Nutrient Enhanced Coastal Ocean Productivity (NECOP). Data report: CTD and hydrographic data, R/V Pelican cruise, April 3-11, 1993

The Nutrient Enhanced Coastal Ocean Productivity (NECOP) Program is a component of NOAA's Coastal Ocean Program. The central hypothesis of this research is: Anthropogenic nutrient inputs have enhanced coastal ocean productivity with subsequent impacts on coastal ocean water quality, living resource yields, and the global marine carbon cycle. The initial study area for this program is the Mississippi/Atchafalaya River Outflow and adjacent Louisiana shelf region.

The fisheries of Lake Wamala: a report on the fisheries resources surveys conducted during 1975/78 and 1988/92

Lake wamala was opened to commercial fishing in 1960. Interviews with the local fishermen during 1975/78 (Okaronon 1975, 1976, 1977, 1989) revealed that fishing for subsistence had been going on long before stocking was done. The subsistence fishing was conducted along rivers and at river mouths using basket traps (mainly made of papyrus stems), weirs and hooks and that the fish species caught were predominantly clarias (mudfish/male) and protopterus Lungfish/Mamba). These interviews did not, however, reveal the presence of tilapiine species in Lake wamala prior to stocking. These interviews did not however reveal the presence of tillapine species in lake wamala prior to stocking. Following the opening of the lake to commercial fishing in 1960, Lake Wamala provided a very profitable commercial fishery throughout the 1960s. However, during the early 1970s the fishermen started complaining of continued decline in catch rates from about 8 kg (15 fish) of O. niloticus per net per night if in 1966 to less than 1 kg per net per night by 1975.

Studies on geo-morphology, ecology and fish production of the 92 rivers of Rajshahi Division, Bangladesh

Geo-morphology, ecology and fish production of the 92 rivers of Rajshahi division have been presented in this paper. Fifteen rivers are dead and 11 rivers have severe erosion problem. Siltation has increased in 66 rivers and depth has decreased in 11 rivers. Sixty nine rivers are suffering from low flow conditions. Fish diversity has decreased in 20 rivers while fish production has declined in 75 rivers. A total of 31 fish species have extinct, 25 species are under threat of extinction and 43 species have low production. Siltation and pollution are the major causes of fish habitat loss. Recommendations are made to protect and conserve fish habitat and riverine fisheries of Rajshahi division.

Two-electron-one-photon M1 and E2 transitions between the states of the 2p(3) and 2s(2)2p odd configurations for B-like ions with 18 <= Z <= 92

Two-electron-one-photon (TEOP) M1 and E2 transition energies, line strengths and transition probabilities between the states of the 2p(3) and 2s(2)2p odd configurations for B-like ions with 18 <= Z <= 92 have been calculated using the GRASP2K package based on the multiconfiguration Dirac-Hartree-Fock (MCDHF) method. Employing active-space techniques to expand the configuration list, we have systematically considered the valence, core-valence and core-core electron correlation effects. Breit interaction and quantum electrodynamical (QED) effects were also included to correct atomic state wavefunctions and the corresponding energies. Influences of electron correlation, Breit interaction and QED effects on transition energies and line strengths of the TEOP M1 and E2 transitions were analysed in detail. The present results were also compared with other theoretical and experimental values.

Cys-92, Cys-95, and the C-terminal 12 residues of the Vibrio harveyi ferric uptake regulator (Fur) are functionally inessential

Ferric uptake regulator (Fur) is a global regulator involved in multiple aspects of bacterial life. The gene encoding the Vibrio harveyi Fur (Fur(vh)) was cloned from a pathogenic V. harveyi strain isolated from diseased fish. Furvh shares 77% overall sequence identity with the Escherichia coli Fur (Fur(Ec)) and could complement a mutant of Fur(Ec). Like Fur(Ec), Fur(Vh), possesses two cysteine residues at positions 92 and 95, yet unlike Fur(Ec), in which these cysteine residues constitute part of the metal ion coordination site and hence are vital to the repressor activity, C92 and C95 of Fur(Vh) proved to be functionally inessential. Further study identified a Vibrio Fur signature sequence, which is preserved in all the ten Vibrio Fur proteins that have been discovered to date but in none of the non-vibrio Fur proteins. Site-directed and random mutation analyses of the signature residues, the cysteine residues, and seven highly charged amino acid residues indicated that D9, H32, C137, and K138 of Fur(vh) are functionally important but D9, C137, and K138 can be replaced by more than one functional substitutes. Systematic deletion analysis demonstrated that the C-terminal 12 residues of Fur(Vh) are functionally inessential. These results (i) indicated that the activation mechanism, or certain aspects of which, of Fur(Vh) is possibly different from that of Fur(Ec); and (ii) suggested that it is not very likely that the C-terminal 12 residues play any significant role in the activation or stability of Fur(Vh); and (iii) provided insights into the potential function of the local structure involving C137 and K138.

Yeast screens identify the RNA polymerase II CTD and SPT5 as relevant targets of BRCA1 interaction.

