8 million professionals, and of these 15% are men, showing a masculinization of the historical profession and culturally conceived and carried out by women (COFEN / FIOCRUZ, 2013). This dissertation discusses the profession forward to some issues related to gender, quality of life and night work. Objective: To analyze the impact that shift work has the professional quality of life male, through a specific instrument to identify the main problems and joint damage to that front group to his professional activity. Methods: descriptivo, Cross-sectional study with a quantitative approach, performed with 72 professional male nursing staff, 41 (56.9%) nursing technicians, 18 (25%) of nursing assistants and 13 (18.1%) of nurses, in January 2015 in a university hospital in the city of Uberlândia (Minas Gerais). For this, we used the WHOQOL-BREF questionnaire. Quantitative variables were described as mean, standard deviation, maximum and minimum, in addition to the Shapiro-Wilk test and Kruskal-Wallis used in the data analysis, with a confidence level of 5% (p <0.05). Results: the profile of respondents, most are married 42 (58.3%) under the employment contract via Single Legal Regime 50 (69.4%) with mean age of 40 and having 16 years of service; and within a range of 0 to 100, the areas with better evaluation were the Social Relations (70.1) and psychological (67.5); already the worst were the Environment (57.4) and Physical (65.4). In the overall assessment, the average was 63.3 and staying below the national average (65-70). Thus, the professionals who were married obtained better scores, regardless of the category which is in the nursing team. Conclusions: The group is average, taking into account the standard deviation, but we can say that working conditions affect their profession, and these results allow the detection of the difficulties experienced by men of the nursing team, and can cooperate with the design strategies that benefit or minimize the search for conflicts that affect the health of these workers and their quality of life.
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Advancements in retinal imaging technologies have drastically improved the quality of eye care in the past couple decades. Scanning laser ophthalmoscopy (SLO) and optical coherence tomography (OCT) are two examples of critical imaging modalities for the diagnosis of retinal pathologies. However current-generation SLO and OCT systems have limitations in diagnostic capability due to the following factors: the use of bulky tabletop systems, monochromatic imaging, and resolution degradation due to ocular aberrations and diffraction.
Bulky tabletop SLO and OCT systems are incapable of imaging patients that are supine, under anesthesia, or otherwise unable to maintain the required posture and fixation. Monochromatic SLO and OCT imaging prevents the identification of various color-specific diagnostic markers visible with color fundus photography like those of neovascular age-related macular degeneration. Resolution degradation due to ocular aberrations and diffraction has prevented the imaging of photoreceptors close to the fovea without the use of adaptive optics (AO), which require bulky and expensive components that limit the potential for widespread clinical use.
In this dissertation, techniques for extending the diagnostic capability of SLO and OCT systems are developed. These techniques include design strategies for miniaturizing and combining SLO and OCT to permit multi-modal, lightweight handheld probes to extend high quality retinal imaging to pediatric eye care. In addition, a method for extending true color retinal imaging to SLO to enable high-contrast, depth-resolved, high-fidelity color fundus imaging is demonstrated using a supercontinuum light source. Finally, the development and combination of SLO with a super-resolution confocal microscopy technique known as optical photon reassignment (OPRA) is demonstrated to enable high-resolution imaging of retinal photoreceptors without the use of adaptive optics.
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Design for behaviour change aims to influence user behaviour, through design, for social or environmental benefit. Understanding and modelling human behaviour has thus come within the scope of designers’work, as in interaction design, service design and user experience design more generally. Diverse approaches to how to model users when seeking to influence behaviour can result in many possible strategies, but a major challenge for the field is matching appropriate design strategies to particular behaviours (Zachrisson & Boks, 2012). In this paper, we introduce and explore behavioural heuristics as a way of framing problem-solution pairs (Dorst & Cross, 2001) in terms of simple rules. These act as a ‘common language’ between insights from user research and design principles and techniques, and draw on ideas from human factors, behavioural economics, and decision research. We introduce the process via a case study on interaction with office heating systems, based on interviews with 16 people. This is followed by worked examples in the ‘other direction’, based on a workshop held at the Interaction ’12 conference, extracting heuristics from existing systems designed to influence user behaviour, to illustrate both ends of a possible design process using heuristics.
