999 resultados para 235-1
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Objetivou-se avaliar o manejo do solo na entrelinha da seringueira de forma mecânica com grade e roçadora e com cultura de cobertura sobre as propriedades físicas do solo. Para isto, implantou-se a seringueira (PB 235 e RRIM 701) em Latossolo Vermelho em Jaboticabal-SP, em 1992, de forma que a área da entrelinha da cultura foi manejada com gradagem, roçadora e cultura de cobertura kudzu-tropical (Pueraria phaseoloides). Após 8 anos de cultivo, foram analisados alguns atributos físicos do solo (densidade, macro, micro e porosidade total, granulometria e argila dispersa em água), na entrelinha da cultura. O manejo mecânico e o de culturas de cobertura na entrelinha da seringueira afetaram as propriedades físicas do solo, especialmente a porosidade e a densidade, entretanto não influenciaram significativamente a granulometria do solo. As maiores alterações físicas em função do manejo da entrelinha da seringueira manifestaram-se especialmente na camada superficial do solo (0-20 cm). O manejo com roçadora reduziu significativamente a porosidade do solo (0,08-0,04 m³/m³) e aumentou a sua densidade (1,4-1,5 kg/dm³), ao passo que o manejo com grade não degradou as propriedades físicas do solo, comparado com roçadora e a cultura de cobertura com kudzu tropical.
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We investigated kidney and lung alterations caused by intercellular adhesion molecule type 1 (ICAM-1) blockade after ischemia and reperfusion of hind limb skeletal muscles. Rats were submitted to ligature of the infrarenal aorta for 6 h. The animals were randomized into three groups of 6 rats each: group I, sacrificed after ischemia; group II, reperfusion for 24 h, and group III, reperfusion for 24 h after receiving monoclonal anti-ICAM-1 antibodies. At the end of the experiment, blood samples were collected for creatinine, lactate dehydrogenase, creatine phosphokinase, potassium, pH and leukocyte counts. Samples were taken from the muscles of the hind limbs and from the kidneys and lungs for histological analysis and measurement of the neutrophil infiltrate by myeloperoxidase staining. The groups did not differ significantly with regard to the laboratory tests. There were no major histological alterations in the kidneys. An intense neutrophil infiltrate in the lungs, similar in all groups, was detected. Myeloperoxidase determination showed that after reperfusion there was significantly less retention of polymorphonuclear neutrophils in the muscles (352 ± 70 vs 1451 ± 235 × 10² neutrophils/mg; P<0.01) and in the kidneys (526 ± 89 vs 852 ± 73 × 10² neutrophils/mg; P<0.01) of the animals that received anti-ICAM-1 before perfusion compared to the group that did not. The use of anti-ICAM-1 antibodies in this experimental model minimized neutrophil influx, thus reducing the inflammatory process, in the muscles and kidneys after ischemia and reperfusion of the hind limbs.
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Resumen tomado de la web del Departamento de Educación
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Resumen tomado de la web del Departamento de Educación
Merindades : materiales de historia de Navarra para la educación secundaria : 1, síntesis histórica.
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Resumen tomado de la web del Departamento de Educación
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Resumen tomado de la web del Departamento de Educación
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Resumen tomado de la web del Departamento de Educación
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This study reports the in vivo stimulatory effects of Cramoll 1,4 on rat spleen lymphocytes as evidenced by an increase in intracellular reactive oxygen species (ROS) production, Ca(2+) levels, and interleukin (IL)-1 beta expression. Cramoll 1,4 extracted from seeds of the Leguminosae Cratylia mollis Mart., is a lectin with antitumor and lymphocyte mitogenic activities. Animals (Nine-week-old male albino Wistar rats, Rattus norvegicus) were treated with intraperitoneal injection of Cramoll 1,4 (235 mu g ml(-1) single dose) and, 7 days later, spleen lymphocytes were isolated and analyzed for intracellular ROS, cytosolic Ca(2+), and IL-6, IL-10, and IL-1 mRNAs. Cell viability was investigated by annexin V-FITC and 7-amino-actinomycin D staining. The data showed that in lymphocytes activated by Cramoll 1,4 the increase in cytosolic and mitochondrial ROS was related to higher cytosolic Ca(2+) levels. Apoptosis and necrosis were not detected in statistically significant values and thus the lectin effector activities did not induce lymphocyte death. In vivo Cramoll 1,4 treatment led to a significant increase in IL-1 beta but IL-6 and -10 levels did not change. Cramoll 1,4 had modulator activities on spleen lymphocytes and stimulated the Th2 response.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)