Manuel théorique et pratique du fabricant de cidre et de poiré, avec les moyes [i.e. moyens] d'imiter avec le suc des pommes ou des poires, le vin de raisin, l'eau-de-vie et le vinaigre de vin.

Mode of access: Internet.

Les Bachanales; ou, Loix de Bachvs, prince de Nise en Arabie, roy d'Egypte et des Indes, et dieu des bevvevrs. Ouvrage lirosophique, dans lequel on void les diuers & merueilleux effects du vin, les extrauagantes & ridicules faillies où il porte l'homme, par les excez & le mauuais vsage de cette precieuse & charmante boisson; bref, tout ce que peut produire la fumée d'vn long & libre repas, ensemble l'eloge du tabac.

Eloge dv tabac ... p. 56-62.

Les femmes, le vin et le tabac; vaudeville en un acte,

"Représenté pour la première fois, sur le theâtre des Folies Dramatiques, le 31 décembre, 1836".

Examen chymique de différentes substances minérales; : essais sur le vin, les pierres, les bézoards, & d'autres parties d'histoire naturelle & de chymie;. Traduction d'une lettre de M. Lehmann, sur la mine de plomb rouge.. /

Includes index.

Traité théorique et pratique sur la culture de la vigne : avec l'art de faire le vin, les eaux-de-vie, esprit-de-vin, vinaigres simples et composés /

Mode of access: Internet.

Traitez des Cloches, et de la Sainteté de l'offrande du Pain et du Vin aux Messes des Morts, non confondu avec le pain & le Vin qu'on offroit sur les Tombeaux.

Bound in full contemporary calf with title in gilt on spine.

Histoire du bon vin /

"Cet ouvrage a été publié dès le mois de Janvier 1896 dans l'Acclimatation, la Revue de Viticulture et autres journaux par articles revus et corrigés"--P. [155]

La vigne et le vin dans l'antiquité égyptienne

Mode of access: Internet.

Étude sur le ver du bouchon ou moulon du vin.

Mode of access: Internet.

La vigne et le vin chez les Romains,

Mode of access: Internet.

Effet du climat viticole sur la perception sensorielle du vin: éléments méthodologiques pour une modélisation au niveau mondial.

Summary The objective of this study was to develop a methodology capable of modeling the effect of viticultural climate on wine sensory characteristics. The climate was defined by the Géoviticulture Multicriteria Climatic Classification System (Tonietto and Carbonneau, 2004), based on the Heliothermal index (HI), Cool Night index (CI) and Dryness index (DI). The sensory wine description was made according with the methodology established by Zanus and Tonietto (2007). In this study we focused on the 5 principal wine producing regions of Brazil: Serra Gaúcha, Serra do Sudeste, Campanha (Meridional and Central), Planalto Catarinense and Vale do Submédio São Francisco. The results from Principal Component Analysis (PCA) show the HI and CI opposed to the DI. High HI values were associated to a lower perception of acidity, as well as to a lower perception of concentration (palate) and persistence by mouth. For the red wines, high HI values were positively associated with alcohol (palate), conversely to the DI index, which showed high values related to the perception of tanins and acidity. The higher the CI, the lower were the color intensity, tanins, concentration and persistence by mouth. It may be concluded that viticultural climate - expressed by the HI, CI and DI indexes ? adequately explained much of the sensory differences of the wines made in different regions. The methodology proposed and the enlargement of the database it will maybe open the possibility of modeling the part of wine sensory characteristics as dependent variables of the viticultural climate, as defined by the Géoviticulture MCC System. Keywords: viticultural climate, modeling, wine, tipicity.