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A Cultura Digital é uma realidade do século XXI, onde as relações humanas são fortemente mediadas pelas tecnologias e pelo digital. O Digital tem mudado o comportamento das pessoas e influenciado o seu meio cultural. O conceito de Cultura digital inclui saber onde encontrar informação, ferramentas e sistemas, necessários para cumprir uma determinada tarefa de forma não só eficaz, mas também mais eficiente. As competências para explorar as tecnologias que o permitam, são cada vez mais exigidas na interação em sociedade. Tendo em consideração estudos existentes associados com as competências TIC, nomeadamente os propostos pela UNESCO e pelo Executivo Angolano no seu Plano Nacional de Desenvolvimento para 2013-2017, em que está enquadrada a iniciativa da Rede de Mediatecas de Angola, foi tomada a Cultural Digital e a sua promoção no ambito das Mediatecas. Numa primeira avaliação desde da abertura da Mediateca em Fevereiro de 2014, verificamos uma fraca adesão dos professores na utilização dos serviços da Mediateca do Huambo – Angola. Coloca-se neste contexto a questão do porquê que é que os professores não exploram as TIC para as atividades docentes ou da sua aprendizagem? Desta forma, é considerada a questão de investigação: Quais as estratégias a desenvolver para incrementar a exploração das TIC pelos professores e como a Mediateca do Huambo pode servir de espaço para a promoção da Cultura Digital. Foi realizado um estudo de caso, no contexto da Mediateca do Huambo, em que foi efetuada uma recolha de dados pela (a) aplicação de questionários aos professores do 1º e 2º Ciclo do Ensino Secundário do Município do Huambo para mapear as competências TIC dos professores segundo os padrões da UNESCO e o apuramento da formação e uso das TIC em contexto educativo, (b) pela aplicação de um conjunto de tarefas com o objetivo de verificar quais as competências digitais dos professores e por último (c), a implementação do projeto-piloto denominado “ Mediateca +Escola” com o objetivo de levar à Mediateca professores e alunos para desenvolver um projeto TIC onde os professores teriam uma oportunidade de demostrar as competências que afirmavam possuir. Como resultado final obtido neste estudo de caso podemos concluir que 71,27% indicanos que os professores têm a perceção que necessitam de mais formação e desenvolvimento de competências TIC, 27,50% confirma que os professores creem que têm confiança nas TIC. Em face das respostas com valores negativos que apontam para a necessidade de delinear estratégia para capacitar este grupo em competências TIC de forma a incluí-los na sociedade em rede providos de uma Cultura Digital foi proposto o modelo que permite validar os dados obtidos pelo questionário permitindo também delinear estratégias com vista à promoção da Cultura Digital.
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A história da sociedade humana sempre foi fiel ao retrato das diferentes etapas do seu desenvolvimento. O ser humano sempre sentiu a necessidade de realizar os seus propósitos de sobrevivência, conjugando os diferentes elementos inerentes a este processo. As organizações se destacam na manipulação de recursos valiosos, que exigem a busca permanente de equilíbrios sustentáveis. Para tal, estas elaboram estratégias, que permitam o alcance de seus objetivos, garantindo a sustentabilidade interna e externa. O presente trabalho de pesquisa centrou o seu exercício na perceção do papel que a Área de Recursos Humanos no processo definição da estratégia, focalizando os diferentes modelos que vão desde o RH estritamente operacional ao RH estratégico. Esta dimensão evidenciou o papel decisivo do alinhamento do RH à estratégia, como parte integrante da estratégia global da organização, desde a formulação até a implementação. Foi realizado um estudo de caso qualitativo na Empresa Nacional de Exploração de Aeroportos e Navegação Aérea (ENANA-EP), em Angola, caracterizado, pela recolha exaustiva de documentos relevantes da gestão da empresa, e concomitantemente a coleta de dados por via de um questionário escrito, que revelaram o estádio evolutivo da Área de RH, bem como o seu posicionamento ainda como órgão de consultoria interna, necessitando trabalhar novas ideias e estruturar procedimentos que integrem com maior facilidade a Área de RH no processo de definição da estratégia, configurando-a como gestora de talentos e competências, com foco no conhecimento e no capital humano.