BRCA1 has been implicated in numerous DNA repair pathways that maintain genome integrity, however the function responsible for its tumor suppressor activity in breast cancer remains obscure. To identify the most highly conserved of the many BRCA1 functions, we screened the evolutionarily distant eukaryote Saccharomyces cerevisiae for mutants that suppressed the G1 checkpoint arrest and lethality induced following heterologous BRCA1 expression. A genome-wide screen in the diploid deletion collection combined with a screen of ionizing radiation sensitive gene deletions identified mutants that permit growth in the presence of BRCA1. These genes delineate a metabolic mRNA pathway that temporally links transcription elongation (SPT4, SPT5, CTK1, DEF1) to nucleopore-mediated mRNA export (ASM4, MLP1, MLP2, NUP2, NUP53, NUP120, NUP133, NUP170, NUP188, POM34) and cytoplasmic mRNA decay at P-bodies (CCR4, DHH1). Strikingly, BRCA1 interacted with the phosphorylated RNA polymerase II (RNAPII) carboxy terminal domain (P-CTD), phosphorylated in the pattern specified by the CTDK-I kinase, to induce DEF1-dependent cleavage and accumulation of a RNAPII fragment containing the P-CTD. Significantly, breast cancer associated BRCT domain defects in BRCA1 that suppressed P-CTD cleavage and lethality in yeast also suppressed the physical interaction of BRCA1 with human SPT5 in breast epithelial cells, thus confirming SPT5 as a relevant target of BRCA1 interaction. Furthermore, enhanced P-CTD cleavage was observed in both yeast and human breast cells following UV-irradiation indicating a conserved eukaryotic damage response. Moreover, P-CTD cleavage in breast epithelial cells was BRCA1-dependent since damage-induced P-CTD cleavage was only observed in the mutant BRCA1 cell line HCC1937 following ectopic expression of wild type BRCA1. Finally, BRCA1, SPT5 and hyperphosphorylated RPB1 form a complex that was rapidly degraded following MMS treatment in wild type but not BRCA1 mutant breast cells. These results extend the mechanistic links between BRCA1 and transcriptional consequences in response to DNA damage and suggest an important role for RNAPII P-CTD cleavage in BRCA1-mediated cancer suppression.

La función seno mediada por la calculadora TI-92+

Se presentan en este reporte algunos resultados obtenidos en el aula de matemática a propósito del desarrollo de la situación problema: ¿Qué relación existe entre el ángulo en posición normal y el cociente del lado opuesto y la hipotenusa del triángulo rectángulo? (Fig. 1) Esta actividad se implementó con el objetivo de contribuir al desarrollo del pensamiento variacional de los alumnos de 10º grado jornada de la tarde del Colegio Nacional Loperena de Valledupar, a través de la mediación instrumental de la calculadora algebraica TI-92+ y el uso de las distintas representaciones semióticas para movilizar el aprendizaje de la red conceptual subyacente a la función Seno.

La calculadora TI 92 plus y el CBR en la modelación del movimiento pendular

La introducción a la clase de matemáticas de la calculadora TI 92 Plus y otros dispositivos, tales como el CBR, están generando una nueva cultura matemática, caracterizar algunos rasgos de éste fenómeno educativo en la modelación del movimiento pendular es el propósito central de la presente investigación. El trabajo de los estudiantes permitió observar en la práctica los constitutivos del marco teórico del proyecto de incorporación de nuevas tecnologías al currículo de matemáticas de Colombia, como son: mediación instrumental, representaciones ejecutables, cognición situada, solución de problemas, fluidez algorítmica y fluidez conceptual.

Enseñanza de la trigonometría partiendo de la proporcionalidad, mediante la implementación de la calculadora TI-92 plus: una experiencia en el aula

En el trabajo que hemos venido realizando en las pasantías de extensión, pretendemos desarrollar parte de la trigonometría desde la época griega hasta la actualidad; tomando como eje central la proporcionalidad, basados en una metodología de resolución de problemas e implementado la calculadora T.I.- 92 Plus en el aula. Para llevar a cabo este proyecto, diseñamos una serie de actividades enfocadas a desarrollar el concepto de proporcionalidad, trabajando desde la semejanza de triángulos. Este enfoque permite al estudiante, por medio de sus experiencias, construir un conjunto de herramientas que le contribuya no sólo enfrentarse a una situación problema, sino que también le ayude a desarrollar su comprensión y habilidad matemáticas.

Actividades elementales en la calculadora graficadora (Ti - 89, Ti – 92 Plus, Voyage 200)

Actualmente la influencia que tiene la tecnología en la Educación Matemática como medio facilitador tanto en el proceso de aprendizaje como en el de enseñanza de algunas temáticas de las matemáticas escolares, ha generado su inclusión en las instituciones educativas como es el caso, de las calculadoras graficadoras. No obstante, en general son varios los profesores de matemáticas que aunque cuentan con este tipo de recursos para desarrollar sus clases, se abstienen de utilizarlos porque no saben cómo ni en qué momento hacerlo. Por tanto, se presenta algunas actividades sobre ciertas temáticas de la matemática escolar en donde sea factible el uso de herramientas básicas de la calculadora.

Ajuste de una curva a un conjunto de datos con la calculadora TI-92

El articulo trata de resolver el problema de ajuste de una curva a un conjunto de datos que se obtienen a partir de diferentes observaciones de la posición de un asteroide de su órbita alrededor del Sol.