WINE GRAPE QUALITY OF GRAPEVINES GROWN IN THE CERRADO ECOREGION OF BRAZIL

Aims: Geographical indication plays an important role in the improvement of wine quality. In this context, the search for new grape growing areas has been constant. The Sao Francisco River Valley in the cerrado of Minas Gerais State (Brazil) has been pointed out in the Geoviticulture Multicriteria Climatic Classification System (MCC System) as a potentially winegrowing region, especially considering the autumn-winter period when night temperatures are favorable to grape ripening. In this work, we studied the maturation curves and fruit composition of four wine grape varieties (Syrah, Merlot, Cabernet-Sauvignon and Cabernet Franc) in two growing seasons in order to validate the state of Minas Gerais as a new winegrowing region in Brazil. Methods and results: Quality parameters (berry weight, pH, titratable acidity and total soluble solids) were measured weekly from veraison to harvest, and sugar, organic acid, anthocyanin and phenolic concentrations were determined in must and berry skins and seeds at harvest. Syrah berries showed the highest weight throughout maturation which contributed to higher yield (8.92 ton ha(-1)), followed closely by Merlot (8.07 ton ha(-1)). Bern, sugar concentrations were higher and malic acid levels were lower than the values usually observed in wine grapes harvested during summer in traditional winegrowing regions in Brazil. Cabernet Franc showed lower levels of anthocyanins and skin phenolics per kg berries and the highest values of seed phenolics, which were not affected by growing season. Conclusion: Weather conditions of the cerrado of Minas Gerais State in Brazil during winter allowed complete maturation of Cabernet-Sauvignon, Cabernet Franc, Merlot and Syrah cultivars as revealed by the satisfactory sugar, anthocyanin and skin phenolic accumulation. Significance and impact of the study: This study revealed the potential of the cerrado ecoregion in the northeast of Minas Gerais to become a new winemaking region in Brazil.

Multi-system neurological disease is common in patients with OPA1 mutations

Additional neurological features have recently been described in seven families transmitting pathogenic mutations in OPA1, the most common cause of autosomal dominant optic atrophy. However, the frequency of these syndromal `dominant optic atrophy plus` variants and the extent of neurological involvement have not been established. In this large multi-centre study of 104 patients from 45 independent families, including 60 new cases, we show that extra-ocular neurological complications are common in OPA1 disease, and affect up to 20% of all mutational carriers. Bilateral sensorineural deafness beginning in late childhood and early adulthood was a prominent manifestation, followed by a combination of ataxia, myopathy, peripheral neuropathy and progressive external ophthalmoplegia from the third decade of life onwards. We also identified novel clinical presentations with spastic paraparesis mimicking hereditary spastic paraplegia, and a multiple sclerosis-like illness. In contrast to initial reports, multi-system neurological disease was associated with all mutational subtypes, although there was an increased risk with missense mutations [odds ratio = 3.06, 95% confidence interval = 1.44-6.49; P = 0.0027], and mutations located within the guanosine triphosphate-ase region (odds ratio = 2.29, 95% confidence interval = 1.08-4.82; P = 0.0271). Histochemical and molecular characterization of skeletal muscle biopsies revealed the presence of cytochrome c oxidase-deficient fibres and multiple mitochondrial DNA deletions in the majority of patients harbouring OPA1 mutations, even in those with isolated optic nerve involvement. However, the cytochrome c oxidase-deficient load was over four times higher in the dominant optic atrophy + group compared to the pure optic neuropathy group, implicating a causal role for these secondary mitochondrial DNA defects in disease pathophysiology. Individuals with dominant optic atrophy plus phenotypes also had significantly worse visual outcomes, and careful surveillance is therefore mandatory to optimize the detection and management of neurological disability in a group of patients who already have significant visual impairment.

Texto para discuss??o 45: a conceitua????o de governabilidade e governan??a, da sua rela????o entre si e com o conjunto da reforma do Estado e do seu aparelho

O objetivo do presente artigo ?? introduzir o leitor ??s principais abordagens feitas aos conceitos de governabilidade e governan??a dispon??veis na literatura nacional/internacional contempor??nea e buscar compreender o v??nculo din??mico destas categorias entre si e a sua articula????o com a tem??tica maior da reforma do Estado e do seu aparelho no Brasil

M??dulo 1- contextualiza????o: curso gest??o de projetos

Esse documento trata de: hist??ria do gerenciamento de projetos;fontes relevantes de conhecimento sobre gerenciamento de projetos; o que ?? projeto; o que ?? opera????o; diferen??as entre projetos e opera????es; gerenciamento de projetos; o que ?? um programa; o que ?? um portf??lio; relacionamento entre projeto, programa e portf??lio